Ursus americanus (American black bear): 123775561
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Entry
123775561 CDS
T07931
Symbol
HTT
Name
(RefSeq) huntingtin
KO
K04533
huntingtin
Organism
uar
Ursus americanus (American black bear)
Pathway
uar05016
Huntington disease
uar05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05016 Huntington disease
123775561 (HTT)
05022 Pathways of neurodegeneration - multiple diseases
123775561 (HTT)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
uar03019
]
123775561 (HTT)
04131 Membrane trafficking [BR:
uar04131
]
123775561 (HTT)
03029 Mitochondrial biogenesis [BR:
uar03029
]
123775561 (HTT)
Messenger RNA biogenesis [BR:
uar03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Common to processing body (P body) and stress granule
123775561 (HTT)
Membrane trafficking [BR:
uar04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
123775561 (HTT)
Mitochondrial biogenesis [BR:
uar03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
123775561 (HTT)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Htt_C-HEAT
Htt_N-HEAT
Htt_bridge
Htt_N-HEAT_1
HEAT
HEAT_2
HEAT_EF3_N
Motif
Other DBs
NCBI-GeneID:
123775561
NCBI-ProteinID:
XP_045626823
LinkDB
All DBs
Position
Unknown
AA seq
3129 aa
AA seq
DB search
MATLEKLMKAFESLKSFQQQQQQQQPPPLPPQPPQPPPQAQPPPPQPQPPPPPPPPPPPG
PAAAEEPLHRPKKELSATKKDRVNHCLTICENIVAQSLRNSPEFQKLLGIAMELFLLCSD
DAESDVRMVADECLNRVIKALMDSSLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLV
RPQKCRPYLVNLLPCLTRISKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIA
NLKSSSPTIRRTAAGSAVSICQHSRRTQYFYSWLLNVLLGLLVPVEGEHSTLLILGVLLT
LRYLVPLLQQQVKDTSLKGSFGVTRKELEVSPSTEQLIQVYELTLHYTQHQDHNAVTGAL
ELLQQLFRTPPPELLQALSTPGGGPLAAVHRQPGCRSRSGSIVELLAGGGSSCSPVLSRK
QKGKVLFGEAAALEDDSESRSEGSSPAFAASVKGEIGGELAASSGVSTPGSASSATDSVG
HDIITEQPRSQHTLQPDSADLTGCDLASAATDGDEEDILSHSSSQISAVPSDPAMDLNDG
TQASSPVSDSSQTTTEGPDSAVTPSDSSEIVLDGADSQYSGVQIGQPQDEDEEATGIHRD
EDADAFRNSSVALQQAHLLKSMGHSRQPSDSSVDKFVSRDEAAEPGDQENKPCRIKGDIG
QSTDDDSVPLVHCVRLLSASFLLTGEKNVLVPDRDVRVSVKALALSCVGAAVALHPESFF
SKLYKVPLDTVEYPEEQYVSDILSYIDHGDPQVRGATAVLCGTLISSILSRSRFQVGDWM
GTVRALTGNTFSLADCIPLLQKTLKDESSVTCKLACTAVRHCVMSLCSSSYSELGLQLIT
DMLTLRDSSYWLVRTELLETLAEIDFRLVSFLEAKAENLHRGAHHYTGLLKLQERVLHDV
VIHLLGDEDPRVRHVAAAALMRLVPKLFYKCDQGQADPVVAVARDQSSVYLKLLMHETQP
PSHFSVSTITRIYRGYNLLPNMTDVTVENNLSRVIAAVSRELVTSTTRALTFGCCEALCL
LSAAFPVCIWSLGWHCGVPPLSASDESRKSCTVGMATMILTLLSSAWFPLDLSAHQDALV
LAGNLLAASAPKSLRSSWTSEEEANPAAAKQEEVWPALGDRTLVPMVEQLFSHLLKVINI
CAHVLDDVAPGPAIKAALPSLTNPPSLSPIRRKGKEKEPGEPASVPLSPKKGSEASPASR
QSDAPGPVTANKSSSLGSFCHLPSYLKLHDVLKATHANYKVTLDLQNSTEKFGGFLRSAL
DVLSQILELATLQDIGKCVEEILGYLKSCFSREPVMATVCVQQLLKTLFGTNLASQFDGL
SSNPSKSQGRAQRLGSSSVRPGLYHYCFMAPYTHFTQALADASLRNMVQAEQDHDTSGWF
DVLQKVSTQLKTNLTSATKNRADKNAIHNHIRLFEPLVIKALKQYTTTTSVQLQRQVLDL
LAQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNIFFFLVLLSYERYHS
KQIIGIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGTNKADAGKELETQKEVV
VSMLLRLIQYHQVLEMFILVLQQCHKENEDKWKRLSRQIADVILPMLARQQMHIDSHEAL
GVLNTLFEILAPSSLRPVDMLLRSMFVTPDTMASVSTVQLWISGILAILRVLISQSTEDI
VLSRIQELSFSPYLISCPIINRLRDGDSTSTPEERNEGRQTKSLPEETFSRFLLQLVGIL
LEDIVTKQLKVEMSEQQHTFYCQELGTLLMCLIHIFKSGMFRRITAAASRLFTVDSADGS
FYGLERLNARVRAMVPTHPALVLLWCQILLLVSHTDYRWWAEVQQTPRRRSLSSTKSLSP
QMPGEEEGPDAACKLGMCNREIVRRGALILFCDYVCQNLHDSEHLTWLIVNHIQDLISLS
HEPPVQDFISAVHRNSAASGLFIQAIQSRCENLSAPTALKKTLQCLEGIHLSQSGAVLTL
YVDKLLCTPFRVLARMVDTLACRRVEMLLAANLQSSTAQLPVEELSRIQEYLQSSGLAQR
HQRLYSLLDRLRLATAPGSRGPSPPVTSHPLDGDGPLALETVTPDKDWYLRLVKSQCWTR
SDSALLEGAELVNRIPPSDMSTFMMNSEFNLSLLAPCLGLGMREISGGQRSPLFEAARLA
TLDRVTGLVQQLPAAHHVFQPFLPVEPTTYWSKLNDLFGDAVLYRSLTTLARALAQYLLV
FSKLPSHLHLPPEKERDTVKFVVMTLEALAWHLIHEQIPLSLDLQAGLDCCCLALQLPSL
WSVLSSPEMVTHACSLIHCVRFVLEAVVVQPGDQLLSPERRRNTPKASREDEVDSNTQNP
AYITAACGMAAEMVESLPSVLALGHKRNSSTPAFLTSVLRNIIISLARLPLVNSYTRVPP
LVWKLGWSPKPGGDFGTAFPEIPVEFLQEKEVFKEFIYRINVLGWTSRTQFEETWATLLG
VLVTQPLVMEQEESPPEEDTERTQINVLAVQAITSLVLSAMTVPVAGNPAVSCLEQQPRN
KPLKALDTRFGRKLSIIRGIVEQEIQAMVSKRENIATHHLYQAWDPVPSLSPATTGTLIS
HDKLLLQINPERELGNMSYKLGQVSIHSVWLGNSITPLREEEWEEEEEEEADVPVPASPP
TSPVNSRKHRAGVDIHSCSQFLLELYSRWILPSGSARRTPIILISEVVRSLLVVSDLFTE
RTQFEMMYLALTELRRVHPAEDEILVQYLVPATCKAAAVLGMDKAVAEPVSRLLESTLRS
SHLPSKVGALHGALYVLECDLLDETAKQLVPVISDYLLSNLKGVAHCVNIHSQQHVLVMC
ATAFYLIENYPLDVGPEFSASIIQMCGVMLSGSEESTPSIIYHCVLRGLERLLLSEQLCR
LDAESLVKLSVDRVNVHSPHRAMAALGLMLTCMYTGKEKISPGRSSDPSPAAPDSESVIV
AMERVSVLFDRVRKGFPCEARVVARILPQFLDDFFPPQDVMNKVIGEFLSNQQPYPQFMA
TVVYKVFQTLHSTGQSSMVRDWVMLSLSNFTQRTPVAMAVWSLSCFFVSASTSPWVSAVL
PHVISRMGKLEQVDVNLFCLVATDFYRHQIEEELDRRAFQSVFEVVAAPGNPYHRLLTCL
RNVHKVATC
NT seq
9390 nt
NT seq
+upstream
nt +downstream
nt
atggcgaccctggaaaagctgatgaaggccttcgaatccctcaagtccttccagcagcaa
cagcagcagcagcagcctccgccgctgccgcctcagcctcctcagccgccgccgcaggcg
cagccgccgccgcctcagccgcagccgccgccgcccccgccgcccccgccgccccccggc
ccggccgcggccgaggagcctctgcaccgaccaaagaaagaactctcagccaccaagaaa
gaccgcgtgaaccattgtctgacaatatgtgaaaacatagtggcccagtcactcagaaat
tctccagaatttcagaaacttctgggcatcgctatggaactttttctgctgtgcagtgat
gacgcagagtcggatgtccggatggtggctgacgagtgcctcaacagagtcataaaagcg
ctgatggactccagtcttccgaggttacagttagaactctataaggaaataaaaaagaac
ggtgctccccgcagcctgcgcgccgccctgtggaggtttgctgagctggctcacctggtc
cggcctcagaagtgcaggccttacttggtaaaccttttgccttgcctgactcgaataagc
aagagacctgaggaatctgttcaggagaccttggctgcagctgtacccaaaattatggct
tcttttggcaattttgcaaatgacaatgaaattaaggttctattaaaggctttcatagcg
aatctgaagtcaagctccccgaccattcggcggacggcagctggctcagcagtgagcatc
tgccagcactcgagaaggacgcagtacttttacagctggctactaaatgtgctcttaggc
ttgctggtccctgttgagggtgaacactccaccctcctgattcttggagtgctgctcacg
ttgaggtacctggtgcccttgctgcagcagcaggtcaaggacacgagcctgaaaggcagc
tttggggtgacacggaaagaactggaagtctccccctcgacagagcagctcatccaggtg
tatgaactgaccttgcactatactcagcaccaagaccacaatgctgtgaccggggcactg
gaactcctgcagcagctgttcaggacgcccccgcctgagctcctgcaggccctgagcacg
ccgggaggcgggcccctcgccgctgtgcaccgccagcccggctgccggagccgcagcggc
agtatcgtggagctgctagctggagggggttcttcatgcagccctgtcctttcaagaaaa
caaaaagggaaagtgctttttggagaagcagcagccttggaggacgactctgagtccagg
tcggagggcagcagccccgcctttgcagcctcagtcaagggtgagattggtggcgagctg
gccgcctcttccggggtctccactcctggctctgccagttcagccaccgactccgtgggg
cacgacatcatcaccgagcagccccggtcacagcacaccctgcagccagactcggcggat
ctgaccggctgtgacctggccagtgctgccaccgacggggacgaggaggacatcttgagc
cacagctctagccagatcagtgccgtcccgtccgacccggccatggacctgaacgatggc
acccaggcctcctccccagtcagcgacagctcccagaccaccaccgaggggcctgattca
gccgtgacaccttcagacagttctgaaattgtgttagatggtgccgacagccagtattcg
ggggtgcagatcggacagccgcaggacgaggatgaggaagccacgggcattcaccgggat
gaagacgcagatgcgttcagaaactcttcagttgcccttcagcaagcacatttattgaaa
agcatgggccacagcaggcagccctctgacagcagtgtagataaatttgtctccagagat
gaagctgctgagccaggagatcaagaaaacaagccttgccggatcaaaggtgacatagga
cagtctactgatgatgattctgtccctcttgtgcactgtgtccgccttctgtctgcttcg
tttttgctgaccggggaaaaaaatgtgttggttccggacagggacgtgagggtcagtgtg
aaggcgctggcactcagctgtgtgggagctgctgtggcccttcatcctgaatctttcttc
agcaaactttataaagtacctcttgacaccgtggagtaccctgaggagcagtacgtgtca
gacatcctgagctacatcgatcacggagacccccaggtcagaggagccacggccgttctg
tgtgggaccctcatctcctccatcctcagcaggtcccgcttccaagtgggagactggatg
ggcaccgtcagggccctgacaggaaatacattttctctggcggactgcattcctttgctg
cagaaaactttgaaggatgaatcttctgtgacttgcaagttggcttgtacagctgtgagg
cactgtgtcatgagtctctgcagcagtagctatagtgagctgggactacagctgatcacc
gacatgctgaccctgagggatagttcctactggctggtgaggacggagcttttggaaact
cttgcagagattgactttaggttggtgagctttttggaggcaaaagcagaaaacctgcac
agaggggcccatcattacacagggcttttaaaactgcaagaacgagtgctgcatgatgtc
gtcatccatctgctcggggacgaggaccccagggtgcggcacgttgctgcagcagcactg
atgaggcttgtcccgaagctgttttataagtgtgaccaaggacaagctgaccccgtcgtg
gctgtggcgagagaccaaagcagtgtttacctgaagctcctcatgcacgagacgcagcct
ccatctcacttctccgtcagcaccatcaccagaatatacagaggctataacttactgccg
aacatgacggatgtcaccgtggaaaacaacctctctcgggtcattgcggcggtttcccgc
gaactggtcacatccaccacacgcgcgctcacatttggatgctgcgaagctctgtgtctc
ctttcagccgccttccctgtctgcatttggagtttaggttggcattgtggggtgcccccg
ctgagcgcctccgatgagtcgagaaagagctgtactgtaggcatggccacaatgatcctc
accttgctctcatcagcttggttcccgctggatctctcagcccatcaggatgctttggtt
ttagccgggaacttgctcgcagccagtgcccccaaatctctcagaagttcgtggacctct
gaagaagaggccaacccagcagccgccaagcaggaagaggtctggccagctctgggtgac
cggaccctggtgcccatggtggagcagctcttttcccacctgctgaaggtgattaatatc
tgtgctcacgtcttggatgatgtggctcccggaccagcaataaaggcagccttgccgtct
ctgacaaaccctccttctctaagtcccatccgacggaagggaaaggagaaagaacccgga
gagccagcctctgtgcccttgagccccaagaaaggcagtgaagccagtccagcctctcga
caatctgacgccccagggcctgttacagcgaataagtcctcatcgctggggagtttctgt
caccttccttcatacctcaaattgcacgacgtcctgaaagctactcacgccaactacaag
gttaccttggatcttcagaacagcaccgaaaagtttgggggctttctgcgctctgccttg
gatgttctctctcagatcctagagctggcgacgctgcaggacatcgggaagtgtgtggag
gagatcctcgggtatctgaagtcctgtttcagtcgagaaccagtgatggcaactgtctgc
gtccagcagctgttgaagactctcttcgggacaaacttggcctcccagtttgatggctta
tcctccaaccccagcaagtctcaaggccgagcacagcgtctgggctcctccagcgtgagg
ccgggcttgtaccactactgcttcatggctccgtacacccacttcacccaggccttagcc
gacgccagcctgaggaacatggtgcaggcggagcaggaccacgacacctcagggtggttc
gatgtgcttcagaaggtatctacccagttgaagaccaacctcacgagtgccactaagaat
cgcgcggataagaatgctattcataaccacattcgtttgttcgagccgctggtcatcaaa
gctttaaagcagtacacgacgaccacgtccgtgcagctgcagaggcaggttttggacctg
ctggcccagctcgttcagttacgggtcaattactgtcttctggactcagaccaggtgttt
attggatttgtgctgaagcagtttgaatacattgaagtaggccagttcagggaatcagag
gcaattattccaaacatctttttcttcctggtattactgtcttacgaacgctatcattca
aaacagatcattggaattcctaaaatcattcagctctgtgatggcatcatggccagtggg
aggaaggctgtgacacatgccataccagctctgcagccaatagtccatgacctctttgta
ctgagaggaaccaataaagccgatgcaggaaaagagcttgaaacccaaaaagaggtggtg
gtatcgatgctgctgagactcatccagtaccatcaggtgttggagatgttcatcctggtc
ctgcagcagtgccacaaggagaacgaagacaagtggaagcgactgtctcggcagatagct
gatgtcatcctcccgatgttagccaggcagcagatgcacattgattctcatgaagccctt
ggagtgttgaatactttgtttgaaattctggccccttcctccctccgtcccgtggacatg
cttttacggagtatgtttgtcactccggacacaatggcatctgtgagcactgttcaactg
tggatctcaggaattctagccattttgagggttctgatttcccagtcaactgaagatatt
gttctttctcgtattcaggagctctccttctccccatatttaatctcctgtccaataatt
aataggttaagagatggggacagtacttcaacgccggaagaacgcaatgaagggagacaa
accaagagtttgccagaggaaacattttcaaggtttctgctacagctagttggcattctt
ttggaggatattgttacaaaacagctaaaagtggaaatgagcgagcagcagcatactttc
tattgtcaagagctgggcacgctgctaatgtgtctgatccacatcttcaagtctggaatg
ttccggagaatcacagcagctgcctctagactcttcacggtggacagcgccgacggcagt
ttctacggcctggagaggctgaatgcgcgggtgcgagccatggtgcccacgcacccggcc
ctcgtgctgctctggtgccagatcctgctgctcgtcagccacactgactaccgctggtgg
gcagaggtgcagcagacccccaggagacgcagtctgtccagtacgaagtcactcagcccc
cagatgcctggagaggaggagggtcccgatgcagcctgcaagcttgggatgtgcaataga
gaaatagtgcgaaggggagctctcattctcttctgcgattatgtctgtcagaacctacac
gattcagagcacctaacgtggctcatcgtgaatcatatccaggacctgatcagtctgtcc
cacgagccgcctgtgcaggattttattagcgctgttcatcggaactccgccgccagcggc
ctcttcatccaggcaattcagtctcgttgtgagaatctttcagcccccaccgccctgaag
aagacgctgcagtgcttggaagggatccacctgagccagtcgggcgctgtgttaacactg
tatgtggacaagctcttgtgcactccgttccgtgtgctggctcgcatggtcgacacccta
gcctgtcgccgggtggaaatgcttctggctgcaaatttacagagcagcacggcccagttg
ccagtggaggaactcagcaggatccaggagtaccttcagagcagcgggctggcccagaga
caccagaggctctattccctgctggacaggcttcgtctcgccaccgcaccaggctcacgt
ggcccttctcctccggtcacgtcccacccgctggacggggatgggcccctggcactggag
accgtgactccagacaaagactggtacctacgtctagtcaaatcccagtgctggactagg
tcagattctgcgctgctggaaggggcagagctggtgaatcggattcctcccagtgacatg
agtacattcatgatgaactcggagttcaacttaagcctgttggccccatgcctgggcctg
ggcatgcgtgaaatctccggaggccagaggagtcccctttttgaagcagctcgcctggcg
actctggaccgtgtgaccggcctggttcagcagctccctgccgcccaccacgttttccag
ccgttcctgcctgtggaacctaccacctactggagcaagctgaatgacctgtttggagat
gctgtgttgtatcggtccttgaccactctggcccgggccctggcccagtacctgctggtg
ttctccaaactgcccagtcatttgcacctccctcctgagaaggagagagacactgtgaag
tttgtggtcatgaccctcgaggccctggcatggcatctgatccatgagcagatcccactg
agtctggaccttcaggcaggcctggattgctgttgcctggccctgcagctgcccagcctc
tggagcgtgctgtcctccccggagatggtgacccacgcctgctctctcattcactgtgtc
cgcttcgtcctggaagccgttgtggtgcagcctggggaccagcttcttagtccagaaaga
aggaggaacactccaaaggcttccagagaggacgaagtggattcaaacacacaaaaccca
gcatatatcaccgcagcctgtgggatggcagcagaaatggtggagtctttgccgtcggtg
ttggccttggggcataaaaggaatagcagcacccctgcgtttctcacgtcggtgctcagg
aacatcatcatcagcttggctcgcttacccctcgtcaacagctacacgcgcgttcccccc
ttggtttggaagctcggatggtcgcccaagccgggaggggactttggcacagccttccct
gagatccctgtggagttcctccaggagaaggaagtctttaaagagttcatctaccgcatc
aatgtgctagggtggaccagccgcacccagtttgaggaaacgtgggccaccctccttggt
gtcctggtgactcagcccctggtgatggagcaggaggagagcccaccggaagaagacacg
gagaggacccagatcaatgtcctggccgtgcaggccatcacctcgctggtgctgagtgca
atgaccgtgcccgtggctggcaacccagctgtgagctgcttggagcagcagccccggaac
aaacccctgaaagccctcgacaccaggtttgggaggaagctgagcattatccgaggaatc
gtagagcaggaaatccaggcgatggtctcaaagagagagaacattgccacccatcactta
taccaggcgtgggaccccgtcccttctctgtctccagctacgacaggtaccctcatcagc
cacgacaagcttctgctgcagatcaaccccgagcgggagctggggaacatgagctataag
cttggccaggtgtccattcactccgtgtggctggggaacagcattacacccctgagagag
gaggagtgggaggaagaggaagaggaggaggccgatgtccctgtccctgcgtcaccaccc
acatcacccgtcaactccaggaagcaccgggctggggtcgatatccactcctgttcccag
tttttgcttgaactgtacagtcgctggatcctgccgtcagggtcagccagaaggaccccc
atcatcctgatcagcgaagtggttcgatctctcctggtggtctcagacttgttcactgag
cgcacccagtttgagatgatgtacctggcactgacggagctgcggagggtgcaccctgcg
gaggacgagatcctcgtgcagtacctggtgcccgccacctgcaaggcggccgccgtcctc
ggaatggacaaggccgtggcggagccggtgagccgactgctggagagcacgctgaggagc
agccacctgcccagcaaggtcggggccctgcacggcgctctctacgtgctggagtgcgac
ctcctggatgagacggcgaagcagctcgtcccagtcatcagcgactacctcctgtccaac
ctcaaaggggtagcccactgcgtgaacattcatagccagcagcacgtgctggtcatgtgt
gccactgccttctacctgatcgagaactaccctctggatgtaggcccagagttctctgca
tcaataatacagatgtgtggagtgatgctgtctggaagtgaggaatccaccccgtccatc
atctaccactgtgtcctgcggggcctagagcgtctcctgctctccgaacagctctgccgg
ctggacgcggagtcactggtcaagctgagtgtggaccgagtgaacgtgcacagcccacac
cgggccatggccgccctgggcctgatgctcacctgcatgtacacagggaaggagaaaatc
agtccgggcagaagctcagaccctagccccgccgccccggacagcgagtcagtgattgtg
gctatggagcgtgtgtctgtgctttttgacagggtcaggaaagggttcccctgtgaagcc
agagtggtggcacggatccttcctcagtttttagacgacttcttcccaccccaggacgtc
atgaacaaagtcattggtgaatttctgtccaaccagcagccgtacccgcagttcatggcc
actgttgtgtacaaggttttccagactctgcacagcaccgggcagtcgtccatggtccgg
gactgggtcatgctgtccctctccaacttcacgcagaggaccccagtggccatggccgtg
tggagcctctcctgcttctttgtcagcgcttccaccagcccgtgggtctcagccgtcctt
ccccatgtcatcagcaggatgggcaagctggagcaagtggacgttaaccttttctgcctg
gtggccacggacttttacagacaccagatagaggaggagctggaccgtcgggctttccag
tccgtgttcgaggtggtcgcggcaccaggaaacccatatcatcgattgctgacttgtttg
cggaacgtccacaaggtcgccacgtgctga
DBGET
integrated database retrieval system
