Ursus arctos (brown bear): 113257877
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Entry
113257877 CDS
T05909
Symbol
LRP6
Name
(RefSeq) low-density lipoprotein receptor-related protein 6 isoform X1
KO
K03068
low density lipoprotein receptor-related protein 5/6
Organism
uah
Ursus arctos (brown bear)
Pathway
uah04150
mTOR signaling pathway
uah04310
Wnt signaling pathway
uah04928
Parathyroid hormone synthesis, secretion and action
uah05010
Alzheimer disease
uah05022
Pathways of neurodegeneration - multiple diseases
uah05200
Pathways in cancer
uah05224
Breast cancer
uah05225
Hepatocellular carcinoma
uah05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
113257877 (LRP6)
04150 mTOR signaling pathway
113257877 (LRP6)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
113257877 (LRP6)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113257877 (LRP6)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
113257877 (LRP6)
05226 Gastric cancer
113257877 (LRP6)
05224 Breast cancer
113257877 (LRP6)
09164 Neurodegenerative disease
05010 Alzheimer disease
113257877 (LRP6)
05022 Pathways of neurodegeneration - multiple diseases
113257877 (LRP6)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
uah04131
]
113257877 (LRP6)
Membrane trafficking [BR:
uah04131
]
Endocytosis
Clathrin-mediated endocytosis
Low-density lipoprotein receptor (LDLR) family proteins
113257877 (LRP6)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ldl_recept_b
FXa_inhibition
Ldl_recept_a
Vgb_lyase
DUF5050
SGL
EGF_LRP2
cEGF
EGF
Motif
Other DBs
NCBI-GeneID:
113257877
NCBI-ProteinID:
XP_026358192
LinkDB
All DBs
Position
Unknown
AA seq
1613 aa
AA seq
DB search
MGAVLRSLLACSFCALLRAAPLLLYANRRDLRLVDATNGKENATIVVGGLEDAAAVDFVF
GHGLIYWSDVSEEAIKRTEFNKTESVQNVVVSGLLSPDGLACDWLGEKLYWTDSETNRIE
VSNLDGSLRKVLFWQELDQPRAIALDPSSGFMYWTDWGEVPKIERAGMDGSSRFIIINTE
IYWPNGLTLDYEEQKLYWADAKLNFIHKSNLDGTNRQAVVKGSLPHPFALTLFEDTLYWT
DWNTHSILACNKYTGEGLREIHSNIFSPMDIHAFSQQRQPNATNPCGIDNGGCSHLCLMS
PVKPFYQCACPTGVKLLENGKTCKDGATELLLLARRTDLRRISLDTPDFTDIVLQLEDIR
HAIAIDYDPVEGYIYWTDDEVRAIRRSFIDGSGSQFVVTAQIAHPDGIAVDWVARNLYWT
DTGTDRIEVTRLNGTMRKILISEDLEEPRAIVLDPMVGYMYWTDWGEIPKIERAALDGSD
RVVLVNTSLGWPNGLALDYDEGKIYWGDAKTDKIEVMNTDGTGRRVLVEDKIPHIFGFTL
LGDYVYWTDWQRRSIERVHKRSAEREIIIDQLPDLMGLKATNVHRIIGSNPCAEENGGCS
HLCLYRPQGLRCACPIGFELISDMKTCIVPEAFLLFSRRADIRRISLETNNNNVAIPLTG
VKEASALDFDVTDNRIYWTDISLKTISRAFMNGSALEHVVEFGLDYPEGMAVDWLGKNLY
WADTGTNRIEVSKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEWGGKPKIDRAAMDG
SERTTLVPNVGRANGLTIDYAKRRLYWTDLDTNLIESSNMLGLNREVIADDLPHPFGLTQ
YQDYIYWTDWSRRSIERANKTSGQNRTIIQGHLDYVMDILVFHSSRQAGWNECASSNGHC
SHLCLAVPVGGFVCGCPAHYSLNADNRTCSAPTTFLLFSQKSAINRMVIDEQQSPDIILP
IHSLRNVRAIDYDPLDKQLYWIDSRQNMIRKAQEDGSQGFTVVVNSVPNQNLEIQPYDLS
IDIYSRYIYWTCEATNVINVTRLDGRSIGVVLKGEQDRPRAIVVNPEKGYMYFTNLQERS
PKIERAALDGTEREVLFFSGLSKPIALALDSRLGKLFWADSDLRRIESSDLSGANRIVLE
DSNILQPVGLTVFENWLYWIDKQQQMIEKIDMTGREGRTKVQARIAQLSDIHAVKELNLQ
EYRQHPCAQDNGGCSHICLVKGDGTTRCSCPMHLVLLQDELSCGEPPTCSPQQFTCFTGE
IDCIPVAWRCDGFTECEDHSDELNCPVCSESQFQCASGQCIDGALRCNGDANCQDKSDEK
NCEVLCLIDQFRCSNGQCIGKHKKCDHNVDCSDKSDELDCYPTEEPAPQATNTVGSVIGV
IVTIFVSGTIYFICQRMLCPRMKGDGETMTNDYVVHGPASVPLGYVPHPSSLSGSLPGMS
RGKSMISSLSIMGGSSGPPYDRAHVTGASSSSSSSTKGTYFPAILNPPPSPATERSHYTM
EFGYSSNSPSTHRSYSYRPYSYRHFAPPTTPCSTDVCDSDYAPSRRMTSVATAKGYTSDL
NYDSEPVPPPPTPRSQYLSAEENYESCPPSPYTERSYSHHLYPPPPSPCTDSS
NT seq
4842 nt
NT seq
+upstream
nt +downstream
nt
atgggggccgtcctgaggagcctcctggcctgcagtttctgtgcgctcctgagagcggcc
cctttgttgctttatgcaaacagacgggacttgcgattggttgatgctacaaatggcaaa
gagaatgctacgattgtagttggaggcttggaggatgcagctgcggtggactttgtgttt
ggtcatggcttgatatactggagtgatgtcagcgaagaagccattaaacgaacagagttt
aacaaaactgagagtgtacagaatgttgttgtctctggattattgtcccctgatgggctg
gcatgtgattggcttggagaaaaattatactggacagattctgaaacaaatcggattgaa
gtttctaatttagatggatctttacggaaagttttattttggcaagaattggatcaaccc
agagctattgccttagatccttcaagtgggttcatgtactggacagactggggagaagta
ccaaagatagaacgtgctggaatggatggttcaagtcgattcattataataaacactgaa
atttactggccaaatggactgactttggattatgaggaacagaagctttattgggcagat
gcaaaactcaatttcatccacaaatcaaatctggatggaacaaatcggcaggcagtggtt
aaaggttctcttccacatccttttgccttgacattatttgaggacacattgtactggact
gactggaatacacactctattttggcttgcaacaagtacactggcgagggtctgcgtgaa
atccattctaacatcttctctcccatggatatacatgccttcagccaacagaggcagcca
aatgctacaaatccatgtggaattgataatggtggttgttcccacttgtgtttgatgtct
ccagtcaaacctttttatcagtgtgcttgcccaactggggtcaaactcctggagaatgga
aaaacctgcaaagatggtgccactgaattactgcttttagcacgaaggacagacttgaga
cgcatttctttggatacaccagatttcacagacattgttttacagttagaagacatccgt
catgccattgccatagattatgatcctgtggaaggctatatctactggactgacgatgaa
gtgagggccatacgccgctcattcatagatggatctggcagtcagtttgtggtcactgct
caaattgcgcatcctgatggtattgctgttgactgggttgcccgaaatctttattggaca
gacactggcactgatcggatagaagtgacaaggctcaatgggaccatgaggaagatcttg
atttcagaggacttagaggaaccccgagccattgtgttagatcccatggttgggtacatg
tattggactgactggggagaaatcccgaaaattgagcgagcagctctggatggttctgac
cgagtagtgttggttaacacttctcttggttggccgaatggtttagccttggattatgat
gaaggcaaaatatactggggagatgccaaaacagacaaaattgaggttatgaatactgat
ggcactgggagacgagtactagtggaagacaaaattcctcacatatttgggtttactttg
ttgggtgactatgtttactggactgactggcagagacgtagcatcgaaagagtacacaaa
cgaagcgcagagagggaaatcatcatagatcagcttcctgacctcatgggcctaaaggcc
acaaatgttcatcgaatcattggttccaacccctgcgctgaggaaaatgggggatgtagc
catctttgcctctataggcctcagggcctccgctgtgcctgccccattggctttgaactc
atcagtgacatgaagacctgcattgtcccagaggctttccttttgttttcacggagagca
gatatcaggcgaatttctttggaaactaacaataataatgtggccattcctctcactggt
gtcaaagaagcttctgctttggattttgatgtaacggacaaccgcatttactggactgat
atatcactcaagaccatcagcagagcctttatgaatggcagtgcgctggaacacgtggta
gaattcggcttagattatccagaaggcatggcagtagactggctggggaagaacttgtac
tgggcagacacaggaacgaatcgaattgaggtgtcaaagttggatgggcagcaccgacaa
gttttggtgtggaaagacttagatagtcccagagctcttgcactggaccctgctgaagga
tttatgtattggactgaatggggtggaaaacctaagatagaccgagctgccatggatgga
agtgaacgtactacattagttccaaatgtgggacgggcaaatggcttaactattgattat
gctaaaaggaggctttattggacagacctggacaccaacttaatagaatcttcaaatatg
cttggactcaaccgtgaagttatagcagatgacttgcctcatccttttggcttaactcag
taccaagattacatctactggacggactggagccgacgcagcattgaacgtgccaacaaa
accagtggccaaaaccgcaccatcattcagggccatttggattatgtgatggacatcctc
gtctttcactcctctcggcaggcggggtggaatgagtgtgcttccagcaatgggcactgc
tcccacctctgcttggctgtgccagttggaggttttgtttgtggatgccctgcccactac
tcacttaatgctgacaacaggacttgtagtgctccaactactttcctgctcttcagtcaa
aagagtgccatcaaccgcatggtgattgatgagcagcagagccctgacatcatccttcct
atccacagccttcggaatgtccgggccattgactatgacccactggacaagcaactctat
tggattgactcacgacaaaacatgatccgaaaagcacaagaagacggcagccagggcttt
actgttgttgtgaactcagttccaaatcagaacctagaaatacaaccctatgacctcagc
attgatatttatagccgctacatttactggacttgtgaggccaccaatgtcattaatgta
acaagattagatgggagatcaattggagtggtactaaaaggcgagcaagacagacctcga
gccattgtggtgaacccggagaaggggtatatgtattttaccaatcttcaggaaaggtct
cccaaaattgaacgggccgctttggatggaacagaacgggaggttctctttttcagtggc
ttaagtaaaccaattgcgttagcccttgatagcagattgggcaagctcttttgggcagat
tcagacctccggcgaattgaaagcagtgatctctcaggtgccaaccggatagtattagaa
gactccaatatcttgcagcctgtgggactgactgtgtttgaaaactggctatattggatt
gataagcagcagcaaatgattgaaaaaattgacatgacaggccgagagggtagaaccaaa
gtccaggctcgaattgcccagcttagtgacattcatgcagtgaaagagctgaaccttcag
gaatatagacagcacccttgtgctcaggataatggtggctgttcacatatttgtcttgta
aaaggagatggtactacaaggtgctcttgccccatgcacttggttctgcttcaagacgag
ctatcatgtggagaacccccaacatgttctcctcagcagtttacttgtttcacgggagaa
attgactgtatccctgtggcttggcgctgcgacgggtttactgaatgcgaagaccacagt
gacgaactcaattgtcctgtatgctcagagtcccagttccagtgtgccagtgggcagtgt
attgatggtgccctccgatgcaatggagatgcaaactgccaggataaatcagatgagaag
aactgtgaagtgctttgtttaattgatcagttccgctgttccaacggtcagtgcattgga
aaacataagaaatgtgatcataatgtggactgcagtgacaagtcagatgaactggattgt
tatccaactgaggaaccagctccacaggccaccaacacagttggttccgttattggagta
attgtcaccatttttgtgtctggaaccatatactttatctgccagagaatgttgtgtcca
cgtatgaagggggatggggaaaccatgactaatgactatgtcgttcatggaccagcttct
gtgccccttggttatgtgccacatccaagttctttgtcaggatctcttccaggaatgtct
cgaggtaaatcaatgatcagctccctaagtatcatggggggaagcagtggacccccttac
gaccgagctcatgtcacaggagcatcatcgagtagttcttcaagcaccaaaggcacttac
ttccctgcaattttgaaccctccaccatccccagccacagagcgatcacattacactatg
gaatttggttattcttcgaatagcccttccactcataggtcctacagctacaggccgtac
agctaccggcactttgcaccccctaccacaccctgcagcacagatgtttgtgacagtgac
tatgctcccagccggagaatgacctcagtggcaacagccaagggctacactagtgacttg
aactatgactcagagcctgtgcccccacctcccacaccccgaagccaatacctgtcagca
gaagagaactatgaaagctgcccaccttctccatacacagagaggagctactctcatcac
ctctacccaccaccgccctctccctgtacagactcctcctga
DBGET
integrated database retrieval system
