Ursus arctos (brown bear): 113253260 Help Entry 113253260         CDS       T05909                                  Symbol TYMS Name (RefSeq) thymidylate synthase isoform X2   KO K00560   thymidylate synthase [EC:2.1.1.45] Organism uah  Ursus arctos (brown bear) Pathway uah00240   Pyrimidine metabolism uah00670   One carbon pool by folate uah01100   Metabolic pathways uah01232   Nucleotide metabolism uah01523   Antifolate resistance uah04981   Folate transport and metabolism Module uah_M00938   Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP Brite KEGG Orthology (KO) [BR:uah00001]  09100 Metabolism   09104 Nucleotide metabolism    00240 Pyrimidine metabolism     113253260 (TYMS)   09108 Metabolism of cofactors and vitamins    00670 One carbon pool by folate     113253260 (TYMS)  09150 Organismal Systems   09154 Digestive system    04981 Folate transport and metabolism     113253260 (TYMS)  09160 Human Diseases   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     113253260 (TYMS) Enzymes [BR:uah01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.1  Methyltransferases     2.1.1.45  thymidylate synthase      113253260 (TYMS) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Thymidylat_synt Motif Other DBs NCBI-GeneID:  113253260 NCBI-ProteinID:  XP_026351839 LinkDB All DBs Position Unknown AA seq 316 aa AA seqDB search MPAPGSQLQRPPSPSPPAAQKPGAEPQPPPHGELQYLGQIEHILRCGVRKDDRTGTGTLS VFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKDLSSKGVKIWDANGSRDF LDSLGFCNREEGDLGPVYGFQWRHFGAEYKDKDSDYSGQGVDQLQKVIDTIKTNPDDRRI ILCGWNPKDLPLMALPPCHALCQFYVGNGELSCQLYQRSGDMGLGVPFNIASYALLTYMI AHVTGLKPGDFVHTLGDAHIYLNHIEPLKMQLQREPRPFPKLKILRKVETIDDFKAEDFQ IEGYSPHPTIKMEMAV NT seq 951 nt NT seq  +upstreamnt  +downstreamnt atgcccgcccccggctcccagctgcagcgtccgccgtcgccgtcgccgcccgccgcgcag aaaccgggcgccgagccgcagccgccaccccacggggagctgcagtacctggggcagatc gagcatatcctgcgctgcggggtccggaaggatgaccgcacaggcacgggcacgctgtcc gtgttcggcatgcaggcgcgctacagcctgagagatgaatttcctctgctgacaaccaaa cgagtattctggaagggtgttttggaggagctgctgtggtttatcaagggatctacaaac gctaaggacctgtcttccaagggagtgaaaatctgggacgccaacgggtctcgagacttc ttggacagcctgggattctgcaacagagaagaaggggatttaggcccagtttatggcttt cagtggaggcattttggggcagaatacaaagataaggattcagattattcaggtcaagga gtagaccagctgcaaaaggtgattgacacaatcaaaaccaaccccgatgacagaagaatc atcctgtgcggctggaatccaaaagatcttcctctgatggcccttcctccgtgccatgcc ctctgccagttctacgtggggaacggcgagctgtcctgccagctgtaccagcggtcgggg gacatgggcctgggcgtgcccttcaacatcgccagctacgccctgctcacctacatgatt gcgcacgtcaccggcctgaagccaggtgacttcgtacatactttgggagatgcacatatt tacctgaatcacattgagccgctgaaaatgcagcttcagcgagaaccaaggcctttcccg aagctcaaaatccttcgaaaagttgagacaatcgatgacttcaaggctgaagactttcag attgaggggtacagtcctcacccgactattaaaatggaaatggctgtttaa

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