Ursus americanus (American black bear): 123778404
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Entry
123778404 CDS
T07931
Symbol
RPS6KB2
Name
(RefSeq) ribosomal protein S6 kinase beta-2 isoform X1
KO
K04688
ribosomal protein S6 kinase beta [EC:
2.7.11.1
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar01521
EGFR tyrosine kinase inhibitor resistance
uar01522
Endocrine resistance
uar04012
ErbB signaling pathway
uar04066
HIF-1 signaling pathway
uar04140
Autophagy - animal
uar04150
mTOR signaling pathway
uar04151
PI3K-Akt signaling pathway
uar04152
AMPK signaling pathway
uar04211
Longevity regulating pathway
uar04213
Longevity regulating pathway - multiple species
uar04350
TGF-beta signaling pathway
uar04371
Apelin signaling pathway
uar04666
Fc gamma R-mediated phagocytosis
uar04714
Thermogenesis
uar04910
Insulin signaling pathway
uar04931
Insulin resistance
uar05163
Human cytomegalovirus infection
uar05165
Human papillomavirus infection
uar05170
Human immunodeficiency virus 1 infection
uar05200
Pathways in cancer
uar05205
Proteoglycans in cancer
uar05207
Chemical carcinogenesis - receptor activation
uar05210
Colorectal cancer
uar05212
Pancreatic cancer
uar05221
Acute myeloid leukemia
uar05224
Breast cancer
uar05225
Hepatocellular carcinoma
uar05226
Gastric cancer
uar05231
Choline metabolism in cancer
uar05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
123778404 (RPS6KB2)
04350 TGF-beta signaling pathway
123778404 (RPS6KB2)
04371 Apelin signaling pathway
123778404 (RPS6KB2)
04066 HIF-1 signaling pathway
123778404 (RPS6KB2)
04151 PI3K-Akt signaling pathway
123778404 (RPS6KB2)
04152 AMPK signaling pathway
123778404 (RPS6KB2)
04150 mTOR signaling pathway
123778404 (RPS6KB2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
123778404 (RPS6KB2)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
123778404 (RPS6KB2)
09152 Endocrine system
04910 Insulin signaling pathway
123778404 (RPS6KB2)
09149 Aging
04211 Longevity regulating pathway
123778404 (RPS6KB2)
04213 Longevity regulating pathway - multiple species
123778404 (RPS6KB2)
09159 Environmental adaptation
04714 Thermogenesis
123778404 (RPS6KB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123778404 (RPS6KB2)
05205 Proteoglycans in cancer
123778404 (RPS6KB2)
05207 Chemical carcinogenesis - receptor activation
123778404 (RPS6KB2)
05231 Choline metabolism in cancer
123778404 (RPS6KB2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
123778404 (RPS6KB2)
09162 Cancer: specific types
05210 Colorectal cancer
123778404 (RPS6KB2)
05212 Pancreatic cancer
123778404 (RPS6KB2)
05225 Hepatocellular carcinoma
123778404 (RPS6KB2)
05226 Gastric cancer
123778404 (RPS6KB2)
05221 Acute myeloid leukemia
123778404 (RPS6KB2)
05224 Breast cancer
123778404 (RPS6KB2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
123778404 (RPS6KB2)
05163 Human cytomegalovirus infection
123778404 (RPS6KB2)
05165 Human papillomavirus infection
123778404 (RPS6KB2)
09167 Endocrine and metabolic disease
04931 Insulin resistance
123778404 (RPS6KB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123778404 (RPS6KB2)
01522 Endocrine resistance
123778404 (RPS6KB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uar01001
]
123778404 (RPS6KB2)
Enzymes [BR:
uar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
123778404 (RPS6KB2)
Protein kinases [BR:
uar01001
]
Serine/threonine kinases: AGC group
RSK family [OT]
123778404 (RPS6KB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_C
Kinase-like
Pkinase_fungal
ABC1
Motif
Other DBs
NCBI-GeneID:
123778404
NCBI-ProteinID:
XP_045631683
UniProt:
A0A452QMR1
LinkDB
All DBs
Position
Unknown
AA seq
482 aa
AA seq
DB search
MAAVFDLDLETEEGSEGEPELSPSDVCPLAESRAAGLECVGHCEEMELTETSVNQGPERI
GPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNI
LESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLAL
GHLHSQGIIYRDLKPENIMLSGQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILV
RSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLILPPYLTPDARDLVKK
FLKRNPSQRIGGGPGDAADVQRHPFFRHINWDDLLARRVDPPFRPSLQSEEDVSQFDTHF
TRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRTPV
SPLKFSPFEGFRPSSGPLEPTEPPLPPLLPPPPPPPSSTAPLPIRPPSGTKKSKRGRGRP
GR
NT seq
1449 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggtgtttgacctggacctggagacggaggaaggcagcgagggcgagccagag
ttgagcccctcggacgtgtgtccccttgccgagtcgagggcggctggcctggagtgtgtg
ggacactgtgaggagatggagctcactgagaccagtgtgaaccagggccccgagcgcatc
gggccccactgctttgagctgctgcgtgtgctgggcaaggggggctatggcaaggtgttc
caagtgcgaaaggtgcagggcaccaacttgggcaaaatatatgccatgaaagtcctgagg
aaggccaaaattgtgcgcaacgccaaggacacagcacacacgcgggctgaacggaacatt
ctagagtcagtgaagcaccccttcattgtggaactggcctatgccttccagactggtggc
aaactctacctcatcctcgagtgcctcagtggcggtgagctcttcacgcatctggagcga
gagggcatcttcctggaagacacagcctgtttctacctggcggagatcacgctggccctg
ggccatctccactcccaaggcatcatctaccgggacctcaaacctgagaacatcatgctc
agcggccagggccacatcaaactgacagactttggtctgtgcaaggagtcgatccacgag
ggtgccgtcacccacactttctgtggcaccattgagtacatggcccctgagattctggta
cgcagcggccacaaccgggcagtggactggtggagcctgggggccctgatgtatgacatg
ctcactggatcgccacccttcactgcggagaaccggaagaaaaccatggacaagatcatc
aaagggaagctgattctgcccccctacctcacccctgatgcccgggaccttgtcaaaaag
tttctgaagcggaatcccagccaacggatcgggggtggccccggggatgctgctgatgtg
cagaggcaccccttcttccggcatattaattgggatgacctcctggctcgccgcgtagac
ccccctttcaggccctctctgcagtcagaggaggatgtgagccagtttgacacccacttc
acgcggcagacgccggtggacagtccagatgatacggccctcagtgagagcgcaaaccag
gccttcctgggcttcacatacgtggcaccctccgtcctggacagcatcaaggagggcttc
tccttccagcccaagctgcgctcccccaggcgcctcaacagcagcccccggaccccggtc
agccccctgaagttctcgccctttgagggattccggcccagctctggcccactggagccc
acggagccccctctacctcctctcctgccgccgccaccgccaccaccgtcgagcactgcc
ccactccccatccgacccccctcagggaccaagaagtctaagaggggccgtgggcgccca
ggccgctag
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