Ursus arctos (brown bear): 113266547 Help Entry 113266547         CDS       T05909                                  Symbol TSC1 Name (RefSeq) hamartin isoform X1   KO K07206   tuberous sclerosis 1 Organism uah  Ursus arctos (brown bear) Pathway uah04072   Phospholipase D signaling pathway uah04140   Autophagy - animal uah04150   mTOR signaling pathway uah04151   PI3K-Akt signaling pathway uah04152   AMPK signaling pathway uah04211   Longevity regulating pathway uah04218   Cellular senescence uah04714   Thermogenesis uah04910   Insulin signaling pathway uah05163   Human cytomegalovirus infection uah05165   Human papillomavirus infection uah05168   Herpes simplex virus 1 infection uah05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:uah00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     113266547 (TSC1)    04151 PI3K-Akt signaling pathway     113266547 (TSC1)    04152 AMPK signaling pathway     113266547 (TSC1)    04150 mTOR signaling pathway     113266547 (TSC1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     113266547 (TSC1)   09143 Cell growth and death    04218 Cellular senescence     113266547 (TSC1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     113266547 (TSC1)   09149 Aging    04211 Longevity regulating pathway     113266547 (TSC1)   09159 Environmental adaptation    04714 Thermogenesis     113266547 (TSC1)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     113266547 (TSC1)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     113266547 (TSC1)    05163 Human cytomegalovirus infection     113266547 (TSC1)    05165 Human papillomavirus infection     113266547 (TSC1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hamartin Motif Other DBs NCBI-GeneID:  113266547 NCBI-ProteinID:  XP_026370032 LinkDB All DBs Position Unknown AA seq 1190 aa AA seqDB search MAQQANLGELLSMLDSPVLSVRDEVTAVFKENLSSDRGPMLVNTLVDYYLETKSQPVLHI LTTLQEPHDKHLLDKMNDCMGRAASRLPALSLLGHVIRLQPPWKHKLSQAPLLPSLLKCL KVDTDVIVLTTGVLVLITMLPMIPQSGKQHLHDFFDIFGRLSSWCLKKPGHVTEIYLVHL HASVYALFHRLYGMYPCNFVSFLRSHYSMKENLDTFEEVVRPMMEHVRIHPELVTGSKDH ELDPRRWKRLETHDVVIECAKISLDPAEASYEDGDSVSPQVSARFPHRAADVAASPYVDM QNSCGSATSTPYSSSRLTLFSTPGQPPQTLSPPSTRLLTEPPQATLWSPSMVCGMTTPPT SPGNVPPDLSHPYSKVFGTTGGKGTPLGTPATSPPPAPLCHSDDYVHISLRQATATPPKK NDVGEKGRHQTVRCMPPSSLTCVFSLKEEKTDSVRPCLHRQHHLPNDRGLEELPGSKGSV PLSDLPGFLGDLASEEDSIEKAKEEAAISKELSEITTAGTEPLVPRGGFDSPFYRDSLPG CPRKNHSAASGAQGASVNPEPLNSSLDKLGPDTPKQAFTPIDPPCGGANQSPAGSRERQT ALETDILTPSPCKIPPQRGVGFGSGQPPPYDHLFEVALPKTAHHFVSKKTKELLKKAKGN AEEDCPPSTSPAEVLDRLIQQGADAHSKELNKLSLPSKSVDWTHFGGSPPSDEIRTLRNQ LLLLHNQLLYERFKRQQHALRNRRLLRRVIRAAALEEHNAAMKDQLKLQEKDIQIWKVSM QKEQARYSQLQEQRDTMVTQLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRLEL KKANSKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQSKHSDTT KEVEMMKAACRKELEKNRSHVLQQNQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVK VQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLA SCKDGCSDSVTGHNEEASGHNGETKPPRPGGGVRGGGASRGGGGGSELSTPEKPPTQRAG LFSSRWETTVGESATSIPTTVGSFPSSKSFLGMKARELFRNKSESQCDEDSVTISSLSET LKTELGKDPGAEAKTPLHLDGPQPSPPSPDSVGQLHIMDYDETHQEHSEG NT seq 3573 nt NT seq  +upstreamnt  +downstreamnt atggcccagcaagcaaacctcggggagctcctgtccatgctggactcccctgtgctgagt gtgcgcgacgaggtgacagctgtctttaaagagaacctcagctctgaccgtggtccgatg ctcgtaaacaccctggtggattattacctggaaaccaagtctcagccggtattgcacatc ctgactaccttgcaagagccgcacgacaagcacctcttggacaaaatgaatgactgtatg ggcagagccgcctctcggctgcccgcgctgtcgctgctggggcacgtcatcaggctgcag ccgccttggaagcacaaactctctcaagcacctcttttgccttctttactcaaatgtctc aaggtggacaccgatgtcatcgtcctcacgacaggtgtcttagtgttgataaccatgcta ccaatgattccacagtcggggaagcagcaccttcatgatttctttgatatttttggccgt ctttcatcgtggtgcctgaagaaaccaggccacgtgacagaaatctatcttgtccatctc catgccagtgtttatgctctctttcatcgcctctacggaatgtacccttgcaactttgtc tcctttctacgctctcactacagtatgaaggagaacttggacactttcgaagaagtggtc aggccaatgatggagcacgtgcggattcacccggaattagtgactggatccaaagaccac gaactggacccgcgaaggtggaagcgattagaaacacatgatgttgtcatagagtgtgcc aaaatctctctggaccccgccgaagcctcgtacgaagatggcgactccgtgtccccgcag gtgtcagcgcgctttcctcatcgtgcggctgatgtggccgccagcccttacgtcgacatg cagaatagctgtgggagtgctacctcgaccccttattccagctctcggctgacattgttc agtacacccgggcagccacctcagactctgagtcccccatcgacacggctgttgactgag ccgccacaagctactctttggagcccgtctatggtttgtggtatgaccactccgccaact tctcctggaaatgtcccacctgatctgtcacacccttacagtaaagtctttggtacaact ggtgggaaaggaactcctctgggaaccccagcaacgtctcctcctcccgccccgctctgc cactcagacgactacgtgcacatttccctccggcaggccacagccacaccccccaagaag aatgatgtgggggagaagggccggcaccagactgtccggtgcatgccgccttcttccttg acgtgtgtcttcagcttaaaggaagagaaaacagattcagtaaggccctgtctacacaga cagcaccatctcccgaacgacagaggattagaagagttacctggcagcaaaggttctgtc cctctgagtgaccttccagggtttttaggggacctggcctccgaagaagatagcattgag aaagctaaagaagaagcggcgatatctaaagaactctccgagatcacgacagccggcacc gagcccctggttcctcgaggaggctttgactcccccttctaccgggacagtctcccgggc tgccctcgcaagaaccattcggccgcctctggtgctcagggcgccagtgtgaaccctgag cctttaaactcctccctggacaagcttgggcctgacacaccgaagcaagcctttactccc atagacccgccctgtggaggcgccaaccagagccctgccgggagcagggagcgccagact gcgctggagaccgacatcctcactcccagcccttgtaaaattccgcctcagaggggagtg gggtttggaagtgggcagcctcccccttacgatcatctttttgaggtggcattgccaaag accgcccatcattttgtcagcaagaagaccaaggaactgttaaagaaagcaaaaggaaac gcagaggaagactgtcctccctcgacctcccccgcggaagtcctggacagactcatccag cagggagcagacgcgcacagcaaggagctgaacaagttgtccttacccagcaagtctgtc gactggacccactttggaggctctcctccctcagatgagatccgcaccctccgtaaccag ttgcttttactgcacaaccagttgctctatgagcgttttaagaggcagcagcacgcgctc cggaacaggcggcttctccgcagggtgatcagggcggcggccctggaggagcacaacgcg gccatgaaagaccagttgaagttacaagagaaggacatccagatctggaaggttagcatg cagaaggagcaggcccggtacagccagttgcaggagcagcgagacaccatggtcacccag ctccacagccagatccgccagctgcagcacgaccgggaggagttctacaaccagagccag gagctgcagacaaagctagaggactgcaggaacatgatcgcagagctgcgtctggaattg aagaaggccaacagcaaggtgtgtcacaccgagctgctgctcagtcaggtgtcccagaag ctctcaaacagtgagtcggtccagcagcagatggagttcttgaaccggcagctcttggtc cttggggaggtcaacgagttgtatctggaacaactgcagagcaagcactcagacaccaca aaggaggtagagatgatgaaagctgcgtgtcggaaagaactagaaaaaaacagaagccac gttctgcagcagaatcagaggctcgatacctcccagaaacggattttggaactggaatct cacctggccaagaaagaccaccttcttttggagcagaagaaatatttagaggatgtcaaa gtccaggcaagaggacagctgcaggcggcagagagcaggtatgaggctcagaaaaggatc acccaagtgtttgaattggagatcttagatttatacggcaggttggagaaggatggcctc ctgaagaaacttgaagaagaaaaagcagaagcggccgaagcggcagaagaaaggcttgcc tcttgcaaggacggctgctcggattctgtaacagggcacaacgaagaggcatctggccac aatggcgagaccaagcccccccgacccggcggtggcgtgcggggtggcggtgcgagtaga gggggtggcggcggcagcgagctttcgaccccggagaaaccccccacccagagggcaggc ctgttcagcagtcggtgggaaactaccgtgggagagtccgccaccagcatccccacgact gtcggctcctttcccagttcaaaaagcttcctaggcatgaaggcgcgagagttatttcgt aataagagcgagagccagtgtgacgaggacagtgtgaccatcagtagcctttctgagacg ctaaagacagaactgggcaaagacccgggtgcggaagccaagacccccctgcacctcgac ggcccgcagccctcccccccgagcccggacagtgttggacagctgcacatcatggactac gacgagactcatcaggagcacagcgaagggtga

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