KEGG   Ursus americanus (American black bear): 123778823
Entry
123778823         CDS       T07931                                 
Symbol
PRKCB
Name
(RefSeq) protein kinase C beta type isoform X1
  KO
K19662  classical protein kinase C beta type [EC:2.7.11.13]
Organism
uar  Ursus americanus (American black bear)
Pathway
uar01521  EGFR tyrosine kinase inhibitor resistance
uar04010  MAPK signaling pathway
uar04012  ErbB signaling pathway
uar04014  Ras signaling pathway
uar04015  Rap1 signaling pathway
uar04020  Calcium signaling pathway
uar04062  Chemokine signaling pathway
uar04064  NF-kappa B signaling pathway
uar04066  HIF-1 signaling pathway
uar04070  Phosphatidylinositol signaling system
uar04071  Sphingolipid signaling pathway
uar04082  Neuroactive ligand signaling
uar04150  mTOR signaling pathway
uar04270  Vascular smooth muscle contraction
uar04310  Wnt signaling pathway
uar04370  VEGF signaling pathway
uar04510  Focal adhesion
uar04540  Gap junction
uar04613  Neutrophil extracellular trap formation
uar04650  Natural killer cell mediated cytotoxicity
uar04662  B cell receptor signaling pathway
uar04666  Fc gamma R-mediated phagocytosis
uar04670  Leukocyte transendothelial migration
uar04713  Circadian entrainment
uar04720  Long-term potentiation
uar04723  Retrograde endocannabinoid signaling
uar04724  Glutamatergic synapse
uar04725  Cholinergic synapse
uar04726  Serotonergic synapse
uar04727  GABAergic synapse
uar04728  Dopaminergic synapse
uar04730  Long-term depression
uar04750  Inflammatory mediator regulation of TRP channels
uar04911  Insulin secretion
uar04912  GnRH signaling pathway
uar04916  Melanogenesis
uar04918  Thyroid hormone synthesis
uar04919  Thyroid hormone signaling pathway
uar04921  Oxytocin signaling pathway
uar04925  Aldosterone synthesis and secretion
uar04928  Parathyroid hormone synthesis, secretion and action
uar04929  GnRH secretion
uar04931  Insulin resistance
uar04933  AGE-RAGE signaling pathway in diabetic complications
uar04935  Growth hormone synthesis, secretion and action
uar04960  Aldosterone-regulated sodium reabsorption
uar04961  Endocrine and other factor-regulated calcium reabsorption
uar04970  Salivary secretion
uar04971  Gastric acid secretion
uar04972  Pancreatic secretion
uar04973  Carbohydrate digestion and absorption
uar05017  Spinocerebellar ataxia
uar05022  Pathways of neurodegeneration - multiple diseases
uar05031  Amphetamine addiction
uar05032  Morphine addiction
uar05140  Leishmaniasis
uar05143  African trypanosomiasis
uar05146  Amoebiasis
uar05161  Hepatitis B
uar05163  Human cytomegalovirus infection
uar05164  Influenza A
uar05170  Human immunodeficiency virus 1 infection
uar05171  Coronavirus disease - COVID-19
uar05200  Pathways in cancer
uar05205  Proteoglycans in cancer
uar05206  MicroRNAs in cancer
uar05207  Chemical carcinogenesis - receptor activation
uar05214  Glioma
uar05223  Non-small cell lung cancer
uar05225  Hepatocellular carcinoma
uar05231  Choline metabolism in cancer
uar05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:uar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123778823 (PRKCB)
   04012 ErbB signaling pathway
    123778823 (PRKCB)
   04014 Ras signaling pathway
    123778823 (PRKCB)
   04015 Rap1 signaling pathway
    123778823 (PRKCB)
   04310 Wnt signaling pathway
    123778823 (PRKCB)
   04370 VEGF signaling pathway
    123778823 (PRKCB)
   04064 NF-kappa B signaling pathway
    123778823 (PRKCB)
   04066 HIF-1 signaling pathway
    123778823 (PRKCB)
   04020 Calcium signaling pathway
    123778823 (PRKCB)
   04070 Phosphatidylinositol signaling system
    123778823 (PRKCB)
   04071 Sphingolipid signaling pathway
    123778823 (PRKCB)
   04150 mTOR signaling pathway
    123778823 (PRKCB)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    123778823 (PRKCB)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    123778823 (PRKCB)
   04540 Gap junction
    123778823 (PRKCB)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    123778823 (PRKCB)
   04650 Natural killer cell mediated cytotoxicity
    123778823 (PRKCB)
   04662 B cell receptor signaling pathway
    123778823 (PRKCB)
   04666 Fc gamma R-mediated phagocytosis
    123778823 (PRKCB)
   04670 Leukocyte transendothelial migration
    123778823 (PRKCB)
   04062 Chemokine signaling pathway
    123778823 (PRKCB)
  09152 Endocrine system
   04911 Insulin secretion
    123778823 (PRKCB)
   04929 GnRH secretion
    123778823 (PRKCB)
   04912 GnRH signaling pathway
    123778823 (PRKCB)
   04921 Oxytocin signaling pathway
    123778823 (PRKCB)
   04935 Growth hormone synthesis, secretion and action
    123778823 (PRKCB)
   04918 Thyroid hormone synthesis
    123778823 (PRKCB)
   04919 Thyroid hormone signaling pathway
    123778823 (PRKCB)
   04928 Parathyroid hormone synthesis, secretion and action
    123778823 (PRKCB)
   04916 Melanogenesis
    123778823 (PRKCB)
   04925 Aldosterone synthesis and secretion
    123778823 (PRKCB)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    123778823 (PRKCB)
  09154 Digestive system
   04970 Salivary secretion
    123778823 (PRKCB)
   04971 Gastric acid secretion
    123778823 (PRKCB)
   04972 Pancreatic secretion
    123778823 (PRKCB)
   04973 Carbohydrate digestion and absorption
    123778823 (PRKCB)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    123778823 (PRKCB)
   04961 Endocrine and other factor-regulated calcium reabsorption
    123778823 (PRKCB)
  09156 Nervous system
   04724 Glutamatergic synapse
    123778823 (PRKCB)
   04727 GABAergic synapse
    123778823 (PRKCB)
   04725 Cholinergic synapse
    123778823 (PRKCB)
   04728 Dopaminergic synapse
    123778823 (PRKCB)
   04726 Serotonergic synapse
    123778823 (PRKCB)
   04720 Long-term potentiation
    123778823 (PRKCB)
   04730 Long-term depression
    123778823 (PRKCB)
   04723 Retrograde endocannabinoid signaling
    123778823 (PRKCB)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123778823 (PRKCB)
  09159 Environmental adaptation
   04713 Circadian entrainment
    123778823 (PRKCB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123778823 (PRKCB)
   05206 MicroRNAs in cancer
    123778823 (PRKCB)
   05205 Proteoglycans in cancer
    123778823 (PRKCB)
   05207 Chemical carcinogenesis - receptor activation
    123778823 (PRKCB)
   05231 Choline metabolism in cancer
    123778823 (PRKCB)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    123778823 (PRKCB)
   05214 Glioma
    123778823 (PRKCB)
   05223 Non-small cell lung cancer
    123778823 (PRKCB)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    123778823 (PRKCB)
   05161 Hepatitis B
    123778823 (PRKCB)
   05171 Coronavirus disease - COVID-19
    123778823 (PRKCB)
   05164 Influenza A
    123778823 (PRKCB)
   05163 Human cytomegalovirus infection
    123778823 (PRKCB)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    123778823 (PRKCB)
   05140 Leishmaniasis
    123778823 (PRKCB)
   05143 African trypanosomiasis
    123778823 (PRKCB)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    123778823 (PRKCB)
   05022 Pathways of neurodegeneration - multiple diseases
    123778823 (PRKCB)
  09165 Substance dependence
   05031 Amphetamine addiction
    123778823 (PRKCB)
   05032 Morphine addiction
    123778823 (PRKCB)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    123778823 (PRKCB)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    123778823 (PRKCB)
   04933 AGE-RAGE signaling pathway in diabetic complications
    123778823 (PRKCB)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    123778823 (PRKCB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:uar01001]
    123778823 (PRKCB)
Enzymes [BR:uar01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     123778823 (PRKCB)
Protein kinases [BR:uar01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   123778823 (PRKCB)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C Kinase-like ABC1 CEP76-C2
Other DBs
NCBI-GeneID: 123778823
NCBI-ProteinID: XP_045632407
LinkDB
Position
Unknown
AA seq 673 aa
MADPAAGPPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGS
LLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIEREVLIVVVRDA
KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRL
SVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFKLLSQEEGEYFNVPVPPEGSEGNEE
LRQKFERAKISQGTKAPEEKTTNTISKLDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSE
RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVM
EYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHI
KIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP
FEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFF
RYIDWEKLERKEIQPPYKPKACGRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFS
FVNSEFLKPEVKS
NT seq 2022 nt   +upstreamnt  +downstreamnt
atggctgacccggctgcggggccgccgccgagcgagggcgaggagagcaccgtgcgcttc
gcccgcaaaggcgccctccggcagaagaacgtgcacgaggtgaagaaccacaaattcacc
gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggggcttc
ggaaagcaaggattccagtgccaagtctgctgttttgttgtgcacaagcggtgccatgaa
tttgtcaccttctcctgcccaggcgccgacaaaggcccagcctccgatgacccccggagc
aaacacaagtttaagatccacacgtactccagccccacgttttgtgaccactgtgggtca
ctgctgtatggactcatccaccaggggatgaagtgtgacacctgcatgatgaacgtgcac
aaacgctgcgtgatgaacgtccccagcctgtgcggcacagaccacacggagcgccgcggc
cgcatctacatccaggcccacatcgagagggaagtcctcatcgtagtcgtaagagatgct
aaaaaccttgtacctatggaccccaatggcttgtcagacccttacgtgaaactgaaactg
attcctgaccccaagagcgagagcaagcagaagaccaaaaccatcaagtgctccctcaac
cctgagtggaatgagacattcagattccaactgaaagaatcggacaaagacagaagactg
tctgtagagatttgggattgggatctgaccagcaggaatgacttcatgggatctttgtcg
tttgggatttccgaactgcagaaagctggtgttgatggctggtttaagctgctgagccag
gaggaaggcgagtacttcaatgtgcctgtgccgccggaaggaagcgaaggcaatgaagag
ctacggcagaaattcgagagggccaagatcagtcaggggaccaaggctccagaagaaaag
acgaccaacaccatatccaaacttgacaacaacgggaacagagaccgaatgaaactgacc
gattttaacttcctgatggtgctcgggaaaggaagctttggcaaggtcatgctctctgag
cgaaaaggcacggacgagctctatgctgtgaagatcctgaagaaggacgtcgtgatccag
gatgacgatgtggagtgcacgatggtggagaagcgggtgctggccctgcctgggaagccg
ccgttcctgacccaactgcattcctgcttccagaccatggaccgcctgtactttgtgatg
gagtatgtgaacgggggcgacctcatgtaccacatccaacaagtcggccggtttaaggag
cctcacgctgtattttacgctgccgaaattgccatcggtctgttcttcttacagagcaag
ggcatcatttaccgtgacctcaaacttgacaatgtgatgctggattcagagggccacatc
aagattgctgattttggcatgtgcaaagaaaacatctgggatggggtgaccaccaagaca
ttctgtggcactccagactacatcgcccctgagatcattgcctaccagccctatgggaag
tctgtggattggtgggcctttggagtcctgctgtatgaaatgttggctgggcaggcaccc
tttgaaggggaggatgaggatgaactcttccagtccatcatggaacacaatgtggcttac
cccaagtccatgtccaaggaagctgtggccatctgcaaagggctgatgaccaaacacccg
ggcaaacgtctgggttgcggacccgaaggtgaacgtgacatcaaggagcatgcgtttttc
cggtatattgattgggagaaacttgaacgcaaagagattcagcccccgtataagccaaaa
gcctgtgggcgaaatgctgaaaacttcgaccggtttttcacccgccatccaccagtccta
acacctcccgaccaggaagtcatcaggaatattgaccagtcagaattcgaaggattttcc
tttgttaactctgaatttttaaaacctgaagtcaagagctaa

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