Ursus arctos (brown bear): 113268927
Help
Entry
113268927 CDS
T05909
Symbol
ACACA
Name
(RefSeq) acetyl-CoA carboxylase 1 isoform X4
KO
K11262
acetyl-CoA carboxylase / biotin carboxylase 1 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah00061
Fatty acid biosynthesis
uah00620
Pyruvate metabolism
uah00640
Propanoate metabolism
uah01100
Metabolic pathways
uah01212
Fatty acid metabolism
uah04152
AMPK signaling pathway
uah04910
Insulin signaling pathway
uah04922
Glucagon signaling pathway
uah04936
Alcoholic liver disease
Module
uah_M00082
Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
113268927 (ACACA)
00640 Propanoate metabolism
113268927 (ACACA)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
113268927 (ACACA)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
113268927 (ACACA)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
113268927 (ACACA)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
113268927 (ACACA)
04922 Glucagon signaling pathway
113268927 (ACACA)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
113268927 (ACACA)
Enzymes [BR:
uah01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
113268927 (ACACA)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
113268927 (ACACA)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
113268927 (ACACA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
113268927
NCBI-ProteinID:
XP_026373320
LinkDB
All DBs
Position
Unknown
AA seq
2346 aa
AA seq
DB search
MDEPSPLAKPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVGSDTLS
DLGISSLQDGLALHMRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEK
VLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPG
GPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWAL
GDKIASSIVAQTAGIPTLPWSGSGLRVDWHENDFSKRILNVPQELYEKGYVKDVDDGLKA
AEEVGYPVMIKASEGGGGKGIRKVNSADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEV
QILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSA
GTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMY
GVSPWGDAPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGY
FSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLET
ESFQLNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQV
LPAHTLLNTVDVELIYGGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDG
SSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVLRSPSAGKLIQYIVEDGGHVFAGQCYA
EIEVMKMVMTLTAAESGCIHYVKRPGTALDPGCVIAKMQLDNPSKVQQAELHTGSLPRIQ
STALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQ
DIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANTLDSHAATLNRKSEREV
FFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSD
MNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALR
ARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYH
SNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRM
SFSSNLNHYGMTHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSP
PQSPTFPEAGHTSLYDEDKVPRDEPIHILNVAIKTDCDIEDDGLAAMFREFTQQNKATLV
EHGIRRLTFLVAQKDFRKQVNCEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQ
LELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFE
YLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYG
SRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQA
YGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQA
FLPSPPLPSDMLTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTLKSPEYPEGRDIIVI
GNDITYRIGSFGPQEDLLFLRASELARAEGIPRIFVAANSGARIGLAEEIRHMFHVAWVD
PEDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGVENLRGS
GMIAGESSLAYDEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGR
EVYTSNNQLGGIQIMHNNGVTHSIVCDDFEGVFTVLHWLSYMPKSVCSSVPLLNSKDPID
RIIEFVPTKAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGG
IPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPL
MVFANWRGFSGGMKDMYDQVLKFGAYIVDSLRECSQPVLVYIPPQAELRGGSWVVIDPTI
NPRHMEMYADRESRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIRLAERLGTPELSPAE
RKELENKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLR
RLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTE
EDGVRSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILST
MDSPST
NT seq
7041 nt
NT seq
+upstream
nt +downstream
nt
atggatgaaccatcccctttggccaaacctctggagctgaaccagcactcccgattcata
attggttctgtgtctgaagataactcagaggatgaaattagcaacctggtgaagctggat
ctactggaggagaaggagggctctctgtcaccggcgtctgttggctcagatacactctct
gatttggggatctccagcctacaggatggcttggccttacacatgaggtccagcatgtct
ggcttgcatctagtaaagcaaggtcgagaccgaaagaaaatagactcccagcgagatttc
actgtagcttctccagcagaatttgttactcgttttggggggaataaagtgattgagaag
gttcttattgccaacaatggcattgcagcagtgaaatgcatgcggtctatccgtcgatgg
tcttatgagatgtttcgaaatgaacgtgcaatccgatttgttgttatggtaacacccgaa
gacctgaaagccaatgcagaatacattaagatggcagatcactatgtgccagtgccagga
ggaccaaacaacaacaactatgcaaacgtggaattaattcttgatattgctaaaaggatt
ccagtacaagcagtgtgggctggctggggtcatgcttctgagaatcccaagctcccagaa
cttcttttgaaaaatggcatcgccttcatgggtcctccaagccaggccatgtgggctttg
ggggataagattgcatcttccatagtggctcagactgcaggtatcccaactcttccctgg
agtggcagtggtcttcgtgtggactggcatgaaaatgatttttcaaaacgtatcttaaat
gttccccaggaattatatgaaaaaggttatgtgaaggatgtggacgatgggctgaaggca
gcagaggaagttggatatccagtaatgatcaaggcctcagaaggaggtggagggaaagga
atcagaaaagtcaacagtgcagatgacttccctaatctcttcagacaggtgcaagctgaa
gtccctggatctcctatatttgtgatgagactagccaaacaatctcgtcatctggaggta
cagatcttagcagatcagtatggcaatgctatctctctctttggccgtgactgctctgta
cagcgcaggcatcagaagattattgaggaagcacctgctgcgatcgctactccagctgtg
tttgaacatatggaacagtgtgcggtgaaacttgccaaaatggttggttatgtgagtgct
gggactgtggaatacctctacagccaggatgggagcttctactttctggaactgaaccct
cggctgcaggtggagcacccctgtacagagatggtggctgatgtcaacctccccgcagca
caactccagattgccatggggatccctctgtacagaatcaaggatattcgtatgatgtat
ggggtatctccctggggcgatgctcccattgattttgaaaattctgctcatgttccttgc
ccaaggggccatgttattgctgctcggatcaccagtgaaaatccagatgagggttttaag
cccagctcaggaacagttcaggaactgaatttccgaagcaataagaatgtttggggttat
ttcagtgttgctgctgcagggggccttcatgagtttgctgattctcagtttggtcactgc
ttctcctggggagaaaacagagaggaagcaatttcaaacatggtggtggctttgaaggag
ctatctattcggggtgactttcgaactacagttgaatacctcatcaaattgttggagact
gaaagctttcagttgaatagaattgacactggctggctggacaggctgatagcagagaaa
gtacaggcagagcgacctgacaccatgttgggagttgtatgtggggctctccacgtggca
gatgtgagcctacggaatagcatctctaacttccttcactccttagaaaggggtcaagtc
cttcctgcgcatacacttctgaatacagtagatgttgagcttatctatgggggagtcaaa
tatgtacttaaggtgacccggcagtctcccaactcctatgtggtgatcatgaatggttca
tgcgtagaagtagacgtgcatcggctgagtgacggagggctgctcctgtcttacgatggc
agcagttataccacatacatgaaggaggaagtggatagatatcgcatcacgatcggcaat
aagacctgtgtgtttgagaaggaaaatgacccttcggtgttgcgctcaccttctgctggg
aagttgatccagtacattgtggaggatggaggccatgtgtttgctggccagtgctatgcc
gagattgaggtgatgaagatggtaatgaccttaacagctgcagagtctggctgtatccat
tatgtcaaacggcctggaacagctcttgaccctggctgtgtgatagccaaaatgcagttg
gacaaccccagcaaggtccaacaggctgagcttcacacgggtagtctgccacggatccag
agcacagcactcagaggcgagaagctccaccgagtgttccactatgtcctggataatctg
gtcaacgtaatgaatggatactgccttccagatcctttttttagcagcagggtaaaagac
tgggttgagcggttgatgaagaccctcagagatccctccttgcctctgctagaattgcag
gatatcatgaccagtgtctctggccgtattccccccaatgtggagaagtctatcaagaag
gaaatggctcagtacgctagcaacatcacatcagtcctctgtcagtttcccagccagcag
atcgccaacaccctagatagccacgcggctacactgaaccggaaatccgagcgggaagtc
ttcttcatgaacactcagagcattgtccagctggtacagaggtaccgaagcggcatccga
ggccacatgaaggccgtggtgatggatctgctgcggcagtacctgcgagtagagacccag
ttccagaatggtcactatgacaaatgtgtgttcgcccttcgagaagagaacaagagtgac
atgaacactgtactgaactatatcttctctcacgctcaagtcaccaagaagaatcttctg
gtcacaatgcttattgaccagttgtgcggtcgggaccctactctcaccgacgagctgctg
aatatcctcacagagctaactcagctcagtaagaccaccaatgccaaagtggcgctccga
gcacgccaggttcttattgcgtcccatttgccatcatatgagcttcgccataaccaagta
gagtccatcttcctttcagcaattgacatgtatggacatcagttttgcattgagaacctg
cagaaactcatcttgtctgaaacatctatttttgacgtcctaccaaacttcttctatcac
agcaaccaggtagtgaggatggcagctctggaggtttatgttcgaagggcttatattgcc
tatgaacttaacagtgtacagcaccgccagcttaaggacaacacctgtgtggtggagttc
cagttcatgctgcccacctctcatccaaacagagggaacatccccacgctaaacagaatg
tccttctcctccaacctcaaccactatggcatgactcacgtagctagtgtcagtgatgtg
ctgttggacaactcattcactccaccatgtcagcggatgggcggaatggtctcttttcgg
acttttgaagattttgtcaggatctttgatgaagtgatgggctgcttctgcgattcccca
ccccaaagccccacgttccctgaggcaggtcacacatctctatacgatgaagacaaggtc
cccagggatgaaccaattcacattctgaatgtggctatcaagactgactgtgatattgag
gatgacggactggcagctatgttcagagagtttacccaacaaaacaaagctaccctggtt
gagcatggaatacggcgccttactttcctggttgcacaaaaggatttcaggaaacaggtc
aactgtgaggtggatcagagatttcatagagaatttcctaaatttttcaccttccgagcg
agggataagtttgaggaggatcgtatctaccgtcacctggaaccggccctggctttccag
ttagagctgaaccggatgagaaattttgaccttactgccattccatgtgctaaccataag
atgcacctgtatcttggggccgccaaggtggaagtgggcacagaagtgacagactacagg
ttcttcgttcgcgcaatcatcagacattctgatctggtcaccaaggaagcttcttttgaa
tatctacaaaatgaaggggagaggctgctcctagaagccatggatgagctggaagtcgct
tttaataatacaaatgttcgtacggactgcaaccacatcttcctcaactttgtgcccacg
gtcatcatggacccatcaaagattgaggaatctgtgcggagcatggtaatgcgctatgga
agtcggctgtggaaattacgtgtcctccaggcagagctgaaaatcaacattcgcctgaca
ccgactggaaaagcaattcccatccgcctcttcctgacaaacgagtctggctattacttg
gacatcagcttgtacaaggaagtgactgactccaggacagcacagatcatgtttcaggcg
tatggggacaaacagggaccactgcatggaatgttaatcaacactccatacgtcaccaaa
gacctgcttcaatcaaagagattccaggcacaatccttggggacaacatacatatatgat
atcccagagatgtttcgacagtctctgatcaaactctgggagtctatgtccactcaagca
ttccttccatcaccccctctgccttctgacatgctgacctatacggagctcgtgttggat
gatcaaggtcagctggtccacatgaacaggcttccaggaggaaatgagattggcatggta
gcttggaaaatgacccttaaaagtcctgaatacccagaaggccgagatatcattgttatt
gggaatgacatcacataccgaattgggtcctttgggccgcaggaggatttgctgtttctt
agagcttctgagcttgccagggcagagggtatcccacgcatctttgtagcagccaacagt
ggagcaagaattggactggcagaagaaattcgtcatatgtttcatgtggcctgggtagat
cctgaggatccttacaagggatacaaatatttatatctgacccctcaggattacaagaga
gtcagtgctctcaactctgtccactgtgaacatgtagaggacgagggagaatccaggtac
aagataactgatattattgggaaggaagagggacttggagtagagaaccttcgaggctct
ggaatgattgctggagaatcctcattggcctatgatgagatcatcaccatcagcctggtt
acatgccgggccattgggattggagcttaccttgtccggctgggacagagaaccatccag
gttgaaaattctcacttaattctgactggagccggggccctcaacaaagtccttgggcgg
gaggtatatacctccaataaccagctcgggggcatccagatcatgcacaacaatggggtg
acccacagcatcgtttgcgatgacttcgaaggggttttcactgtcctgcactggctgtct
tacatgccaaagagtgtgtgcagttcagttcctctcctgaactccaaggatcctatagat
agaatcatcgagtttgttcccacgaaggccccatatgatcctcgatggatgctagcaggc
cgacctcacccaacccagaaaggtcagtggttgagtggattttttgactatggatctttc
tcagagatcatgcagccctgggcccagactgtggtggtcggcagagccaggctaggagga
atacctgtgggagtagttgccgtagaaacccgaacagtggaactgagtatccccgctgat
cctgcaaacctggattctgaagccaagataatccagcaggctggccaggtttggttccca
gactctgcgtttaagacctatcaggctatcaaggacttcaaccgtgaagggctgcctctc
atggtctttgccaattggagaggcttctctggtgggatgaaagatatgtacgaccaagtg
ctgaagtttggtgcttacattgtggatagcttacgggagtgctcccagccggtgctggtg
tacattcctcctcaggctgagctccgggggggctcctgggttgtgatcgaccccaccatc
aacccccggcacatggagatgtatgctgaccgagagagcaggggatcagttctggagcca
gaggggacagtagaaatcaaattccgcagaaaggatctggtgaaaaccatgcgtcgggtg
gacccagtctacattcgcttggctgagcgattgggcaccccagagctaagcccagctgag
cggaaggagctggagaacaagttgaaggagcgggaggaattcctaattcccatttaccat
caggtagccgtgcagtttgctgacttgcacgacacaccaggccggatgcaggagaagggt
gttattaacgatatcctggactggaaaacatcccgtaccttcttctactggcggctgagg
cgtctcctgctggaggacctggtcaaaaagaaaatccacaatgccaacccagagctgacc
gatggccagattcaggccatgttacggcgttggtttgtagaagtggaaggaactgtgaag
gcctacgtttgggacaataacaaggatctggtggagtggctggagaagcagctgaccgag
gaagatggtgttcgctcagtaatcgaggaaaacatcaagtatatcagcagagactacgtc
ctgaagcagatccgcagcttggtacaggccaatcccgaggttgccatggactccatcgtt
cacatgactcagcacatctcacccacgcagcgagcagaagtcgtgcggatcctctccacc
atggactccccttcaacgtag
DBGET
integrated database retrieval system
