KEGG   Ursus arctos (brown bear): 113265351
Entry
113265351         CDS       T05909                                 
Symbol
ITGA2B
Name
(RefSeq) integrin alpha-IIb
  KO
K06476  integrin alpha 2B
Organism
uah  Ursus arctos (brown bear)
Pathway
uah04015  Rap1 signaling pathway
uah04151  PI3K-Akt signaling pathway
uah04510  Focal adhesion
uah04512  ECM-receptor interaction
uah04611  Platelet activation
uah04613  Neutrophil extracellular trap formation
uah04640  Hematopoietic cell lineage
uah04810  Regulation of actin cytoskeleton
uah04820  Cytoskeleton in muscle cells
uah05165  Human papillomavirus infection
uah05200  Pathways in cancer
uah05222  Small cell lung cancer
uah05410  Hypertrophic cardiomyopathy
uah05412  Arrhythmogenic right ventricular cardiomyopathy
uah05414  Dilated cardiomyopathy
uah05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:uah00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    113265351 (ITGA2B)
   04151 PI3K-Akt signaling pathway
    113265351 (ITGA2B)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    113265351 (ITGA2B)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    113265351 (ITGA2B)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    113265351 (ITGA2B)
   04810 Regulation of actin cytoskeleton
    113265351 (ITGA2B)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    113265351 (ITGA2B)
   04611 Platelet activation
    113265351 (ITGA2B)
   04613 Neutrophil extracellular trap formation
    113265351 (ITGA2B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    113265351 (ITGA2B)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    113265351 (ITGA2B)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    113265351 (ITGA2B)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    113265351 (ITGA2B)
   05410 Hypertrophic cardiomyopathy
    113265351 (ITGA2B)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    113265351 (ITGA2B)
   05414 Dilated cardiomyopathy
    113265351 (ITGA2B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:uah01009]
    113265351 (ITGA2B)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:uah04147]
    113265351 (ITGA2B)
   04515 Cell adhesion molecules [BR:uah04515]
    113265351 (ITGA2B)
   04090 CD molecules [BR:uah04090]
    113265351 (ITGA2B)
Protein phosphatases and associated proteins [BR:uah01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     113265351 (ITGA2B)
Exosome [BR:uah04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   113265351 (ITGA2B)
Cell adhesion molecules [BR:uah04515]
 Integrins
  Integrin alpha subunits
   113265351 (ITGA2B)
CD molecules [BR:uah04090]
 Proteins
  113265351 (ITGA2B)
SSDB
Motif
Pfam: Integrin_A_Ig_3 Integrin_A_Ig_2 Integrin_A_Ig_1 FG-GAP FG-GAP_3 Integrin_alpha
Other DBs
NCBI-GeneID: 113265351
NCBI-ProteinID: XP_026368447
LinkDB
Position
Unknown
AA seq 1037 aa
MARAVCPLHALWLLEWVQLLLGPGAIPAAWALNLDPVQLTLYTGPNGSHFGFALDFYKDN
HGRVAVVVGAPRTLGPSQEETGGVFLCPWKAEGSQCTLLPFDLNDETRHVGSHTFQTFKS
RQGLGASVVSWNDNIVACAPWQHWNALEKTEEAEKTPVGGCFVAQLQNGHRAEYSPCRAN
TMSQVYVKNGFRDDRRYCEAGFSSAVTQAGELVLGAPGGYFFLGLLARAPIASIVSSYRP
GTLLWHVPSQSFTFDYSKPEYYDGYRGYSVAVGEFDGDLNTTEYVLGAPTWSWTLGAVEI
LNSYHQTLYKLHGEQMASYFGHSVTVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVY
LFLQPRGHHVLGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDVAVAAPYGGPSGRGQV
LVFLGQSEGLSSRPSQILDSPFPAGSGFGFSLRGATDIDDNGYPDLLVGAYGANKVAVYR
AQPVVMASVQLLVQDSLNPAVKNCVLPQTQTLVSCFNIQMCVGATGHNIPQQLPLSAELQ
LDRQKPRQGRRVLLLNSQLAGTTLHLDLGGRQSPICHTTVAFLRDEADFRDKLSPIVLSF
NVSLQPRKDGVAPGLVLHGDTHVQEQTRIILDCGEDDLCVPQLQLTASVAGSPLLIGADN
VLELQMDAANEGEGAYEAELAVHLPPGAHYMRAVSNVEGFERLICNQKKENETKMVLCEL
GNPMKRNARIGITMLVSVENLEEAGEHVSFWLQTRSKNSQNPNSEAVLLDVPVRAEAHVE
LRGNSFPASLVVVAEEDNRENSSDIWGPKVEHTYELHNNGPSTISGLHLSLCLPGQSQRS
DLLYILDIEPQGGLQCSPQPTPNPDKMNWRLPTPSPSPTSPGHHKRERRQASLPGSNQPA
GLQDPILLSCNSGPHTVVQCELREMARGQRAMVRVLAFLQLPSLQQRPLDQFVLQSQAWF
NVSSLPYAVPALSLPSGETQVQTRLLRALEERDIPIWWVLVGVLGGLLLLMLLVLAMWKA
GFFKRNRPPLEEDEEED
NT seq 3114 nt   +upstreamnt  +downstreamnt
atggccagagctgtgtgtccccttcatgccctctggcttctggagtgggtgcagctgctc
ttgggacctggtgccatccctgcagcctgggccttgaacctggacccagtgcaactcacc
ttgtacacaggccccaatggcagccacttcgggtttgctctggacttctacaaggacaac
catgggagagtggccgtcgtggtgggcgccccgcggaccctgggccccagccaggaggag
acaggcggcgttttcctgtgcccctggaaggccgagggcagccagtgcaccttgctgccc
ttcgacctcaatgatgagaccagacacgtaggctcccacaccttccaaaccttcaagtcc
cgacaaggattgggggcgtcggtcgtcagctggaacgacaacattgtggcctgcgccccc
tggcagcactggaacgccctagaaaagaccgaagaggctgagaagacgcccgtaggcggc
tgcttcgtggctcagctccagaacggccaccgcgcggagtactcgccctgtcgggctaac
accatgagccaggtttacgtgaaaaatggctttagagacgaccggcgctactgcgaagcg
ggcttcagctccgcggttactcaggctggagagctggtgcttggggccccgggaggctat
tttttcttaggtctcctggcccgggctcccattgccagtatcgtctcgagttaccgccca
ggcaccctcttgtggcacgtgccctcccagagcttcaccttcgactacagcaagccagag
tactacgacggctaccgggggtactcggtggccgtgggagagttcgacggggatctcaac
actacagagtatgtcctcggtgcccccacctggagctggaccctgggagcggtggaaatt
ttgaactcgtaccaccagacgctgtacaagctgcatggagagcagatggcttcgtatttt
ggacactcggtgaccgtcactgatgtcaacggagacgggaggcacgacctgcttgtgggc
gcgccactgtacatggagagccgcgctgaccgcaaactggccgaggtggggcgcgtgtac
ttgttcctgcagcctcgaggtcaccacgtgctgggcgcccccagcctcctgctgaccggc
acacagctctacgggcggtttggctcggccatcgcgcctctgggcgacctcgatcgggat
ggctacaacgatgttgcagtggccgccccctacggaggtcccagtggtcggggccaagtg
ctggtgttcctgggtcagagtgaggggctgagctcacgcccctcccagatcctggacagc
ccctttccggcaggctccggcttcggcttctccctgcgaggtgccacagacatcgatgac
aatggatacccagacctactggtgggagcttatggggccaacaaggtggctgtgtacaga
gctcagccagtggtgatggccagtgtccagctgctggtacaagattcgctgaatcctgct
gtgaagaactgtgtcctgccccagacccagacactcgtgagctgctttaacatacagatg
tgtgtaggagccactgggcacaacattcctcagcagctgcccctaagtgccgagctgcag
ctggaccggcagaagccgcgccagggccggcgggtgctgctgctgaattcccaactggcg
ggcaccacgctgcatctggacctgggcgggaggcagagccccatctgccacaccaccgtg
gccttcctccgagacgaggccgacttccgggacaagctgagccccattgtgctcagcttc
aatgtgtccttgcagcccaggaaggatggagtagcccctggtctcgtgctgcatggagac
acgcatgtccaggagcagacgcgcatcatcctggactgtggggaagatgacctgtgtgtg
ccccagctccagctcaccgccagcgtggcaggctccccactcctcattggagccgataac
gtgctggaactgcaaatggacgcagcgaacgagggcgagggggcctacgaggccgagctg
gccgtgcacctgcccccaggcgcccactacatgcgggccgtcagcaacgtcgagggcttt
gagagactcatctgtaaccagaagaaggagaatgagaccaagatggtactgtgtgagctg
ggcaaccccatgaagaggaatgcccggataggaatcacaatgttggtgagtgtggagaac
ctagaagaggctggggagcacgtgtccttctggctgcagaccagaagcaagaacagccag
aatccaaacagcgaggctgtgctgctggatgtcccagtccgggcagaggcccacgtggag
ctgcgagggaactcctttccagcgtccctggtggtggtggccgaagaagacaacagggag
aacagctccgacatctggggccccaaagtggagcacacctatgagcttcacaacaatggc
cccagcaccataagtggcctccacctcagcctctgcctccccggccagtcccagcgttct
gacctgctctacatcctggacatagagccccagggggggcttcagtgctccccccagccc
actcctaaccccgacaagatgaactggaggctgcccacccccagcccttcccccacttct
cccggccatcacaagcgggagcgcagacaggcgtccctgccagggtccaaccagccggcc
gggcttcaggatcccattctcctgagctgcaactccgggccgcatacagtggtgcagtgt
gagctgcgggagatggcacgaggccagcgggccatggtcagggtgctggccttcctgcag
ctgcccagcctccagcagaggccactggatcagttcgtgctgcagtcgcaagcttggttc
aacgtctcctcccttccctacgctgtgcccgccctcagcctgcccagtggggaaactcag
gtgcagacgcgcctgctccgcgccttggaggagagggacattcccatctggtgggtgctg
gtaggcgtgcttggtggcctgctgttgctcatgctgctggtcctggccatgtggaaggct
ggcttcttcaagcgcaaccggccgccactagaagaagatgaggaggaggactga

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