Ursus arctos (brown bear): 113256986
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Entry
113256986 CDS
T05909
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
KO
K04851
voltage-dependent calcium channel L type alpha-1D
Organism
uah
Ursus arctos (brown bear)
Pathway
uah04010
MAPK signaling pathway
uah04020
Calcium signaling pathway
uah04022
cGMP-PKG signaling pathway
uah04024
cAMP signaling pathway
uah04218
Cellular senescence
uah04260
Cardiac muscle contraction
uah04261
Adrenergic signaling in cardiomyocytes
uah04270
Vascular smooth muscle contraction
uah04530
Tight junction
uah04713
Circadian entrainment
uah04723
Retrograde endocannabinoid signaling
uah04724
Glutamatergic synapse
uah04725
Cholinergic synapse
uah04726
Serotonergic synapse
uah04727
GABAergic synapse
uah04728
Dopaminergic synapse
uah04911
Insulin secretion
uah04912
GnRH signaling pathway
uah04921
Oxytocin signaling pathway
uah04924
Renin secretion
uah04925
Aldosterone synthesis and secretion
uah04927
Cortisol synthesis and secretion
uah04929
GnRH secretion
uah04930
Type II diabetes mellitus
uah04934
Cushing syndrome
uah04935
Growth hormone synthesis, secretion and action
uah04973
Carbohydrate digestion and absorption
uah05010
Alzheimer disease
uah05020
Prion disease
uah05022
Pathways of neurodegeneration - multiple diseases
uah05031
Amphetamine addiction
uah05207
Chemical carcinogenesis - receptor activation
uah05410
Hypertrophic cardiomyopathy
uah05412
Arrhythmogenic right ventricular cardiomyopathy
uah05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
113256986 (CACNA1D)
04020 Calcium signaling pathway
113256986 (CACNA1D)
04024 cAMP signaling pathway
113256986 (CACNA1D)
04022 cGMP-PKG signaling pathway
113256986 (CACNA1D)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
113256986 (CACNA1D)
09144 Cellular community - eukaryotes
04530 Tight junction
113256986 (CACNA1D)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
113256986 (CACNA1D)
04929 GnRH secretion
113256986 (CACNA1D)
04912 GnRH signaling pathway
113256986 (CACNA1D)
04921 Oxytocin signaling pathway
113256986 (CACNA1D)
04935 Growth hormone synthesis, secretion and action
113256986 (CACNA1D)
04924 Renin secretion
113256986 (CACNA1D)
04925 Aldosterone synthesis and secretion
113256986 (CACNA1D)
04927 Cortisol synthesis and secretion
113256986 (CACNA1D)
09153 Circulatory system
04260 Cardiac muscle contraction
113256986 (CACNA1D)
04261 Adrenergic signaling in cardiomyocytes
113256986 (CACNA1D)
04270 Vascular smooth muscle contraction
113256986 (CACNA1D)
09154 Digestive system
04973 Carbohydrate digestion and absorption
113256986 (CACNA1D)
09156 Nervous system
04724 Glutamatergic synapse
113256986 (CACNA1D)
04727 GABAergic synapse
113256986 (CACNA1D)
04725 Cholinergic synapse
113256986 (CACNA1D)
04728 Dopaminergic synapse
113256986 (CACNA1D)
04726 Serotonergic synapse
113256986 (CACNA1D)
04723 Retrograde endocannabinoid signaling
113256986 (CACNA1D)
09159 Environmental adaptation
04713 Circadian entrainment
113256986 (CACNA1D)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
113256986 (CACNA1D)
09164 Neurodegenerative disease
05010 Alzheimer disease
113256986 (CACNA1D)
05020 Prion disease
113256986 (CACNA1D)
05022 Pathways of neurodegeneration - multiple diseases
113256986 (CACNA1D)
09165 Substance dependence
05031 Amphetamine addiction
113256986 (CACNA1D)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
113256986 (CACNA1D)
05412 Arrhythmogenic right ventricular cardiomyopathy
113256986 (CACNA1D)
05414 Dilated cardiomyopathy
113256986 (CACNA1D)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
113256986 (CACNA1D)
04934 Cushing syndrome
113256986 (CACNA1D)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
uah04040
]
113256986 (CACNA1D)
Ion channels [BR:
uah04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
113256986 (CACNA1D)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
CAC1F_C
Ca_chan_IQ
GPHH
PKD_channel
Motif
Other DBs
NCBI-GeneID:
113256986
NCBI-ProteinID:
XP_057167779
LinkDB
All DBs
Position
Unknown
AA seq
2137 aa
AA seq
DB search
MMMMMMMKNMHHQRQQQADHANEANYARGTTLPLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADTDILAEEDPAPCAFSGNGRQCAANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEESKRNTSMPTSETESVNTENVS
GGGENQGGCGSLCQAISKSKLSRRWRRWNRFNRRRCRAAVKSVTFYWLVIVLVFLNTLTI
SSEHYDQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIT
ETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLF
IIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGG
PSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKIARK
ESLENKRNTKPEVNQIANSDNKVTIDDYREEDEDKDPYPPCDVPVGEEEEEEEEDEPEVP
AGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSS
AALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMATFGAFLHKGAFCRNYFNLLDM
LVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMI
VTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFILYKDGDVDNPVVRERIWQNS
DFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSSGENVGPVYNYRVEISIFFIIYIIIVA
FFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWY
VVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFK
PKGYFSDAWNTFDSLIVIGSIIDVALSEADNSEESNRISITFFRLFRVMRLVKLLSRGEG
IRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQA
VLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGEEHTCGSNFAIVYFISFYMLCAFLI
INLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPP
LGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRA
VIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKN
TTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEETKREEEEDVFKRNGALLGNHVNHVNS
DRRDPLQQTNTTHRPLHVQRPSVPPASDTERPLFPPAGNSGCHSHHNHNSIGKQAPSSTN
ANLNNANMSKAAPGKRPSIGNLEHMSENGHHSSHKHDREPQRRSSIKRSDSGDEQCPTIC
REDPEIHGYFRDSRCLEEQEYFSGEEGYEDAGSPTWGRQNYSYYSRYPGGSWDFEWPRGY
HHPQGFLEDEDSPVCYDSRRSPRRRLLPPTPTSHRRSSFNFECLRRQSSQEEVPPSPALP
HRTALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPPYRDWTPCYAPLIQVE
RPDALDQVNGSLPSLHRSSWYTDEPGISYRTFTPASLTVPSSFRNKNSDKQRSADSLVEA
VLISEGLGRYARDPKFVSATKHEIADACDLTIDEMESAASNLLNGTVHPRANGGVGPVSH
RQDYELQDFGPGYSDEEPDPGRDEEDLADEMICITTL
NT seq
6414 nt
NT seq
+upstream
nt +downstream
nt
atgatgatgatgatgatgatgaaaaacatgcaccatcaacggcagcagcaagcggaccac
gcgaacgaggcaaactatgcaagaggcaccacactccctctttctggtgaaggaccaact
tctcagccgaatagctccaagcaaaccgtcctgtcttggcaagctgcaatcgatgctgcc
aggcaggccaaggctgcccaaactatgagcacctctgcacccccacctgtgggatctctc
tcccaaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtccaacagc
cgacctgcccgcgcccttttctgtttgtcactcaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagatt
atagcgtatggattattgctacatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattctggaacaattaaccaaagaa
acagaaggcggtaaccactccagtggcaagtcaggaggcttcgatgtcaaagccctccgc
gcctttcgggtgttacgaccacttcgactagtgtcaggagtgcccagtttacaagttgtc
ctgaactccattataaaagccatggttcccctccttcacatagcccttttggtattattt
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaaca
tgtttttttgctgacacagatatcctagctgaagaggacccagcgccgtgtgcgttctca
gggaacggacgccagtgtgccgccaacggcacggagtgcaggagtggctgggttggccca
aacggaggcatcaccaacttcgataactttgcctttgccatgctcaccgtgtttcagtgc
atcaccatggagggctggacagacgtgctctactggatgaatgatgctatgggatttgaa
ttgccctgggtgtattttgtcagtctcgtcatctttgggtcatttttcgtactaaatctt
gtacttggtgtattgagcggagaattctcaaaggaaagagagaaggctaaagcccgggga
gacttccagaagctccgggagaagcagcagctggaggaggacctaaagggctacttggat
tggatcacccaagccgaagacattgatcctgagaatgaggaagaaggcggagaggaaagc
aaacgaaacaccagcatgcccaccagcgagacggagtcggtgaacacagagaacgtaagt
ggcggaggcgagaaccaaggcggctgtgggagtctctgccaagccatttccaaatccaag
ctcagccgacgctggcggcgctggaaccgcttcaatcgcagaagatgtcgggctgctgtg
aagtctgtcacgttttactggctggttatcgtcctggtgtttctcaacaccctaaccatt
tcctctgagcattatgaccagcctgactggctgacgcagattcaagatatcgctaacaaa
gtcctcctggctctgttcacctgcgagatgctggtaaaaatgtacagcttgggtctccag
gcgtatttcgtctctctctttaaccggtttgattgcttcgtggtgtgcggtggaattacc
gagaccatcttggtggagctggaaatcatgtctcccctggggatctctgtgtttcggtgt
gtgcgcctcttaaggattttcaaggtgaccaggcactggacttccctgagcaacttagtg
gcctccttgttaaactccatgaagtccatcgcttcgctgttgcttctgctttttctcttc
atcatcatcttttccctgcttgggatgcagctgttcggtggcaagtttaattttgacgaa
acgcagaccaagcggagcacctttgacaatttccctcaagcccttctgacagtattccag
atcctgacaggggaagactggaacgccgtgatgtatgacggcattatggcctacggcggc
ccgtcctcttcggggatgatcgtctgtatctacttcatcatcctcttcatttgtggtaac
tatatcctgctgaatgtcttcttggccatcgctgtagacaatctggctgacgcggaaagt
ttgaataccgcccagaaagaggaagctgaagagaaggagaggaaaaagattgccagaaaa
gagagcctggagaataaaaggaacacgaaaccagaagtcaaccagatagccaacagcgac
aataaggttacaattgatgactatcgagaagaggatgaagacaaggacccctaccctcct
tgtgatgtgccagtaggggaagaggaagaggaggaggaagaggacgaacctgaggttcct
gctggcccccgtcctcgcagaatctcagagttgaacatgaaggagaaaatcgcccctatt
cctgaagggagtgcgttcttcattctgagcaagaccaacccgatccgcgtgggctgccac
aagctcatcaaccaccacatcttcaccaacctcatcctcgtcttcatcatgctgagtagc
gccgcccttgccgccgaggaccccatccgcagccactccttccggaacactatactgggt
tactttgactatgctttcacagccatctttactgttgaaatcctgttaaagatggcgacg
tttggagctttcctccacaaaggggctttctgcaggaattacttcaatctgctggatatg
ctggttgttggggtgtccctggtatcatttgggatccaatccagtgccatctccgttgtc
aagattctgagggtcttaagggtcctgcggccactcagggcgatcaacagagcgaaagga
cttaagcacgtggtccagtgcgtcttcgtggccatccggaccatcggcaacatcatgatc
gtcaccacccttctccagttcatgttcgcctgcatcggggtccagttgttcaagggaaag
ttctatcgctgtacagacgaagccaaaagtaaccccgaagagtgcagggggcttttcatc
ctctacaaggatggggatgttgataaccctgtggtccgtgagaggatctggcaaaatagc
gatttcaacttcgacaacgtcctgtctgctatgatggcgctgttcacggtctccacgttt
gagggctggcctgcgttgctgtataaagccatcgactcgagcggagagaacgtgggccct
gtctacaactaccgagtggagatctccatcttcttcatcatctacatcatcatcgtggct
ttcttcatgatgaacatctttgtgggctttgtcatcgtcacgtttcaggagcagggagag
aaagagtataagaactgtgagctggacaaaaatcagcgccagtgtgttgaatatgccttg
aaagcacgtcccctgcggagatacattcccaaaaacccctaccagtacaagttctggtac
gtggtgaactcctcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactc
tgcttggccatgcagcactacgagcagtccaagatgttcaacgacgccatggacattctg
aacatggtcttcactggggtgttcaccgtcgagatggttttgaaagtcatcgcgttcaaa
cctaaggggtattttagtgacgcctggaacacgtttgactccctcatcgtaatcggcagc
attatagacgtggccctcagcgaagccgacaactctgaagagagcaatagaatctccatc
acctttttccgtcttttccgagtgatgcggttggtgaagcttctcagcaggggggaaggc
atccggacattgctgtggacttttataaagtcctttcaggcactgccctatgttgccctc
ctcatagccatgctgttcttcatctatgcggtgattggcatgcagatgtttgggaaggtt
gctatgagagataacaaccagatcaacaggaacaacaatttccagacctttccccaggcg
gtgctgctgctcttcaggtgtgccacgggcgaagcctggcaggagatcatgctggcctgc
ctgccggggaagctctgcgaccccgagtcggactacaaccccggggaggagcacacgtgt
gggagcaacttcgccattgtttatttcatcagtttctacatgctctgcgcgtttctgatc
atcaacctgtttgtggctgtcatcatggacaactttgattatctgacccgggactggtct
attctggggcctcaccatttagatgaattcaaaagaatatggtcggaatacgaccctgag
gcaaaaggaaggatcaagcacctcgatgtggtcactctgctccgccgcatccagcctccc
ctggggtttgggaaattatgcccacacagagtagcctgtaagagactcgtggccatgaac
atgcctctcaacagcgatgggacggtcatgtttaatgcaaccctgtttgctttggttcga
acagctcttaaaatcaagacggaagggaacctggaacaagctaatgaagaactccgagct
gtgatcaagaaaatctggaagaaaaccagcatgaagctgcttgaccaagttgtccctcca
gccggtgatgatgaggtaaccgtggggaagttctatgccactttcctgatacaggactac
tttaggaaattcaagaaacggaaagaacaaggcctggtgggaaaataccctgcgaagaac
accaccattgccctacaggcaggattaaggacactgcatgacattgggccagaaatccgg
cgtgctatatcatgtgatttgcaagatgacgagccggaggaaacaaaacgagaagaagaa
gaagatgtattcaaaagaaatggtgccctgcttggaaaccatgtcaatcatgttaatagt
gataggagagacccccttcagcagaccaataccacccaccgtcccctgcatgtccaaagg
ccttcagttccacctgcaagtgatactgagagaccgctgtttcctccagcaggaaattcg
gggtgtcatagccatcataaccataattccataggaaagcaagctcccagctcaacaaat
gccaatctcaataatgccaatatgtccaaagctgcccctggaaagcggcccagcattggg
aaccttgagcatatgtctgaaaatgggcatcactcctcccacaagcacgaccgggagcct
caaagaaggtccagtattaaaagatctgactcgggggacgagcagtgccccaccatctgc
cgggaagatccagagatccatggctacttcagggactcccgctgcttggaggagcaggaa
tatttcagtggcgaggagggctatgaggatgccggctcaccgacctggggcaggcaaaac
tacagctactacagccgatacccaggcggcagctgggacttcgagtggccccgaggctac
catcacccccaaggcttcttggaggatgaggactcgcccgtttgctatgattcccggaga
tctccaaggagacgcctactacctcccaccccgacatcccaccggagatcctccttcaac
ttcgagtgcctgcggcggcagagcagccaggaggaggtcccgccgtcccctgccctcccc
caccgcacagccctgcctctgcacctgatgcagcaacagatcatggcagttgcgggcctg
gattccagtaaagcccagaagtactcgccgagccactcgacccggtcatgggccacccct
ccggcgacccctccgtaccgggactggacgccatgctacgcacccctgatccaggtggag
cggccggatgccctggaccaggtcaacggcagcctgccatccctgcaccggagctcatgg
tacacggacgagcccggcatctcataccgaacgttcacaccagccagcctgactgtcccc
agcagcttccgcaacaagaacagtgacaagcagaggagcgcagacagcttggtggaggcg
gtcctgatatctgaaggcttaggacggtatgcaagggaccccaaatttgtgtcggcaaca
aaacacgaaatcgccgatgcttgtgacctgaccatcgacgagatggaaagtgcagccagc
aacctgctcaacgggaccgtgcatccgcgggctaacgggggcgtgggccccgtctcccat
cggcaggactatgagctccaggacttcgggccgggctacagcgatgaagagcccgacccc
ggaagagatgaggaggacctggcagacgaaatgatctgcatcaccaccctgtag
DBGET
integrated database retrieval system
