Ursus arctos (brown bear): 113265667
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Entry
113265667 CDS
T05909
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah04140
Autophagy - animal
uah04141
Protein processing in endoplasmic reticulum
uah04210
Apoptosis
uah04932
Non-alcoholic fatty liver disease
uah05010
Alzheimer disease
uah05012
Parkinson disease
uah05014
Amyotrophic lateral sclerosis
uah05016
Huntington disease
uah05017
Spinocerebellar ataxia
uah05022
Pathways of neurodegeneration - multiple diseases
uah05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
113265667 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
113265667 (ERN1)
09143 Cell growth and death
04210 Apoptosis
113265667 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
113265667 (ERN1)
05012 Parkinson disease
113265667 (ERN1)
05014 Amyotrophic lateral sclerosis
113265667 (ERN1)
05016 Huntington disease
113265667 (ERN1)
05017 Spinocerebellar ataxia
113265667 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
113265667 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
113265667 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
113265667 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uah01001
]
113265667 (ERN1)
Enzymes [BR:
uah01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
113265667 (ERN1)
Protein kinases [BR:
uah01001
]
Serine/threonine kinases: Other
IRE family
113265667 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
PQQ_3
Motif
Other DBs
NCBI-GeneID:
113265667
NCBI-ProteinID:
XP_044245066
LinkDB
All DBs
Position
Unknown
AA seq
973 aa
AA seq
DB search
MPARLLLLALLLPGPGIFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVL
QVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQ
DIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDY
AASLPEDDGEYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLKKVMH
INVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHE
GVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKNKLNYLRNSWLLI
GHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTISQDV
EEKYEHAPAKPEAPVDSMLKDIATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQKE
LEKIQLLQQQQLPFHPPGDVAQDAELLDSSGLYSESSGTSSPSTSPRASNHSLHSSGSAS
KAGASPFLEQDDEDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPE
CFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLGLE
PITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHS
FSRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQAN
ILLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQD
VSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAM
RNKKHHYRELPAEVRETLGSLPDDFVRYFTSRFPHLLSHTYRAMEPCSHERLFQPYYFHE
PPEPRPPVTPDTL
NT seq
2922 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggctgctgctgctggcgctgctgctgcccggccccgggatttttggaagt
cccagcacagtgacacttcctgaaaccttgttgtttgtgtcaactctggatggaagtttg
catgctgtcagcaagaggacaggctcaatcaaatggactttaaaagaagatcctgttctg
caggttccaacacatgtggaagagcctgctttcctcccagatcccaatgatggcagcctg
tatacgcttgggggcaagaataatgaaggcctgacgaaacttccttttaccatcccagag
ttggtgcaggcatccccatgccgaagttcagatggaattctctacatgggtaaaaagcag
gacatttggtacgttatcgatcttctgactggggagaagcagcagactttgtcatcggcc
tttgcagacagtctctgcccatcaacctctttgctgtatcttgggcgaacagagtacacc
atcaccatgtacgacaccaaaacccgagagctccggtggaacgccacctacttcgactac
gcagcctcgctgcctgaggacgacggggaatacaagatgtcccactttgtgtccaacggc
gatgggctggtggtgaccgtggacagtgaatctggcgacgtcctgtggatccaaaactac
gcttcccccgtggtggccttttacgtctggcagcgggagggtctgaagaaggtgatgcac
atcaacgtcgctgtggagaccctgcgctacctgaccttcatgtctggggaggtgggccgc
atcaccaagtggaagtacccgttccccaaggagacggaggccaagagcaagctgacgccc
accctgtatgttgggaaatactctaccagcctgtatgcctccccctccatggttcacgag
ggggttgccgttgtgccccgaggcagtactcttcctttgctggaaggcccccagaccgat
ggagtcaccattggggacaaaggggagtgtgtgatcacgcccagcacagacctcaagttt
gaccctgggctcaaaggcaagaacaagctcaactacctgaggaactcctggcttctgata
ggacaccatgaaacccccctgtctgcgtctaccaagatgctggagagattccccaacaat
ctgcccaaacatcgggaaaacgtgattcctgccgattcagagaagaagagctttgaggaa
gttatcaacctggttgaccagacttcagaaaacgcgcctaccaccatctcacaggatgtg
gaagagaaatacgagcatgcccctgccaagcccgaggcccccgtggactccatgctcaag
gacatcgccaccatcatcctgagcaccttcctgctcatcggctgggtggccttcatcatc
acctaccccttgagcatgcatcagcagcagcagctccagcaccagcagttccagaaggaa
ctagagaaaatccagctcctgcagcagcagcagctgcccttccatccacctggagacgtg
gctcaagatgctgagctcttggactcgtctggcctgtactccgagagctcaggcaccagc
agccccagcacgtcccccagagcctccaaccactcactccactccagtggctctgcctcc
aaggctggcgccagccccttcctggagcaggatgatgaggatgaggaaaccagcatggtg
atagtcgggaaaatttcattctgtcccaaggatgtgctgggtcatggagctgagggcacg
attgtgtaccggggcatgtttgacaaccgcgacgtggccgtcaagaggatcctccccgag
tgtttcagtttcgcagaccgggaagtccagctgcttcgagaatcggatgagcaccccaac
gtgatccgttacttctgcacggagagggaccggcagttccagtacattgccatcgagctg
tgtgcggccaccctgcaggagtacgtggagcagaaggactttgcccacctcggcctggag
cccatcaccttgctgcaacagaccacctcaggcctggcccatctgcactccctcaacatt
gttcacagagacctgaagccccacaacattctcctctccatgcccaacgcacatggcagg
atcaaggccatgatctcggacttcggcctctgcaagaagctggcagtcggcaggcacagt
ttcagccgccgctcaggagtgccgggcacagaaggctggattgctccagagatgctgagc
gaagactgcaaggacaacccgacctacacagtagacatcttctctgcgggctgtgtcttt
tactacgtgatatcggagggcagccacccttttggcaagtccctgcagcggcaggccaac
atcctcctgggtgcctacagcctcgactgcttgcaccccgagaagcacgaggatgtcatt
gcccgggaattaatagagaagatgatcgcaatggatcctcagaaacgcccttcggcgaag
cacgtgctgaaacacccgttcttctggagcctggaaaagcagctccagttctttcaggat
gtgagtgaccgaatagagaaggagtccctggacggcccgatagtgaagcagctggagcga
ggcgggagagctgtggtgaagatggactggagggagaacatcaccgtccccctgcagaca
gatctgcggaaattcagaacctataaaggtggctccgtccgagacctcctccgagccatg
agaaacaagaagcaccactaccgggagctccccgcggaggtgcgggagacgctgggctcc
ctccccgacgacttcgtgcgctacttcacgtcccgcttcccccacctcctgtcccacacc
taccgggccatggagccgtgcagccacgagcggctcttccagccctactacttccacgag
cccccagagccccggcctccagtgactccagacaccctttga
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integrated database retrieval system
