Ursus americanus (American black bear): 123776440
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Entry
123776440 CDS
T07931
Symbol
SYK
Name
(RefSeq) tyrosine-protein kinase SYK isoform X1
KO
K05855
spleen tyrosine kinase [EC:
2.7.10.2
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar04064
NF-kappa B signaling pathway
uar04072
Phospholipase D signaling pathway
uar04151
PI3K-Akt signaling pathway
uar04380
Osteoclast differentiation
uar04611
Platelet activation
uar04613
Neutrophil extracellular trap formation
uar04625
C-type lectin receptor signaling pathway
uar04650
Natural killer cell mediated cytotoxicity
uar04662
B cell receptor signaling pathway
uar04664
Fc epsilon RI signaling pathway
uar04666
Fc gamma R-mediated phagocytosis
uar05152
Tuberculosis
uar05167
Kaposi sarcoma-associated herpesvirus infection
uar05168
Herpes simplex virus 1 infection
uar05169
Epstein-Barr virus infection
uar05171
Coronavirus disease - COVID-19
uar05203
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
123776440 (SYK)
04072 Phospholipase D signaling pathway
123776440 (SYK)
04151 PI3K-Akt signaling pathway
123776440 (SYK)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
123776440 (SYK)
04613 Neutrophil extracellular trap formation
123776440 (SYK)
04625 C-type lectin receptor signaling pathway
123776440 (SYK)
04650 Natural killer cell mediated cytotoxicity
123776440 (SYK)
04662 B cell receptor signaling pathway
123776440 (SYK)
04664 Fc epsilon RI signaling pathway
123776440 (SYK)
04666 Fc gamma R-mediated phagocytosis
123776440 (SYK)
09158 Development and regeneration
04380 Osteoclast differentiation
123776440 (SYK)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
123776440 (SYK)
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
123776440 (SYK)
05168 Herpes simplex virus 1 infection
123776440 (SYK)
05167 Kaposi sarcoma-associated herpesvirus infection
123776440 (SYK)
05169 Epstein-Barr virus infection
123776440 (SYK)
09171 Infectious disease: bacterial
05152 Tuberculosis
123776440 (SYK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uar01001
]
123776440 (SYK)
Enzymes [BR:
uar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
123776440 (SYK)
Protein kinases [BR:
uar01001
]
Non-receptor tyrosine kinases
SYK family
123776440 (SYK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
Kdo
DUF7063
ABC1
SH2_1
RIO1
Motif
Other DBs
NCBI-GeneID:
123776440
NCBI-ProteinID:
XP_045628365
LinkDB
All DBs
Position
Unknown
AA seq
635 aa
AA seq
DB search
MAGNTADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKA
HHYTIEREMNGTYAIAGGRTHSSPAELCLYHSQESDGLVCVLKKPLHRPPGVQPKTGPFE
DLKESLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISRVESEQI
VMIGSKTNGKFLIRDRNDNGSYALCLLHEGKVLHYRIDKDKTGKLSIPDGKKFDTLWQLV
EHYSYKPDGLLRVLTVPCQKIGGQTGNINFGARAPLPGAHPATWSAGAIISRIKSYSFPK
PGHRKASSSTGNRPESSVTFNPYEPDRGPWATDRDAQREAMPMDTEVYESPYADPEEIRP
KEVYLDRKLLTLEDSELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
GMKYLEECNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADESYYKAQTHGKWPVKWYA
PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVSAMLEKGERMGCPAGCPRE
MYELMKLCWTYEVEKRPGFENVELRLRNYYYDVVN
NT seq
1908 nt
NT seq
+upstream
nt +downstream
nt
atggcgggaaacacggccgacagcgccaaccacctgccattcttcttcggcaacatcacg
cgggaggaggcggaggactacctggtgcaggggggcatgagcgacgggctgtacctgctg
cgtcagagccgcaattacctgggcggcttcgcgctgtcggtggcgcacgggaggaaggcg
caccactacaccatcgagcgcgagatgaacggcacctacgccatcgcgggcggcaggacg
cacagcagcccggccgagctgtgcctctaccattcccaggagtccgacggcctcgtctgc
gtcctcaagaagcccctccaccggccgcccggggtgcagcccaagaccggcccattcgag
gacctgaaggagagcctcatcagggagtacgtgaagcagacctggaacctgcagggtcag
gctctggagcaggccatcatcagccagaagcctcagctggagaagctgatcgccaccacg
gcccacgagaaaatgccctggttccacgggaaaatctcacgggttgaatctgagcaaatt
gtcatgataggatccaagacaaacggaaaatttttgatcagggacaggaacgacaacggg
tcttacgccctgtgcctgctgcacgaggggaaggtgctgcactatcgcatcgacaaggac
aaaaccgggaagctctccatccccgacgggaagaagttcgacacgctctggcagctcgtg
gagcattactcttacaaaccggacgggctgttgagagttcttacagttccgtgccagaaa
attggcgggcagacaggaaacatcaactttggagcccgcgcgcccctgccaggtgcccac
cctgcgacgtggtcagcaggcgcgataatctccagaatcaaatcctactccttcccaaag
cccggccacagaaaggcctcctcgtccacagggaaccggcccgagagctccgtgaccttc
aatccttatgagccagaccgggggccctgggccacggacagagacgcgcagagagaagcc
atgcccatggacaccgaggtgtatgaaagcccctacgccgaccccgaggagatcaggccc
aaggaggtctacctggaccgcaagctgctgaccctggaggacagtgagctgggctctggg
aacttcgggaccgtgaagaagggctactaccagatgaaaaaagtcgtgaagacagtggct
gtgaagattctgaagaacgaggccaatgaccctgctcttaaagacgagttattagcagag
gcgaacgtcatgcagcagctcgataacccttacatcgtgcgcatgatcgggatatgtgaa
gccgagtcctggatgctggtcatggagatggcggaactggggccactcaataaatactta
cagcagaacaggcacgtcaaggataagaacatcatagagctggttcatcaggtttctatg
ggaatgaaatatctggaggagtgcaattttgtgcacagagatctggctgcaagaaacgta
ttgctggttactcaacattatgccaagattagtgatttcggactttccaaagcactccgt
gctgacgaaagctactataaggcccagacccacgggaagtggccggtgaagtggtacgct
ccggagtgcattaactactacaagttctccagcaagagcgacgtctggagctttggcgtg
ctgatgtgggaggcgttctcctacggccagaagccctaccggggcatgaaaggaagtgaa
gtttcggctatgctggagaaaggggagaggatggggtgccccgcgggatgtccgagggag
atgtacgagctgatgaagctgtgctggacatatgaggtggagaagaggcccggcttcgaa
aacgtggagctgcgtctgcgcaattactactatgacgtggtgaactaa
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