Ursus americanus (American black bear): 123775611 Help Entry 123775611         CDS       T07931                                  Symbol TSC1 Name (RefSeq) hamartin isoform X1   KO K07206   tuberous sclerosis 1 Organism uar  Ursus americanus (American black bear) Pathway uar04072   Phospholipase D signaling pathway uar04140   Autophagy - animal uar04150   mTOR signaling pathway uar04151   PI3K-Akt signaling pathway uar04152   AMPK signaling pathway uar04211   Longevity regulating pathway uar04218   Cellular senescence uar04714   Thermogenesis uar04910   Insulin signaling pathway uar05163   Human cytomegalovirus infection uar05165   Human papillomavirus infection uar05168   Herpes simplex virus 1 infection uar05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:uar00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     123775611 (TSC1)    04151 PI3K-Akt signaling pathway     123775611 (TSC1)    04152 AMPK signaling pathway     123775611 (TSC1)    04150 mTOR signaling pathway     123775611 (TSC1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     123775611 (TSC1)  09150 Organismal Systems   09149 Aging    04211 Longevity regulating pathway     123775611 (TSC1)   09159 Environmental adaptation    04714 Thermogenesis     123775611 (TSC1)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     123775611 (TSC1)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     123775611 (TSC1)    05165 Human papillomavirus infection     123775611 (TSC1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hamartin Motif Other DBs NCBI-GeneID:  123775611 NCBI-ProteinID:  XP_045626904 LinkDB All DBs Position Unknown AA seq 1190 aa AA seqDB search MAQQANLGELLSMLDSPVLSVRDEVTAVFKENLSSDRGPMLVNTLVDYYLETKSQPVLHI LTTLQEPHDKHLLDKMNDCMGRAASRLPALSLLGHVIRLQPPWKHKLSQAPLLPSLLKCL KVDTDVIVLTTGVLVLITMLPMIPQSGKQHLHDFFDIFGRLSSWCLKKPGHVTEIYLVHL HASVYALFHRLYGMYPCNFVSFLRSHYSMKENLDTFEEVVRPMMEHVRIHPELVTGSKDH ELDPRRWKRLETHDVVIECAKISLDPAEASYEDGDSVSPQVSARFPHRAADVAASPYVDM QNSCGSATSTPYSSSRLTLFSTPGQPPQTLSPPSTRLLTEPPQATLWSPSMVCGMTTPPT SPGNVPPDLSHPYSKVFGTTGGKGTPLGTPATSPPPAPLCHSDDYVHISLRQATATPPKK NDVGEKGWHQTVRCMPPSSLTCVFSLKEEKTDSARPCLHRQHHLPNDRGLEELPGSKGSV PLSDLPGFLGDLASEEDSIEKAKEEAAISKELSEITTAGTEPLVPRGGFDSPFYRDSLPG CPRKNHSAASGAQGASVNPEPLNSSLDKLGPDTPKQAFTPIDPPCGGANQSPAGSRERQT ALETDILTPSPCKIPPQRGVGFGSGQPPPYDHLFEVALPKTAHHFVSKKTKELLKKAKGN AEEDCPPSTSPAEVLDRLIQQGADAHSKELNKLSLPSKSVDWTHFGGSPPSDEIRTLRNQ LLLLHNQLLYERFKRQQHALRNRRLLRRVIRAAALEEHNAAMKDQLKLQEKDIQIWKVSM QKEQARYSQLQEQRDTMVTQLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRLEL KKANSKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQSKHSDTT KEVEMMKAACRKELEKNRSHVLQQNQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVK VQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLA SCKDGCSDSVTGHNEEASGHNGETKPPRPGGGARGGGASRGGGGGSELSTPEKPPTQRAG LFSSRWETTVGESATSIPTTVGSFPSSKSFLGMKARELFRNKSESQCDEDSVTISSLSET LKTELGKDPGAEAKTPLHLDGPQPSPPSPDSVGQLHIMDYDETHQEHSEG NT seq 3573 nt NT seq  +upstreamnt  +downstreamnt atggcccagcaagcaaacctcggggagctcctgtccatgctggactcccctgtgctgagt gtgcgcgacgaggtgacagctgtctttaaagagaacctcagctctgaccgtggtccgatg ctcgtaaacaccctggtggattattacctggaaaccaagtctcagccggtattgcacatc ctgactaccttgcaagagccgcacgacaagcacctcttggacaaaatgaatgactgtatg ggcagagccgcctctcggctgcccgcgctgtcgctgctggggcacgtcatcaggctgcag ccgccttggaagcacaaactctctcaagcacctcttttgccttctttactcaaatgtctc aaggtggacaccgatgtcatcgtcctcacgacaggtgtcttagtgttgataaccatgcta ccaatgattccacagtcggggaagcagcaccttcatgatttctttgatatttttggccgt ctttcatcgtggtgcctgaagaaaccaggccacgtgacagaaatctatcttgtccatctc catgccagtgtttatgctctctttcatcgcctctacggaatgtacccttgcaactttgtc tcctttctacgctctcactacagtatgaaggagaacttggacactttcgaagaagttgtc aggccaatgatggagcacgtgcggattcacccggaattagtgactggatccaaagaccac gaactggacccgcgaaggtggaagcgattagaaacacatgatgttgtcatagagtgtgcc aaaatctctctggaccccgccgaagcctcgtacgaagatggcgactccgtgtccccgcag gtgtcagcgcgctttcctcatcgtgcggctgatgtggccgccagcccttacgtcgacatg cagaatagctgtgggagtgctacctcgaccccttattccagctctcggctgacattgttc agtacacccgggcagccacctcagactctgagtcccccatcgacacggctgttgactgag ccgccacaagctactctttggagcccgtctatggtttgtggtatgaccactccgccaact tctcctggaaatgtcccacctgatctgtcacacccttacagtaaagtctttggtacaact ggtgggaaaggaactcctctgggaaccccagcaacgtctcctcctcccgccccgctctgc cactcagacgactacgtgcacatttccctccggcaggccacagccacaccccccaagaag aatgatgtgggggagaagggctggcaccagactgtccggtgcatgccgccttcttccttg acgtgtgtcttcagcttaaaggaagagaaaacagattcagcaaggccctgtctacacaga cagcaccatctcccgaacgacagaggattagaagagttacctggcagcaaaggttctgtc cctctgagtgaccttccagggtttttaggggacctggcctccgaagaagatagcattgag aaagctaaagaagaagcggcgatatctaaagaactctccgagatcacgacagccggcacc gagcccctggttcctcgaggaggctttgactcccccttctaccgggacagtctcccgggc tgccctcgcaagaaccattcggccgcctctggtgctcagggcgccagtgtgaaccctgag cctttaaactcctccctggacaagcttgggcctgacacaccgaagcaagcctttactccc atagacccgccctgtggaggcgccaaccagagccctgccgggagcagggagcgccagact gcgctggagaccgacatcctcactcccagcccttgtaaaattccgcctcagaggggagtg gggtttggaagtgggcagcctcccccttacgatcatctttttgaggtggcattgccaaag accgcccatcattttgtcagcaagaagaccaaggaactgttaaagaaagcaaaaggaaac gcagaggaagactgtcctccctcgacctcccccgcggaagtcctggacagactcatccag cagggagcagacgcgcacagcaaggagctgaacaagttgtccttacccagcaagtctgtc gactggacccactttggaggctctcctccctcagatgagatccgcaccctccgtaaccag ttgcttttactgcacaaccagttgctctatgagcgttttaagaggcagcagcacgcgctc cggaacaggcggcttctccgcagggtgatcagggcggcggccctggaggagcacaacgcg gccatgaaagaccagttgaagttacaagagaaggacatccagatctggaaggttagcatg cagaaggagcaggcccggtacagccagttgcaggagcagcgagacaccatggtcacccag ctccacagccagatccgccagctgcagcacgaccgggaggagttctacaaccagagccag gagctgcagacaaagctagaggactgcaggaacatgatcgcagagctgcgtctggaattg aagaaggccaacagcaaggtgtgtcacaccgagctgctgctcagtcaggtgtcccagaag ctctcaaacagtgagtcggtccagcagcagatggagttcttgaaccggcagctcttggtc cttggggaggtcaacgagttgtatctggaacaactgcagagcaagcactcagacaccaca aaggaggtagagatgatgaaagctgcgtgtcggaaagaactagaaaaaaacagaagccac gttctgcagcagaatcagaggctcgatacctcccagaaacggattttggaactggaatct cacctggccaagaaagaccaccttcttttggagcagaagaaatatttagaggatgtcaaa gtccaggcaagaggacagctgcaggcggcagagagcaggtatgaggctcagaaaaggatc acccaagtgtttgaattggagatcttagatttatacggcaggttggagaaggatggcctc ctgaagaaacttgaagaagaaaaagcagaagcggcagaagcggcagaagaaaggcttgcc tcttgcaaggacggctgctcggattctgtaacagggcacaacgaagaggcatctggccac aatggcgagaccaagcccccccgacccggcggtggcgcgcggggtggcggtgcgagtaga gggggtggcggcggcagcgagctttcgaccccggagaaaccccccacccagagggcaggc ctgttcagcagtcggtgggaaactaccgtgggagagtccgccaccagcatccccacgact gtcggctcctttcccagttcaaaaagcttcctaggcatgaaggcgcgagagttatttcgt aataagagcgagagccagtgtgacgaggacagtgtgaccatcagtagcctttctgagacg ctaaagacagaactgggcaaagacccgggtgcggaagccaagacccccctgcacctcgac ggcccacagccctcccccccgagcccggacagtgttggacagctgcacatcatggactac gacgagactcatcaggagcacagcgaagggtga

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