Ursus americanus (American black bear): 123776978
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Entry
123776978 CDS
T07931
Symbol
NOS2
Name
(RefSeq) nitric oxide synthase, inducible isoform X1
KO
K13241
nitric-oxide synthase, inducible [EC:
1.14.13.39
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar00220
Arginine biosynthesis
uar00330
Arginine and proline metabolism
uar01100
Metabolic pathways
uar04020
Calcium signaling pathway
uar04066
HIF-1 signaling pathway
uar04146
Peroxisome
uar04371
Apelin signaling pathway
uar04926
Relaxin signaling pathway
uar05010
Alzheimer disease
uar05014
Amyotrophic lateral sclerosis
uar05022
Pathways of neurodegeneration - multiple diseases
uar05133
Pertussis
uar05140
Leishmaniasis
uar05142
Chagas disease
uar05145
Toxoplasmosis
uar05146
Amoebiasis
uar05152
Tuberculosis
uar05200
Pathways in cancer
uar05222
Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
123776978 (NOS2)
00330 Arginine and proline metabolism
123776978 (NOS2)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
123776978 (NOS2)
04066 HIF-1 signaling pathway
123776978 (NOS2)
04020 Calcium signaling pathway
123776978 (NOS2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
123776978 (NOS2)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
123776978 (NOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123776978 (NOS2)
09162 Cancer: specific types
05222 Small cell lung cancer
123776978 (NOS2)
09171 Infectious disease: bacterial
05133 Pertussis
123776978 (NOS2)
05152 Tuberculosis
123776978 (NOS2)
09174 Infectious disease: parasitic
05146 Amoebiasis
123776978 (NOS2)
05145 Toxoplasmosis
123776978 (NOS2)
05140 Leishmaniasis
123776978 (NOS2)
05142 Chagas disease
123776978 (NOS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
123776978 (NOS2)
05014 Amyotrophic lateral sclerosis
123776978 (NOS2)
05022 Pathways of neurodegeneration - multiple diseases
123776978 (NOS2)
Enzymes [BR:
uar01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
123776978 (NOS2)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
123776978
NCBI-ProteinID:
XP_045629328
LinkDB
All DBs
Position
Unknown
AA seq
1157 aa
AA seq
DB search
MACPWQLLFKAKSYRFDLTEETDINNNVGKASQAPSSLVTQDDPKCHSLGKHRNESPQSL
TGTVKTSPESLIKLDSPPSACPRHVRIKNWGSGMTFQDTLHHKAKGDIACKSKSCLGAIM
NPKSLTRGPRNKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQ
LTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAKEMFEHICRHLRYATNNGNI
RSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGTILGDPASVEFTQLCIDLGWKPKYS
RFDVVPLVLQADGQDPEFFEIPPDLVLEVPMEHPKYEWFRELQLKWYALPAVANMLLEVG
GLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDRAVVEINV
AVLHSFQKRNVSIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPISGSITPVFHQEM
LNYVLSPFYYYQVEAWKTHTWQDEKRRPRRRKIPFKVLVKAVLFSAMLMRKTMASRVRAT
ILFATETGKSETLARDLGALFSCAFNPKVLCMDEYRLRHLEDEQLLLVVTSTFGNGDSPG
NGEKLKKSLFLLKELTNKFRYAVFGLGSSMYPQFCAFAHDIDQKLSHLGASQLAPTGEGD
ELSGQEEAFRSWAVQTFKAACETFEVQGKHRIQIPRLYTCNVTWDPQHYRLVQDSQPLDL
ERALSSMHAKKVFTLRLKSQRNLQSPQSSRTTLLVELSCEDSRGLSYLPGEHLGVCPSNQ
LALVQGILERVVDGPSPHQPVHLEILSENGSYWVRDKRLPPCSLSQALTHFLDITTPPTP
LLLRKLAQLATEEAERQRLETLCQPSEYNKWKFINSPTFLEVLEEFPSLRVSAGFLLSQL
PILKPRYYSISSSRDRTPTEVHLTVAVLTYRTRDGQGPLHHGVCSTWLSSLKPQDPVPCF
VRSASNFQLPEDPSHPCILIGPGTGIAPFRGFWQQRLHDTKYKGLQAGRMTLVFGCRRPD
EDHLYREEMLEMAQNGVLHEVHTAYSRLPCQPKVYVQDILRQRLASEVLRVLHEEHGHLY
VCGDVRMARDVAHTLKLLVAAKLRLSEEQVEDYFFQLKSQKRYHEDIFGAVFPYEVKKDG
AAKQPSDPKVTTAYGRS
NT seq
3474 nt
NT seq
+upstream
nt +downstream
nt
atggcctgtccctggcagctcctgttcaaggccaaatcctaccggttcgacttgaccgag
gaaacagacatcaacaacaatgtggggaaagccagccaggccccctccagtctagtgaca
caggatgaccccaagtgtcacagcctcggcaagcaccggaatgagtccccccagtcgctc
acagggacagtaaagacgtctccagaatccctgatcaagctggattcacccccatcggcc
tgcccgcggcatgtgaggatcaaaaactggggcagtggaatgaccttccaagacacactt
caccataaggccaaaggggatatcgcttgcaagtccaagtcttgtctgggagccatcatg
aaccccaaaagtttgaccagaggacccaggaacaagcctacccccccagacgagcttctg
cctcaagctattgaatttgtcaaccaatattatggttccttcaaagaagcaaaaatagag
gaacatctggccagggtggaagcggtaacaaaggagatagaaacaacaggaacctatcag
ctgacgggggatgagctcatcttcgccaccaagcaggcctggcgcaacgctccccgctgc
atcgggaggatccagtggtccaacctgcaggtcttcgacgcccggagctgttccactgcc
aaggaaatgttcgagcacatctgcagacacctgcggtatgccaccaacaacggcaacatc
aggtcggccatcaccgtgttcccccagcggagcgatgggaagcatgacttccgggtctgg
aacgctcagctcattcggtatgccggctaccagatgcctgatggcaccatcctgggggac
cccgccagcgtggagtttacccagctgtgcatcgacctgggctggaagcccaagtacagt
cgcttcgacgtggtgcccctggtgctgcaggcggatggccaagatccggagttcttcgaa
atcccacctgaccttgtgctcgaggtgcccatggaacatcccaagtacgagtggttccgt
gagctccagctgaagtggtacgccctgcccgcagtggccaacatgctgcttgaggtgggc
ggcctcgagttcccggggtgccccttcaacggctggtacatgggcacggagatcggggtc
cgggacttctgtgacgttcagcgttacaacattctggaggaagtgggcagaaggatgggc
ctggaaacgcacaagctggcctcactctggaaggaccgggctgtcgttgagatcaatgtt
gctgtgctccacagtttccagaagcggaatgtgagcatcatggaccaccactcagctgca
gagtcgttcatgaagtacatgcagaacgagtaccgttcccgagggggctgcccggccgac
tggatttggctggtccccccgatttctgggagcatcactcctgtgttccaccaggagatg
ctaaactatgtcctgtcccctttctactattaccaggtggaagcctggaaaacccacacc
tggcaggatgagaagcggagaccccggagaagaaagattccattcaaagtcttggtgaaa
gctgtgctcttctccgccatgctgatgcgcaagaccatggcttcccgagtcagagccaca
atcctctttgcaacggagacaggaaagtcagaaacgctggcccgggacctgggggccttg
ttcagctgcgccttcaaccccaaggttctctgcatggacgagtataggctgcgccatctg
gaggacgagcagctgctcctggtggtgaccagcacgtttgggaatggagactcccctggc
aacggagagaaactgaaaaaatctctcttcttgctgaaagagcttaccaacaagttcagg
tatgccgtgttcggcctcggctccagcatgtaccctcagttctgtgcctttgctcatgac
atcgaccagaagttgtcccatctgggggcctctcagctcgccccaacaggggaaggggac
gagctcagtgggcaggaggaagccttccgcagctgggccgtgcaaacctttaaggcggcc
tgtgagacgttcgaggtgcaaggcaaacaccgcattcagatccccaggctctacacctgc
aacgtgacatgggacccacagcactacaggctcgtgcaggactcacagcctctggacctc
gagagagccctcagcagtatgcacgccaagaaggtgttcaccctgaggctgaaatcacag
cggaatctacagagtccccagtccagccgcaccaccctcctggtggagctctcctgtgag
gacagccgcgggctgagctacttgcctggagagcacctcggggtttgccccagcaaccag
ctggccctggtgcaaggcatcttggaaagagtggtagacggcccctcaccccaccagcct
gtgcacctggagatcctcagtgagaacggaagctactgggtcagagataagcggctgccc
ccgtgctcactcagccaggccctcacccacttcctggacatcaccacccccccaaccccg
ctgctgctccgaaagctggcacagctggccacggaagaggccgagaggcagaggctagag
accctgtgccagccctcagaatacaacaagtggaagttcatcaacagccccacattcctg
gaggtgctggaggagttcccgtccctgcgggtgtctgctggcttcctgctctcccagctc
cctattctgaaaccccggtactactccatcagctcctccagggatcgcacacccacggag
gtgcacctcaccgtggccgtgctcacgtaccgcacccgagatggccaaggtcccttgcac
cacggtgtctgtagcacgtggctcagtagcctgaagccccaagacccagtaccctgcttc
gtgagaagtgccagcaacttccagctccctgaggacccctcccatccttgcatcctcatc
ggacctggcacaggcatcgcccccttccgcggtttctggcagcagcggctccatgacacc
aagtacaaagggctccaggccggccgcatgaccctggtgttcgggtgccgccgcccagat
gaggaccacctgtatcgggaggagatgctggagatggcccagaatggggtactgcatgag
gtgcacacagcctactctcgcctgccttgccagcccaaggtctatgttcaagacatcctg
cggcagcggctggccagcgaggtgctccgcgtgctgcacgaggagcacggccacctttat
gtctgtggggatgtgcgtatggcccgggatgtggcccataccctgaagctcctggtggct
gccaagctgaggctgagtgaggagcaggtggaggactactttttccagcttaagagccag
aagcgctatcatgaagatatctttggtgctgtgtttccctacgaggtgaaaaaagatggg
gcagcgaagcagcccagcgatcccaaagttacaacagcctacgggagaagttaa
DBGET
integrated database retrieval system
