Ursus americanus (American black bear): 123778556 Help Entry 123778556         CDS       T07931                                  Symbol NOS1 Name (RefSeq) nitric oxide synthase, brain   KO K13240   nitric-oxide synthase, brain [EC:1.14.13.39] Organism uar  Ursus americanus (American black bear) Pathway uar00220   Arginine biosynthesis uar00330   Arginine and proline metabolism uar01100   Metabolic pathways uar04020   Calcium signaling pathway uar04081   Hormone signaling uar04145   Phagosome uar04371   Apelin signaling pathway uar04713   Circadian entrainment uar04730   Long-term depression uar04926   Relaxin signaling pathway uar04970   Salivary secretion uar05010   Alzheimer disease uar05014   Amyotrophic lateral sclerosis uar05022   Pathways of neurodegeneration - multiple diseases uar05410   Hypertrophic cardiomyopathy uar05412   Arrhythmogenic right ventricular cardiomyopathy uar05414   Dilated cardiomyopathy uar05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:uar00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     123778556 (NOS1)    00330 Arginine and proline metabolism     123778556 (NOS1)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     123778556 (NOS1)    04020 Calcium signaling pathway     123778556 (NOS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     123778556 (NOS1)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     123778556 (NOS1)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     123778556 (NOS1)   09154 Digestive system    04970 Salivary secretion     123778556 (NOS1)   09156 Nervous system    04730 Long-term depression     123778556 (NOS1)   09159 Environmental adaptation    04713 Circadian entrainment     123778556 (NOS1)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     123778556 (NOS1)    05014 Amyotrophic lateral sclerosis     123778556 (NOS1)    05022 Pathways of neurodegeneration - multiple diseases     123778556 (NOS1)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     123778556 (NOS1)    05412 Arrhythmogenic right ventricular cardiomyopathy     123778556 (NOS1)    05414 Dilated cardiomyopathy     123778556 (NOS1)    05416 Viral myocarditis     123778556 (NOS1) Enzymes [BR:uar01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      123778556 (NOS1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 Motif Other DBs NCBI-GeneID:  123778556 NCBI-ProteinID:  XP_045631946 LinkDB All DBs Position Unknown AA seq 1132 aa AA seqDB search MGSIMLPSQQIRRPEDVRTKEQLFPLAKEFIDQYYSSIKRFGSKAHTERLEEVNKEIEAT GTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHIKYATN KGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSILGDPANVEFTEICVQQGWK PPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNML LEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALV EINIAVLYSFQTDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVF HQEMLNYRLTPSFEYQPEPWNTHVWKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAK RVKATILYATETGKSQAYAKTLCEIFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGN GDPPENGEKFGCALMEMRHPNSVHEERKYPEPLRFFPRKGPPLPQGDPGVRGLAAARDSQ QRSYKVRFNSVSSYSDSHKSSGDGPDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGH AVDTLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSL ISNDRSWKRNKFRLTYMAEAPELTQGLSTVHKKRVSAARLLSRQNLQSPKSSRSTIFVRL HTNGNQELQYQPGDHLGVFPGNREDLVNALIERLEDAPPVNQLVKVELLEERNTALGVIS NWTDEHRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSEKEKQRLLVLSRGLQEYEE WKWGKNPTIVEVLEEFPSIQMPSTLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSY RTRDGEGPIHHGVCSSWLNRIQADEVVPCFVRGAPSFHLPRNPQVPCILIGPGTGIAPFR SFWQQRQFDIQHKGMSPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPD KPKKYVQDVLQEQLAEPVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDA GVFISRLRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS NT seq 3399 nt NT seq  +upstreamnt  +downstreamnt atgggctccatcatgctcccttctcagcaaatacgaaggcctgaagatgtccgcacaaaa gaacagctcttccctcttgccaaagagttcattgatcagtactactcgtcaattaaaaga tttggctccaaagcccacacagagaggctggaagaagtcaacaaagagatcgaggccaca ggcacctaccagctcaaagacacagagctcatctacggggcgaagcacgcctggcggaat gcctcccgctgcgttggcaggatccagtggtccaagctgcaggtgttcgatgcccgagac tgcaccacggctcacgggatgttcaactacatctgcaaccacatcaagtacgccaccaac aaagggaacctcaggtctgccatcaccatatttccgcagaggactgacggcaagcacgat ttccgagtctggaactctcagctcatccgctacgccggctacaagcagcctgacggctcc atcctaggggacccagccaatgtggaattcacagagatctgcgtacagcagggctggaaa cccccaaggggccgcttcgatgtcctgccactcctgctccaggccaacggcaacgacccc gagctcttccagattcctccagagctggtgttggaagtgcccatcagacaccccaagttt gagtggttcaaggatctgggcctgaagtggtacggcctccccgctgtgtctaatatgctg ctggagatcggcggcctggagttcagcgcctgccccttcagtggctggtacatgggcaca gagatcggcgttcgcgactactgtgacaactctcgatacaacatcctggaggaagtggcc aagaagatgaacttggatatgaggaagacatcctccctgtggaaggatcaggcgctggtg gaaatcaacattgctgttctctacagcttccagactgacaaagtgaccatcgttgaccac cactctgccaccgagtccttcattaagcacatggagaatgaataccgctgccgggggggc tgccccgccgactgggtgtggatcgtgccccccatgtctggcagcatcaccccggtcttc caccaggagatgctcaactaccggctcaccccctccttcgaataccagcctgagccttgg aacacccacgtgtggaaaggtaccaatgggacccccacaaagcggcgagccatcggcttc aagaagctggcggaagccgtcaagttttccgccaagctcatggggcaggcaatggccaag agggtcaaggcaaccatcctttatgccacagagacgggcaagtcgcaggcctatgctaaa accttgtgcgagatcttcaaacacgcctttgatgccaaggtgatgtccatggaagaatat gacattgtacacctggaacatgaaactctggtcctggtggttaccagcacttttggcaat ggagacccccctgagaatggggagaaattcggctgtgctttgatggaaatgaggcacccc aactccgtgcatgaggaaaggaagtacccggaacccttgcgtttctttccccgtaaaggg cctcccctcccccaaggtgacccaggagtccgtggtctggctgcagcccgtgacagccag cagaggagctacaaggtccgattcaatagcgtttcctcgtattctgactcccataaatcg tcgggcgatgggccagacctcagagacaactttgagagtgctggacccctggcaaatgtg aggttctctgtgtttggccttggctcccgtgcttacccgcacttctgtgcctttggacat gctgtggacaccctcctggaggagctgggaggagagaggatcctaaagatgagggaaggg gatgagctgtgtgggcaggaagaggctttcaggacctgggccaagaaggtcttcaaggca gcctgtgatgtgttctgtgtgggagatgacgtcaacatcgagaaggccaacaactccctc atcagcaatgaccgcagctggaagaggaacaaattccgcctcacctacatggccgaagct ccagaacttacgcaaggtctgtccactgtccacaaaaagcgggtctcagccgctcgactc ctcagccgtcagaaccttcagagccctaaatccagccgatcaaccatcttcgtgcgtctc cacaccaacgggaatcaggagctccagtaccagcctggggaccacctgggcgtcttccca ggcaaccgcgaggacctcgtgaacgccctgatcgagcggctggaggacgcacccccggtc aaccagctggtgaaggtggagctgctggaggagcggaacacggctttgggagttatcagt aactggacagatgagcaccgcctcccgccctgcaccatcttccaggccttcaagtattac ctggacatcaccacgccgccaacgccactgcagctgcagcagtttgcctccctggccacc agcgagaaagagaagcagcgtctgctggtcctcagcaggggtttgcaggagtacgaggaa tggaaatggggcaagaaccccaccatcgtggaggtgctggaggagttcccgtccatccag atgccctccaccctgctcctgacccagctgtccctgctgcagccccgctactattccatc agctcctccccagacatgtaccctgacgaggtgcacctcaccgtggccatcgtctcctac cgcacccgagatggagaaggaccaattcaccacggtgtgtgctcctcctggctcaaccgg atacaggctgacgaagtggtcccgtgtttcgtgagaggagcacccagcttccacctgccc cgaaatccccaagtgccctgcatcctcattggcccaggcactggcattgcccctttccga agcttctggcagcagcggcaatttgatatccaacacaaagggatgagcccctgccccatg gtcctggtgttcgggtgccggcaatccaagatagaccacatctacagggaggagacgctc caggccaagaacaagggggtcttcagagaactgtacacggcctactcccgggagccagac aaaccaaagaagtacgtgcaggacgtcctgcaggagcagctggcagaaccggtgtaccga gccctgaaggagcaagggggccacatctatgtctgcggggacgtcaccatggccgccgac gtcctcaaagccatccagcgcatcatgacccagcaggggaaactctcagcagaggatgcg ggcgtgttcatcagcaggctgagggatgacaaccggtaccatgaggatattttcggggtc accctgcgaacatatgaagtgaccaaccgccttagatctgaatccattgccttcattgag gagagcaaaaaagacaccgacgaggttttcagctcctaa

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