KEGG   Ursus arctos (brown bear): 113267584
Entry
113267584         CDS       T05909                                 
Symbol
PRKCB
Name
(RefSeq) protein kinase C beta type isoform X1
  KO
K19662  classical protein kinase C beta type [EC:2.7.11.13]
Organism
uah  Ursus arctos (brown bear)
Pathway
uah01521  EGFR tyrosine kinase inhibitor resistance
uah04010  MAPK signaling pathway
uah04012  ErbB signaling pathway
uah04014  Ras signaling pathway
uah04015  Rap1 signaling pathway
uah04020  Calcium signaling pathway
uah04062  Chemokine signaling pathway
uah04064  NF-kappa B signaling pathway
uah04066  HIF-1 signaling pathway
uah04070  Phosphatidylinositol signaling system
uah04071  Sphingolipid signaling pathway
uah04082  Neuroactive ligand signaling
uah04150  mTOR signaling pathway
uah04270  Vascular smooth muscle contraction
uah04310  Wnt signaling pathway
uah04370  VEGF signaling pathway
uah04510  Focal adhesion
uah04517  IgSF CAM signaling
uah04540  Gap junction
uah04613  Neutrophil extracellular trap formation
uah04650  Natural killer cell mediated cytotoxicity
uah04662  B cell receptor signaling pathway
uah04666  Fc gamma R-mediated phagosome formation
uah04670  Leukocyte transendothelial migration
uah04713  Circadian entrainment
uah04720  Long-term potentiation
uah04723  Retrograde endocannabinoid signaling
uah04724  Glutamatergic synapse
uah04725  Cholinergic synapse
uah04726  Serotonergic synapse
uah04727  GABAergic synapse
uah04728  Dopaminergic synapse
uah04730  Long-term depression
uah04750  Inflammatory mediator regulation of TRP channels
uah04911  Insulin secretion
uah04912  GnRH signaling pathway
uah04916  Melanogenesis
uah04918  Thyroid hormone synthesis
uah04919  Thyroid hormone signaling pathway
uah04921  Oxytocin signaling pathway
uah04925  Aldosterone synthesis and secretion
uah04928  Parathyroid hormone synthesis, secretion and action
uah04929  GnRH secretion
uah04931  Insulin resistance
uah04933  AGE-RAGE signaling pathway in diabetic complications
uah04935  Growth hormone synthesis, secretion and action
uah04960  Aldosterone-regulated sodium reabsorption
uah04961  Endocrine and other factor-regulated calcium reabsorption
uah04970  Salivary secretion
uah04971  Gastric acid secretion
uah04972  Pancreatic secretion
uah04973  Carbohydrate digestion and absorption
uah05017  Spinocerebellar ataxia
uah05022  Pathways of neurodegeneration - multiple diseases
uah05031  Amphetamine addiction
uah05032  Morphine addiction
uah05140  Leishmaniasis
uah05143  African trypanosomiasis
uah05146  Amoebiasis
uah05161  Hepatitis B
uah05163  Human cytomegalovirus infection
uah05164  Influenza A
uah05170  Human immunodeficiency virus 1 infection
uah05171  Coronavirus disease
uah05200  Pathways in cancer
uah05205  Proteoglycans in cancer
uah05206  MicroRNAs in cancer
uah05207  Chemical carcinogenesis - receptor activation
uah05214  Glioma
uah05223  Non-small cell lung cancer
uah05225  Hepatocellular carcinoma
uah05231  Choline metabolism in cancer
uah05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:uah00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    113267584 (PRKCB)
   04012 ErbB signaling pathway
    113267584 (PRKCB)
   04014 Ras signaling pathway
    113267584 (PRKCB)
   04015 Rap1 signaling pathway
    113267584 (PRKCB)
   04310 Wnt signaling pathway
    113267584 (PRKCB)
   04370 VEGF signaling pathway
    113267584 (PRKCB)
   04064 NF-kappa B signaling pathway
    113267584 (PRKCB)
   04066 HIF-1 signaling pathway
    113267584 (PRKCB)
   04020 Calcium signaling pathway
    113267584 (PRKCB)
   04070 Phosphatidylinositol signaling system
    113267584 (PRKCB)
   04071 Sphingolipid signaling pathway
    113267584 (PRKCB)
   04150 mTOR signaling pathway
    113267584 (PRKCB)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    113267584 (PRKCB)
   04517 IgSF CAM signaling
    113267584 (PRKCB)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    113267584 (PRKCB)
   04540 Gap junction
    113267584 (PRKCB)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    113267584 (PRKCB)
   04650 Natural killer cell mediated cytotoxicity
    113267584 (PRKCB)
   04662 B cell receptor signaling pathway
    113267584 (PRKCB)
   04666 Fc gamma R-mediated phagosome formation
    113267584 (PRKCB)
   04670 Leukocyte transendothelial migration
    113267584 (PRKCB)
   04062 Chemokine signaling pathway
    113267584 (PRKCB)
  09152 Endocrine system
   04911 Insulin secretion
    113267584 (PRKCB)
   04929 GnRH secretion
    113267584 (PRKCB)
   04912 GnRH signaling pathway
    113267584 (PRKCB)
   04921 Oxytocin signaling pathway
    113267584 (PRKCB)
   04935 Growth hormone synthesis, secretion and action
    113267584 (PRKCB)
   04918 Thyroid hormone synthesis
    113267584 (PRKCB)
   04919 Thyroid hormone signaling pathway
    113267584 (PRKCB)
   04928 Parathyroid hormone synthesis, secretion and action
    113267584 (PRKCB)
   04916 Melanogenesis
    113267584 (PRKCB)
   04925 Aldosterone synthesis and secretion
    113267584 (PRKCB)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    113267584 (PRKCB)
  09154 Digestive system
   04970 Salivary secretion
    113267584 (PRKCB)
   04971 Gastric acid secretion
    113267584 (PRKCB)
   04972 Pancreatic secretion
    113267584 (PRKCB)
   04973 Carbohydrate digestion and absorption
    113267584 (PRKCB)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    113267584 (PRKCB)
   04961 Endocrine and other factor-regulated calcium reabsorption
    113267584 (PRKCB)
  09156 Nervous system
   04724 Glutamatergic synapse
    113267584 (PRKCB)
   04727 GABAergic synapse
    113267584 (PRKCB)
   04725 Cholinergic synapse
    113267584 (PRKCB)
   04728 Dopaminergic synapse
    113267584 (PRKCB)
   04726 Serotonergic synapse
    113267584 (PRKCB)
   04720 Long-term potentiation
    113267584 (PRKCB)
   04730 Long-term depression
    113267584 (PRKCB)
   04723 Retrograde endocannabinoid signaling
    113267584 (PRKCB)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    113267584 (PRKCB)
  09159 Environmental adaptation
   04713 Circadian entrainment
    113267584 (PRKCB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    113267584 (PRKCB)
   05206 MicroRNAs in cancer
    113267584 (PRKCB)
   05205 Proteoglycans in cancer
    113267584 (PRKCB)
   05207 Chemical carcinogenesis - receptor activation
    113267584 (PRKCB)
   05231 Choline metabolism in cancer
    113267584 (PRKCB)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    113267584 (PRKCB)
   05214 Glioma
    113267584 (PRKCB)
   05223 Non-small cell lung cancer
    113267584 (PRKCB)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    113267584 (PRKCB)
   05161 Hepatitis B
    113267584 (PRKCB)
   05171 Coronavirus disease
    113267584 (PRKCB)
   05164 Influenza A
    113267584 (PRKCB)
   05163 Human cytomegalovirus infection
    113267584 (PRKCB)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    113267584 (PRKCB)
   05140 Leishmaniasis
    113267584 (PRKCB)
   05143 African trypanosomiasis
    113267584 (PRKCB)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    113267584 (PRKCB)
   05022 Pathways of neurodegeneration - multiple diseases
    113267584 (PRKCB)
  09165 Substance dependence
   05031 Amphetamine addiction
    113267584 (PRKCB)
   05032 Morphine addiction
    113267584 (PRKCB)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    113267584 (PRKCB)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    113267584 (PRKCB)
   04933 AGE-RAGE signaling pathway in diabetic complications
    113267584 (PRKCB)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    113267584 (PRKCB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:uah01001]
    113267584 (PRKCB)
Enzymes [BR:uah01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     113267584 (PRKCB)
Protein kinases [BR:uah01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   113267584 (PRKCB)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C Kinase-like ABC1 CEP76-C2
Other DBs
NCBI-GeneID: 113267584
NCBI-ProteinID: XP_026371400
LinkDB
Position
Unknown
AA seq 673 aa
MADPAAGPPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGS
LLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIEREVLIVVVRDA
KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRL
SVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFKLLSQEEGEYFNVPVPPEGSEGNEE
LRQKFERAKISQGTKAPEEKTTNTISKLDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSE
RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVM
EYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHI
KIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP
FEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFF
RYIDWEKLERKEIQPPYKPKACGRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFS
FVNSEFLKPEVKS
NT seq 2022 nt   +upstreamnt  +downstreamnt
atggctgacccggctgcggggccgccgccgagcgagggcgaggagagcaccgtgcgcttc
gcccgcaaaggcgccctccggcagaagaacgtgcacgaggtgaagaaccacaaattcacc
gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggggcttc
ggaaagcaaggattccagtgccaagtctgctgttttgttgtgcacaagcggtgccatgaa
tttgtcaccttctcctgcccaggcgccgacaaaggcccagcctccgatgacccccggagc
aaacacaagtttaagatccacacgtactccagccccacgttttgtgaccactgtgggtca
ctgctgtatggactcatccaccaggggatgaagtgtgacacctgcatgatgaacgtgcac
aagcgctgcgtgatgaacgtccccagcctgtgcggcacagaccacacggagcgccgcggc
cgcatctacatccaggcccacatcgagagggaagtcctcatcgtagtcgtaagagatgct
aaaaaccttgtacctatggaccccaatggcttgtcagacccttacgtgaaactgaaactg
attcctgaccccaagagcgagagcaagcagaagaccaaaaccatcaagtgctccctcaac
cctgagtggaatgagacattcagattccaactgaaagaatcggacaaagacagaagactg
tctgtagagatttgggattgggatctgaccagcaggaatgacttcatgggatctttgtcg
tttgggatttccgaactgcagaaagctggtgttgatggctggtttaagctgctgagccag
gaggaaggcgagtacttcaatgtgcctgtgccgccggaaggaagcgaaggcaatgaagag
ctgcggcagaaattcgagagggccaagatcagtcaggggaccaaggctccagaagaaaag
acgaccaacaccatatccaaacttgacaacaacgggaacagagaccgaatgaaactgacc
gattttaacttcctgatggtgctcgggaaaggaagctttggcaaggtcatgctctctgag
cgaaaaggcacggacgagctctatgctgtgaagatcctgaagaaggacgtcgtgatccag
gatgacgatgtggagtgcacgatggtggagaagcgggtgctggccctgcctggaaagccg
ccgttcctgacccaactgcattcctgcttccagaccatggaccgcctgtactttgtgatg
gagtatgtgaacgggggcgacctcatgtaccacatccaacaagtcggccggtttaaggag
cctcacgctgtattttacgctgccgaaattgccatcggtctgttcttcttacagagcaag
ggcatcatttaccgtgacctcaaacttgacaatgtgatgctggattcagagggccacatc
aagattgctgattttggcatgtgcaaagaaaacatctgggatggggtgaccaccaagaca
ttctgtggcactccagactacatcgcccctgagatcattgcctaccagccctatgggaag
tctgtggattggtgggcctttggagtcctgctgtatgaaatgttggctgggcaggcaccc
tttgaaggggaggatgaggatgaactcttccagtccatcatggaacacaatgtggcttac
cccaagtccatgtccaaggaagctgtggccatctgcaaagggctgatgaccaaacacccg
ggcaaacgtctgggttgcggacccgaaggtgaacgtgacatcaaggagcatgcgtttttc
cggtatattgattgggagaaacttgaacgcaaagagattcagcccccgtataagccaaaa
gcctgtgggcgaaatgctgaaaacttcgaccggtttttcacccgccatccaccagtccta
acacctcccgaccaggaagtcatcaggaatattgaccagtcagaattcgaaggattttcc
tttgttaactctgaatttttaaaacctgaagtcaagagctaa

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