KEGG   Ursus americanus (American black bear): 123775502
Entry
123775502         CDS       T07931                                 
Symbol
INS
Name
(RefSeq) insulin
  KO
K04526  insulin
Organism
uar  Ursus americanus (American black bear)
Pathway
uar04010  MAPK signaling pathway
uar04014  Ras signaling pathway
uar04015  Rap1 signaling pathway
uar04022  cGMP-PKG signaling pathway
uar04066  HIF-1 signaling pathway
uar04068  FoxO signaling pathway
uar04072  Phospholipase D signaling pathway
uar04081  Hormone signaling
uar04114  Oocyte meiosis
uar04140  Autophagy - animal
uar04150  mTOR signaling pathway
uar04151  PI3K-Akt signaling pathway
uar04152  AMPK signaling pathway
uar04211  Longevity regulating pathway
uar04213  Longevity regulating pathway - multiple species
uar04810  Regulation of actin cytoskeleton
uar04910  Insulin signaling pathway
uar04911  Insulin secretion
uar04913  Ovarian steroidogenesis
uar04914  Progesterone-mediated oocyte maturation
uar04917  Prolactin signaling pathway
uar04923  Regulation of lipolysis in adipocytes
uar04930  Type II diabetes mellitus
uar04931  Insulin resistance
uar04932  Non-alcoholic fatty liver disease
uar04940  Type I diabetes mellitus
uar04950  Maturity onset diabetes of the young
uar04960  Aldosterone-regulated sodium reabsorption
uar05010  Alzheimer disease
uar05215  Prostate cancer
uar05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:uar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123775502 (INS)
   04014 Ras signaling pathway
    123775502 (INS)
   04015 Rap1 signaling pathway
    123775502 (INS)
   04066 HIF-1 signaling pathway
    123775502 (INS)
   04068 FoxO signaling pathway
    123775502 (INS)
   04072 Phospholipase D signaling pathway
    123775502 (INS)
   04022 cGMP-PKG signaling pathway
    123775502 (INS)
   04151 PI3K-Akt signaling pathway
    123775502 (INS)
   04152 AMPK signaling pathway
    123775502 (INS)
   04150 mTOR signaling pathway
    123775502 (INS)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    123775502 (INS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    123775502 (INS)
  09143 Cell growth and death
   04114 Oocyte meiosis
    123775502 (INS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    123775502 (INS)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    123775502 (INS)
   04910 Insulin signaling pathway
    123775502 (INS)
   04923 Regulation of lipolysis in adipocytes
    123775502 (INS)
   04913 Ovarian steroidogenesis
    123775502 (INS)
   04914 Progesterone-mediated oocyte maturation
    123775502 (INS)
   04917 Prolactin signaling pathway
    123775502 (INS)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    123775502 (INS)
  09149 Aging
   04211 Longevity regulating pathway
    123775502 (INS)
   04213 Longevity regulating pathway - multiple species
    123775502 (INS)
 09160 Human Diseases
  09162 Cancer: specific types
   05215 Prostate cancer
    123775502 (INS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    123775502 (INS)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    123775502 (INS)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    123775502 (INS)
   04940 Type I diabetes mellitus
    123775502 (INS)
   04950 Maturity onset diabetes of the young
    123775502 (INS)
   04932 Non-alcoholic fatty liver disease
    123775502 (INS)
   04931 Insulin resistance
    123775502 (INS)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:uar04052]
    123775502 (INS)
Cytokines and neuropeptides [BR:uar04052]
 Neuropeptides
  Unclassified
   123775502 (INS)
SSDB
Motif
Pfam: Insulin Ins_beta
Other DBs
NCBI-GeneID: 123775502
NCBI-ProteinID: XP_045626705
LinkDB
Position
Unknown
AA seq 109 aa
MALWTRLLPLLALLAFWAPVPARTFVNQHLCGSHLVEALYLVCGERGFFYTPKARREVED
LPVRDARPEGVPGADPQPRSLAGALQRRGIVEQCCTSICSLYQLENYCN
NT seq 330 nt   +upstreamnt  +downstreamnt
atggccctctggacgcgcctcctgcccctgctggctttgctggccttctgggcacctgtg
cccgccagaaccttcgtgaaccagcacctgtgtggctcccacctggtggaggcgctctac
ctggtgtgcggggagcgaggcttcttctacacgcccaaggcccgccgggaggtggaggac
ctgccggtgagggacgccaggccggaaggggtgcctggcgcagacccgcagccccggtcc
ctggcaggggcgctgcagaggcggggcatcgtggagcagtgctgcaccagcatctgctcg
ctctaccagctggagaattactgcaactag

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