Ursus arctos (brown bear): 113259105
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Entry
113259105 CDS
T05909
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1 isoform X1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah00760
Nicotinate and nicotinamide metabolism
uah01100
Metabolic pathways
uah04068
FoxO signaling pathway
uah04148
Efferocytosis
uah04152
AMPK signaling pathway
uah04211
Longevity regulating pathway
uah04213
Longevity regulating pathway - multiple species
uah04218
Cellular senescence
uah04310
Wnt signaling pathway
uah04922
Glucagon signaling pathway
uah04936
Alcoholic liver disease
uah05031
Amphetamine addiction
uah05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
113259105 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
113259105 (SIRT1)
04068 FoxO signaling pathway
113259105 (SIRT1)
04152 AMPK signaling pathway
113259105 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
113259105 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
113259105 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
113259105 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
113259105 (SIRT1)
04213 Longevity regulating pathway - multiple species
113259105 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
113259105 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
113259105 (SIRT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
113259105 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
uah03036
]
113259105 (SIRT1)
03029 Mitochondrial biogenesis [BR:
uah03029
]
113259105 (SIRT1)
Enzymes [BR:
uah01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
113259105 (SIRT1)
Chromosome and associated proteins [BR:
uah03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
113259105 (SIRT1)
Mitochondrial biogenesis [BR:
uah03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
113259105 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SIR2
DUF592
Motif
Other DBs
NCBI-GeneID:
113259105
NCBI-ProteinID:
XP_026360103
LinkDB
All DBs
Position
Unknown
AA seq
744 aa
AA seq
DB search
MADEAALALQPGGSPSAVAAEREAASPPAGEPLRKRPRRDCPGLGRSPGEPGGAAPEREV
PAATGGCPAAAAALWREAAAAGGEREAQAPTAGEGDKGPGLQGLSREPPPADDFDDDDDD
DDEGEEEEEAAAAAIGYRDDLLFDDEIITNGFHSCESDEDDRASHASSSDWTPRPRIGPY
TFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIED
AVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAIDFPDLPDPQAMFDIEYFRKD
PRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGS
FATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRA
MKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVI
INELCHRLGGEYAKLCCNPVKLSEISEKPPRTQKELAHLSELPPTPLNISEDSSSPERTS
PPDSSVIVTLLDQAPKSNVDDPGVSKSKDCMEEKSQEGQNSTRNIESVTEQLESPDLKNV
GSNTGEKNERTSVADTVRKCWPARLAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSDSED
DVLSSSSCGSNSDSGTCQSPSVEEHLEDESEIEEFYNGLEDEADVNERAGGTGFGIGGGD
HEAGSEAISMKQEVTDINYPSNKS
NT seq
2235 nt
NT seq
+upstream
nt +downstream
nt
atggcggacgaggcggcgctcgcccttcagcctggcggctccccctcggcggtggcggcc
gagagagaggccgcgtcgccgcccgccggggagccactccgcaagaggccgcggagagac
tgtcccggcctggggcggagcccgggcgagcccggtggggcggcccctgagcgtgaggtg
ccagcggcgaccgggggctgccccgcggcggccgcggcgctgtggcgggaggcggcggcg
gcgggcggggagcgggaggcccaggcgccgacggccggagaaggagacaaagggccgggc
ctacagggcctatcccgggagccgccgccggccgacgacttcgacgacgacgacgacgac
gacgacgagggcgaagaggaggaagaggcggcggcggcggcgattgggtaccgagatgac
cttctgtttgatgatgaaataatcaccaatggttttcattcctgtgaaagtgatgaggat
gatagagcctcacatgcaagctctagtgactggactccaaggccacggataggtccatat
acttttgttcagcaacatctcatgattggcacagatcctcgaacaattcttaaagattta
ctaccagaaacaattcctccacctgaattggatgatatgacactgtggcagattgttatt
aatatcctttcagaaccaccaaaaaggaaaaaaagaaaagatattaatacaattgaagat
gctgtgaaattactgcaagagtgcaaaaaaataatagttctaactggagctggggtttct
gtttcttgtggaatacctgacttcaggtcaagagatggtatttatgctcgccttgcgata
gactttccagaccttccagatcctcaagcaatgtttgatattgaatatttcagaaaagat
ccaagaccattcttcaagtttgcaaaggaaatatatcctggacagttccaaccatctctc
tgtcacaaattcatagccttgtcagataaagaaggaaaactacttcggaactatactcag
aacatagatacactggaacaggttgcaggaatccaaaggataattcaatgtcatggttcc
tttgcaacagcatcttgcctgatttgtaaatacaaagtagactgtgaagctgtacgagga
gatatttttaatcaggtggttcctcgttgtcctaggtgcccagctgatgagccacttgct
atcatgaaaccagagatagtcttttttggtgaaaatttaccagagcagtttcatagagcc
atgaagtatgacaaagatgaagttgatctcctcattgttattgggtcttccctgaaagta
agaccagtagcactaattccaagttccataccccatgaagtgcctcagatattaataaat
agagaacctttgcctcatctgcattttgatgtagagcttcttggagactgtgatgtcata
ataaatgaattatgccataggttaggtggtgaatatgccaaactttgctgcaaccctgta
aagctttcagaaattagtgaaaaacctccacgaacacaaaaagagttggctcatttgtca
gagttgccacccacacctcttaatatttcagaagactcaagttcaccggaaagaacttca
ccacctgattcttcagtgattgttacacttttagaccaagcacctaagagtaatgttgat
gatcctggtgtgtccaaatcaaaagattgtatggaagaaaagtcacaggaaggacagaat
tctactaggaacattgaaagtgttactgaacagttggaaagtccggatttgaagaatgtt
ggctctaacactggggagaaaaatgaaagaacttcagttgctgacacagtgaggaagtgc
tggccagctagacttgcaaaggagcaaattagcaaacggcttgatggtaaccagtatctg
ttcttaccaccaaatcgttatattttccatggcgctgaggtatattcggactctgaagat
gacgtcttatcctctagttcttgtggtagtaacagtgatagtggaacgtgccagagtcca
agtgtagaagaacacttggaggatgaaagtgagattgaagaattttacaatggtttggaa
gatgaagctgatgttaatgagagagctggaggaactggatttggaattggtggaggtgat
catgaggcaggcagtgaagctatatccatgaaacaggaagtaacagacattaactatcca
tcaaacaaatcataa
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