Ursus americanus (American black bear): 123779203
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Entry
123779203 CDS
T07931
Symbol
ATP2A2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar04020
Calcium signaling pathway
uar04022
cGMP-PKG signaling pathway
uar04024
cAMP signaling pathway
uar04148
Efferocytosis
uar04260
Cardiac muscle contraction
uar04261
Adrenergic signaling in cardiomyocytes
uar04380
Osteoclast differentiation
uar04919
Thyroid hormone signaling pathway
uar04972
Pancreatic secretion
uar05010
Alzheimer disease
uar05017
Spinocerebellar ataxia
uar05022
Pathways of neurodegeneration - multiple diseases
uar05410
Hypertrophic cardiomyopathy
uar05412
Arrhythmogenic right ventricular cardiomyopathy
uar05414
Dilated cardiomyopathy
uar05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
123779203 (ATP2A2)
04024 cAMP signaling pathway
123779203 (ATP2A2)
04022 cGMP-PKG signaling pathway
123779203 (ATP2A2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
123779203 (ATP2A2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
123779203 (ATP2A2)
09153 Circulatory system
04260 Cardiac muscle contraction
123779203 (ATP2A2)
04261 Adrenergic signaling in cardiomyocytes
123779203 (ATP2A2)
09154 Digestive system
04972 Pancreatic secretion
123779203 (ATP2A2)
09158 Development and regeneration
04380 Osteoclast differentiation
123779203 (ATP2A2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
123779203 (ATP2A2)
05017 Spinocerebellar ataxia
123779203 (ATP2A2)
05022 Pathways of neurodegeneration - multiple diseases
123779203 (ATP2A2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
123779203 (ATP2A2)
05412 Arrhythmogenic right ventricular cardiomyopathy
123779203 (ATP2A2)
05414 Dilated cardiomyopathy
123779203 (ATP2A2)
05415 Diabetic cardiomyopathy
123779203 (ATP2A2)
Enzymes [BR:
uar01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
123779203 (ATP2A2)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Cation_ATPase
Cation_ATPase_C
E1-E2_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
123779203
NCBI-ProteinID:
XP_045633089
LinkDB
All DBs
Position
Unknown
AA seq
997 aa
AA seq
DB search
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDRVEGDSCSLHEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGV
KQKVMSVIREWGSGSDTLRCLALATHDNPLRREEMNLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL
NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKDDNPDFEGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEPAILE
NT seq
2994 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcgcacacaaagacggtggaggaggtgctgggccacttcggcgtcaacgag
agcacggggctgagcctggagcaggtcaagaagctcaaggagagatggggctctaacgag
ttaccggctgaagaaggaaaaaccttgctggaacttgtgatcgagcagtttgaagactta
ctagttagaattttattgctggcagcttgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaacaattacagcctttgtagaaccctttgtaattttacttatattagtagcc
aatgcaattgtgggtgtatggcaggaaagaaatgctgagaatgcaatcgaagcccttaag
gaatatgagcctgaaatgggcaaagtatatcgacaggacagaaagagtgtccagcggatt
aaagctaaagacatagttcctggtgatattgtagaaattgctgttggtgacaaagttcct
gcagatataagattaacttccatcaaatctactactctaagggttgaccagtccattctc
acaggtgagtctgtgtctgtcatcaagcacactgaccctgtcccggacccacgggctgtc
aatcaagataaaaagaacatgctcttttctggtacaaacattgctgctggcaaagccatg
ggagtggtggtggcaactggagtgaacacagaaattggcaagatccgggatgaaatggtg
gcaacagagcaggagagaacccccctccagcagaaactagacgagtttggtgaacagctt
tcgaaagtcatctccctgatttgcattgcagtctggatcataaacattgggcacttcaat
gacccagttcatggaggctcctggatcaggggcgctatttactacttcaaaattgcagtg
gctctggctgtggcagccattcctgaaggtctgcctgctgtcatcaccacctgcctggct
cttggaactcgcagaatggcaaagaaaaatgctattgttcgaagcctcccttctgtggaa
acccttggttgtacttctgttatctgctcagacaagactggtacactgacaacaaaccag
atgtctgtgtgcaggatgttcattctggacagagttgaaggtgatagttgttcccttcat
gagtttaccattactggatcaacatacgcacctattggagaagtgcataaagatgataaa
ccagtgaaatgtcatcaatatgatggtcttgtggaattggcaacaatttgtgctctttgt
aatgattccgcattggattacaatgaggcgaagggtgtatatgaaaaagttggagaagct
acagagactgctctcacttgcctagtagagaagatgaatgtatttgataccgaattgaag
ggtctttctaaaatagagcgagcaaatgcctgcaactcggtcattaagcagttgatgaaa
aaggaattcactctggagttttcacgtgatagaaaatcgatgtcagtttattgtacacca
aacaaacctagccggacatcaatgagcaaaatgtttgtgaagggtgctcctgaaggtgtc
attgacaggtgcacccacattcgagttggaagtactaaagtgcctatgaccccgggagtc
aaacagaaggtcatgtctgtcattcgggaatggggtagcggcagcgacacactgcggtgt
ctggctctggccactcacgacaacccactgagaagagaagaaatgaaccttgaggactct
gccaactttattaaatatgagaccaatctgacctttgttggctgcgtgggcatgctggac
cctccaagaattgaagtggcctcttctgtgaagctgtgccggcaagcaggcatccgggtc
atcatgatcacaggggacaacaagggcactgctgtggccatctgtcggcgcattggaatc
ttcgggcaggacgaggatgtgacatcaaaggcttttacgggtcgggagtttgatgagctc
aatccttcagcccagagagatgcctgtttgaatgcccgctgttttgctcgagttgaacct
tcccacaagtcaaaaattgtagaatttcttcagtcttttgatgagattacagctatgact
ggggatggcgtgaatgacgctcctgccctgaagaaatcggagatcggcatcgccatgggg
tccggcacggcagtggctaaaaccgcctctgagatggtcctggccgatgacaacttctcc
accatcgtggccgctgtcgaggaggggcgggcaatctacaacaatatgaagcagttcatc
cgctacctcatctcatcaaatgtgggggaagttgtctgtatcttcctgacggcagctctt
ggatttcctgaggctttaattcctgtccagctcctctgggtcaatctggtgacagacggc
ctgcctgccaccgccctggggtttaaccctcctgatctggacatcatgaataaaccaccc
cggaacccgaaggaacccctgatcagcggatggctctttttccgttacctggccattggc
tgttacgttggcgctgctacggtgggtgctgctgcctggtggttcattgctgccgatgga
ggtccaagagtgtccttctaccagctgagccacttcctacagtgtaaagatgacaacccg
gattttgaaggagtggattgtgcaatcttcgagtccccgtacccgatgacaatggcgctg
tctgttcttgtaaccatagagatgtgtaacgccctcaacagcttgtctgaaaaccagtcc
ctgctgaggatgcccccctgggagaacatctggctcgtgggctccatctgcctgtccatg
tcgctccacttcctcatcctctacgtggaaccgttgccacttattttccagatcacaccg
ctgaatttgacccagtggctgatggtgctgaaaatctccttgcctgtgattctaatggac
gagacactcaagtttgtggcccgcaactacctggaacctgcaatactggagtaa
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