Ursus arctos (brown bear): 113259947
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Entry
113259947 CDS
T05909
Symbol
ARHGEF12
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
KO
K07532
Rho guanine nucleotide exchange factor 12
Organism
uah
Ursus arctos (brown bear)
Pathway
uah04270
Vascular smooth muscle contraction
uah04360
Axon guidance
uah04611
Platelet activation
uah04625
C-type lectin receptor signaling pathway
uah04810
Regulation of actin cytoskeleton
uah05135
Yersinia infection
uah05152
Tuberculosis
uah05163
Human cytomegalovirus infection
uah05200
Pathways in cancer
uah05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
113259947 (ARHGEF12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
113259947 (ARHGEF12)
04625 C-type lectin receptor signaling pathway
113259947 (ARHGEF12)
09153 Circulatory system
04270 Vascular smooth muscle contraction
113259947 (ARHGEF12)
09158 Development and regeneration
04360 Axon guidance
113259947 (ARHGEF12)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113259947 (ARHGEF12)
05205 Proteoglycans in cancer
113259947 (ARHGEF12)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
113259947 (ARHGEF12)
09171 Infectious disease: bacterial
05135 Yersinia infection
113259947 (ARHGEF12)
05152 Tuberculosis
113259947 (ARHGEF12)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
uah04131
]
113259947 (ARHGEF12)
Membrane trafficking [BR:
uah04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
113259947 (ARHGEF12)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PDZ
PDZ_6
PDZ_2
PH_13
SOS1_NGEF_PH
Pept_S41_N_bact
COS
AAA_23
Motif
Other DBs
NCBI-GeneID:
113259947
NCBI-ProteinID:
XP_026361334
LinkDB
All DBs
Position
Unknown
AA seq
1543 aa
AA seq
DB search
MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERSASHDFDPTDSSSKKTKSSSEE
SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT
LVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPG
ASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQ
EAKKHIPQLQEQLSKATGSAQDGAAVTSSKPLGDALTVSEVEADPSDGLSRIDSSSGDAS
RPSSDSADSPKSALKERIYLEENPEKSEVIQDTDTQSLIGSPSPRIAPHIIGAEDDDFGT
EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKQTNSKETRR
VFLEFHQFFLDRSAHLKVSVPDEISVDLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHL
EDFRQKRSMGLTLAESELTKLDAERDKDRVTLEKERACAEQIVAKIEEVLMTAQAVEEDK
SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDREGEEKGKRRGFPSI
LGPPRRPSRHDNSAIGRAMELQKQRHPKHLSTPSSVSPEPQDPAKLRQSGLAGEGTDVGY
LPANSMSSVASGATLSQEGGKENDTGSKQLGETPASGDCVDGTPRTPNTVFDFPPPPLDQ
VQEEEWEVERVTEHGTPKPFRKFDSIAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG
LKPSEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ
LHIGLNEQMKSVRKRNETSVIDQIGEDLLTWFSGPGEDKLKHAAATFCSNQPFALEMIKS
RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKV
KKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSNLKLSEYPNVEELRNLDLTKRKM
IHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI
KLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSAK
PIPLPQSPPCEGDNDEEAAPKLKVGHHSISVPGLQSPDRDLGLESPLMSSKPQSHSLGTS
GKSEVDDLFVAERQFAKEQHADGTLQEAGASYQIPIPDPHLPASEERWALDALRNLGLLK
QLLVQQLGLTEKSTQEDWPHFPRYRTASSGVQTNGGAQNSENSKACPPGEGQMPFRTGIG
DIATCYSPRTSAESSAPRDSVVLAFQDSQASNILVMDHMVMTPEMPPAEPEGSLDESGEH
FFDAREAHSDDNPSEGDGAVRKEEDVTLRISGNYLILDGYEAVQESSTDEDVASSLPPPP
PAGIPSTDSARPHQHSPQRAHSDGAASPFTPEFLLQQRWGAMEDSCFEIQSPPSCADSQS
QIMEYIRKIEADLEHLKKVEESYSMLCQRLAGSALTDKHSDKS
NT seq
4632 nt
NT seq
+upstream
nt +downstream
nt
atgagtggcacacagtctactatcaccgacaggtttcccctcaaaaaacctataaggcat
gggagtattttgaaccgagagtcaccaacagataagaagcagaaagttgagcgcagtgca
tcacatgattttgatcctacagatagctcctccaagaagacaaagtctagttcagaggag
agtagatccgagatatatggtcttgttcagcgttgcgtgatcatccagaaggatgacaat
ggatttgggctgacggtcagtggagacaatccagtcttcgtacagtctgtcaaagaagat
ggagcagccatgcgggctggggtacagacaggtgatcgaatcatcaaggtgaatggaact
ctggtgactcattcaaaccatttggaagtggtgaagctaatcaaatctggttcctatgta
gctctcactgttcagggacgcccacctgggtcgccccagattccactcgccgattctgaa
gtagagccatcagtcattggacatatgtctcccatcatgacatcccctcattcacctgga
gcatctgggaacatggagagaattactagtcctgtgctcatgggggaggaaaacaatgtg
gttcataaccagaaagtagaaattctgagaaaaatgttacagaaagaacaggaacggcta
cagttattgcaggaagattacaaccgaacacctgcccaaagattgctaaaagagatccaa
gaggccaagaaacacattcctcagctgcaagagcagttatccaaagccacgggctctgct
caggatggagctgcagttacatcctccaagcctttaggtgacgcactgacagtcagtgag
gtggaagctgatcctagtgatggactaagcagaattgactctagcagtggagacgcttct
cggcccagtagtgacagcgcagacagtcccaagagtgccctgaaagagaggatttatcta
gaggaaaacccagagaaaagcgaagtgattcaggacactgatactcagtcactcattggg
agtccctctccccgtatagcacctcatattattggagcagaggatgatgatttcggtact
gaacatgaacagatcaatgggcagtgcagctgtttccagagcatcgagctgctgaaatct
cgccctgctcacctggctgttttcttacaccacgtggtctcacagtttgaccccgcgacg
ctgctctgttatctctattcagacctgtacaagcagaccaattccaaggagactcgtcgt
gtcttccttgagtttcatcagttcttcctggatcgatctgcacacctgaaagtttctgtg
cctgatgaaatatcagtagatctagaaaaaagaagacctgagcttatacccgaggatctg
caccgccactatatccaaactatgcaggaaagagtccacccagaagttcagaggcacttg
gaagattttcggcagaagcgtagcatggggctgaccttggctgaaagcgaactgactaaa
cttgacgcagagcgagacaaggaccgggtcactttggagaaggaacgggcatgtgcagaa
cagatcgttgccaaaattgaagaagtgttgatgactgctcaggctgtagaagaagataag
agttcaacaatgcagtatgttatccttatgtacatgaagcatttgggggtaaaagtgaaa
gaacctcgaaatttggagcacaagcggggtcggattggattccttccaaaaatcaagcag
agtatgaagaaagatcgagaaggcgaagaaaaagggaagcgcagaggattccccagcatc
ctgggacccccaaggagaccaagccgtcatgacaatagtgcaattggcagggccatggag
ctacagaaacagcggcacccaaagcacttatccacaccctcttccgtgagtcctgagcct
caggaccctgctaagttgcgccagagtgggttagcaggtgaaggaacggacgtcggatac
ctgccagccaattccatgtcctctgtggcttcaggggccactctttcccaggaaggaggg
aaagagaatgatacaggatcaaagcaacttggagaaacaccagcatctggagactgcgta
gatggcacccctcggactccgaatactgtctttgatttcccacctcctcctttagaccaa
gtgcaggaggaggaatgggaagtggaaagggtgactgaacatgggacaccaaagcccttt
cgaaagtttgacagcatagcttttggagaaagtcaaagtgaggatgaacagtttgaaaat
gacttagagacagacccaccgaactggcaacagctcgttagtcgagaagtgttactggga
ctaaagccttctgagatcaaaagacaggaagtaattaatgaattgttctacactgaaaga
gctcatgttcgaacactgaaagttcttgatcaagtattctatcagcgagtgtccagagaa
ggaattctgtcaccttcagaactacggaaaattttttcaaacttggaagatattcttcaa
cttcatattggattgaatgagcaaatgaagtctgttcgaaagaggaatgagacctcagtt
attgatcagattggggaagatttgctgacctggttcagtggaccaggagaggacaagttg
aagcacgctgctgctaccttttgcagtaaccagcctttcgccctggaaatgatcaagtct
cgtcagaaaaaggattctcgattccagacctttgtgcaagatgctgagagtaatcctctg
tgtcgtcgtctgcagctgaaggatatcattcctacccaaatgcagaggcttaccaagtac
cctcttctgttggataatattgccaaatacacagaatggccaacggaaagggagaaggtg
aagaaagctgcagatcactgtcgtcagatcttgaattatgtaaatcaggctgtcaaggag
gcagaaaataaacagcgtttagaagactatcagcgtcgtctggatacctccaatctgaag
ttgtcagagtacccaaacgtggaagagctcaggaatttggatttaacaaaaaggaagatg
attcatgaagggccattggtctggaaggtgaaccgagataaaactattgatctatacacg
ttgctgctggaagacattcttgtattgttacaaaagcaggatgacagactggtgttaaga
tgtcatagtaagattctggcgtctaccgctgacagcaaacacacatttagccctgtcatt
aagttgagtacagtgttggttcgacaagtggcaacagataacaaagctttatttgtcatc
tctatgtcagacaatggagcccaaatttatgaactggtggcacagacagtttccgaaaag
actgtctggcaagacctaatctgtcggatggccgcatccgtgaaggaacaatccgcaaag
cccatcccgttgccacagtcaccaccttgcgaaggagacaacgatgaagaagcagctcca
aagttaaaggtgggacaccacagcatttcggtccctggtctgcagagtccagacagagat
ttgggattagagtctcccttaatgtcgtcaaaacctcagtctcattcactggggacctct
gggaaatccgaggtagatgatctgtttgtggccgagaggcagtttgctaaggagcagcat
gcagatgggactctgcaggaagccggagcaagttatcagatcccaatcccagacccacac
ttgcctgcctcggaagaacggtgggcactggatgcactgaggaatttgggcttgctgaag
cagttgcttgtccaacagctgggtttgactgagaagagcactcaggaagactggccacat
ttcccaagatacaggacagcgtcttcaggggtgcagacaaacggtggagcccagaactct
gagaatagtaaggcctgtcctcctggtgaaggacagatgccctttagaactggaattggt
gacattgcaacttgttacagtccacggacttcagctgaatcttcggctccgcgggattca
gtggtactggcattccaagatagccaggcaagtaacattttagtaatggaccacatggtt
atgaccccagagatgcctcctgcggagccagaagggagtctcgatgagagtggagagcac
ttttttgatgcccgtgaagcacacagtgatgataacccatcagaaggtgatggagcggtt
cggaaggaagaggatgttactttgcgcatctcaggaaactatctgattcttgacggctat
gaagcggtgcaggagagctccacggatgaggacgttgcttcctcgctccccccgccgccc
ccggcaggcatcccctccacagactctgcccgcccgcaccagcactcgccccagcgtgcc
cattccgacggggcggcttcaccgttcacccccgaattcctgctccagcagcgctggggg
gctatggaggattcctgttttgagatccagagtcccccctcttgtgcagactctcagagc
cagatcatggagtacattcggaagatcgaggctgaccttgaacacttaaagaaggtggaa
gaaagttacagcatgctttgccaaaggctggctggatcagccctcacagacaagcactca
gataaaagttag
DBGET
integrated database retrieval system
