Ursus arctos (brown bear): 113254017
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Entry
113254017 CDS
T05909
Symbol
ATR
Name
(RefSeq) serine/threonine-protein kinase ATR isoform X1
KO
K06640
serine/threonine-protein kinase ATR [EC:
2.7.11.1
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah03460
Fanconi anemia pathway
uah04110
Cell cycle
uah04115
p53 signaling pathway
uah04218
Cellular senescence
uah05165
Human papillomavirus infection
uah05166
Human T-cell leukemia virus 1 infection
uah05170
Human immunodeficiency virus 1 infection
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09120 Genetic Information Processing
09124 Replication and repair
03460 Fanconi anemia pathway
113254017 (ATR)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
113254017 (ATR)
04115 p53 signaling pathway
113254017 (ATR)
04218 Cellular senescence
113254017 (ATR)
09160 Human Diseases
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
113254017 (ATR)
05170 Human immunodeficiency virus 1 infection
113254017 (ATR)
05165 Human papillomavirus infection
113254017 (ATR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uah01001
]
113254017 (ATR)
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
uah03400
]
113254017 (ATR)
Enzymes [BR:
uah01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
113254017 (ATR)
Protein kinases [BR:
uah01001
]
Serine/threonine kinases: Other
PIKK family [OT]
113254017 (ATR)
DNA repair and recombination proteins [BR:
uah03400
]
Eukaryotic type
Check point factors
Other check point factors
113254017 (ATR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
N-HEAT_ATR
PI3_PI4_kinase
FAT
M-HEAT_ATR
HEAT_ATR
UME
FATC
HEAT
Mad3_BUB1_I
THP2
Motif
Other DBs
NCBI-GeneID:
113254017
NCBI-ProteinID:
XP_026352966
LinkDB
All DBs
Position
Unknown
AA seq
2644 aa
AA seq
DB search
MGDHGLELASMIPALRELGSASPEEYNTVVQKPRQILCQFIDRILTDVNVVALELVKKTD
SQPTSVMLLDFIQHIMKSSPLMFVNVNGSQGQNEAKGSCIEFSNWIITRLLRIAATPSCH
MLHKKICEVICSLLFLFKSKSPAIFGVLTKELLHLFEDVIYLHRKNAVGHFVEWPVVVSR
FSSQLDEHVGYLQPAPLQFVNMQNLEFIEVTLLTVLIRIVAIVFFRRQELFLWQIGCVLL
EYGSPKIKSLAISLLTELFELGGLPAQPASTFFSSFLGLLKHLVEMDADQLKLYEEPLSK
LIRTLFPFEAEAYRNIEPVYLNMLLEKLCVMFEDGVLMRLKSDLLKAALCHLLQYFLKYV
PAGYESALQVRKVYVRNICRVLVDVLGFQVDAEYLLGPLYAALKMESMEIIEEVQCQIQQ
ENLSSNSDGISAKRRRLSSSLNSSKRPPKQTEEIKHVDMNKKSILWSALKQKAESLQIFL
EYGSLKNPVIATLEGITIVLQLTALCTVHCSHQNMDCHNFKDSQQKYKKKPSVEVTWMSL
DFYTKVLKSCRSLLESVQKPDLEAIIDKVVKIYDALIYIHVKTSFEDHILEDLCGMLSLP
WIHSHSDDGSLKLTTFATNLLALSQRISDSYSPQAQSRCVFLLTLFPRRIFLEWRTAIYS
WALQSSHEVIRASCVNGFFILLQQQNSCNRVPKILIDKVKDDSDTVKKEFASILGQLVCT
LHGMFYLTSSLTEPFSEHGHIDLFCKSLKVTSQHECSSSQLKASLCKPFLFLLKKKSPSP
VKLAFIDNLYHLCKHLDFREDETDVKTVLGTLLNLMEDPDKDVRVAFSGNIKHILESLDS
EDGFIKELFVLRMKEAYTHAQISRNNELKDTLILTTGDIGRAAKGDLVPFALLHLLHCLL
SKSASVSGAAYTEIRALVAAKSVKLQNFFSQYKKPICQFLVESLHSSQMTALPSTPCQNA
EMRKQDVAHQREMALNTLSEIANVFDFPDLNRFLTRTLQVLLPDLAAKASPAASALIRTL
GKQLNVNRREILINNFKYIFSHLVCSCSKDELERALHYLKNETEIELGSLLRQDFQGLHN
ELLLRIGEHYQQVFNGLSILASFASSDDPYQGPREITSPELMADYLQPKLLGILAFFNMQ
LLSSSVGIEDKKMALNSLMSLMKLMGPKHVSSVRVKMMTTLRTGLRFKDDFPELCCRAWD
CFVRCLDHAYLGSLLSHVIVALLPLIQIQPEETAAIFHYLIIENRDAVQDFLHEIYFLPD
HPELKKIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRIHALTSLKETLYKNQEK
LIKYATDSETVEPVISQLVTVLLKGCQDANSQARLLCGECLGELGAIDPGRLDFSTSESQ
GKDFTFVTGVEDSSFAFGLLMELTRAYLAYADNSRAQDSAAYAIQELLSIYDCREMQTDG
PGHQLWRRFPEHVREILEPHLNTRYKSSQKSTDWSGVKKPIYLSKLGNNFAEWSASWAGY
LITKVRHDLASKIFTCCSIMMKHDFKVTIYLLPHILVYVLLGCNQEDQQEVYAEIMAVLK
HDDQHIISTQDSASDLCQLSTQTVFSMLDHLTQWARHKFQALNAEKFPQSKSNRDKVDSV
VSTADYEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITEKKQNIQEHLGFLQ
KLYAAMHEPDGVAGVSAIRKAEPSLKEQILEHESIGLLRDATACYDRAIQLEPDQIIHYH
GVVKSMLGLGQLSTVITQVNGVHANRSEWTDELNTYRVEAAWKLSQWDLVENYLAADGKS
TTWSVRLGQLLLSAKKRDTTAFYDTLKLVRAEQIVPLSAASFERGSYQRGYEYIVRLHML
CELEHSIKPLFHQSPGDSSQEDSLNWVARLEMTQNSYRAKEPILALRRALLSLNKRPDYN
EMVGECWLQSARVARKAGHHQTAYNALLNAGESRLAELYVERAKWLWSKGDVHQALIVLQ
KGVELCFPENKTPTESKNMLIHGRAMLLVGRFMEETANFESNAVMKKYKDVTLFLPEWED
GHFYLAKYYDKLMPMVTDNKMEKQGDLIRYIVLHFGRSLQYGNQFIYQSMPRMLSLWLDF
GAKAYEWEKAGRSDRVQMRNDLAKINKVITEHTNHLAPYQFLTAFSQLISRICHSHDEVF
VVLMEIIAKVFLAYPQQAMWMMTAVSKSSYPMRVNRCKEILNKAIHMKKSLEKFIGDATR
LTDKLLELCNKPVDGSSSTLSMSTHFKMLKKLVEEPTFSEILIPLQSVMIPTLPSIPGAH
ANHDPFPGHWAYIASFDDTVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLME
FNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVY
MTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPVFHEWFLRTFPDPTSWYSSRSAYCRS
TAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMV
NGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSKPVKGHSKAPLNET
GEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGW
TPYM
NT seq
7935 nt
NT seq
+upstream
nt +downstream
nt
atgggcgaccacggcctggagctggcgtctatgatccccgctctgcgggagttgggcagt
gccagtccagaggaatataatacagttgtacagaagccaagacaaattttatgtcagttt
attgaccgaatacttacagatgtaaatgttgttgctctagaacttgtaaagaaaactgac
tctcagccaacctctgtgatgttgcttgatttcatccaacatataatgaagtcctcccca
cttatgtttgtaaatgtgaatggaagccaagggcaaaatgaggccaaaggcagttgtatt
gaattcagtaattggatcataacaagacttctgcggattgcagcaactccatcctgtcat
atgttacacaagaaaatctgtgaagttatctgctcattgttatttctttttaaaagcaag
agccctgcaattttcggagtactgacaaaggaattactacatctttttgaagatgtgatt
tacctccacagaaaaaatgcagtgggacactttgtggaatggccagtggtagttagccga
ttttcaagtcaattagatgaacatgtgggatatttacaaccagctcctttgcaattcgtg
aacatgcaaaatttagaatttattgaagtcactttattaacagttcttattcgtattgtt
gcaattgtgttttttagaaggcaagaactctttctttggcagataggttgtgttctgcta
gagtatggtagtccaaaaattaaatccttagcaattagccttttaaccgaactctttgag
cttggaggattaccagcacaaccagccagcactttcttcagctcatttttaggattatta
aaacatcttgtagaaatggatgctgaccagttgaaactctatgaagaaccattatcaaag
ctgataagaacactgttcccctttgaagcagaagcttatagaaatattgaacctgtctat
ttaaatatgctgctggaaaaactctgtgtcatgtttgaagatggtgtgcttatgcggctt
aagtctgatttgctaaaagcagctttgtgccacttactgcagtatttccttaaatatgtg
ccagctgggtatgaatctgctctacaagtcaggaaggtttatgtgagaaacatttgtaga
gttcttgtggatgtgcttggatttcaggtagatgcagagtatttgttgggcccactttat
gcagccttaaaaatggaaagtatggaaatcattgaggaggttcaatgccaaattcaacag
gaaaacctcagcagtaatagtgatgggatatcagccaaaaggcgtcgactcagctcatct
ctaaactcttccaaaagaccaccaaaacagactgaggaaattaaacatgtggatatgaac
aagaagagcatattatggagtgccctgaaacagaaagctgagtcccttcagattttcctt
gaatatggtagtctaaagaatcctgttattgcaactttggaaggaatcactattgtccta
cagctgactgctctgtgtactgttcattgttctcatcaaaacatggactgccataatttc
aaggacagtcaacagaaatataagaagaaaccttcagtagaggtaacttggatgtctttg
gatttttacacaaaagtgcttaagagctgtaggagtttgttagaatctgttcagaagccc
gacctggaggcaattattgataaagtggtgaaaatatatgatgctctgatttatattcac
gtgaaaacttcttttgaagatcatattctggaagatttatgtggaatgctctcacttcca
tggattcattcccattctgatgatggctctttaaagttgaccacatttgccactaatctt
ttagcattaagccagaggatttcagatagctactcaccacaggcacagtcacggtgtgtg
tttcttctaactttgtttccaagaagaatattccttgaatggagaacagcaatttatagc
tgggccctacagagctcccatgaagtaatccgagctagttgtgttaatggattttttatc
ttattgcagcagcagaattcatgtaacagagttcccaagattcttatagataaagtcaaa
gatgattctgacactgtcaagaaagaatttgcctctattcttggtcagcttgtctgtacg
cttcatggcatgttttatttgacaagttctttaacagaacctttctctgagcatggacat
attgacctcttctgtaaaagccttaaagtcacttctcaacatgaatgttcatcttctcaa
ctaaaagcttctctttgcaaacctttccttttcctactgaaaaaaaaatcacctagtcca
gtgaaacttgctttcatagataatctatatcatctttgtaagcaccttgattttagagaa
gatgaaacagatgtgaaaacagttcttggaactttattaaatttaatggaagatccagac
aaggatgtgagagtggcttttagtggaaatatcaagcacatattggaatccttggactct
gaagatggatttataaaagagctttttgtcttaagaatgaaggaagcatatacacatgct
caaatctcaagaaataatgagttgaaggataccttgattcttacaacaggggatattgga
agggcagcaaaaggagatttggtaccttttgcacttttgcatttattgcattgtttatta
tcgaagtcggcatctgtctctggagcagcatatacagaaatcagagctttggttgcagct
aagagtgttaaactgcaaaactttttcagccagtataagaaacccatctgtcagttttta
gtagaatccctccattccagtcagatgacagcacttcctagtactccatgccagaatgct
gagatgcggaaacaagatgtggctcaccagagagaaatggctttaaataccttgtctgaa
attgccaatgtttttgactttcctgatcttaatcgtttccttactaggacattacaagtt
ctgctacctgaccttgccgccaaagcaagccctgcagcttctgctctcattcgaacttta
ggaaaacaattaaatgtcaatcgtagagagattttaataaataacttcaaatatattttt
tctcatttggtctgttcctgttccaaggatgaattagaacgtgcccttcattatctgaag
aatgaaacagaaattgaactggggagtctattgagacaagatttccaaggattgcataat
gaattattgctacgtattggagaacactatcaacaggttttcaatggtttgtcaatactt
gcctcatttgcatctagtgatgatccatatcagggccccagagagatcacatcacccgaa
ttaatggctgactatttgcaacctaagttgttgggcattttggccttttttaacatgcag
ttactgagctccagtgttggcattgaagataagaaaatggctttgaacagtttgatgtct
ttgatgaagttgatgggaccaaaacacgtcagttctgtgagggtgaagatgatgaccacg
ctaagaactggcctgagattcaaggatgattttcccgaattgtgttgtagagcttgggat
tgctttgttcgttgcctggatcatgcttatcttgggtcccttctcagtcatgtgatagta
gctttgttacctctcatacaaatccagcctgaagaaactgcagccatatttcactacctc
ataattgaaaacagggatgctgtacaagattttcttcatgaaatatattttttacctgat
catccagaattaaaaaagataaaagcagttctacaggaatacagaaaggagacctcagag
agtacagatcttcagacaactctacaattatccatgaaagcaattcaacatgaaaatgta
gatgttcgtattcatgctcttacgagtttgaaggaaactttatataaaaatcaggaaaaa
ctgataaaatatgcaacagatagcgaaacagtggaacctgttatctcacagttggtgaca
gtgcttttgaaaggttgccaagacgcaaactctcaagctcggttgctctgtggggaatgt
ttaggggaattgggggcaatagatccaggtcgactagatttttcaacaagtgaaagccaa
ggaaaagattttacatttgtgactggagtagaagattcaagctttgcctttggattattg
atggaactaacaagagcttaccttgcatatgcagataatagccgggctcaagattcagct
gcttacgccattcaggagttactttctatttatgactgtagagagatgcagaccgatggc
ccaggtcaccagttgtggaggagatttcctgagcatgttcgggaaatcctggaacctcat
ctaaatactagatataagagttctcagaagtcaacagattggtctggagtaaagaagcca
atttacttaagtaaattaggtaataactttgcagaatggtcagcatcttgggcaggttat
cttataacaaaggttcggcatgatcttgccagtaaaatcttcacctgctgtagcattatg
atgaaacatgatttcaaggtgaccatctatcttcttccacatattctagtgtatgtcttg
ttgggttgtaatcaagaagatcagcaagaggtttatgcagaaattatggcagttctaaag
catgatgatcaacatatcataagtacccaagacagtgcatctgatctgtgtcaactcagt
acacagactgtcttctccatgcttgaccatctcacacaatgggcaaggcacaaatttcag
gcactgaatgcagagaaatttccacaaagcaaatcaaacagagataaagtagactcagta
gtatctactgcggattatgaagactatcagagtgtaactcgttttctagacctcatacct
caggataccctggcagtagcttcctttcgctccaaagcatacacacgagctgtaatgcac
tttgaatcatttattacagaaaagaaacaaaatattcaagaacatcttggatttttacag
aaattgtatgctgctatgcatgaaccagatggagtggctggagtaagcgcaattcgaaag
gcagaaccatctctcaaagaacagatccttgaacatgaaagcattggcttactgagggat
gccactgcttgttatgacagggctattcagctagaaccagaccagatcattcattatcat
ggtgtagtgaagtccatgttaggtcttggtcagctgtctaccgtaatcactcaggtgaat
ggagtacatgctaacaggtctgaatggacagatgaattaaacacatacagagtggaagca
gcttggaaattgtcacagtgggatttggtggaaaactatttggcagcagatgggaaatct
acaacatggagtgtcagactgggacagctattattatcagccaaaaaaagagataccaca
gctttttatgacacactgaaactagtgagagcagaacaaattgtacctctttcagctgca
agcttcgaaagaggctcttatcaacgaggatatgaatatattgtaagattgcacatgttg
tgtgagttggagcatagcatcaaaccactttttcaccagtcgccaggtgacagttctcaa
gaagattctctaaactgggtagctcgactagaaatgacccagaattcctacagagccaag
gagcccatcctggctctccggagagctttattaagcctcaacaaaagaccagattacaat
gaaatggttggagaatgctggctacagagtgccagagtagctagaaaagctggtcaccac
cagacagcctataatgctctccttaatgctggagaatcacggcttgctgaactgtatgtg
gaaagggcaaagtggctgtggtccaagggtgatgttcatcaggcactaattgttcttcag
aagggtgttgaattatgttttcctgaaaataaaaccccaactgagagtaagaacatgtta
atccatggtcgagctatgctactagtgggccgatttatggaggaaacagctaactttgag
agcaatgcagttatgaaaaaatataaggatgtgaccttgttcctgccagagtgggaggat
gggcatttttaccttgccaagtattatgacaaattgatgcccatggtcacagacaacaaa
atggaaaagcagggtgatctcattcggtatatagttcttcattttggcagatctctacaa
tatggaaaccaattcatatatcagtcaatgccacgaatgttatcactatggcttgatttt
ggtgctaaggcatatgaatgggaaaaagctggccgttctgatcgtgtacaaatgagaaat
gatttagctaaaataaataaggttatcacagagcacacaaatcacttagcaccatatcag
tttttgactgctttttcgcagttgatttcccgaatttgtcattctcatgatgaagttttt
gttgtcttgatggaaattatagccaaagtgttcctggcctatcctcaacaagcaatgtgg
atgatgacagctgtgtcaaagtcttcttatcccatgcgtgtgaacagatgcaaggaaatc
ctaaataaagctattcatatgaaaaaatccttagaaaaatttattggagatgcaactcgc
ctaacagataaacttttggaattgtgcaataaaccggtggatggaagtagttccacatta
agcatgagcactcattttaaaatgcttaaaaagctggtagaagaaccaacatttagtgaa
atcctcattcctttacaatctgtcatgatacctactcttccatcaattccgggtgcccat
gctaaccatgacccatttcctgggcattgggcctatattgcaagctttgatgatacggtg
gaaattcttgcttctcttcagaaaccaaagaagatctctttgaaaggatcagatggaaag
ttctacatcatgatgtgtaagccaaaagatgacctgagaaaggattgtagactaatggaa
ttcaattccttgattaataagtgcttaagaaaagatgcagaatctcgtagaagagaactt
catatccgaacatatgcagttattcccctgaatgatgaatgtggtattattgaatgggtt
aacaacactgctggcttgagacctattctgaccaaactatataaggaaaagggagtttat
atgacaggaaaagaacttcgccagtgtatgctgccaaaatccgcagctttgtctgaaaaa
ctcaaagtattccgagaatttcttctacccaggcatcctcctgtttttcacgagtggttt
ctgaggacattccctgatcctacatcatggtacagtagcagatcagcatactgtcgttcc
accgcagttatgtcaatggttggttatatcctggggcttggagaccgtcatggtgaaaac
attctctttgattctttgactggtgaatgtgtacatgtggatttcaactgtctcttcaat
aagggagaaacctttgaagttccagaaattgttccatttcgactgactcataatatggtt
aatggaatgggtcctatgggaacagaaggtctttttcgaagggcttgtgaagttacaatg
aggctgatgcgagatcagagagagcctttaatgagtgtcttaaaaacttttctacatgat
cctcttgtggaatggagtaaaccagtgaaagggcattccaaagcaccactgaatgaaacc
ggggaggttgtcaatgaaaaggccaagacccatgttcttgacattgagcagcgactgcaa
ggtgtaatcaagacccgaaatagagtgacagggctgccgttatctatcgaaggacatgtg
cattaccttatacaagaagctactgatgaaaacttactgtgccaaatgtaccttggttgg
accccatatatgtga
DBGET
integrated database retrieval system
