KEGG   Ursus arctos (brown bear): 113257162
Entry
113257162         CDS       T05909                                 
Symbol
VHL
Name
(RefSeq) von Hippel-Lindau disease tumor suppressor
  KO
K03871  von Hippel-Lindau disease tumor supressor
Organism
uah  Ursus arctos (brown bear)
Pathway
uah04066  HIF-1 signaling pathway
uah04120  Ubiquitin mediated proteolysis
uah05200  Pathways in cancer
uah05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:uah00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    113257162 (VHL)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    113257162 (VHL)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    113257162 (VHL)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    113257162 (VHL)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:uah04121]
    113257162 (VHL)
Ubiquitin system [BR:uah04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul2 complex
    Target recognizing subunit
     113257162 (VHL)
SSDB
Motif
Pfam: VHL VHL_C Arm_vescicular
Other DBs
NCBI-GeneID: 113257162
NCBI-ProteinID: XP_026357138
LinkDB
Position
Unknown
AA seq 219 aa
MPRKAGNVEEAEASAEEVGAEEVGPEEYGGEESGAEESGPEESDPEEPRAEEEMEAGQPR
PVLRSVNSCEPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRGHLWLFR
DAGTYDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDI
VRSLYEDLEDHPNVRKDLERLTQEHIENQRLEGETEDFN
NT seq 660 nt   +upstreamnt  +downstreamnt
atgccccggaaggcagggaacgtggaagaggccgaggcgagtgcggaggaggtgggcgcc
gaggaggtgggccctgaagagtacggcggggaggagtcgggcgctgaggagtccgggccg
gaagagtctgacccagaggagccgcgcgctgaggaggagatggaggccgggcagccgcgg
ccggtgctgcgctcagtgaactcctgtgagccgtcccaggtcatcttctgcaaccgcagc
ccgcgcgtcgtgctgccggtgtggctcaacttcgacggcgagccgcagccctacccgacg
ctgccgccgggcacgggccgccgcatccacagctaccgaggtcacctttggctcttccga
gatgcagggacatacgatgggcttctggttaaccagaccgagctgtttgtgccgtctctc
aatgttgatggacagcctatttttgccaacatcacactgccagtgtatactctgaaagag
cggtgcctccaggttgtccgaagcctagtgaagcctgagaattacaggagactggacatc
gtgagatcactctatgaagatctggaagaccacccgaatgtaaggaaagacctggagcgg
ctgacacaggagcatattgaaaatcaacggctggaaggggagactgaggattttaattga

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