Ursus americanus (American black bear): 123777573
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Entry
123777573 CDS
T07931
Symbol
KEAP1
Name
(RefSeq) kelch-like ECH-associated protein 1
KO
K10456
kelch-like protein 19
Organism
uar
Ursus americanus (American black bear)
Pathway
uar04120
Ubiquitin mediated proteolysis
uar05012
Parkinson disease
uar05200
Pathways in cancer
uar05208
Chemical carcinogenesis - reactive oxygen species
uar05225
Hepatocellular carcinoma
uar05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
123777573 (KEAP1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123777573 (KEAP1)
05208 Chemical carcinogenesis - reactive oxygen species
123777573 (KEAP1)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
123777573 (KEAP1)
09164 Neurodegenerative disease
05012 Parkinson disease
123777573 (KEAP1)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
123777573 (KEAP1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
uar04121
]
123777573 (KEAP1)
Ubiquitin system [BR:
uar04121
]
Ubiquitin ligases (E3)
Multi subunit type E3
Cul3 complex
Adoptor and target recognizing subunit (BTB)
123777573 (KEAP1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Kelch_1
Kelch_6
Kelch_3
Kelch_2
BACK
Kelch_KLHDC2_KLHL20_DRC7
BTB
Kelch_4
Beta-prop_ATRN-LZTR1
BTB_KLHL33
NANM
Motif
Other DBs
NCBI-GeneID:
123777573
NCBI-ProteinID:
XP_045630279
LinkDB
All DBs
Position
Unknown
AA seq
624 aa
AA seq
DB search
MQPEPRPSGAGARTRFLPLRSQRPKGAGDTVMYASTECKAEVTPSQHGNRTFSYTLEDHT
KQAFGIMNELRLSQQLCDVTLQVKYEDAPAAQFMAHKVVLASSSPVFKAMFTNGLREQGM
EVVSIEGIHPKVMERLIEFAYTASISMGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLD
PSNAIGIANFAEQIGCAELHQRAREYIYMHFGEVAKQEEFFNLSHCQLVTLISRDDLNVR
CESEVFHACINWVKYDCEQRRFYVQALLRAVRCHSLTPHFLQMQLQKCEILQSDSRCKDY
LVKIFQELTLHKPTQVMPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQV
PRSGLAGCVVGGLLYAVGGRNNSPDGNTDSNALDCYNPMTNQWSPCAPMSVPRNRIGVGV
IDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDG
TNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVE
TETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTHMTSG
RSGVGVAVTMEPCRKQIDQQNCTC
NT seq
1875 nt
NT seq
+upstream
nt +downstream
nt
atgcagccggaacccaggcctagcggggctggggcccgcacccgattccttcccctgagg
tcacagcgccccaagggggcaggggacacggtgatgtacgcctccaccgagtgcaaagcc
gaggtgacaccctcccagcacggcaaccgcaccttcagctacacgctggaggaccacacc
aagcaggcctttggcatcatgaacgagctgcggctcagccagcagctgtgtgatgtgaca
ctgcaggtcaaatacgaggacgcgccagccgcccagttcatggctcacaaggtggtgctg
gcctcatctagccccgtcttcaaggccatgttcaccaacgggctacgggagcagggcatg
gaggtggtgtccattgagggcatccaccccaaggtcatggagcgcctaattgagtttgcc
tacacggcctccatctccatgggtgagaagtgtgtgctccacgtgatgaatggcgccgtc
atgtaccagatcgacagcgtcgtccgcgcctgcagcgacttcctcgtgcagcagctggac
cccagcaacgccattggcattgccaacttcgccgaacagatcggctgcgccgagctgcac
cagcgcgcccgcgaatatatctatatgcacttcggagaggtggccaagcaagaggagttc
ttcaacctgtcccattgccagctggtgacgctcatcagccgagacgatctgaacgtgcgc
tgcgagtccgaggtcttccacgcctgcatcaactgggtcaagtatgactgtgagcagcgg
cgtttctacgtgcaggcgctgctccgggctgtgcgatgccactcgctcacaccccacttc
ctgcagatgcagctccagaagtgtgagatcttgcagtcggactcccgctgcaaggactac
ctggtcaagatcttccaggagcttaccttgcacaagcccacacaggtgatgccctgtcgg
gcgcccaaagtgggccggctcatctacaccgctggtggctacttccgccagtcactcagc
tacctggaggcctacaaccccagtgatggcacctggctccgactggcagacctgcaggtg
ccccgtagtggcctggcaggctgcgtcgtgggtgggctgctgtatgctgtgggcggccga
aacaactcgcccgacggcaacaccgactccaatgccctggactgctataaccccatgacc
aaccagtggtcgccctgtgcccccatgagtgtaccacgcaatcggatcggggttggggtc
attgatgggcacatctatgctgttggtggctcccatggctgcatccaccacaacagtgtg
gagaggtatgagccagaacgggacgagtggcacttggtggccccaatgctgactcgaagg
atcggggtgggagtggctgtcctcaaccgtttgctctatgccgttgggggctttgatgga
acaaaccgcctcaactcagccgagtgttactacccagagagaaatgagtggcgaatgatc
acacccatgaacaccatccgaagtggggcaggagtctgtgtcttgcacaactgtatctat
gctgcggggggctacgacggtcaggaccagctgaacagcgtggagcgctatgacgtggag
acagaaacgtggacttttgtagctcccatgaagcatcggcgaagtgccctggggattact
gtgcaccagggaaggatctacgttctcggaggctacgatggtcacacgttcctggacagt
gtggagtgttacgatccagacacagacacctggagtgaggtgacccacatgacatctggc
cgcagtggggtgggtgttgctgtcaccatggaaccctgccggaagcagatcgaccagcag
aactgtacctgttga
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