KEGG   Ursus arctos (brown bear): 113260353
Entry
113260353         CDS       T05909                                 
Name
(RefSeq) phospholipid-transporting ATPase ABCA1 isoform X2
  KO
K05641  ATP-binding cassette, subfamily A (ABC1), member 1
Organism
uah  Ursus arctos (brown bear)
Pathway
uah02010  ABC transporters
uah04148  Efferocytosis
uah04975  Fat digestion and absorption
uah04979  Cholesterol metabolism
uah05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:uah00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    113260353
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    113260353
 09150 Organismal Systems
  09154 Digestive system
   04975 Fat digestion and absorption
    113260353
   04979 Cholesterol metabolism
    113260353
 09160 Human Diseases
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    113260353
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:uah02000]
    113260353
Transporters [BR:uah02000]
 ABC transporters, eukaryotic type
  ABCA (ABC1) subfamily
   ABCA1, 2, 3, 4, 7, 12, 13 subgroups
    113260353
SSDB
Motif
Pfam: ABC_tran ABC2_membrane_3 R1_ABCA1 AAA_21 DUF4162 AAA_23 Talin_IBS2B
Other DBs
NCBI-GeneID: 113260353
NCBI-ProteinID: XP_026361870
LinkDB
Position
Unknown
AA seq 2261 aa
MAYWPQLKLLLWKNLTFRRRQTCQLLLEVAWPLFIFLILISVRLSYPPYEQHECHFPNKA
MPSAGTLPWVQGIICNANNPCFRYPTPGEAPGVVGNFNKSIVSRLFSDARRLLLYSQKDT
SMKDIHQVLRTLQQIESSASSLKLQDFLVDNETFSEFLTYNLSLPRLTVDKMLGASVSLH
KVFLQGYQLHLTNLCSGSKLEEVIQLGEQEVSKLCSLPREKLDSAEQVLHSNMDILKPIL
RELNSKSPFLSKELAKATKTLLDSLGTLAQELFSMNSWSDMRQEVMFLTNVNSSSSSSQI
YQAVSRIVCGHPEGGGLKIKSLNWYEDNNYKALFGGNGTDEDAGSFYDNSTTPYCNDLMK
NLESSPLSRIIWKALKPLLVGKILYTPDTPATRQVMAEVNKTFQELAVFHDVQGMWEELS
PKIWTFMESNPEMDLVRTMLDSRSNDHFWEQQLDGLDWTAKDILAFLAKHPEDVQSANGS
VYTWREAFNETDQAIQTISRFMECVNLNKLEPVATEVRLINKSMELLDERKFWAGVVFTG
ITPGSVELPRHVKYKIRMDIDNVERTNKIKDGYWDPGPRADPFEDMRYVWGGFAYLQDVV
EQAIIRVLTGTEKKTGVYVQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKGIV
YEKEARLKETMRIMGLDNGILWFSWFISSLIPLLVSASLLVVILKLGNLLPYSDPSVVFV
FLSVFGVVTILQCFLISTLFSRANLAAACGGIIYFILYLPYVLCVAWQDYVGFSLKIFVS
LLSPVAFGFGCEYFALFEEQGIGVQWDNLFESPMEEDGFSLTTSVSMMLFDTFLYGVMTW
YIEAVFPGQYGIPRPWYFPCTKSYWFGEETDEKSHPGSSQKGVSEICMEEEPTHLKLGVS
IQNLMKVYRDGMKVAVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYIL
GKDIRFEMSTIRQNLGVCPQHNVLFDMLTVEEHIWFYARLKGLSEKHVKAEMEQMALDVG
LPPSKLKSKTSQLSGGMKRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQ
GRTIILSTHHMDEADILGDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLS
SCRNSSSTVSYLKKEDSVSQSSSDAGLGSDHESDTLTIDVSAISNLIRKHVAEARLVEDI
GHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGISETTLEEIFLKVAEESGVDAE
TSDGTLPARRNRRAFGDKQSCLRPFTEDDVIDPNDSDVDPESRETDLLSGMDGKGSYQVK
GWKLTQQQFVALLWKRLLIARRSRKGFFAQIILPAVFVCIALVFSLIVPPFGKYPSLELQ
PWMYNEQYTFVSNDAPEDLGTQELLNALTRHPGFGTRCMEGNPIPDMPCSVGEEEWTTAP
VPQTITDLFQKGNWTMENPSPTCQCSSDKIKKMLPVCPLGAGGLPPPQRKQNTADILQNL
TGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGASNSHSLPSSQEVNNAIKQVKK
HLKLAKDSSADRFLSSLGRFMTGLDTKNNVKVWFNNKGWHAISSFLNVINNAILRANLQK
GENPSQYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQER
VSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNLPVLAL
LLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVLELFTNNKLNNIN
DILKSVFLIFPHFCLGRGLIDMVKNQAMADALERFGENRFVSPLSWDLVGRNLFAMAVEG
VVFFLITVLIQYRFFIRPRPVNAKLPPLNDEDEDVKRERQRILDGGGQNDILEIKELTKI
YRRKRKPAVDRICVGIPPGECFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNKNSILSD
IHEVHQNMGYCPQFDAITELLTGREHVEFFALLRGVPEKEVGKVGEWAIRKLGLVKYGEK
YAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSIVKEGRSVVLT
SHSMEECEALCTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRIAGSNPDLKPVQEFFG
LAFPGSVLKEKHRNMLQYQLPSSLSSLARIFSILSQSKKRLHIEDYSVSQTTLDQVFVNF
AKDQSDDDHLKDLSLHKNQTVVDVAVLTSFLQDEKVKESYV
NT seq 6786 nt   +upstreamnt  +downstreamnt
atggcttactggcctcagctgaagttgttgctgtggaagaacctcactttcagaagaaga
caaacatgtcagctgttgctggaagtggcctggcctctatttattttcctgatcctgatc
tccgttcggctgagctacccaccctatgaacaacatgaatgccactttccaaacaaagcc
atgccctctgcaggaacgcttccttgggttcaggggattatctgtaatgccaataacccc
tgtttccgttatccgactcctggtgaggcccctggggttgttggaaactttaacaaatcc
attgtgtctcgcctgttctcagatgctcggcggcttctcttatatagccagaaagacacc
agcatgaaagacatacaccaagttctgaggacattacagcagatagagagttccgcttca
agcttgaagcttcaggatttcctagtggacaatgaaaccttctctgaattcctgacttac
aacctttctctgccaaggcttactgtggacaaaatgctgggggccagtgtcagtctccac
aaggtatttttgcaagggtaccagttacatttgaccaatctgtgcagtggatcaaaatta
gaagaggtgattcaacttggtgaacaagaagtttccaagctttgcagcttgccaagggag
aaactggattcagcagagcaagtgcttcattccaacatggacatcctgaaaccgatcctg
agggaactaaactctaagtctcccttcctgagcaaggaactggctaaagccacaaaaact
ttgctggatagtctcgggactttggcgcaagagctgttcagcatgaacagctggagtgac
atgcggcaggaggtcatgttcctgaccaatgtgaacagctccagctcgtccagccagata
taccaagccgtgtcgcgcatcgtctgtggccatcccgagggtgggggcctgaagatcaag
tccctcaactggtacgaggacaacaactacaaagccctctttggcggcaatggcacagat
gaagatgctggcagcttttatgacaattctacaactccttattgcaatgatttgatgaag
aatttggagtccagtcctctttcccgcatcatatggaaagctctcaagcctttgcttgtt
gggaagatcctgtatactcctgacactccagccaccaggcaggtgatggctgaggtgaat
aagacctttcaggaactggctgtgtttcatgatgtgcaaggtatgtgggaagagctcagc
cccaagatctggaccttcatggagagtaacccggaaatggaccttgttcggacaatgttg
gacagcagaagcaatgaccacttttgggaacagcaattggatggcttagactggactgct
aaagatatcctggcatttctggccaagcaccctgaggatgtccagtctgctaatggctct
gtgtacacctggagagaggccttcaatgagactgaccaggcaatccagaccatctctcgc
ttcatggagtgtgtcaacttgaacaaactcgaaccggtagcaacagaagtccggctcatc
aacaagtccatggagttgctggacgagcggaagttctgggctggtgtcgtgttcactgga
atcactcccggcagtgttgagctaccccgtcatgtcaagtacaagatccgaatggacatt
gacaatgtggagagaacaaataagatcaaggatgggtactgggacccgggtcctcgggct
gacccctttgaggatatgcggtacgtctgggggggctttgcctacttgcaagacgtggtg
gagcaggcgatcatcagggtgctgacgggcacggagaagaaaactggtgtctatgtgcag
cagatgccttacccctgttacgtcgacgacatcttcctgcgggtgatgagccggtcgatg
cccctgttcatgacgctggcctggatctactccgtggctgtgatcatcaagggcatcgtg
tatgagaaggaggcgcggctgaaggagaccatgcgcatcatgggcctggacaacggcatc
ctctggttcagctggttcatcagtagcctcattcctctgctcgtgagcgccagcctgctg
gtggtcatcctgaaattaggaaacctgctgccgtacagcgaccccagcgtagtgtttgtc
tttctgtccgtgttcggcgtggtgaccatcctgcagtgcttcctgatcagcaccctcttc
tccagagccaacctggcggcagcctgtgggggcatcatctacttcattctgtacctgccc
tatgtgctgtgcgtggcgtggcaagactacgtgggcttctctctcaagatcttcgtgagc
ctgctgtctcctgtggctttcgggtttggctgtgagtactttgcccttttcgaggagcag
ggcattggagtgcagtgggacaacctgtttgagagccccatggaggaggatggcttcagc
ctcaccacttcagtctccatgatgttgttcgacacctttctctatggagtgatgacgtgg
tacatcgaggctgtctttccaggccagtatggaatccccaggccctggtattttccttgc
accaaatcctactggtttggtgaggaaactgatgagaagagccaccctggttccagccag
aagggagtatcagaaatctgcatggaggaggaacccacacacctgaagctgggcgtgtcc
attcagaacctgatgaaggtttaccgggatggcatgaaggtggctgttgatggcctggcc
ttgaatttctatgagggccagatcacctccttcttgggccacaatggagctggaaagacc
accaccatgtcaatcctgactgggttgttccctcccacctcaggcactgcctacatcctg
gggaaagacattcgctttgagatgagcaccatccggcagaacctgggggtctgcccccag
cataacgtgctgtttgacatgctgactgtggaagaacacatctggttctatgcacgtctg
aaggggctctcggagaagcacgtgaaagcagagatggagcagatggccttggatgtgggt
ttgccacccagcaaactgaaaagcaaaacaagtcagctgtcaggtggaatgaagagaaag
ctgtctgtggctttggcctttgttgggggatccaaggttgtcattctggacgagcctact
gccggtgtggacccttactcccgcaggggaatatgggagctcctgctgaaatatcgacaa
ggccgcaccattattctgtccacgcaccacatggatgaagcggacatcctgggggacagg
attgccatcatttcccatgggaagctgtgctgtgtgggctcctccctgtttctgaagaac
cagctgggaacaggctactacctgaccctggtcaagaaggatgtggaatcctccctcagt
tcctgtagaaatagcagtagcactgtgtcgtacctgaaaaaggaggacagtgtttctcag
agcagttctgatgctggcctgggcagcgaccatgaaagtgacacgctgaccatcgatgtc
tctgccatctccaacctcatcaggaagcacgtggctgaggccaggctagtggaagacatt
gggcatgaactgacatacgtgctgccctacgaagctgccaaagagggggcctttgtggaa
ctcttccatgagattgatgaccggctctcagacctgggcatctctagttacggcatctca
gagacgaccctggaagaaatatttctcaaagtggctgaagagagtggggtggatgctgag
acctcagatggcaccttgccagcaagacgaaacagacgggccttcggggacaagcagagc
tgtcttcgcccattcactgaagatgatgtcattgatcctaatgattctgatgtagaccca
gaatccagagaaacagacctgctcagcgggatggacggcaaaggctcctaccaggtgaag
ggctggaagctcacacagcagcagtttgtggcccttctgtggaagaggctgctgattgcc
agacggagtcggaagggattctttgctcagatcatcctgccagctgtgtttgtttgcatt
gccctggtgttcagcttgatcgtgcccccctttggcaagtaccccagcctggaacttcag
ccctggatgtacaatgaacagtacacgtttgtcagtaatgatgctcctgaggacttgggc
acccaggaactcttgaatgccctcaccagacaccctggcttcgggacccgatgtatggaa
ggaaatccaatcccagacatgccctgctcagtgggggaggaggagtggaccaccgcccca
gttccccagaccatcacggacctcttccaaaaaggaaactggacaatggagaacccctca
cccacctgccagtgtagcagtgacaaaatcaagaagatgctgcccgtgtgtcccctaggg
gcaggggggctgcctcctccacaaagaaaacagaacactgcagacatccttcagaacctg
accggaagaaacatttcagattatctggtgaagacctatgtgcagatcatagccaaaagt
ttaaagaacaagatctgggtgaatgagtttaggtatggagggttttccctgggtgccagt
aattctcattcacttccttcaagtcaagaagttaataatgccatcaagcaagtgaagaag
cacttgaagctggccaaggacagttctgcagatcgatttctcagcagcttgggaaggttc
atgacaggactggacacaaaaaataacgtcaaggtgtggttcaacaacaagggctggcat
gccattagctctttcttgaatgtcatcaacaacgccattctccgggccaacctgcagaag
ggagagaaccccagccagtatgggattactgccttcaatcaccccctgaatctcaccaag
cagcagctctcggaagtggctctgatgaccacatcagtggatgtcctcgtgtccatctgt
gtcatcttcgcgatgtccttcgtcccggccagctttgttgtgttcctgatccaagagcgg
gtcagcaaagcaaagcacctgcagttcatcagtggagtgaagcctgtcatctactggctc
tccaattttgtgtgggatatgtgcaactacgtggtccctgccacgctggtcattatcatc
ttcatctgcttccagcagaagtcctacgtgtcctctaccaacctgcctgtgctagccctt
ctacttctgctgtacgggtggtcgatcacaccgctcatgtacccagcctctttcgtgttc
aagatccccagcacagcctacgtggttctcaccagcgtgaacctcttcatcgggatcaac
ggcagtgtggccacttttgtgctggagctctttaccaacaacaagctgaataacatcaat
gatatcctgaaatctgtattcttgatcttcccacatttttgcctgggacgggggctcatt
gacatggtgaaaaaccaagcaatggctgatgccttggaaaggtttggggagaaccgtttc
gtttcgccactgtcttgggacttagtgggacgaaacctcttcgccatggccgtggaaggg
gtggtgttcttccttatcactgttctcatccagtacagattcttcatcaggcccagaccc
gtaaatgcaaagcttcctcctctgaatgatgaggatgaagatgtgaagcgggaaagacag
agaattcttgatggtggaggacagaatgacatcttggaaatcaaggagctgacgaagata
tatagaagaaagaggaagcctgctgttgacaggatttgcgtgggcattcctcctggcgag
tgctttgggcttctgggagttaatggggctgggaaatcatcaactttcaagatgttaact
ggagataccactgttaccagaggagatgctttccttaacaaaaatagtatcttgtcagac
atccacgaagtccatcagaacatgggctattgccctcagttcgatgccatcacagagctg
ctgaccggaagagagcacgtggagttctttgccctcttgagaggagtcccagaaaaagaa
gttggcaaggttggtgaatgggcaattcggaaactgggcctcgtaaagtatggagaaaaa
tatgctggtaactatagcggaggcaacaagcgcaagctctcaacggccatggctctgatt
ggcgggccccctgtagtgtttctggatgaacctaccacaggcatggaccccaaagcccgg
cgattcttgtggaattgtgccctaagtattgtcaaggaaggcagatcagtagtgcttaca
tctcacagtatggaagaatgtgaagctctttgcactaggatggcaattatggtcaatggg
aggttcaggtgtcttggcagtgtccaacatctgaaaaatagatttggggatggttataca
atcgtggtacgaatagcagggtccaaccctgacctgaagcctgtgcaggagttctttgga
cttgcctttccaggcagtgtcctcaaggagaagcaccggaacatgctacagtaccagctt
ccatcctcactgtcctctctggccaggatattcagcatcctttcccagagcaagaagaga
ctccacatagaagactactctgtttctcagacaacacttgaccaagtatttgtaaacttc
gccaaggaccaaagtgatgatgaccacttaaaggacttgtcattacacaaaaaccagaca
gtagtcgatgttgcagttctcacatcttttctccaggatgagaaagtgaaagaaagttat
gtatga

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