Ursus arctos (brown bear): 113262493
Help
Entry
113262493 CDS
T05909
Symbol
PDGFRA
Name
(RefSeq) platelet-derived growth factor receptor alpha isoform X1
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah01521
EGFR tyrosine kinase inhibitor resistance
uah04010
MAPK signaling pathway
uah04014
Ras signaling pathway
uah04015
Rap1 signaling pathway
uah04020
Calcium signaling pathway
uah04072
Phospholipase D signaling pathway
uah04144
Endocytosis
uah04151
PI3K-Akt signaling pathway
uah04510
Focal adhesion
uah04540
Gap junction
uah04630
JAK-STAT signaling pathway
uah04810
Regulation of actin cytoskeleton
uah05163
Human cytomegalovirus infection
uah05200
Pathways in cancer
uah05206
MicroRNAs in cancer
uah05214
Glioma
uah05215
Prostate cancer
uah05218
Melanoma
uah05230
Central carbon metabolism in cancer
uah05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
113262493 (PDGFRA)
04014 Ras signaling pathway
113262493 (PDGFRA)
04015 Rap1 signaling pathway
113262493 (PDGFRA)
04630 JAK-STAT signaling pathway
113262493 (PDGFRA)
04020 Calcium signaling pathway
113262493 (PDGFRA)
04072 Phospholipase D signaling pathway
113262493 (PDGFRA)
04151 PI3K-Akt signaling pathway
113262493 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
113262493 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
113262493 (PDGFRA)
04540 Gap junction
113262493 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
113262493 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113262493 (PDGFRA)
05206 MicroRNAs in cancer
113262493 (PDGFRA)
05230 Central carbon metabolism in cancer
113262493 (PDGFRA)
05231 Choline metabolism in cancer
113262493 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
113262493 (PDGFRA)
05218 Melanoma
113262493 (PDGFRA)
05215 Prostate cancer
113262493 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
113262493 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
113262493 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uah01001
]
113262493 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
uah04090
]
113262493 (PDGFRA)
Enzymes [BR:
uah01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
113262493 (PDGFRA)
Protein kinases [BR:
uah01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
113262493 (PDGFRA)
CD molecules [BR:
uah04090
]
Proteins
113262493 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Ig_PDGFR_d4
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR1-3_N_Ig-like
VEGFR-1-like_Ig-like
V-set
Herpes_gE
Ig_6
Kinase-like
Motif
Other DBs
NCBI-GeneID:
113262493
NCBI-ProteinID:
XP_026364667
LinkDB
All DBs
Position
Unknown
AA seq
1089 aa
AA seq
DB search
MGTSLLAFLILGSLLTGPSRVFCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYP
MSEEENPNVEIRNEENNSGLFVAVLEVVSAAAAHTGLYTCYYNHTQTEETDIEGRRIYIY
VPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLRSNDGVVHASYDSRQGFNG
TFSVGPYICEATVRGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNN
EVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLRVPEATVKDSGDYECAARQATKEVK
EMKKVTISVHEKGFIEIKPNFSPLEAVDLHEVKHFVVDVQAYPPPRISWLKDNLTLIENL
TEITTDIEKIQEIRYRSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSILDL
VDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWAILANNISNIITEVHPRD
RSTVEGRVTFTRVEETIAVRCLAKNLLGAESRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLNPADDSTRSY
VILSFENNGDYMDMKQADATQYVPMLERKEAAKYSDIQRSLYDRPASSKKKSVLDSEVKN
LLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWHSEPEKRPSFYHLSEIVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDADNAYIGVTYKNEEDKLKDWEGSLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq
3270 nt
NT seq
+upstream
nt +downstream
nt
atggggacttcccttctggccttcctgatcttaggctctctcctcacagggcccagccga
gtcttctgccagctttcattaccctccatcctgccaaacgaaaatgaaaaggtcgtgcag
ctgaattcatccttttctctgagatgctttggggagagtgaagtgagctggcagtacccc
atgtctgaagaagagaaccccaatgtggaaatcagaaacgaggagaacaacagcggcctt
tttgtggccgtgctggaggtggtcagcgcggcggcggcgcacacgggcttgtacacctgc
tattacaaccacacccagacggaggagaccgacatcgagggcaggcgtatctacatctac
gtgccagacccggatgtagccttcgtgcctctgggaatgacagattatttagtcatcgtg
gaggatgatgattctgccatcataccttgtcgcacgactgatcccgagactccggtcacc
ttgcgcagcaatgacggggtggtgcacgcctcctatgacagcagacagggcttcaatggg
accttcagcgttgggccctatatctgtgaagccaccgtcaggggaaagaagttccagacc
atcccatttaatgtttatgctttaaaagcaacgtcagaacttgatctagaaatggaagct
cttaaaactgtgtataagtcaggggagacgattgtggtcacctgcgccgtctttaacaac
gaggtggtcgaccttcagtggacttaccctggagaagtgaaaggcaaaggcatcaccatg
ctggaggaaatcaaggtcccgtccatcaaattggtgtatactctgagggtccccgaggcc
acggtgaaagatagtggagattatgaatgtgctgcccgccaggccaccaaggaggtcaaa
gagatgaagaaagtcaccatttctgtccatgagaaagggttcattgaaatcaaacccaac
ttcagcccgttggaagctgtcgacctgcatgaagtcaaacatttcgtggtggacgtgcag
gcctacccccctcccaggatatcctggctgaaggacaacctgactctgattgaaaatctc
acggagatcaccacggacatagaaaagattcaggaaataaggtatcggagcaaattaaag
ctgatccgtgctaaggaggaagacagtggccattacacgatcgtcgttcaaaatgaagat
gacgtgaagagctatactttcgaactcctaactcaagttccctcatctattctggacttg
gtggacgaccaccacggctccacggggggacagactgtgagatgcaccgccgaagggacg
cctcttcctgatatcgagtggatgatttgcaaggatattaagaagtgtaataatgaaact
tcatgggcgattttggccaacaatatctcaaacatcatcacggaggtccacccccgagac
aggagcactgtggagggccgagtgacgttcaccagagtggaggagaccatcgccgttcga
tgtctggccaagaatctccttggggccgagagccgcgagctcaagctggtggctcccacg
ctgcgctctgagctcacggtggccgctgccgtcctcgtgctgctggtgattgtcatcatc
tccctcatcgtcctggtcgtcatttggaaacagaaaccgaggtatgaaattcgctggagg
gtcattgaatccatcagcccggatggacatgaatatatttatgtggacccgatgcagctg
ccttatgactcgagatgggagtttccaagagatggactagtgcttggtcgtatcctggga
tctggcgcgtttgggaaagtggttgaaggaactgcctatggattaagccgctcccagcct
gtcatgaaggtagcagtgaagatgctgaaacccacagccagatccagtgagaaacaggct
cttatgtcggaactgaagataatgactcacctggggccgcatttaaacattgtgaacttg
ctgggagcctgtaccaagtcaggccctatttacatcatcactgagtactgcttctatggg
gatttggtcaactatttgcataagaatagggatagcttcctgagccgccacccggagaag
ccaaagaaagagctggacatttttggattgaaccctgccgacgacagcacacggagttac
gtcattttatcttttgaaaacaacggtgactacatggacatgaagcaagctgacgccacc
cagtacgtccccatgctggaaaggaaagaggctgccaagtactcagacatccagagatcg
ctgtatgatcgcccggcctcgtctaagaagaagtctgtgttagactcagaagtcaaaaac
ctcctttcggatgataactcagaaggccttactttgttggatttgttgagctttacctat
caagttgcacgaggaatggaatttttggcttcgaaaaattgtgtccaccgggacctggct
gctcgaaacgtcctcctggcgcaagggaaaatcgtgaagatctgtgacttcggcctggcc
agagacatcatgcacgattcgaactacgtgtcgaaaggcagtacctttctccctgtgaag
tggatggcccctgagagcatcttcgacaacctctacaccacactgagtgacgtctggtct
tacggcattctgctctgggagatcttttccctcggcggcacaccctaccccggcatgatg
gtggattctactttctacaataagattaagagtgggtaccggatggccaagcctgaccac
gccaccagtgaagtctacgagatcatggtgaaatgctggcacagtgagccggagaagaga
ccctccttctaccacctgagtgagattgtggagaacctgctgcccggacagtataagaag
agttacgaaaagattcacctggacttcctgaagagcgaccaccccgccgtggcgcgcatg
cgcgtggacgccgacaacgcctacattggcgtcacctacaaaaacgaggaagacaagctg
aaggactgggagggcagcctggacgagcagaggctgagcgcggacagcggctacatcatc
cccctgcccgacatcgaccctgtccctgaggaggaagacctgggcaagaggaacagacac
agctcgcagacctcagaagagagtgctatcgagacaggttcgagcagctccaccttcatc
aagagagaggacgagaccatcgaggacatcgacatgatggacgacattggcatagactcc
tcagacctggtagaggacagcttcctgtga
DBGET
integrated database retrieval system
