Ursus arctos (brown bear): 113266410
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Entry
113266410 CDS
T05909
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
3.6.4.10
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah03060
Protein export
uah04141
Protein processing in endoplasmic reticulum
uah04612
Antigen processing and presentation
uah04918
Thyroid hormone synthesis
uah05012
Parkinson disease
uah05014
Amyotrophic lateral sclerosis
uah05020
Prion disease
uah05022
Pathways of neurodegeneration - multiple diseases
uah05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
113266410 (HSPA5)
04141 Protein processing in endoplasmic reticulum
113266410 (HSPA5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
113266410 (HSPA5)
09152 Endocrine system
04918 Thyroid hormone synthesis
113266410 (HSPA5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
113266410 (HSPA5)
05014 Amyotrophic lateral sclerosis
113266410 (HSPA5)
05020 Prion disease
113266410 (HSPA5)
05022 Pathways of neurodegeneration - multiple diseases
113266410 (HSPA5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
113266410 (HSPA5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
uah03110
]
113266410 (HSPA5)
04131 Membrane trafficking [BR:
uah04131
]
113266410 (HSPA5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
uah04147
]
113266410 (HSPA5)
Enzymes [BR:
uah01000
]
3. Hydrolases
3.6 Acting on acid anhydrides
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.4.10 non-chaperonin molecular chaperone ATPase
113266410 (HSPA5)
Chaperones and folding catalysts [BR:
uah03110
]
Heat shock proteins
HSP70 / DNAK
113266410 (HSPA5)
Membrane trafficking [BR:
uah04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
113266410 (HSPA5)
Autophagy
ER-phagy
ER stress-related proteins
113266410 (HSPA5)
Exosome [BR:
uah04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
113266410 (HSPA5)
Exosomal proteins of other body fluids (saliva and urine)
113266410 (HSPA5)
Exosomal proteins of colorectal cancer cells
113266410 (HSPA5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
FtsA
DDR
FGGY_C
ParM_N
Motif
Other DBs
NCBI-GeneID:
113266410
NCBI-ProteinID:
XP_026369744
LinkDB
All DBs
Position
Unknown
AA seq
654 aa
AA seq
DB search
MKLSLVAAVLLLLGAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR
ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV
EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG
VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS
SQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV
LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC
PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG
TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER
MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE
KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGDEEPADKDEL
NT seq
1965 nt
NT seq
+upstream
nt +downstream
nt
atgaagctgtccctggtggctgcggtgctgctgctcctcggcgcggcgcgggccgaggag
gaggacaagaaggaggacgtgggcacggtggtcggcatcgacttggggaccacctactcc
tgcgtcggggtgttcaagaacggccgcgtggagatcatcgccaacgatcagggcaaccgc
atcacgccgtcttatgtggccttcactcctgaaggggagcgtttgatcggcgatgccgcc
aagaaccagctcacctccaaccctgagaacacggtcttcgacgccaagcggctcatcggc
cgcacatggaacgacccgtctgtgcagcaggacatcaagttcctgcctttcaaggttgtt
gagaagaaaactaaaccatacattcaagttgatattggaggtgggcaaacaaagacattt
gcccctgaagaaatttctgccatggttctcactaaaatgaaggaaactgcagaggcttat
ttaggaaagaaggttacccatgcagttgttactgtaccagcctatttcaatgatgcccaa
cgccaggcaaccaaagatgcaggaactattgctggattgaatgttatgaggatcattaat
gagcctacagcagccgctattgcttatggcttggataagcgggaaggggagaagaatatc
ctggtgtttgacttgggtggtggaacctttgatgtgtctcttctcaccattgacaatggt
gtcttcgaagtcgtggctactaatggagatactcatctggggggagaagactttgaccaa
cgtgtcatggaacacttcatcaaactctacaaaaagaagactggcaaagatgttaggaaa
gacaacagagctgtgcagaaactccggcgggaggtagaaaaggccaaacgggccctgtct
tctcaacatcaggcaagaattgaaattgagtctttctatgaaggggaagacttctctgag
actctgactcgggccaaatttgaagaactaaatatggatctgttccgttctaccatgaag
cctgttcagaaggtgctggaggattctgacttaaagaagtctgatattgatgaaattgtt
cttgttggtggctctactcgaatcccaaagattcaacaactggttaaagagttcttcaat
ggcaaggagccatcccgtggcatcaacccagatgaggctgtagcatacggtgctgctgtc
caggctggtgtactctctggtgatcaggatacaggtgatctggtactgcttgatgtatgt
ccccttacacttggtattgaaactgtgggaggtgtcatgaccaaactgattccaaggaac
accgtggtgcccacaaagaagtctcagatcttttctacagcttctgataaccaaccaact
gttacaatcaaggtctatgaaggtgaacgacccctgacaaaagacaatcaccttctggga
acttttgatctgactggaattcctcctgctccccgtggggtcccacagattgaagtcacc
tttgagatagatgtgaatggcattcttcgagtgacagctgaagacaaaggtacaggcaac
aaaaataagattacaattacgaatgaccaaaatcgcctgacacctgaagagattgaaagg
atggttaatgatgctgagaagtttgccgaggaagacaaaaagctcaaggagcgcattgat
actagaaatgaattggaaagctatgcctattctctaaagaatcagattggagataaagaa
aagctgggaggtaaactctcctctgaggataaggagaccatggaaaaagctgtagaggaa
aagattgaatggctagaaagtcatcaagatgctgacattgaagatttcaaagctaaaaag
aaggaactagaagaaattgttcagccaattatcagcaaactctatggaagtgcaggccct
cccccaactggtgatgaggaaccagcagacaaagatgagttgtag
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