Ursus arctos (brown bear): 113259637
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Entry
113259637 CDS
T05909
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah00230
Purine metabolism
uah01100
Metabolic pathways
uah04024
cAMP signaling pathway
uah05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
113259637 (PDE10A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
113259637 (PDE10A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
113259637 (PDE10A)
Enzymes [BR:
uah01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
113259637 (PDE10A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
113259637 (PDE10A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD
DUF7334
Motif
Other DBs
NCBI-GeneID:
113259637
NCBI-ProteinID:
XP_026360970
LinkDB
All DBs
Position
Unknown
AA seq
1061 aa
AA seq
DB search
MASPVEPLAPRPQAPLPAAGDELGSGPGKLRPEPWGGAAGGGSAVGPGPAPERPGRGRAE
RAAPPSPPPSPAGRASPAGGPGAQCARGSGGWGSVRAPFALALSSSVPSSSPSSFYFWPP
PPPPPPSLLPSSSAFHLPVRLPGREGAAAAAAPRGGGGDAGGGGGGGQEAAPLSVPPSSS
PRGGGGSGGGRRRLFFCSALQGLLLPARAGLRLPLGPAARRAGSPGFPGAGGGCPGPSPG
GGGRTPRRPRGAGFALAAASPLLFGSDMEDGPSNNASCFRRLTECFLSPSLTDEKVKAYL
SLHPQVLDEFVSESVSAETVEKWLKRKNNKPEDESAPKEVSRYQDTNMQGVVYELNSYIE
QRLDTGGDNQLLLYELSSIIKIATKADGFALYFLGECNNSLCVFTPPGIKEGKPRLIPAG
PIAQGTTISAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGDLIGI
LELYRHWGKEAFCMSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDN
IVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPIFKKTKEIR
FSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQ
MVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTA
EEWQGLMHFNLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFDLEKLCRFIM
SVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHGLFTDLERKGLLIACLCHDLDHRGFSNS
YLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIAT
DLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIY
AEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQIFPPTEPLLQ
ACRNNLSQWEKVIRGEESAVWISSQPGAHGPSEKLPVKIDD
NT seq
3186 nt
NT seq
+upstream
nt +downstream
nt
atggccagccccgtagagccgctcgctccccgcccccaggcccccctgccagcggccggg
gacgagctcggatccggtcccggcaaactccgcccggagccctggggcggcgctgccggc
ggggggagcgcggtgggcccgggtccggcccccgagcggcctggccgcggccgggccgag
cgcgccgcgcccccgagcccgcccccctcccccgcaggccgcgccagccccgcggggggc
ccgggcgcccagtgtgcgcgcggcagcggcggctggggttcggtccgcgctcccttcgcg
ctcgccctctcctcctctgtcccctcctcctctccatcttccttttacttctggccgccg
ccccccccgccccctccttctcttctcccctcctcatctgcctttcacctccccgtgcgt
ctcccaggaagggagggcgcagcggcggcggcggcgcctcgaggaggcggcggcgatgct
ggcggcggcggcggaggaggacaagaggcagctcccttgagcgtccctcccagcagtagt
ccccgcggcggcggtggcagcggcggcgggcggcggcggctcttcttctgctctgcgctc
cagggtttgctgctcccagcccgcgccgggctccggctcccgctcggcccggccgcccgc
cgcgcgggctcccccggcttcccgggtgccggcgggggctgccccggccccagcccaggc
ggcggcggccgaactccgcggcggcccagaggcgccggcttcgccctcgccgccgcgtcc
cccctgctcttcggctccgacatggaagatggaccttctaataatgcgagctgcttccga
aggttgacggagtgtttcctaagccccagtttgacagatgaaaaagtgaaggcatatctt
tctcttcatccccaggtgttagacgagtttgtatctgaaagtgttagtgcagagactgta
gaaaaatggctgaagaggaaaaacaacaaaccagaagatgaatcggctcctaaggaagtc
agcaggtaccaagacacgaatatgcagggagttgtatatgaactaaacagctacatagaa
cagcggttggatacaggaggagacaaccagctactcctctatgaattgagtagcatcatt
aaaatagccacaaaagctgatggatttgcactgtatttccttggagagtgcaataatagt
ctgtgcgtgttcactccacctggaatcaaggaaggaaaaccccggctcatccctgctggg
cccattgctcagggcaccaccatctctgcctacgtggccaagtccagaaaaacgttgcta
gtggaagacatccttggggatgaacgatttccaagaggtactggactggagtcagggact
cgcatccagtctgttctttgtttaccgatcgtcactgcaattggtgatttgattggtatc
ctcgagctgtatcggcactggggcaaagaagccttctgtatgagtcatcaggaggttgca
acagcaaatcttgcctgggcttcagtagcaatacatcaggtgcaggtatgcagaggcctt
gctaaacagactgaattgaatgacttcctacttgatgtatcaaagacatatttcgataac
atagttgcaatagactctctacttgaacacataatgatatatgcaaaaaatctggtgaat
gccgatcgttgtgcacttttccaggtagaccataagaataaggagttatattcagacctt
tttgatattggagaggaaaaggaaggaaaacctatcttcaagaagaccaaagaaataaga
ttttcaattgagaaaggaatcgccggtcaggtagcaagaacaggggaagtcctgaacatt
ccagatgcctatgcagacccacgctttaacagagaggtggacttgtacacgggctacacc
acccggaatatcctgtgcatgcccatcgtgagccgaggcagcgtgatcggggtggtgcag
atggttaacaaaataagcggcagtgccttctcgaaaacggacgaaaacaacttcaaaatg
ttcgccgtcttttgtgctctcgccttacactgtgccaatatgtatcacagaatccgtcat
tctgagtgcatttaccgggtgacgatggagaagctgtcctaccatagcatttgtacggcg
gaggagtggcagggcctcatgcacttcaacctccccgtgcgcctctgcaaggaaatcgaa
ttattccactttgacattggtccttttgaaaacatgtggcctggaatttttgtgtacatg
gtccatcggtcctgtgggacatcctgctttgatcttgaaaagttgtgtcgtttcattatg
tctgtgaagaaaaactatcggcgggttccttatcacaactggaaacacgccgtcactgtg
gcacactgcatgtacgccattctccagaacaaccacgggctcttcaccgaccttgagcgc
aaaggactgctaatcgcgtgtctgtgtcacgacctggaccaccggggcttcagtaacagc
tacctgcagaaattcgatcaccctctggcagctctctactccacttcgaccatggagcag
catcacttctctcagaccgtgtccatccttcagttggaagggcacaatatcttctccacc
ctgagctccagtgagtacgaacaggtgcttgagatcatccgcaaagccatcattgccaca
gaccttgctttatactttggaaacaggaaacagttggaagagatgtaccagactggatcg
ctaaaccttaataatcaatcacatagagatcgtgtcattggtttgatgatgactgcctgt
gatctttgttctgtaacaaaactatggcctgttacaaaattgacggcaaatgatatatat
gcagagttctgggctgagggcgatgagatgaagaagttgggaatacagcctattcccatg
atggacagagacaagaaggatgaggtcccgcaaggccagctgggcttctacaacgccgtg
gccatcccctgctacaccaccctcacccagatcttcccgcccacagagcctctcctccaa
gcgtgcaggaataacctcagccagtgggagaaggtgatccgaggggaggagagcgcggtg
tggatctcatcccagccaggggcccacgggccctccgagaagctgcctgtgaagatcgat
gactga
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