| Entry |
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| Symbol |
ABCC1
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| Name |
(RefSeq) multidrug resistance-associated protein 1 isoform X1
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| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
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| Organism |
uar Ursus americanus (American black bear)
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| Pathway |
| uar04977 | Vitamin digestion and absorption |
| uar04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:uar00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
123778601 (ABCC1)
09132 Signal transduction
04071 Sphingolipid signaling pathway
123778601 (ABCC1)
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
123778601 (ABCC1)
04981 Folate transport and metabolism
123778601 (ABCC1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
123778601 (ABCC1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
123778601 (ABCC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:uar02000]
123778601 (ABCC1)
Enzymes [BR:uar01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
123778601 (ABCC1)
Transporters [BR:uar02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
123778601 (ABCC1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1570 aa
MALRGFCSADGSEPFWAWDVTWNTSNPDFTKCFQNTFLVWVPCSYLWVCFPFYFLYLSRH
DRGYIQMTYLNKTKTALGFLLWIVCWADLFYSFWERSWGKFLAPVFLVSPTLLGITMLLA
TFLIQLERRKGVQSSGIMLTFWLVALLCALAILRSKIMTALKEDAEIDVFRDVTFYIYFS
LVLMQLVLSCFSDRPPLFSETIHDPNPCPESSASFLSRVTFWWITGLMVRGYRQPLESTD
LWSLNKEDTSEQVVPVLVKNWKKECAKSKRQQAKMAYSSKDPAKPKGGSQVDVNEEAEVL
IVKSPQKEREPSLFKVLYKTFGPYFLMSFLFKALHDLMMFAGPEILKLLINFVNDQKAPD
WQGYFYTVLLFVSACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTV
GEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMILMVPLN
AVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLK
KSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDKNNILDAQKAFVSLALFNILRFPLNILP
MVISSIVQASVSLKRLRIFLSHEELEPDSIERRPIKDGGGANSISVKNATFTWARSEPPT
LSGITFSIPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVAVKGSVAYVPQQAWIQND
SLRENILFGRQLQERYYNAVIEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLAR
AVYCDSDIYLFDDPLSAVDAHVGKHIFENVIGPKGMLRNKTRLLVTHSISYLPQVDVILV
MTGGKISEMGSYQELLARDGAFAEFLRTYASGEQEQAEHDDGGQESYRFTHEPLYLEGLT
SVSSPGKEVKQMENGMLVTDVAGKQLKRQLSNSSSYSGDVGRHHTSTAELQKAGAKNEDA
WKLVEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFLCNNVAALASNYWLSLWTDDPI
VNGTQEHTKVRLSVYGALGISQGISVFGYSMAVSIGGIFASRRLHVDLLQNVLRSPMSFF
ERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGACIIILLATPIAAIIIPPLGL
IYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSIIRAFEEQERFIRQSDLKVDE
NQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYL
NWLVRMSSEMETNIVAVERLKEYSETEKEAPWRVEEMTPPSDWPQVGRVEFRDYGLRYRE
NLDLVLKNINITIDGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIVDNINIAKIGLH
DLRFKITIIPQDPVLFSGSLRMNLDPFSRYSDEEVWTSLELAHLKDFVSGLPDKLNHECA
EGGENLSSGLGSGFGMVLTLCLLVFLCWSSVGQRQLVCLARALLRKTKILVLDEATAAVD
LETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIRECGQPSALLQQRGLF
YSMAKDAGLV |
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| NT seq |
4713 nt +upstreamnt +downstreamnt
atggcgctccgcggcttctgcagcgctgatggctccgaacccttctgggcgtgggatgtc
acgtggaacaccagcaatcccgacttcaccaagtgctttcagaacacgttcctcgtatgg
gtgccttgttcttacctctgggtctgcttccccttctacttcctctatctctcacgccat
gaccggggctacattcagatgacctatctcaacaaaaccaaaactgccttgggatttttg
ctgtggatcgtctgctgggcagacctcttctactctttctgggaaagaagttggggcaaa
ttcctggccccggtgtttctggtcagcccaaccctcttgggcatcactatgctgcttgct
acctttttaattcaactcgagagaaggaagggagtccagtcctcggggatcatgctcact
ttctggcttgtagccctactgtgtgcccttgccatcttgagatccaaaatcatgactgcc
ttaaaagaggatgctgaaatcgacgtgtttcgcgatgtcactttctacatttacttttcc
ctcgtgctgatgcagctcgtgctgtcctgcttctcggaccgaccgcccctgttctctgaa
accatccacgaccccaatccctgcccggaatccagcgcctccttcctttccagagtcacc
ttctggtggatcacagggctgatggtccggggctaccgccagcccctggagagcactgac
ctctggtccctgaataaggaggacacgtcagaacaagttgtgcccgttttggtaaagaac
tggaagaaggagtgtgccaaatccaaaaggcagcaggcgaagatggcgtactcctccaag
gatcccgccaagcccaaagggggctcgcaggtggatgtgaatgaggaggctgaggttttg
attgtcaagtccccccagaaggagcgggagccatctctcttcaaggtgttatacaagacc
tttggaccctacttcctcatgagcttcttattcaaggccctccatgacctgatgatgttt
gctggcccagagatcttaaagttgctcatcaacttcgtgaacgatcagaaggccccggac
tggcagggctacttctacaccgtgctgctgttcgtcagcgcctgcctccagaccctcgtg
ctgcaccagtacttccacatctgcttcgttagcggcatgaggatcaagacggccgtcatc
ggggccgtctaccggaaggctttggtgatcaccaactcagccagaaaatcctccaccgtc
ggggagattgtcaacctcatgtctgtggacgcccagagattcatggacctggccacgtac
attaacatgatctggtcggctcctctgcaagtcatccttgctctctacctcctgtggctg
aacctgggcccgtccgtcctggctggggtggctgtgatgatcctcatggttcccctcaat
gccgtgatggccatgaagaccaagacctaccaggtggcccacatgaagagcaaagacaat
cggatcaagctgatgaatgagattctcaacgggatcaaagtactcaagctttatgcctgg
gagctggccttcaaagacaaggtgctggccatcaggcaggaggagctgaaggtgctcaag
aagtcggcctacctggcggctgtgggaaccttcacctgggtctgcacacctttcctggtg
gccctgtctacattcgccgtctacgtgaccgttgacaagaacaacatcctggacgcccag
aaagctttcgtgtccttggccttgtttaacatcctccgatttcccctgaatattctgccc
atggtcatcagcagcatcgtgcaggcgagtgtctccctcaaacgcctcaggatctttctg
tctcacgaggagctggagcctgacagcattgagcgaaggcccatcaaagacggcgggggc
gcaaacagcatctctgtgaagaatgccacgttcacgtgggccaggagcgaacctccgacg
ctaagtggcatcaccttctccattccggaaggttccttggtggccgtcgtgggccaggtg
ggctgtggaaagtcgtctctgctctcagcactcctggccgagatggacaaggtggagggg
cacgtggctgtcaagggctcagtggcctacgtcccccagcaggcctggattcagaatgat
tctctccgagaaaacatccttttcggccgccagctgcaggaacggtattataatgctgtc
attgaagcctgtgccctcctcccagatctagaaatcctgcccagtggggaccggacagag
attggtgagaagggtgtgaacctgtctgggggccagaagcagcgtgtgagcctggcccgg
gccgtgtactgtgactccgacatctacctcttcgacgaccccctgtcggccgtggatgcc
catgtgggaaaacacatatttgaaaacgtgattggccccaaggggatgctgaggaacaag
actcggctgctggtcacacacagcatcagctacctgccccaggtggatgtcatcctcgtc
atgaccggtggcaagatctccgagatgggctcctaccaggaactgctggcccgggacggc
gccttcgccgagttcctgcgcacatatgccagcggcgagcaggagcaggccgagcacgat
gatggtggccaagagagttacagattcactcatgagcctttgtacctggaagggttaaca
agtgtcagcagtccagggaaggaggtgaagcagatggagaatggcatgctggtgacggat
gtcgcggggaagcagctgaagagacagctcagcaactcctcctcctacagcggagacgtt
ggccgccaccacaccagcacggctgagctgcagaaagcgggggccaagaatgaggacgcg
tggaagctggtggaggcagacaaggctcagacggggcaggtcaagctgtccgtgtactgg
gactacatgaaggcaatcggacttttcatctcctttctgagcatcttccttttcctgtgt
aacaacgttgcggctctggcctctaactactggctcagcctctggacagatgaccccatc
gtcaatgggacccaggagcacactaaagtccggctgagtgtctatggagccctgggcatt
tcgcaaggtatctcggtgttcggctactccatggcggtgtccattggggggatcttcgct
tcccgccgcctgcacgtggacctgctacagaacgtcctccggtcgcccatgagcttcttc
gagcggacccccagcgggaacctggtgaaccgcttctccaaggagctggacacggtggac
tccatgatcccgcaggtcatcaagatgttcatgggctccctgttcagcgtcatcggcgcc
tgcatcatcatcctgctggccacccccatcgctgccatcatcatcccgccgctgggcctc
atctacttcttcgtccagaggttctacgtggcctcgtcgcggcagctgaagcgcctcgag
tcggtgagccgctccccggtgtactcgcacttcaacgagaccctgctgggcgtcagcatc
atccgcgccttcgaggagcaggagcgcttcatccgccagagtgacctgaaggtggacgag
aaccagaaggcctattaccccagcatcgtggccaacaggtggctggctgtgcggctggag
tgtgtaggaaactgcatcgtcctgttcgctgccctattcgccgtgatctccaggcacagt
ctcagcgccggcttggtgggcctgtctgtgtcatactcactgcaggtgaccacgtacttg
aactggctggttcgcatgtcgtccgagatggagaccaacattgtggcggtggagaggctg
aaggagtattcagaaacggagaaagaggctccctggcgagtggaggagatgactccgccc
agtgactggcctcaggtgggccgagtggaattccgagactacggcctgcgttaccgagaa
aacctggacttggttctcaaaaacatcaacatcaccatagatggaggggaaaaggttggc
atcgtggggcggacgggagctgggaagtcgtccctgaccctgggcttgttccggatcaat
gagtctgctgagggggagatcattgttgacaacatcaacattgccaagattggcctacat
gatctgcgcttcaagatcaccatcatcccgcaggaccctgttttgttctcgggttccctc
cgcatgaacctggacccgttcagccggtactcagatgaggaagtctggacgtccctggag
ctggctcacctgaaggactttgtgtccggccttcccgacaagctgaaccacgagtgtgca
gaaggcggggagaacctgagctccggcctgggctcagggttcgggatggttttgaccctg
tgtctcctggtctttctgtgctggtcaagtgttgggcagcgccagcttgtgtgcctggcc
cgggctctgctgaggaagaccaagatccttgtgttggacgaggccacggcggccgtggac
ctcgagacggacgacctcattcagtctaccatccggacgcagtttgaagactgcaccgtg
ctcaccattgcacaccggctcaataccatcatggactacacaagggtcatcgtcctagac
aagggagagatccgggagtgcggccagccctccgccctcctgcagcagaggggtcttttc
tacagcatggccaaagacgctggcctggtgtga |
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