Ursus americanus (American black bear): 123775802
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Entry
123775802 CDS
T07931
Symbol
PLA2G4E
Name
(RefSeq) cytosolic phospholipase A2 epsilon isoform X1
KO
K16342
cytosolic phospholipase A2 [EC:
3.1.1.4
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar00564
Glycerophospholipid metabolism
uar00565
Ether lipid metabolism
uar00590
Arachidonic acid metabolism
uar00591
Linoleic acid metabolism
uar00592
alpha-Linolenic acid metabolism
uar01100
Metabolic pathways
uar04010
MAPK signaling pathway
uar04014
Ras signaling pathway
uar04072
Phospholipase D signaling pathway
uar04217
Necroptosis
uar04270
Vascular smooth muscle contraction
uar04370
VEGF signaling pathway
uar04611
Platelet activation
uar04664
Fc epsilon RI signaling pathway
uar04666
Fc gamma R-mediated phagocytosis
uar04724
Glutamatergic synapse
uar04726
Serotonergic synapse
uar04730
Long-term depression
uar04750
Inflammatory mediator regulation of TRP channels
uar04912
GnRH signaling pathway
uar04913
Ovarian steroidogenesis
uar04921
Oxytocin signaling pathway
uar05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
123775802 (PLA2G4E)
00565 Ether lipid metabolism
123775802 (PLA2G4E)
00590 Arachidonic acid metabolism
123775802 (PLA2G4E)
00591 Linoleic acid metabolism
123775802 (PLA2G4E)
00592 alpha-Linolenic acid metabolism
123775802 (PLA2G4E)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
123775802 (PLA2G4E)
04072 Phospholipase D signaling pathway
123775802 (PLA2G4E)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
123775802 (PLA2G4E)
04664 Fc epsilon RI signaling pathway
123775802 (PLA2G4E)
04666 Fc gamma R-mediated phagocytosis
123775802 (PLA2G4E)
09152 Endocrine system
04913 Ovarian steroidogenesis
123775802 (PLA2G4E)
04921 Oxytocin signaling pathway
123775802 (PLA2G4E)
09156 Nervous system
04724 Glutamatergic synapse
123775802 (PLA2G4E)
04726 Serotonergic synapse
123775802 (PLA2G4E)
04730 Long-term depression
123775802 (PLA2G4E)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
123775802 (PLA2G4E)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
123775802 (PLA2G4E)
Enzymes [BR:
uar01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
123775802 (PLA2G4E)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
cPLA2_C2
PLA2_B
C2
Motif
Other DBs
NCBI-GeneID:
123775802
NCBI-ProteinID:
XP_045627316
LinkDB
All DBs
Position
Unknown
AA seq
863 aa
AA seq
DB search
MTLQSSEGCPGLGTDVFIPQSLQEAEEDSRSERNVSEFELPQDPEPPNLPPLLPMAPWGS
QGGLSPCHLLTVKVIRMKNVRQADRVSQTDCFVSLWLPTASHERLRTRTISNCPNPEWNE
TFSFQIQSQVKNVLELSVCDEDTLTPDDHLLTILYDLTKLCFRKKTHVKFPLNPEGMEEL
EVEFLLEESPSPPESLITNGVLVSRQVSRLEVHAECRRRRKSRQMKDLLVTVKESFEHTQ
RVSCCQEPCPPNPACFHYPKYFQPCMHVDVPKSQCSRGLCCCCAHRKNSPVRQPLDCLPD
GQTVTLPVGENCELHMKSTPCPQTLDVRLGFSLCPAEQEFLQKRKPVVAQALQEVLQLEA
DLPVDEVPLIAIMATGGGTRSMTAMYGHLLGLQKLNLLNCASYITGLSGATWTMATLYCD
PDWSSKNLEPAIFEARRHVVKDKMPALFPDQLSKFQEELRQRSQEGYKVTFTDFWGLLIE
ACLGDERNESKLSDQRAALCQGQNPLPIYLTINVKDDVSNQDFREWCEFSPYEVGLQKYG
AFIPTELFGSEFFMGRLMKRIPESRMCYMLGLWSSIFSLNLLDAWNLSQSSEEFFHRWTR
ERVHDIEDEPLLPEIPKCDANVLDTAVVIPGSWLSNTFRSILTHRAFVSQFHNFLLGLQL
HTDYLQNSQFSMWRDTVLDGFPNQLTESVNHLCLLDTAFFVNSSYPPLLRPERKVDLIIH
LNYCAGSQTKPMKQTCEYCTVQNIPFPKYELQEDEDSLKECYLMENPQEPDAPIVLFFPL
INDTFQKYKAPGVERSPEELEQGHVDIYGPKTPYATKELTYTEAAFDKLVKLSEYNILNN
KDKLLQALRLAVEKKRLKSQCPS
NT seq
2592 nt
NT seq
+upstream
nt +downstream
nt
atgactctccagagctcggaaggctgtcctggcctgggaactgacgtgttcatcccccag
agcctgcaagaggctgaagaagacagcaggtcagaaagaaatgtcagtgagttcgagctg
ccacaggacccagaacctcctaatctcccacctctgcttcccatggccccttggggctct
cagggcgggctgtctccatgccacctgctgaccgtgaaggtcatccggatgaaaaacgtc
cgacaggctgatagggtgagccagacagactgctttgtgagcctctggctgcccaccgct
tctcatgagaggttgaggactaggaccatctccaactgtccgaacccagagtggaatgaa
accttcagcttccagatccagagccaagtgaagaacgtgctagagctgagcgtctgtgat
gaagacacactgaccccagatgaccatctcttgacaatcctctatgacctcaccaaactc
tgcttccggaagaaaacccacgtgaagttcccactcaacccagagggcatggaagagctg
gaggtggagttcctgctggaggagagtccctctccacctgagagcctcatcaccaatggc
gtgctggtgtctcggcaagtctcccgcctggaggttcatgcagaatgcaggaggcggagg
aagagcaggcaaatgaaggacctcctggtgacagtgaaggagtccttcgagcacacccaa
cgcgtctcgtgctgccaggagccctgccccccaaacccagcctgcttccactaccccaag
tacttccagccctgcatgcacgtggacgtgcccaagagccagtgcagccgtgggctttgc
tgctgctgtgcacacaggaagaacagccctgtccgccagccccttgactgcctccccgat
ggccagaccgtcaccctgccggtgggcgagaactgtgaattacacatgaagtctacaccc
tgcccacagacgctggacgtgcggctgggcttcagcctgtgcccggcagagcaggagttc
ctgcagaagcggaagccggtggtggcgcaggcgctgcaggaggtgttgcagctggaggcc
gacctgcctgtggacgaggtgccgctgatagccatcatggcgacggggggcggaacgaga
tccatgaccgccatgtacggccacctgctggggctgcagaagctgaacctcctgaactgt
gccagctacatcactggcctgtccggggccacctggaccatggcgaccttatactgtgac
cccgactggtcctccaaaaacctggagcccgccatatttgaggcacggaggcatgtggtc
aaggacaagatgcctgccctgtttccagaccagctgtccaaattccaggaggagcttcgg
cagcgcagccaggaaggctacaaggtcacctttacagatttctggggcctgctgattgag
gcctgtctgggggatgagagaaatgaatccaaactgtcagatcagcgtgctgctttgtgc
cagggccagaaccccctgcccatctacctcaccatcaatgtcaaggatgatgtaagcaac
caggatttcagagagtggtgcgagttctccccctacgaggtgggcctgcagaagtacggg
gccttcatccccaccgagctcttcggctccgagttcttcatggggcggctgatgaagagg
atcccagagtcgcgaatgtgctacatgctaggcttgtggagcagtatcttctcactaaac
ttgcttgatgcctggaatctgtcccaaagctcggaggagtttttccacaggtggacgagg
gagagagtgcatgatatcgaagatgagcccctcctgcctgaaatccccaaatgtgatgcc
aacgtcttggacactgcggtggtgatcccggggtcgtggctgtccaatactttccgcagc
atcctcacgcaccgggccttcgtgtcccagttccacaacttcctgttggggctgcagctg
cacaccgactacctccagaacagccagttctccatgtggagagacacggtgctagatggt
ttcccgaaccagctgacagagtccgtgaaccacttgtgcctgttggacactgcgttcttc
gtcaactccagctacccgcccctccttaggcccgagagaaaagtcgacctcatcattcac
ctcaattactgcgctgggtcccagacaaagccaatgaaacaaacatgtgagtactgcacc
gtgcagaacatccccttccccaaatacgagctgcaagaggacgaggacagcctcaaggag
tgctacttgatggagaacccccaggagcctgatgcccccatcgtgcttttcttcccactc
atcaacgacaccttccagaagtacaaggccccaggtgtggagcgaagccccgaggagctg
gaacagggccacgtggacatttatggccccaaaactccatacgctaccaaggagctgaca
tacacagaggctgcctttgacaagctggtgaagctctctgagtacaacatcctgaataac
aaggacaagctccttcaggccttgagactggcggtggagaagaaacgtctgaagagccag
tgtccctcctaa
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