Ursus arctos (brown bear): 113271286
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Entry
113271286 CDS
T05909
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah00260
Glycine, serine and threonine metabolism
uah00630
Glyoxylate and dicarboxylate metabolism
uah00670
One carbon pool by folate
uah01100
Metabolic pathways
uah01200
Carbon metabolism
uah01230
Biosynthesis of amino acids
uah01240
Biosynthesis of cofactors
uah01523
Antifolate resistance
uah04981
Folate transport and metabolism
Module
uah_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
113271286 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
113271286 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
113271286 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
113271286 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
113271286 (SHMT1)
Enzymes [BR:
uah01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
113271286 (SHMT1)
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Gene cluster
GFIT
Motif
Pfam:
SHMT
DegT_DnrJ_EryC1
Motif
Other DBs
NCBI-GeneID:
113271286
NCBI-ProteinID:
XP_026376918
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All DBs
Position
Unknown
AA seq
484 aa
AA seq
DB search
MMTQVNGAPKDADLWSSHEKMLAQPLKDSDTEVYNIIKKESHRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELELLCQKRALQVYGLDPECWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
INYGQLEENARLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYLLADMAHISGLVAAGV
VPSPFEHCHVVSTTTHKTLRGCRAGMIFYRKGVRSVDPKTGKETLYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTPEFRLYQRQVVANCQVLAETLMELGYKVVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKEFQK
VAHFIHRGIELTLQIQNDVGAKATLKEFKEKLAGDEKHQRAVRALREEVESFASLFPLPG
LPDF
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atgatgactcaagtcaacggagctcccaaggatgccgacctgtggtcctcgcatgaaaaa
atgctggcgcagcccctgaaagacagtgacaccgaggtttacaacatcatcaagaaggag
agtcaccgccagagggtcgggctggagctgatcgcctccgagaatttcgccagccgagca
gttttggaggccctaggctcttgcttaaataacaagtactccgaggggtacccaggccag
aggtactatggcgggaccgagttcatcgacgagctggagctcctgtgtcagaagcgagcg
ctgcaggtctatggtctggaccccgagtgctggggggtcaatgtccagccctactcaggc
tcccctgccaacttcgcagtctataccgccctggtggagccccacgggcgcatcatgggc
ctcgacctgcccgacggcggccacctgacccacggcttcatgacggacaagaagaaaatc
tctgccacgtccatcttttttgaatctatgccctataaggtaaacccagacaccggctac
atcaactatggccaactggaggaaaacgcccgcctcttccacccgaagctgattatcgca
ggaaccagctgctactcccgaaacctggactacgctcgcctgaggaagatcgcggacgac
aacggggcgtatctcctggccgacatggcgcacatcagcgggctggtggcggctggtgtg
gtgccctccccctttgagcactgccacgtggtgtccaccaccacccacaaaactctgaga
ggctgccgggccggcatgatcttctacaggaaaggagtgcgcagcgtggatcccaagacc
ggcaaagagactctctacaacctggagtcgcttatcaactcggccgtgttcccgggcctg
cagggcggtccccacaaccatgccattgctggggtcgctgtggccctgaagcaagctatg
actccggaattccgactctaccaacgccaggtggtggccaactgccaggttctggctgag
accctgatggagctgggctacaaagtggtgacaggtggttctgacaaccatttgatcctt
gtggatctccgttccaaaggcacagatggtggaagggctgagaaggttctagaagcctgt
tctattgcctgtaataagaacacctgtccaggtgacaaaagcgcattgcggcccagcgga
ctgcgtctggggacgccagcactgacatcccgaggacttttggaaaaagagttccagaaa
gtagcccactttattcacagagggatagaactcactctgcagattcagaacgatgttggg
gccaaggccaccctgaaggagttcaaagagaaactggcaggggacgagaagcaccaaagg
gccgtcagggctctcagggaggaagtggagagcttcgcgtctctcttccctctgcctgga
ctgcctgacttctag
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