Ursus arctos horribilis (North American brown bear): 113260016
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Entry
113260016 CDS
T05909
Symbol
BACE1
Name
(RefSeq) beta-secretase 1 isoform X1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
uah
Ursus arctos horribilis (North American brown bear)
Pathway
uah05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
113260016 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
uah01002
]
113260016 (BACE1)
Enzymes [BR:
uah01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
113260016 (BACE1)
Peptidases and inhibitors [BR:
uah01002
]
Aspartic peptidases
Family A1: pepsin family
113260016 (BACE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
113260016
NCBI-ProteinID:
XP_026361471
LinkDB
All DBs
Position
Unknown
AA seq
505 aa
AA seq
DB search
MAQALPWLLLWMGSGVLPAHGTQPGIRLPLRSGLGAPPLGLRLPRETVEEPEEPGRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HGKRAREEGVGSVCPCSHCPAVRIPGPLSVWEVVIVASRRSHHTVKASVWTRALSVLPGV
VRPAQAVTSAGDPEKQELPQPLWKL
NT seq
1518 nt
NT seq
+upstream
nt +downstream
nt
atggcccaggcactgccctggctcctgctgtggatgggctcgggggtgctgcctgcccac
ggcacccagcctggcatccggctgcccctgcgaagcgggctgggggcgccccccctgggg
ctgcgcctgccccgggagactgtcgaggagccggaggagcccggccggaggggcagcttt
gtggagatggtggacaacctgaggggcaagtccggtcagggctactacgtggagatgacc
gtgggcagccccccgcagacgctcaacatcctggtggacacaggcagcagtaactttgca
gtgggggctgccccccaccctttcctgcatcgctactaccagaggcagctgtccagcaca
taccgggacctccggaagggcgtgtatgtgccctacacccagggcaagtgggagggggag
ctgggcaccgacctggtgagcatcccccacggccccaacgtcactgtgcgtgccaacatc
gccgccatcactgaatcagacaagttcttcatcaatggctccaactgggagggcatcctg
gggctggcctatgctgagatcgccaggcccgatgactccctggagccgttcttcgactcc
ctggtaaagcagacccacgttcccaacctcttctccctgcagctctgtggcgctggcttc
cccctcaaccagtcagaagtgctggcctcagttggagggagcatgatcatcgggggtatc
gaccactcactgtacacgggcagcctctggtatacacccatccggcgggagtggtactac
gaggtcatcattgtgcgggtggagatcaacgggcaggacctgaaaatggactgcaaggag
tacaactacgacaagagcatcgtggacagtggcaccaccaaccttcgtttgcccaagaaa
gtgttcgaagctgccgtcaaatccatcaaggcagcctcctcgacggagaagttcccggac
gggttctggctgggggagcagctggtgtgctggcaggcaggcaccaccccttggaacatt
ttcccggtcatctccctctacctaatgggcgaggtcaccaatcagtctttccgcatcacc
atccttccacagcaatacctgcggccagtggaagatgtggccacgtcccaagacgactgc
tacaagttcgccatctcacagtcctccacgggcaccgtgatgggagctgtgatcatggaa
ggcttctacgttgtctttgatcgagcccgaaaacgaattggctttgccgtcagtgcttgt
catggtaagagagccagggaggagggtgtgggctccgtctgtccgtgttctcactgtcca
gcagttaggatacccgggcccctgtcagtctgggaggtagtcatagttgcctcaaggcga
agtcaccacactgtaaaagctagtgtctggacgcgtgctttgtccgtgttgcccggcgtg
gtgaggcctgcacaggctgtaacctctgccggagacccagagaagcaagagctgcctcag
cccctatggaagctctag
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integrated database retrieval system
