Ursus arctos (brown bear): 113253847
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Entry
113253847 CDS
T05909
Symbol
TGFBR2
Name
(RefSeq) TGF-beta receptor type-2 isoform X1
KO
K04388
TGF-beta receptor type-2 [EC:
2.7.11.30
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah04010
MAPK signaling pathway
uah04060
Cytokine-cytokine receptor interaction
uah04068
FoxO signaling pathway
uah04144
Endocytosis
uah04218
Cellular senescence
uah04350
TGF-beta signaling pathway
uah04380
Osteoclast differentiation
uah04390
Hippo signaling pathway
uah04520
Adherens junction
uah04659
Th17 cell differentiation
uah04926
Relaxin signaling pathway
uah04933
AGE-RAGE signaling pathway in diabetic complications
uah05142
Chagas disease
uah05161
Hepatitis B
uah05166
Human T-cell leukemia virus 1 infection
uah05200
Pathways in cancer
uah05202
Transcriptional misregulation in cancer
uah05210
Colorectal cancer
uah05212
Pancreatic cancer
uah05220
Chronic myeloid leukemia
uah05225
Hepatocellular carcinoma
uah05226
Gastric cancer
uah05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
113253847 (TGFBR2)
04350 TGF-beta signaling pathway
113253847 (TGFBR2)
04390 Hippo signaling pathway
113253847 (TGFBR2)
04068 FoxO signaling pathway
113253847 (TGFBR2)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
113253847 (TGFBR2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
113253847 (TGFBR2)
09143 Cell growth and death
04218 Cellular senescence
113253847 (TGFBR2)
09144 Cellular community - eukaryotes
04520 Adherens junction
113253847 (TGFBR2)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
113253847 (TGFBR2)
09152 Endocrine system
04926 Relaxin signaling pathway
113253847 (TGFBR2)
09158 Development and regeneration
04380 Osteoclast differentiation
113253847 (TGFBR2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113253847 (TGFBR2)
05202 Transcriptional misregulation in cancer
113253847 (TGFBR2)
09162 Cancer: specific types
05210 Colorectal cancer
113253847 (TGFBR2)
05212 Pancreatic cancer
113253847 (TGFBR2)
05225 Hepatocellular carcinoma
113253847 (TGFBR2)
05226 Gastric cancer
113253847 (TGFBR2)
05220 Chronic myeloid leukemia
113253847 (TGFBR2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
113253847 (TGFBR2)
05161 Hepatitis B
113253847 (TGFBR2)
09174 Infectious disease: parasitic
05142 Chagas disease
113253847 (TGFBR2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
113253847 (TGFBR2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
113253847 (TGFBR2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uah01001
]
113253847 (TGFBR2)
Enzymes [BR:
uah01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
113253847 (TGFBR2)
Protein kinases [BR:
uah01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR2 family [OT]
113253847 (TGFBR2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ecTbetaR2
PK_Tyr_Ser-Thr
Pkinase
ABC1
Haspin_kinase
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
113253847
NCBI-ProteinID:
XP_026352640
LinkDB
All DBs
Position
Unknown
AA seq
567 aa
AA seq
DB search
MGRGLLRGLWPLHIVLWTRIASTIPPQVQKSVNNDMMVTDNNGVIKFPQLCKFCDVRSST
CDNQKSCVSNCSITSICEKPHEVCLAVWRKNDENITLETLCHDPKDTYHGIVLEDSASPK
CIMKEKKVLGETFFMCSCSSDECNDYIIFSEEYATNNPDLLLVIFQVTGVSLLPPLGIAI
AVIVTFYCYRVHRQQKLSPSWETSKPRKLMEFSEHLAIILEDDRSDISSTCANNINHNTE
LLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLK
HENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAH
LHSDHTLCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVG
TARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVRE
HPCVESMKDNVLRDRGRPEIPSSWLNHQGIQTVCETLTECWDHDPEARLTAQCVAERFSE
LEHLDRLSGRSCSEEKIPEDGSLNTTK
NT seq
1704 nt
NT seq
+upstream
nt +downstream
nt
atgggtcgggggctgctcaggggcctgtggccgctgcacatcgtcctgtggacgcgcatc
gccagcacgatcccgccgcaagttcagaagtcggttaataatgacatgatggtcaccgac
aacaatggtgtcatcaaatttccacaattgtgtaaattttgcgatgtgagatcttccacc
tgtgacaatcagaaatcctgcgtgagcaactgcagcattacatccatctgtgagaagcca
catgaagtctgtctggcggtctggagaaagaatgatgagaacataacactagagacgctt
tgccatgaccccaaggacacctaccacggaatcgttctcgaagattctgcttctccaaag
tgtattatgaaggaaaaaaaggtgttgggcgagactttctttatgtgttcctgtagctct
gatgagtgcaatgactacatcatcttctcggaagaatatgccaccaacaaccctgacctg
ttgttagtcatatttcaagtgacaggcgtcagcctcctgccaccactgggaatcgccata
gccgtcattgtcaccttctactgctaccgggttcaccggcagcagaagctgagcccgtcc
tgggagaccagcaagccacggaagctcatggagttcagcgagcacctggccatcattctg
gaagacgaccgctccgacatcagctctacctgcgccaacaacatcaaccacaacacagag
ctgctgcccattgagctggacaccctggtggggaaaggtcgcttcgccgaggtctacaag
gccaagctgaagcagaacacttcagaacagttcgagaccgtggcggtcaagatcttccct
tatgaggagtacgcctcctggaagacagagaaggacatcttctcagacatcaacctgaag
catgagaacatcctgcagttcctgacggccgaggagcggaagacagagctggggaagcag
tattggctgatcacagccttccacgccaagggcaacctacaggagtacctcacgcggcac
gtcatcagctgggaggacctgcgcaagctgggcagctccctcgcccggggcattgctcac
ctgcacagtgaccataccctgtgcgggaggcccaagatgcccatcgtgcacagggacctc
aagagctccaatatcctcgtcaagaacgacctgacctgctgcctgtgtgactttgggctt
tccctgcgcctcgacccgactctgtctgtggatgacctggccaacagtgggcaggtggga
actgcaagatacatggctccagaagtcctagagtccaggatgaatctggagaacgttgaa
tcctttaagcagacggatgtctactccatggctctggtactctgggaaatgacatctcgc
tgcaatgcggtgggagaagtgaaagattacgagcctccatttggttccaaggtgcgggag
catccttgtgttgagagcatgaaggacaacgtgctgagagaccgagggcgaccagaaatt
cccagctcctggctcaaccaccagggcatccagacggtgtgcgaaactctgaccgagtgc
tgggaccacgacccggaggcccggctcacggcccagtgcgtggcggagcgcttcagcgaa
ctggagcacctggacaggctctcagggaggagctgctccgaggagaagattcccgaagat
ggctcgctgaacactaccaaatag
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