KEGG   Ursus americanus (American black bear): 123778395
Entry
123778395         CDS       T07931                                 
Symbol
NDUFS8
Name
(RefSeq) NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial isoform X1
  KO
K03941  NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
Organism
uar  Ursus americanus (American black bear)
Pathway
uar00190  Oxidative phosphorylation
uar01100  Metabolic pathways
uar04714  Thermogenesis
uar04723  Retrograde endocannabinoid signaling
uar04932  Non-alcoholic fatty liver disease
uar05010  Alzheimer disease
uar05012  Parkinson disease
uar05014  Amyotrophic lateral sclerosis
uar05016  Huntington disease
uar05020  Prion disease
uar05022  Pathways of neurodegeneration - multiple diseases
uar05208  Chemical carcinogenesis - reactive oxygen species
uar05415  Diabetic cardiomyopathy
Module
uar_M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:uar00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    123778395 (NDUFS8)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    123778395 (NDUFS8)
  09159 Environmental adaptation
   04714 Thermogenesis
    123778395 (NDUFS8)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    123778395 (NDUFS8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    123778395 (NDUFS8)
   05012 Parkinson disease
    123778395 (NDUFS8)
   05014 Amyotrophic lateral sclerosis
    123778395 (NDUFS8)
   05016 Huntington disease
    123778395 (NDUFS8)
   05020 Prion disease
    123778395 (NDUFS8)
   05022 Pathways of neurodegeneration - multiple diseases
    123778395 (NDUFS8)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    123778395 (NDUFS8)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    123778395 (NDUFS8)
Enzymes [BR:uar01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     123778395 (NDUFS8)
SSDB
Motif
Pfam: Fer4 Fer4_7 Fer4_16 Fer4_21 Fer4_6 Fer4_9 Fer4_8 Fer4_2 Fer4_10 Fer4_4 LdpA_Fe-S-bd Fer4_17 Fer4_3
Other DBs
NCBI-GeneID: 123778395
NCBI-ProteinID: XP_045631653
UniProt: A0A452RZ77
LinkDB
Position
Unknown
AA seq 210 aa
MRCLTTSTLLRALAQAARAGHPTGRSLHSSTVAATYKFVNMREPTMDMKSVTDRAAQTLL
WTELIRGLGMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAV
CPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEE
LLYNKEKLLSNGDKWEAEIAANIQADYLYR
NT seq 633 nt   +upstreamnt  +downstreamnt
atgcgctgcctgactacgtctacactgcttcgggccctggcccaggctgcacgtgcaggg
catcccaccggccggagcctccacagcagcacagttgcagcgacctacaagttcgtgaac
atgcgggaacctacgatggacatgaagtcggtgaccgaccgggctgctcagaccctgctg
tggactgagctcatccgaggcctgggcatgaccctaagctacctgttccgggagcctgcc
accatcaactacccattcgagaagggcccactgagccctcgctttcggggagaacatgcg
ctgcgtcgctatccatcaggagaggagcgctgcattgcctgtaagctttgtgaggccgtc
tgccctgctcaggccatcaccatcgaggccgagccgcgggccgatggcagccgccggacc
acccgctatgacatcgacatgaccaagtgcatctactgcggcttctgccaggaggcctgc
cccgtggacgccattgtcgagggccccaacttcgagttctccaccgagacgcacgaggag
ctcctgtacaacaaggagaagctgctcagcaacggggacaagtgggaggcggagatcgcc
gccaacatccaggccgactacctgtaccgctga

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