Ursus arctos (brown bear): 113252538
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Entry
113252538 CDS
T05909
Symbol
HSD17B2
Name
(RefSeq) 17-beta-hydroxysteroid dehydrogenase type 2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah00140
Steroid hormone biosynthesis
uah01100
Metabolic pathways
uah04913
Ovarian steroidogenesis
Module
uah_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
113252538 (HSD17B2)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
113252538 (HSD17B2)
Enzymes [BR:
uah01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
113252538 (HSD17B2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
113252538 (HSD17B2)
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Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
Epimerase
Motif
Other DBs
NCBI-GeneID:
113252538
NCBI-ProteinID:
XP_026351099
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All DBs
Position
Unknown
AA seq
380 aa
AA seq
DB search
MGTSFSGTAWLCLAVTVVLGGLALCHLKSPGRAGRKVVCLAGFWGGAYLLLSLPLSWGLL
LCLLCCFLTYTYLSGQELLPVEQKAVLITGGDSGFGHAVSKYLDELGFTVFVGVLDEKGS
GAEELRRTCSKHLSVLQMDITDPQQIKDAHSKVVEKVQNRGLWAVVNNAGIIGLPADGEL
IPMTEYKKCMAVNFFGAVEVTKAFLPLLRKSKGRLVNISSMAGGVPMEKLAAYSSSKAAL
TMFSAVLRQELSKWGVKVSVIQPGGFRTNIAGTSEMWSKQEKDILDHLTSDVQEDYGQDY
ILEQRNFLKLINTMANTDMSPVLLDIRHAVSAKSPFAFYAPGPMAYSLLCFVSFSPTGIF
DYFIKKWYRSIGALPRALIK
NT seq
1143 nt
NT seq
+upstream
nt +downstream
nt
atgggcacgtccttctctgggaccgcgtggctctgcctggctgtcaccgtagtgctggga
ggactagctctttgccatctcaagagcccagggcgggctggcagaaaggtggtctgcctg
gctggcttctggggaggggcttacctgctgctcagcctgcccctctcctggggcttgctc
ctctgtctcctgtgctgtttcctcacgtacacttacctgtccggtcaggagctgttacct
gtggagcagaaggcggtgctgatcacaggtggcgattccggatttggccatgctgtgtcc
aaatatctggatgagctcggcttcacagtatttgtgggagttctggatgaaaagggatca
ggagcagaggaattgcgcaggacctgctccaagcacctctctgtgctccagatggacatc
actgacccgcagcagataaaagacgcccacagcaaagtggtggaaaaggtgcagaacaga
ggactgtgggctgtggtcaacaacgctgggatcattggcttaccagccgacggggagctc
attcccatgactgagtacaaaaaatgcatggctgtgaacttcttcggggctgtggaggtc
acgaaggcatttttgcctcttcttaggaaatccaagggcaggctggtgaacatcagcagc
atggcaggaggggtcccaatggaaaagctggcagcctatagctcatccaaggcagctctg
accatgttctcagcagtcctgagacaagagctttccaaatggggagttaaagtctctgtc
atccagcccggaggcttcagaacgaatatcgcaggcacgagtgaaatgtggagcaagcag
gagaaggacatcctggaccaccttacctccgatgtgcaggaggattatggccaggactat
atccttgagcaacggaattttcttaaactcatcaacacgatggccaacacagatatgtcc
cctgtgctcctggacatccgacatgccgtgtctgctaagagcccctttgccttttatgca
ccagggccaatggcttattcattgctctgctttgtttcctttagtcctactggcatattt
gattattttatcaaaaaatggtatcgctctataggggccttgcccagagcgcttattaag
tag
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