Ursus arctos (brown bear): 113253866
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Entry
113253866 CDS
T05909
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
113253866 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
uah03032
]
113253866 (TOP2B)
03036 Chromosome and associated proteins [BR:
uah03036
]
113253866 (TOP2B)
Enzymes [BR:
uah01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
113253866 (TOP2B)
DNA replication proteins [BR:
uah03032
]
Eukaryotic type
DNA Topoisomerases
113253866 (TOP2B)
Chromosome and associated proteins [BR:
uah03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
113253866 (TOP2B)
Centrosome formation proteins
Centriole proteins
113253866 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Motif
Other DBs
NCBI-GeneID:
113253866
NCBI-ProteinID:
XP_026352679
LinkDB
All DBs
Position
Unknown
AA seq
1621 aa
AA seq
DB search
MAKAGGGGGAGAGGNGALTWVTLFDQNNAAKKEESETANKNDSSKKLSVERVYQKKTQLE
HILLRPDTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKN
MTCIKVSIDPESNIVSIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGG
RNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQP
DLSKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDE
TGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVV
KKKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKA
ASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTE
GDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKS
YDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKAS
KNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYA
GPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINK
ELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGE
QALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLSRLLFPAV
DDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLD
GLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLE
PMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMV
LFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQG
KITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTPSGPD
FNYILNMSLWSLTKEKVEELIKQRDSKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQ
EREDILAGMAGKAIKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADASKKLLKKKK
GDLDTTAVKVEYDEEFSGTPVEGTGEEALIPSAPVNKGPKPKREKKEPGTRVRKTPTSAG
KSSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDA
DDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSSHDKKSQD
FGTLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDT
TAKPKRAPKQKKVEPINSDSDSEFGIPKKTTPPKGKGRGAKKRKASGSENEGDYNPGRKT
SRTASKKPKKTSFDQDSDVDIFPSDFTSEPPSLPRTGRARKEVKYFAESDEEEDVDFAMF
N
NT seq
4866 nt
NT seq
+upstream
nt +downstream
nt
atggccaaggcgggcggcggcggcggcgctggagccggcggcaacggggcactgacctgg
gtgactctttttgatcagaacaatgctgcaaaaaaagaagagtcagaaactgcaaacaaa
aatgattcttcaaagaagttgtctgttgagagagtgtatcagaaaaagacacaacttgaa
catattctccttcgtcctgatacatatattgggtcagtggaaccattgacacagctaatg
tgggtatatgatgaagatgtaggaatgaattgcagagaggttacctttgtgccaggttta
tacaagatctttgatgaaattttggttaatgcagctgacaacaaacagagggataagaat
atgacctgtattaaagtttctattgatcctgaatcaaatattgtaagcatttggaataat
gggaaaggcattccagtagtagaacacaaagtagagaaagtttatgttcctgcgttaatt
tttggacagcttttaacatccagtaactatgatgatgatgagaaaaaagtaacaggtggt
cgcaatggttacggtgcaaaactttgtaatattttcagtacaaagtttacagtagaaact
gcttgcaaagaatacaaacatagttttaagcagacatggatgaataacatgatgaagact
tctgaagccaaaattaagcattttgatggtgaagattatacatgcataacattccaacca
gatctgtctaaatttaagatggaaaaacttgacaaggatattgtggccctcatgaccaga
agagcttatgatttggctggttcatgcaagggggtcaaggtcatgtttaatgggaagaaa
ttgcccgtaaatggatttcgcagttatgtagatctttatgtgaaagacaagttggatgaa
actggagtggccctgaaagttattcatgaacttgcaaatgaaagatgggatgtttgtctc
acgcttagtgaaaagggattccagcaaatcagctttgtaaatagtattgcaacaacaaaa
ggtggacgtcacgtggattatgtggtagatcaagttgttggtaaactaattgaagtagtt
aagaaaaagaacaaagctggtgtatcagtaaaaccatttcaagtgaaaaaccatatatgg
gtttttattaattgtcttatcgaaaatccaacttttgattctcaaactaaagaaaacatg
actctgcaacccaaaagttttgggtccaaatgccaactgtcagaaaaattttttaaagca
gcttctaactgtggcattgtagaaagtattctgaattgggtgaaatttaaggctcagact
cagctgaacaagaagtgttcatcagtgaagtatagtaaaatcaaaggtattcccaaactg
gatgacgctaatgatgctggtggcaaacattccctggagtgtacactgatactaacagag
ggcgactctgccaaatcgttggctgtgtctggattaggtgtgattgggcgagacagatat
ggagtctttccacttaggggaaaaattcttaacgtacgggaagcttctcataaacagatc
atggaaaatgcagaaataaacaatattattaaaatagttggtctacagtacaagaaaagt
tatgatgatgcagaatctctgaaaactttacgctatgggaaaattatgattatgactgat
caggatcaagatggttctcacataaaaggcctgcttattaatttcatccatcacaattgg
ccatcacttttgaagcatggttttcttgaagagttcattactcctattgtaaaggctagc
aaaaataagcaggaactttccttctatagtattcctgaatttgatgaatggaaaaaacat
atagaaaaccagaaagcctggaaaataaaatactacaaagggttgggtaccagtacagcc
aaagaagcaaaggaatattttgctgatatggaaaggcaccgcatcttgtttagatatgct
ggtcccgaagatgatgctgccattaccttggcattcagtaaaaagaagattgatgacaga
aaagaatggttaacaaatttcatggaagaccggagacagcgtaggttacatggcttacca
gagcaatttttgtatggtacagcaacaaagcatttgacttacaatgatttcatcaacaag
gaattgattctcttctcaaactcagacaatgaaagatctataccatctcttgttgatggt
tttaaaccaggacaacgaaaagttttatttacctgtttcaagaggaatgataaacgtgaa
gtaaaagttgcccagttggctggatctgttgcggaaatgtctgcttatcatcatggagaa
caagcattgatgatgacgattgtgaatttggctcagaactttgtgggaagcaacaacatt
aacttgcttcagcctattggtcagtttggaactcggcttcatggtggcaaagatgctgca
agccctcgttatattttcacaatgttaagctctttatcaagactgctttttcctgctgtg
gatgacaacctgcttaaattcctttatgatgataatcaacgtgttgagcctgagtggtat
attcctattattcccatggttttaataaatggtgctgagggcattggtactggatgggct
tgtaaactacccaactatgatgctagggaaattgtgaacaatgtcagacgaatgctagat
ggcttggatcctcatcctatgcttccgaactacaaaaacttcaaaggaaccatccaagag
cttggtcaaaaccagtatgctgtcagtggtgaaatatttgtggtggatagaaacacagta
gagattacagagcttccagttagaacttggacacaggtatacaaagaacaggttttagaa
cctatgctaaatggaacagataaaacaccggcattaatttctgattataaagaatatcat
actgatacaactgtgaaatttgtggtgaaaatgactgaagagaagctagcacaagcagaa
gctgctggattgcacaaagtttttaaacttcagactactcttacttgtaattccatggta
ctctttgatcatatgggatgtctcaagaagtatgaaaccgtgcaagacattttgaaagaa
ttctttgatttacgattaagttattatggtttacgtaaggagtggcttgtaggaatgttg
ggagcagagtctacaaagcttaacaatcaagcccgtttcattttagagaagatacaagga
aaaattactatagagaataggtcaaagaaagatttgattcaaatgttagtccagagaggt
tatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagaggaa
gaaacacaaaaccagcatgatgatagttcctctgattcaggaactccttcaggccccgat
tttaattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaactg
attaaacagagagattcaaaagggcgagaggtcaatgatcttaaaagaaaatctccttca
gatctttggaaagaagacttagcagcatttgttgaagaactggataaagtggaagcgcaa
gaacgagaggatattctggctggaatggctggaaaagcaataaaaggtaaagttggcaaa
cctaaggtgaagaaacttcaattggaagagacaatgccctcaccttatggaagaagaata
gttcctgaaattactgctatgaaggcagatgccagcaaaaagttgctgaagaagaaaaag
ggtgatcttgataccacagcagtaaaagtagaatatgatgaagaattcagtggaacaccg
gtagagggtactggagaagaggcgttgatcccttcagctcctgtaaataaaggtcccaaa
cccaaaagggagaaaaaggagcctggtaccagggtgagaaaaacacctacatcagctggt
aaatccagtgcaaagaaagtgaagaaacggaatccttggtcagatgatgaatccaagtca
gaaagtgacttggaagaaacagaacctgtggttattccaagagattcgttgcttaggaga
gcagctgctgaaaggcctaagtacacatttgatttctcagaagaagaggatgatgatgct
gatgatgacgacgacaataatgatttagaggaattgaaagttaaagcatctcccataaca
aatgatggggaagatgaatttgttccttcagatggcctagataaagatgaatatacattt
tcaccaggcaaatcaaaagctactccagaaaaatcttcacatgacaaaaaaagtcaagat
tttgggactctcttctcatttccttcatactctcagaagtcagaagatgattcagctaag
tttgacagtaatgaagaagattctgcctctgttttttcaccatcatttggtctgaaacaa
acagataaagttccaagtaaaacagtagctgctaaaaagggaaaaccgtcttcagataca
actgctaagcccaagagagcccctaaacagaagaaagtagagcctatcaactctgactca
gattcagaatttggcattccaaagaagactacacccccaaaaggtaaaggccgaggggca
aagaaaaggaaagcatctggctctgaaaacgaaggtgactataaccctggcaggaaaaca
tccagaacagcaagcaagaaaccgaagaaaacatcttttgatcaggattcagatgtggac
atcttcccatcagacttcacttctgaaccaccttctctgccacggaccggtagggctagg
aaagaagtaaaatattttgcagagtctgatgaagaagaagatgttgattttgcaatgttt
aattaa
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integrated database retrieval system
