Ursus americanus (American black bear): 123775749
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Entry
123775749 CDS
T07931
Symbol
ABL1
Name
(RefSeq) tyrosine-protein kinase ABL1 isoform X1
KO
K06619
abelson tyrosine-protein kinase 1 [EC:
2.7.10.2
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar04012
ErbB signaling pathway
uar04014
Ras signaling pathway
uar04110
Cell cycle
uar04360
Axon guidance
uar04722
Neurotrophin signaling pathway
uar05200
Pathways in cancer
uar05206
MicroRNAs in cancer
uar05208
Chemical carcinogenesis - reactive oxygen species
uar05220
Chronic myeloid leukemia
uar05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
123775749 (ABL1)
04014 Ras signaling pathway
123775749 (ABL1)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
123775749 (ABL1)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
123775749 (ABL1)
09158 Development and regeneration
04360 Axon guidance
123775749 (ABL1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123775749 (ABL1)
05206 MicroRNAs in cancer
123775749 (ABL1)
05208 Chemical carcinogenesis - reactive oxygen species
123775749 (ABL1)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
123775749 (ABL1)
09166 Cardiovascular disease
05416 Viral myocarditis
123775749 (ABL1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uar01001
]
123775749 (ABL1)
Enzymes [BR:
uar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
123775749 (ABL1)
Protein kinases [BR:
uar01001
]
Non-receptor tyrosine kinases
ABL family
123775749 (ABL1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
F_actin_bind
SH2
SH3_1
SH3_2
SH3_9
Haspin_kinase
Kinase-like
SH3_6
Motif
Other DBs
NCBI-GeneID:
123775749
NCBI-ProteinID:
XP_045627234
LinkDB
All DBs
Position
Unknown
AA seq
1150 aa
AA seq
DB search
MGQQPGKVLGDQRRPSLPALHFIKGAGKKESSRHGGPHCNVFVEHEALQRPVASDFEPQG
LSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCE
AQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQR
SISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRN
KPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVE
EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLL
YMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKF
PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERP
EGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKKGVRGVAST
LLQAPELPTKTRTSRRAVEHKDPTDVPETPHSKGPGETDPLDHEPPVSPLLPRKERGPQD
GGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERKAASEEEGRET
SNGGPALTPSDTTEPAKSPKPSSGAGVPNGAFRETGGAGFRSPHLWKKSSTLTSSRLAAS
EEESGSSSSKRFLRSCSASCVPHGARDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPA
LPRKRASENRSDQVTRGTVTPPPRLVKKTEDAVDEVFRDTGESSPGSSPPSLTPKLLRRQ
VAGTPSSGLPHKDEAGKSGALGTPATAEPVPPASRAGPGASGGASKASTEEPRARRHKPS
SESPGRDKAKLSKLKPVPPPPPPASVGKAGKPSQNLSQEAAGEAGTGGKAKATAVVGDAV
NSDTIKPGPLGEGVKKPVLPSMPKPQSSSKPAGTPTSPAPTPSTVPSASSALAGDQPAST
AFIPLISTRVSLRKTRQPPERIASGTITKGVVLDGTEALCLAISKNSEQMASHSAVLEAG
KNLCTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATAGSGPAATQDFSKLLSS
VKEISDIVQR
NT seq
3453 nt
NT seq
+upstream
nt +downstream
nt
atggggcagcagcctggaaaagttcttggggaccagagaaggccaagtttgcctgccctg
cactttatcaaaggagcagggaagaaggaatcatcaaggcatgggggtccacactgcaat
gtttttgtggaacatgaagcccttcagaggccagtagcatccgactttgagccccaaggt
cttagtgaagcagctcgttggaactccaaggaaaaccttcttgctggccccagtgaaaat
gaccccaaccttttcgttgcactgtatgatttcgtggccagtggggacaacaccctaagt
ataactaaaggtgaaaagctccgggttttaggctacaatcacaatggggaatggtgtgaa
gcccaaaccaaaaatggccaagggtgggtcccaagcaactacatcacaccagtcaacagt
ctggagaaacattcctggtaccatgggcctgtgtcccgcaacgcggccgagtacctgctg
agcagtgggatcaacggcagcttcttggtccgagagagcgagagcagtcctggccagagg
tccatctcgctgagatacgaagggagggtgtaccactacaggatcaacactgcttccgat
ggcaagctctacgtctcctcagagagccgcttcaacactttggctgagctggttcatcat
cactcgactgtggcggacgggctcatcaccactctccattacccggcccccaagcgcaac
aagcccaccgtctacggcgtgtcccccaactacgacaagtgggagatggagcgcacggac
atcaccatgaagcacaagctgggaggaggccagtacggggaggtgtacgaaggcgtgtgg
aagaaatacagcctgacggtggccgtgaagaccttgaaggaggacaccatggaggtagaa
gagttcttgaaagaagctgcagtaatgaaagagatcaagcaccccaatctagtgcagttg
ctcggggtctgcacccgggaacccccattctatataatcactgagttcatgacctatggg
aacctgttggattacctgagagagtgtaaccggcaggaggtgaacgctgtggtgctgctg
tacatggccactcagatctcgtccgccatggagtacctggagaagaagaacttcatccac
agagatctcgctgcccgaaactgcctggtcggggagaaccacttggtgaaggtggctgat
ttcggcctgagcaggttaatgaccggggatacctacacggcccacgctggggccaagttc
ccgatcaagtggacggcgccagagagcctggcctacaataagttctccatcaagtccgac
gtctgggcttttggagtattgctttgggaaattgctacctatggcatgtcgccttaccca
ggaattgacctgtcccaggtgtatgagctgctagagaaggactaccgcatggagcgccca
gaaggctgcccggagaaggtctacgaactcatgcgagcatgttggcaatggaatccctct
gaccggccctcctttgctgaaatccaccaagcctttgagacaatgttccaggaatccagc
atatcagatgaagtggaaaaggaactggggaaaaaaggtgtgcgaggggttgcaagtact
ttgctgcaggccccagagctgcccaccaagacaagaacctccaggagagctgtggaacac
aaagaccccactgatgtgcctgagacaccccactccaagggcccgggagagaccgatcct
ctggaccatgagcctcctgtgtctccgctgctccctcgaaaagaacgaggtccccaggat
ggtggcctaaatgaagatgagcgccttctccccaaagacaaaaagaccaacttgttcagt
gccttgatcaagaagaagaagaaaacagccccaacccccccaaaacgcagcagctccttc
cgggaaatggacggccagcccgagcgcaaggcggccagtgaggaagagggccgagaaacc
agcaacggggggccagccctcacaccctcggacacaaccgagccagccaagtccccaaag
cccagcagcggggctggtgttcccaatggagccttccgggagacagggggtgcaggcttc
cggtctccccacctgtggaaaaagtccagtacactgaccagcagccgcctggcagccagt
gaggaagagagcggcagcagctccagcaagcgcttcctaaggtcttgctctgcctcctgc
gtgccccacggggccagggacacagagtggaggtctgtcacactgcctcgggatctgcag
tccacggggaggcaattcgactcgtccacgtttggagggcacaaaagcgagaagccagct
ctgcctcgaaagcgagcaagtgagaacagatctgaccaggtgaccagaggcacagtgact
cccccgcctaggctggtgaaaaagaccgaggatgcagtggacgaggtcttccgagacacg
ggggagtccagcccaggctccagccctcccagtctgactccaaaactcctccgcaggcag
gtcgcggggactccttcctcgggccttccccacaaggatgaggctgggaagtccggtgcc
ttggggacacctgccacagctgagccggtgccccccgccagcagagcagggccaggcgcg
tctggaggggccagcaaggcctccaccgaggagcccagagcaaggaggcacaagccttcc
tccgagtccccagggagagacaaggcgaaactgtccaagctcaaacctgtcccgccgccc
ccgccaccagcctccgttgggaaagccgggaagccctctcagaacctgagccaggaagca
gctggggaggccggcactggtgggaaagccaaagccacggctgtggttggggatgctgtg
aacagtgacaccatcaagcccggtccgctgggagagggtgtcaaaaagcccgtgctcccg
tccatgccaaagccacagtcgtccagcaagccggcggggaccccaaccagcccagctccc
accccttccaccgtgccgtcagcatcctctgccctggccggggaccagccagcctccact
gccttcattcctctcatatcaactcgtgtgtctcttcggaaaacccgccagcctccggag
cggatcgccagtggcaccatcaccaagggcgtggtcctggacggcacggaggctctgtgc
ctggccatctccaagaactccgagcagatggccagccacagcgccgtgctagaagccggc
aagaacctctgcacgttctgcgtgagctatgtggattccatccagcaaatgaggaacaag
ttcgccttccgcgaggccatcaacaaactggagaataatctccgggagcttcagatttgc
ccagcgacagcagggagtggcccggcggccactcaggacttcagcaagctcctcagctcc
gtgaaagagatcagtgacatcgtgcagaggtag
DBGET
integrated database retrieval system
