KEGG   Ursus americanus (American black bear): 123777460
Entry
123777460         CDS       T07931                                 
Symbol
PPP3CC
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
uar  Ursus americanus (American black bear)
Pathway
uar04010  MAPK signaling pathway
uar04020  Calcium signaling pathway
uar04022  cGMP-PKG signaling pathway
uar04114  Oocyte meiosis
uar04218  Cellular senescence
uar04310  Wnt signaling pathway
uar04360  Axon guidance
uar04370  VEGF signaling pathway
uar04380  Osteoclast differentiation
uar04625  C-type lectin receptor signaling pathway
uar04650  Natural killer cell mediated cytotoxicity
uar04658  Th1 and Th2 cell differentiation
uar04659  Th17 cell differentiation
uar04660  T cell receptor signaling pathway
uar04662  B cell receptor signaling pathway
uar04720  Long-term potentiation
uar04724  Glutamatergic synapse
uar04728  Dopaminergic synapse
uar04921  Oxytocin signaling pathway
uar04922  Glucagon signaling pathway
uar04924  Renin secretion
uar05010  Alzheimer disease
uar05014  Amyotrophic lateral sclerosis
uar05020  Prion disease
uar05022  Pathways of neurodegeneration - multiple diseases
uar05031  Amphetamine addiction
uar05152  Tuberculosis
uar05163  Human cytomegalovirus infection
uar05166  Human T-cell leukemia virus 1 infection
uar05167  Kaposi sarcoma-associated herpesvirus infection
uar05170  Human immunodeficiency virus 1 infection
uar05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
uar05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:uar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123777460 (PPP3CC)
   04310 Wnt signaling pathway
    123777460 (PPP3CC)
   04370 VEGF signaling pathway
    123777460 (PPP3CC)
   04020 Calcium signaling pathway
    123777460 (PPP3CC)
   04022 cGMP-PKG signaling pathway
    123777460 (PPP3CC)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    123777460 (PPP3CC)
   04218 Cellular senescence
    123777460 (PPP3CC)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    123777460 (PPP3CC)
   04650 Natural killer cell mediated cytotoxicity
    123777460 (PPP3CC)
   04660 T cell receptor signaling pathway
    123777460 (PPP3CC)
   04658 Th1 and Th2 cell differentiation
    123777460 (PPP3CC)
   04659 Th17 cell differentiation
    123777460 (PPP3CC)
   04662 B cell receptor signaling pathway
    123777460 (PPP3CC)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    123777460 (PPP3CC)
   04921 Oxytocin signaling pathway
    123777460 (PPP3CC)
   04924 Renin secretion
    123777460 (PPP3CC)
  09156 Nervous system
   04724 Glutamatergic synapse
    123777460 (PPP3CC)
   04728 Dopaminergic synapse
    123777460 (PPP3CC)
   04720 Long-term potentiation
    123777460 (PPP3CC)
  09158 Development and regeneration
   04360 Axon guidance
    123777460 (PPP3CC)
   04380 Osteoclast differentiation
    123777460 (PPP3CC)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    123777460 (PPP3CC)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    123777460 (PPP3CC)
   05170 Human immunodeficiency virus 1 infection
    123777460 (PPP3CC)
   05163 Human cytomegalovirus infection
    123777460 (PPP3CC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123777460 (PPP3CC)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    123777460 (PPP3CC)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    123777460 (PPP3CC)
   05014 Amyotrophic lateral sclerosis
    123777460 (PPP3CC)
   05020 Prion disease
    123777460 (PPP3CC)
   05022 Pathways of neurodegeneration - multiple diseases
    123777460 (PPP3CC)
  09165 Substance dependence
   05031 Amphetamine addiction
    123777460 (PPP3CC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123777460 (PPP3CC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:uar01009]
    123777460 (PPP3CC)
Enzymes [BR:uar01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     123777460 (PPP3CC)
Protein phosphatases and associated proteins [BR:uar01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     123777460 (PPP3CC)
SSDB
Motif
Pfam: Metallophos DUF5378 DUF7084
Other DBs
NCBI-GeneID: 123777460
NCBI-ProteinID: XP_045630093
LinkDB
Position
Unknown
AA seq 534 aa
MSGRNLHLSTTERVIKAVPFPPTQRLTLKEVFENGKPKIDVLKNHLVKEGRLEEEVALKI
INDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGY
FSIECVLFLWSLKINHPKTVFLLRGNHECRHLTEYFTFKQECRIKYSEQVYDACMETFDC
LPLAALLNQQFLCVHGGMSPEITSLDDIKKLDRFKEPPAFGPVCDLLWSDPSEDYGNEKT
LEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLIT
IFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEM
LVNILNICSDDELISDDEIEDHYISSYRKGGTTVRKEIIKNKIRAIGKMARVFSILREES
ESVLTLKGLTPTGTLPLGVLSGGKQTIETATVEAVEAREAIRGFSLQHRIRSFEEARGLD
RINERMPPRKDSQYPDGPVKLVAPPQPNAAHRNDRGRRASNDAEPCCGTGGSKT
NT seq 1605 nt   +upstreamnt  +downstreamnt
atgtccgggaggaacctccacctctccaccaccgaacgcgtcatcaaagctgttcccttt
cctccaacccaacggcttactttgaaggaagtgtttgagaatgggaaacctaaaattgat
gttttgaaaaaccatttggtgaaagaagggcgactggaagaggaagtagccttaaagata
atcaatgatggggctgccatcctgagacaagagaagaccatgatagaagtagatgctcca
atcacggtgtgtggtgacattcatggacagttttttgacctgatgaagttgtttgaagtt
ggaggatcacctagtaacacacgctacctctttctgggtgactatgtggacagaggctat
ttcagtatagagtgtgtgctgtttttatggagtttaaagattaatcatcccaaaacagtg
tttctgcttcgaggaaatcatgaatgcaggcatcttacagaatacttcaccttcaaacag
gaatgtcgaatcaaatattctgaacaggtgtatgatgcgtgtatggagacatttgactgt
cttcctcttgctgccctcttaaaccagcagtttctgtgtgtacatggagggatgtcacct
gaaattactagtttagatgacattaagaaattagaccggtttaaagaacctccagccttt
gggccagtgtgtgacctgctttggtctgatccttcagaggattatggcaatgaaaagacc
ttggagcactatacccacaacactgtccgagggtgctcttatttttacagttaccctgca
gtctgtgaatttttgcagaacaataatttgttatcaataatcagagctcatgaagcccag
gatgctgggtatcgaatgtacaggaagagccaaacaacaggctttccgtcactcattaca
attttctctgcccccaattacctagatgtctataataataaagctgctgtgctaaaatac
gaaaacaatgtcatgaatatcaggcagtttaactgttctccacacccctactggcttccg
aactttatggacgttttcacatggtctttgccatttgttggggaaaaagtcacagagatg
ctggttaacattctcaacatatgctctgatgatgaattgatttccgatgatgaaattgaa
gatcactacatttcaagctatcggaaaggaggcactacagttcgaaaggaaatcatcaag
aataagatcagagccattgggaagatggcacgagtcttttcaattctgcgggaagagagt
gagagtgtgctgactctcaagggcctgactccaacagggacactccctctaggtgtcctc
tcaggaggaaaacagaccattgagacagccacagtagaagcggtagaggcccgggaagcc
atcagaggattttcgcttcagcacaggatccggagttttgaagaagcccgaggtctggac
cgaattaacgaacggatgccaccccgaaaagacagccagtaccctgatgggccagtgaaa
ttggttgcccctccacaacccaacgctgcgcacaggaacgacagggggagaagagccagt
aatgacgcagagccctgctgtggcacaggtggatccaaaacttaa

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