Ursus arctos (brown bear): 113266839
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Entry
113266839 CDS
T05909
Symbol
POLE
Name
(RefSeq) DNA polymerase epsilon catalytic subunit A
KO
K02324
DNA polymerase epsilon subunit 1 [EC:
2.7.7.7
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah03030
DNA replication
uah03410
Base excision repair
uah03420
Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09120 Genetic Information Processing
09124 Replication and repair
03030 DNA replication
113266839 (POLE)
03410 Base excision repair
113266839 (POLE)
03420 Nucleotide excision repair
113266839 (POLE)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
uah03032
]
113266839 (POLE)
03400 DNA repair and recombination proteins [BR:
uah03400
]
113266839 (POLE)
Enzymes [BR:
uah01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.7 DNA-directed DNA polymerase
113266839 (POLE)
DNA replication proteins [BR:
uah03032
]
Eukaryotic type
DNA Replication Elongation Factors
DNA polymerase epsilon complex
113266839 (POLE)
DNA repair and recombination proteins [BR:
uah03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
Long Patch-BER factors
DNA polymerase epsilon complex
113266839 (POLE)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DUF1744
POL2_thumb
DNA_pol_B_exo1
zf_DPOE_2
zf-DPOE
DNA_pol_B
DNA_pol_B_exo2
RNase_H_2
APP_N
CENP-B_dimeris
Motif
Other DBs
NCBI-GeneID:
113266839
NCBI-ProteinID:
XP_026370420
LinkDB
All DBs
Position
Unknown
AA seq
2283 aa
AA seq
DB search
MVLRNTGRRRAEPGPDGEASRDDGPSSSVSALKRLERSQWTDKMDSRFGFERLKEPGEKT
GWLVNMHPTEILDEDKRLVSAVDYYFIQDDGSRFKVALPYKPYFYIATRKGCEREVSSFL
SKKFQGKIAKVETVPKEDLDLPNHLVGLKRNYIKLSFNTVEDLVRVRKDVSPAVKKNREQ
GHASDAYTAMLSSVLQGGSVVIDEEEASKKVTDQLDNVVDMREYDVPYHIRLSIDLKIHV
AHWYNVRYRGSAFPVEISRRDDLVERPDPVVLAFDIETTKLPLKFPDPETDQIMMISYMI
DGQGYLITNREIVSDDVEDFEFTPKPEYEGPFCVFNEPDEGHLIQRWFEHVQETKPTIMV
TYNGDFFDWPFVEARAAIHGLSMYQEIGFQKDSQGEYKASQCIHMDCLRWVKRDSYLPVG
SHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFA
LCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHVLDSETYV
GGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTMRHAIEEEEKVPMEQVTNFQEVC
DQIKTKLTSLKDVPNRIECPLIYHLDVGAMYPNIILTNRLQPSAVVDEATCAACDFNKPG
ADCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPPLTAEGPPRAFHELSREEQAKYEK
RRLSDYCRKAYKKIHVTRVEERLTTVCQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLS
AAMELGDAAEVKRCKNMEVLYDSLQLAHKCILNSFYGYVMRRGARWYSMEMAGIVCFTGA
NIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVIKTASVKKPKVTISYPGAMLNIM
VKEGFTNDQYQELTEPSSLTYVTRAENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFN
EDGSLAELKGFEIKRRGELQLIKIFQSSVFEAFLKGSTLEDVYGSVAKVADYWLDVLYSK
AANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYII
SRKPEGSPVTERAIPLAIFQAEPMVRKHFLRKWLKSSSLQDFDIRTILDWDYYIERLGSA
IQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDVCKQKKISELFVLEGRRQVGTARA
PEGTQNLGAPDMEDFGLVKPPHSAVPVATKRKRILWESQEGSQDMELTVPWQEILGQPPA
LGTTQEEWLVWLRFHKKKWQLQARQRLARKKRRRVEVAEGGPLPGAVRDRPTTGLGSFLR
RTARSILDLPWQIVQISETGQAGLFRLWAVISSDLHCIRLSIPRVFYVNQRVAKAEEGPS
YRKVSRVLPRSNMVYNLYEYSVPEDMYQEHINEINTELSAPDIEGVYETQVPLLFRALVQ
LGCVCVVNKQLVRHLSGWEAETFALEHLEMRSLAQFSYLEPGSIRHLYLYHHAQGHKALF
GLFVPSQRRASVFVLDTVRSNQMPSLSALYSAEHSLLMERVGPELLPPPKHTFEVRAQTD
MKTICRAIQRSLLAYKEERRGPTLIAVQSNWELKRLASEVPVLEEFPLVPVHVADKISYG
VLDWQRLGARRMIRHYLNLDTCLSQAFEMSRYFHIPIGNLPEDISTFGSDLFFARHLQRH
SHLLWLSPTSRPDLGGKEADDNRLVMEFDDQASVEINYPGCYSTVCVELDIQNLAVNTIL
QSHHINDLEGADSVGISFDVIQQASLEDMITGNQAASTLASYDETALCSSTFRILKSMVV
GWVKEITQYHNIYADNQVMHFYRWLRSPSSLLHDPALHRTLHNMMKKLFLQLIAEFKRLG
SSVVYANFNRIVLCTRKRRIEDAVAYVEYVTSSIHSKEIFHSLTISFSRCWEFLLWMDPS
NYGGIKGDVPSRIHCGQQDSPKGGGEEEEEEEEEEEEEEEEEEGAQEPDVEDKLENSWNI
VQFLPQAASCQSYFLMIVSAYVVAVYHSMKEELRRSAPGGTPLRRRGPSQLSQDAPAAGA
LPGMITFSQDYVANELTQTFFTITQKIQKKVTGSRNSAELSGMFPLLPGSHLTLNNPALE
FVKYVCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCRSYVLPEVICRSCNF
CRDLDLCKESSFSQDGSVLPQWLCSNCQVAYDTSVIEMALVEALQKKLMAFTLQDLVCLK
CRGVKEANMPVYCSCAGGFALTIHTKVFMEQIGIFQNIAQHYGMSYLMETLEWLLQKGPQ
LGR
NT seq
6852 nt
NT seq
+upstream
nt +downstream
nt
atggtgctgaggaacaccgggcggcggcgcgcggagccgggcccggacggcgaggccagc
cgggatgatggcccctcttcctctgtctcggctcttaagcgcctggagcgcagtcagtgg
acggataagatggattcgcggtttggatttgagaggctcaaggagcccggcgagaagaca
ggctggctggtcaacatgcaccctactgagattttagatgaagacaaacgcttagtcagt
gcagtggattactactttattcaggatgatgggagcagatttaaggtggccttgccctac
aagccatatttctacattgcaaccagaaagggttgtgaacgagaagtttcatctttcctc
tccaagaagtttcagggtaaaattgctaaagtagagactgtccccaaagaggatctggac
ttgccaaatcacttggtgggtttgaagcgaaattacattaagctgtccttcaacaccgtg
gaggatcttgtcagagtgaggaaggacgtctcccctgctgtgaagaagaaccgggagcag
ggccatgccagtgatgcgtacacagctatgctctccagtgttctgcaagggggcagtgtg
gttatcgacgaagaggaagcctctaagaaggtcaccgaccagctggacaacgttgtggat
atgcgagagtatgacgtgccctaccacatccgcctctccatcgacctgaagatccacgtg
gctcattggtacaacgtcagataccgaggaagtgcctttcctgtggaaatctcccgacga
gatgaccttgttgaacgacccgaccctgtggttttggcatttgacatcgagacgaccaaa
ctgcccctcaagtttcccgaccctgagaccgaccagattatgatgatttcctatatgatt
gatggtcagggctacctcatcaccaacagggagatcgtttcagacgatgttgaagatttc
gagttcacccctaagccagagtacgaaggacctttttgtgtcttcaatgaaccagacgag
ggtcatctaatccagagatggtttgaacatgtccaggagaccaaacccaccatcatggtc
acctacaacggggacttttttgactggccgtttgtggaggccagagcggcgatccacgga
ctgagcatgtaccaggagatagggttccagaaggacagccagggggagtacaaggcatcc
cagtgcattcacatggactgtctcaggtgggtgaagagggacagttaccttcctgtgggc
agccacaacctcaaggcagctgcgaaagccaagctgggctacgaccccgtggagctggac
cccgaggacatgtgccggatggccactgagcagccccagactctggccacgtactcggtg
tcggacgcggtggccacgtactacctgtacatgaagtacgtccacccctttatcttcgcc
ctctgcaccatcatccccatggagcctgatgaggtgctgcggaagggctccgggactctg
tgtgaggccttgttgatggtgcaggccttccatgccaacatcatcttccccaacaagcag
gagcaggagtttaacaagctgacagacgacggtcacgtgctggactccgagacctatgtg
ggtggccacgtggaggccctcgagtcaggcgtgtttcgcagcgacatcccctgccggttc
aggatgaatcctgctgcctttgacttcctgctgcagcgggtggagaagaccatgcgtcac
gccatcgaggaagaggagaaggtgcccatggagcaggtcaccaacttccaagaggtgtgt
gatcagattaagaccaagctcacctccctgaaagatgttccgaacagaatagagtgtccc
cttatctaccacctggatgtgggggccatgtaccccaacatcatcctgacgaaccgtctg
cagccgtctgccgtggtggacgaggccacctgtgctgcctgtgacttcaacaagccggga
gcagactgccagaggaagatggcctggcagtggaggggcgagttcatgccagccagccgc
agcgagtaccatcggatccagcaccagctggagtcggagaagttccctcccttgactgca
gagggtccgccccgggcctttcacgagctgtcccgcgaggagcaggctaaatacgagaag
cggaggctgtcagattactgccggaaggcgtacaagaagatccacgtgaccagggtggag
gagcgcctcaccaccgtctgccagcgggagaactctttctacgtggacacggtgcgcgcc
ttccgagacaggcgctacgagttcaagggtctccacaaggtgtggaagaagaagctctcc
gcggccatggagctgggcgacgcggccgaggtgaagcgctgcaagaacatggaggtcctg
tacgactcgctgcagctggcgcacaagtgcatcctcaactccttctacggctacgtcatg
cgtagaggggcccgctggtactccatggagatggcaggcattgtctgcttcacgggggcc
aacatcatcacccaggcacgggagctgatcgaacagatcgggaggcccctggagctggac
acagatggaatatggtgcgtcctgcccaacagcttccctgaaaactttgtcatcaagacg
gccagtgtgaaaaagcccaaggtgaccatttcctaccccggggccatgttaaacatcatg
gtcaaggagggctttaccaacgatcagtaccaggagctgactgagccgtcctcactcacc
tatgtcacccgcgcagagaacagcatctttttcgaggttgacggaccgtaccttgccatg
atccttccagcctccaaggaagaaggcaagaaactgaagaagagatacgccgtcttcaat
gaggatggctccctggctgagctaaagggcttcgagatcaagcgccgaggggagctgcag
ctgatcaagatcttccagtcctccgtgttcgaggccttccttaagggcagcacgctggaa
gacgtgtacggctctgttgccaaggtggctgattactggctggacgtgctgtacagcaaa
gcagccaacatgccggattctgagctgtttgagctgatctctgagaaccgctccatgtct
cggaagctggaagattatggggagcagaagtccacgtctatcagcacagccaagcgcctg
gctgagttcctgggggatcagatggtgaaggacgcggggctgagctgccgctacatcatc
tcccggaagcccgaggggtctcccgtcacggagagggccatcccgctagccattttccag
gccgagcccatggtgaggaagcactttctccggaaatggcttaagagttcttcgctccaa
gactttgatattcggacgattctggattgggactactacatcgagcgtctggggagtgcc
atacagaagatcatcacaatcccggcggctctgcagcaggtgaagaacccagtgccacgc
gtcaagcaccccgactggctgcacaagaagcttctggagaagaacgacgtctgcaagcag
aagaagatcagtgagctctttgtccttgagggcaggagacaggtgggcacggcccgggct
ccagaaggcacgcagaaccttggtgctcctgacatggaggattttggccttgtgaagcca
ccgcactcggcggttcctgttgccacgaagaggaagcgcatcctctgggagagccaggag
gggtcgcaggacatggagctgacggtgccctggcaggaaatcttggggcagcctccggcc
ctcggaaccacccaggaagagtggctggtctggctccggttccataagaagaagtggcag
ctgcaggcccggcagcggctggctcgcaagaagaggcggcgtgtggaggtggcggagggc
ggacctctgcccggggccgtccgagacaggcccaccaccgggctggggagcttcctgcga
aggactgcccgcagcatcttggaccttccgtggcagatcgtgcagatcagtgagaccggc
caggcggggctgttcaggctgtgggccgtcatcagcagtgacttgcactgcatccggctg
agcatcccccgcgtgttctacgtcaaccagcgggtggccaaagccgaggaggggccttca
tatcgcaaggtcagccgcgtccttccgcgctccaacatggtctacaacctctatgagtac
tcggtgcccgaggacatgtaccaggaacacatcaacgagatcaacaccgagttgtcagcc
ccggacattgagggcgtgtacgagactcaggtcccgttactgttccgggccctggtgcag
ctgggctgtgtgtgtgtggtcaacaaacagctggtgaggcacctttcaggctgggaggcg
gagacctttgctctcgagcacctggagatgcgctctctggcccagttcagctacctggaa
ccaggcagcatccgccacctctacctgtatcatcacgcgcagggccacaaagcgctcttc
ggcttgttcgtgccctcccagcgcagagcgtctgtgtttgtgttggacaccgtgcgaagc
aaccagatgcccagcctcagcgctctgtactcagccgagcacagcctcctgatggagaga
gtgggtcctgagctcctgcctccccccaaacacactttcgaggttcgggcccaaacggac
atgaagaccatctgcagggccatccagcgctccctgctggcctacaaagaggagcgccgg
gggcccacactcatcgccgtgcagtccaactgggagctgaagaggctggctagcgaggtt
cccgtcctggaggagttcccgctggtgcctgtccatgtggccgataagatcagctatgga
gtcctggactggcagcgccttggggcccggcgcatgatccgccactacctcaacctcgac
acctgtctgtcacaggccttcgagatgagccggtacttccacatccccattggtaatctg
cctgaggacatctccacctttggctccgacctcttctttgcccgccaccttcagcgccac
agccacctgctctggctgtcccctacgtcacgccctgacctgggcggcaaggaggccgat
gacaatcgcctcgtcatggagtttgatgaccaggccagtgtggagatcaactatccaggc
tgctactctacggtgtgcgtggagctggacatccagaacctggctgtgaacaccatcctg
cagtcccaccatatcaatgacctggaaggggccgacagcgtgggcatcagcttcgatgtg
atccagcaggcctccctggaggacatgatcaccggcaatcaggccgccagcaccctggcc
agctacgacgagacagcgctctgctccagcaccttcaggatcctgaagagcatggtggtg
ggctgggtgaaagagatcacgcagtaccacaacatctacgccgacaaccaggtgatgcac
ttctaccgctggctgcggtccccgtcctcgctgctccacgaccctgctctgcaccgcacg
ctccacaacatgatgaagaagctctttctgcagctcatcgccgagttcaagcgcttgggg
tcatctgtcgtctatgccaacttcaaccgcatcgtcctctgcacgagaaagcggcggatt
gaggacgccgttgcctacgtggagtacgtcaccagcagcatccattctaaagagatcttc
cattccttgacaatttcattctctcggtgctgggaatttcttctgtggatggatccctcc
aactatggtggaatcaaaggagacgttccatctcgtattcactgtggacagcaagactcc
ccaaaagggggtggagaggaggaagaggaggaggaggaggaggaggaggaggaggaggag
gaggaggaaggcgcacaggagcccgatgtggaggacaagctggagaacagctggaacatc
gtgcaattcctgccacaggcggcctcgtgccagagctacttcctcatgatcgtgtcagcc
tacgtggtggccgtgtaccatagcatgaaggaggagctgcggcgcagcgccccagggggc
acgcccctgagacgccgggggcccagccagctgtcccaggacgccccggcggccggcgcc
cttcccggaatgatcaccttctcacaagactacgtggccaacgagctcacgcagaccttc
ttcaccatcactcagaagattcagaagaaggtcacgggctcgcggaactccgccgagctg
tccggcatgtttccgctgctccccggttcccacctgacgctcaacaaccctgcgctggag
ttcgtcaagtacgtgtgcaaggttctgtctctggacacgaacatcacaaaccaggtgaac
aagttgaaccgggacctgcttcgcctggtggacgtgggcgagttctcggaggaggcccag
ttccgagacccctgccgttcctacgtgctccctgaggtcatctgccgcagctgtaacttc
tgccgggacctggacctgtgcaaagagtcctccttctctcaggacgggtctgtgctgcct
cagtggctctgctccaactgtcaggttgcctatgacacctcagtcatcgagatggctctg
gtggaagccctgcagaagaagctgatggccttcactctgcaggacctggtctgcctgaag
tgccggggtgtgaaggaggccaacatgcctgtgtactgcagctgtgcggggggcttcgcc
ctcaccatccacaccaaggtcttcatggagcagattggaatcttccagaacatcgcccag
cactacggcatgtcctacctcatggagaccctggagtggctgctgcagaagggccctcag
ctgggccgttag
DBGET
integrated database retrieval system
