Ursus arctos (brown bear): 113268357 Help Entry 113268357         CDS       T05909                                  Symbol HDAC1 Name (RefSeq) histone deacetylase 1 isoform X2   KO K06067   histone deacetylase 1/2 [EC:3.5.1.98] Organism uah  Ursus arctos (brown bear) Pathway uah03082   ATP-dependent chromatin remodeling uah03083   Polycomb repressive complex uah04110   Cell cycle uah04213   Longevity regulating pathway - multiple species uah04330   Notch signaling pathway uah04350   TGF-beta signaling pathway uah04613   Neutrophil extracellular trap formation uah04919   Thyroid hormone signaling pathway uah05016   Huntington disease uah05031   Amphetamine addiction uah05034   Alcoholism uah05165   Human papillomavirus infection uah05169   Epstein-Barr virus infection uah05200   Pathways in cancer uah05202   Transcriptional misregulation in cancer uah05203   Viral carcinogenesis uah05206   MicroRNAs in cancer uah05220   Chronic myeloid leukemia Brite KEGG Orthology (KO) [BR:uah00001]  09120 Genetic Information Processing   09126 Chromosome    03082 ATP-dependent chromatin remodeling     113268357 (HDAC1)    03083 Polycomb repressive complex     113268357 (HDAC1)  09130 Environmental Information Processing   09132 Signal transduction    04330 Notch signaling pathway     113268357 (HDAC1)    04350 TGF-beta signaling pathway     113268357 (HDAC1)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     113268357 (HDAC1)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     113268357 (HDAC1)   09152 Endocrine system    04919 Thyroid hormone signaling pathway     113268357 (HDAC1)   09149 Aging    04213 Longevity regulating pathway - multiple species     113268357 (HDAC1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     113268357 (HDAC1)    05202 Transcriptional misregulation in cancer     113268357 (HDAC1)    05206 MicroRNAs in cancer     113268357 (HDAC1)    05203 Viral carcinogenesis     113268357 (HDAC1)   09162 Cancer: specific types    05220 Chronic myeloid leukemia     113268357 (HDAC1)   09172 Infectious disease: viral    05169 Epstein-Barr virus infection     113268357 (HDAC1)    05165 Human papillomavirus infection     113268357 (HDAC1)   09164 Neurodegenerative disease    05016 Huntington disease     113268357 (HDAC1)   09165 Substance dependence    05031 Amphetamine addiction     113268357 (HDAC1)    05034 Alcoholism     113268357 (HDAC1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:uah03036]     113268357 (HDAC1) Enzymes [BR:uah01000]  3. Hydrolases   3.5  Acting on carbon-nitrogen bonds, other than peptide bonds    3.5.1  In linear amides     3.5.1.98  histone deacetylase      113268357 (HDAC1) Chromosome and associated proteins [BR:uah03036]  Eukaryotic type   Histone modification proteins    HDACs (histone deacetylases)     Class I HDACs      113268357 (HDAC1)    HDAC complexes     Sin3A-HDAC complex      113268357 (HDAC1)     BRAF-HDAC complex      113268357 (HDAC1)     REST complex      113268357 (HDAC1)     SHIP complex      113268357 (HDAC1)     MiDAC complex      113268357 (HDAC1)    Polycomb repressive complex (PRC) and associated proteins     Noncanonical PRC1 (PRC1.6)      113268357 (HDAC1)   Heterochromatin formation proteins    Other heterochromatin formation proteins     113268357 (HDAC1)   Chromatin remodeling factors    NuRD complex     113268357 (HDAC1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hist_deacetyl Motif Other DBs NCBI-GeneID:  113268357 NCBI-ProteinID:  XP_026372576 LinkDB All DBs Position Unknown AA seq 482 aa AA seqDB search MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKAN AEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAS AVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHG DGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAI FKPVISKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGG GGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLE KIKQRLFENLRMLPHAPGVQMQVIPEDAIPEESGDEDEEDPDKRISICSSDKRIACEEEF SDSDEEGEGGRKNASNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKQEAKGVKEEVK LA NT seq 1449 nt NT seq  +upstreamnt  +downstreamnt atggcgcagactcagggcaccaggaggaaagtctgttactactacgacggggatgttgga aattactactatggacaaggccacccaatgaagcctcaccgaatccgcatgactcacaat ttgctacttaactatggtctctaccgaaaaatggaaatctatcgcccgcacaaagccaat gctgaggagatgaccaagtaccacagcgacgactacattaaattcctgcgctccatccgc ccagataacatgtccgagtacagcaagcagatgcagagattcaacgtcggtgaggactgt ccagtatttgatggcctgtttgaattctgtcagttatctactgggggctctgtggcgagt gctgtgaaactgaataagcagcagacggacatcgccgtgaattgggccgggggcctgcac cacgcaaagaagtctgaggcatctggcttctgttacgtcaatgatatcgtcttggccatc ctggagctgctaaagtatcaccagagggtgctgtatattgacattgatattcaccacggc gatggcgtggaagaggccttctataccacagaccgggtcatgactgtgtcctttcataaa tacggagagtacttcccaggaactggggacctacgggacattggggctggcaaaggcaag tattacgctgttaactacccgctccgagatgggatcgatgacgagtcctatgaggccatt ttcaagccggtcatatctaaagtgatggagatgttccagcccagtgcggttgtcttacag tgtggctctgactccctgtctggggatcggttaggttgcttcaatctgaccatcaaaggg catgccaagtgtgtggagtttgtgaagagcttcaacctgcctatgctgatgctgggcgga ggcggctacaccatccgtaacgtggcccgctgctggacgtacgaaacggctgtggccctg gacacggagatcccgaatgagcttccgtacaacgactacttcgaatactttgggccagat ttcaaacttcacatcagtccttccaatatgaccaaccagaataccaatgaatacctggag aagatcaaacagcgactgtttgagaacctgagaatgctgccccacgcacctggggtccaa atgcaggtgattcctgaggatgccattccagaggagagtggcgacgaggacgaagaagac cctgacaagcgtatctcgatctgttcttctgacaagcgaattgcctgtgaggaagagttc tcagactccgatgaggagggagaaggtggtcgcaagaacgcttccaacttcaaaaaagcc aagagagtcaaaactgaggatgaaaaagagaaagacccagaagagaagaaagaagtcaca gaagaggagaaaaccaaggaggagaagcaagaagccaaaggggtcaaggaggaggtcaag ttggcttga

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