Ursus arctos horribilis (North American brown bear): 113257022
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Entry
113257022 CDS
T05909
Symbol
PDHB
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit beta, mitochondrial
KO
K00162
pyruvate dehydrogenase E1 component subunit beta [EC:
1.2.4.1
]
Organism
uah
Ursus arctos horribilis (North American brown bear)
Pathway
uah00010
Glycolysis / Gluconeogenesis
uah00020
Citrate cycle (TCA cycle)
uah00620
Pyruvate metabolism
uah00785
Lipoic acid metabolism
uah01100
Metabolic pathways
uah01200
Carbon metabolism
uah01210
2-Oxocarboxylic acid metabolism
uah04066
HIF-1 signaling pathway
uah04922
Glucagon signaling pathway
uah05230
Central carbon metabolism in cancer
uah05415
Diabetic cardiomyopathy
Module
uah_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
113257022 (PDHB)
00020 Citrate cycle (TCA cycle)
113257022 (PDHB)
00620 Pyruvate metabolism
113257022 (PDHB)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
113257022 (PDHB)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
113257022 (PDHB)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
113257022 (PDHB)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
113257022 (PDHB)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
113257022 (PDHB)
Enzymes [BR:
uah01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
113257022 (PDHB)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Transket_pyr
Transketolase_C
Motif
Other DBs
NCBI-GeneID:
113257022
NCBI-ProteinID:
XP_026356907
LinkDB
All DBs
Position
Unknown
AA seq
359 aa
AA seq
DB search
MAAASGLMRRPLEQVSGLLRRRFHRTAPAALQVTVREAINQGMDEELERDEKVFLLGEEV
AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
DQVINSAAKTYYMSGGLQPVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNS
EDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPSEAQSKDFLIPIGKAKIERQGTHITVV
AHSRPVGHCLEAATVLSKEGIECEVINMRTIRPMDIETIEASVMKTNHLITVEGGWPQFG
VGAEVCARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTLNI
NT seq
1080 nt
NT seq
+upstream
nt +downstream
nt
atggcggcagcgtctggcctgatgcggagaccccttgaacaggtctccgggctgctgagg
aggcgcttccaccggacggcaccggcggcactgcaggtgacagttcgtgaggctataaac
caaggtatggatgaggagctggaaagagatgagaaggtatttctgcttggggaagaagtt
gcccagtatgatggggcatataaggtcagtcgaggcctgtggaagaaatatggagataag
aggatcatagacactcccatatctgagatgggctttgctggaattgccgtgggtgcagct
atggctgggttgaggcccatttgtgaatttatgaccttcaatttctctatgcaagccatt
gaccaggttataaactcagctgccaagacctactacatgtcggggggccttcagcctgtg
cccatagtcttcagggggcccaatggcgcctcagcaggtgtagctgcccagcactcacag
tgcttcgctgcctggtatgggcactgcccaggcttaaaggtggtcagcccctggaattca
gaggatgcaaaaggacttattaaatcagccattcgggataataatccagtggtggtgcta
gagaatgaactgatgtatggggttccttttgaatttccttcagaagctcagtcaaaagat
tttctgattcccattggaaaagccaaaatagaaaggcaagggacacacatcaccgtagtt
gcccattcaagacccgtgggccactgcttagaagctgcaacagtgttatccaaagaggga
attgaatgtgaggtgataaatatgcgaaccatcagaccaatggacattgaaacaatagaa
gccagtgtcatgaagaccaatcatctcataactgtggaaggaggctggccacagtttgga
gtaggagctgaagtttgtgccaggatcatggaaggcccagcattcaatttcctggatgct
cctgcagttcgtgtcactggggctgacgtccctatgccttatgcaaagatcctagaagac
aactctatacctcaggttaaagacatcatatttgcaataaagaaaacattaaatatttag
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