Ursus americanus (American black bear): 123779529
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Entry
123779529 CDS
T07931
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar01521
EGFR tyrosine kinase inhibitor resistance
uar01522
Endocrine resistance
uar01524
Platinum drug resistance
uar04010
MAPK signaling pathway
uar04012
ErbB signaling pathway
uar04020
Calcium signaling pathway
uar04066
HIF-1 signaling pathway
uar04151
PI3K-Akt signaling pathway
uar04510
Focal adhesion
uar04520
Adherens junction
uar04530
Tight junction
uar05200
Pathways in cancer
uar05205
Proteoglycans in cancer
uar05206
MicroRNAs in cancer
uar05212
Pancreatic cancer
uar05213
Endometrial cancer
uar05215
Prostate cancer
uar05219
Bladder cancer
uar05223
Non-small cell lung cancer
uar05224
Breast cancer
uar05226
Gastric cancer
uar05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123779529 (ERBB2)
04012 ErbB signaling pathway
123779529 (ERBB2)
04066 HIF-1 signaling pathway
123779529 (ERBB2)
04020 Calcium signaling pathway
123779529 (ERBB2)
04151 PI3K-Akt signaling pathway
123779529 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
123779529 (ERBB2)
04520 Adherens junction
123779529 (ERBB2)
04530 Tight junction
123779529 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123779529 (ERBB2)
05206 MicroRNAs in cancer
123779529 (ERBB2)
05205 Proteoglycans in cancer
123779529 (ERBB2)
05230 Central carbon metabolism in cancer
123779529 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
123779529 (ERBB2)
05226 Gastric cancer
123779529 (ERBB2)
05219 Bladder cancer
123779529 (ERBB2)
05215 Prostate cancer
123779529 (ERBB2)
05213 Endometrial cancer
123779529 (ERBB2)
05224 Breast cancer
123779529 (ERBB2)
05223 Non-small cell lung cancer
123779529 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123779529 (ERBB2)
01524 Platinum drug resistance
123779529 (ERBB2)
01522 Endocrine resistance
123779529 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uar01001
]
123779529 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
uar04147
]
123779529 (ERBB2)
04090 CD molecules [BR:
uar04090
]
123779529 (ERBB2)
Enzymes [BR:
uar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
123779529 (ERBB2)
Protein kinases [BR:
uar01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
123779529 (ERBB2)
Exosome [BR:
uar04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
123779529 (ERBB2)
CD molecules [BR:
uar04090
]
Proteins
123779529 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Kinase-like
Motif
Other DBs
NCBI-GeneID:
123779529
NCBI-ProteinID:
XP_045633708
LinkDB
All DBs
Position
Unknown
AA seq
1260 aa
AA seq
DB search
MELAAWCRWGLLLALLPSGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQACQVVQGNL
ELTYLPANASLSFLQDIQEVQGYVLIAHSQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
EPPEGDTSVAGATPGGLRELQLRSLTEILKGGVLIQRNPQLCHQDTILWKDIFHKNNQLA
LTLIDTNRSRACQPCSPACKDPHCWGASSGDCQSLTRTVCAGGCARCKGPKPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSRPCARVCYGLGMEHLREARAVTSAN
IQEFAGCKKIFGSLAFLPESFEGDPASNTAPLQPEQLRVFEALEEITGYLYISAWPDSLP
NLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELGSGLALIHRNARLCFIHTV
PWEQLFRNPHQALLHSANRPEAECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQEC
VEECRELHGLPREYVKDRYCLPCHPECRPQNGSVTCFGSEADQCVACAHYKDPPSCVARC
PSGVKPDLSFMPIWKFADEEGTCQPCPINCTHSCGDLDERGCPAEQRASPVTSIIAAVVG
ILLAVVMGLVLGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPEPAPGAGGPAHRRHRSSSTRSGGGELTVGLEPSEEEPPKSPLAPSEG
AGSDVFDGDLGMGAAKGLQSLPPQDPSPLQRYSEDPTVPLPPETDGYVAPLTSSPQPEYV
NQPEVWPQPPSPLEGPLPPPRPAGATLERPKTLSPKTLSPGKNGIIKDVFAFGSAVENPE
YLAPRGRAAPQLHPPPAFSPAFDNLYYWDQDPSERGSPPSTFEGTPTAENPEYLGLDVPV
NT seq
3783 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccctccggagcc
gcgggcacccaagtgtgcaccggcacagacatgaagctgcggctccctgccagtcccgag
acccacctggatatgctccgccacctctaccaggcctgtcaagtggtacagggtaacctg
gagctcacctacctgcccgccaatgccagcctgtccttcctgcaggatatccaggaggta
cagggctatgtgctcattgctcacagccaagtgagacaggtcccgctgcagaggctccga
atcgtgcgaggcacccagctctttgaggacaactatgccctggccgtgctggacaatgga
gagccgcccgagggggacacctctgtggcaggggctaccccaggagggctgcgggagctg
cagcttcgaagcctcacagagatcctgaagggaggggtcttgattcagcggaacccacag
ctctgccaccaggacacgattttgtggaaggacatcttccacaagaacaaccagctggcc
ctcacgctgatagacaccaaccgctctcgggcctgccaaccctgttctccagcctgtaaa
gacccccactgctggggagcaagttccggggactgtcagagcttgacacgaaccgtctgt
gccggcggctgtgcccgctgcaagggcccaaaacccactgactgctgccatgagcagtgc
gcggctggctgcacgggccccaagcactcggactgcctggcctgccttcacttcaaccac
agtggcatctgtgagctgcactgcccagccctggtcacctacaacacggacacgttcgaa
tccatgcccaaccctgagggccgatacaccttcggtgccagctgtgtgaccgcctgtccc
tacaactacctgtccacggacgtgggatcctgcaccctggtctgtcccctgaacaaccaa
gaggtgacggctgaggatggcacccagcggtgtgagaaatgcagcagaccctgtgcccga
gtgtgctatggtctgggcatggagcacctgcgggaggcgagggcggtcaccagcgccaac
atccaagagttcgccggctgcaagaagatctttgggagcctggcgtttctgccagagagc
ttcgagggagacccagcctccaacactgcccccctgcagcctgaacagctcagagtgttc
gaggccctggaggagatcacaggttacctgtatatctcagcgtggccggacagcttgcct
aacctcagtgtcttccagaacctgcgagtaatccggggacgagttctgcatgatggcgcc
tactcgctgaccctgcaagggctgggcatcagctggctggggctgcgctcgctgcgggaa
ctgggcagcgggctggccctcatccaccgcaacgcccgcctctgcttcatccacacggtg
ccctgggagcagctcttccggaacccccaccaagccctgctgcacagtgccaaccggccg
gaggccgagtgcgtgggcgagggcctggcctgctacccgctgtgcgcccatgggcactgc
tggggtccggggcccacccagtgcgtcaactgcagccaattccttcggggccaggagtgc
gtggaggaatgccgagaactgcacgggctaccccgggaatatgtgaaggacagatactgt
ctgccatgccaccccgagtgtcggccccagaatggctcagtgacctgctttgggtcggag
gctgaccagtgtgtggcctgcgcccactacaaggaccctccctcctgcgtggctcgctgc
cccagtggtgtgaaacccgacctctctttcatgcccatttggaagtttgcagatgaggag
ggcacatgccagccgtgccccatcaactgcacccactcctgtggggacctggacgagagg
ggctgccccgccgaacagagagccagccctgtgacatccatcattgccgctgtggtgggc
attctgctggccgtggtcatggggctggtcctcggcatcctgatcaagcgaaggcgacag
aagatccgcaagtacacgatgcggaggttgctgcaggaaaccgagctggtggagccgctg
acgcctagcggagcgatgcccaaccaggctcagatgcggatcctgaaagagacagagctg
aggaaggtgaaggtgcttggatccggagcttttggcacggtctacaagggcatctggatc
cctgacggggaaaatgtgaaaatcccagtggccatcaaagtgttgagggaaaacacatct
cccaaagccaacaaagaaatcttggacgaagcgtatgtgatggctggagtgggctcccca
tatgtgtcccgccttctgggcatctgcctgacgtccacggtgcagctggtgacacagctt
atgccctatggctgcctcttagaccacgtccgagagcaccgtgggcgtctgggctcccag
gacctcctgaactggtgtgtgcagatcgccaaggggatgagctacttggaggacgtccgg
ctcgtgcacagggacctggctgcccggaacgtgctggtcaagagtcccaaccatgtcaag
attacagacttcgggctggctcggttgctggacattgatgagaccgagtaccacgcggat
gggggcaaggtgcccatcaagtggatggcgctggagtccattctccgccggcggttcacc
caccagagtgacgtgtggagctacggtgtgactgtgtgggaactgatgacttttggggcc
aaaccttacgatgggatcccagcccgagagatccctgacctgctggagaagggggaacgg
ctgccccagccccccatctgcaccatcgacgtctacatgattatggttaaatgttggatg
atagactctgaatgtcgaccacggttccgggagttggtggccgaattctcccgcatggcc
agggacccccagcgctttgtggtcatccagaatgaagacctgggccccgccagcccattg
gacagcaccttctaccgttcgctgctggaagatgatgacatgggggacctggtggatgcc
gaggagtacctggtgccccagcaggggttcttctgcccagaacctgcccctggagcgggg
ggcccggcccaccgcaggcaccgcagctcgtccaccaggagtggcggtggtgagctgaca
gtgggactggagccctctgaggaggagccccccaagtctccactggccccgtcagagggg
gctggctctgacgtgtttgatggtgacttgggaatgggggcagccaaggggctgcagagc
cttcccccccaggacccgagccctctacagcggtacagcgaggaccctacagtacccctg
ccccctgagactgatggctacgttgcccccctgaccagcagccctcagcctgaatacgtg
aaccagccagaggtttggccgcagcccccctcacccctagaaggccctctgcctcctcct
cgacctgctggtgccaccctggaaaggcccaagactctgtcccccaagaccctctcccct
ggcaagaatgggatcatcaaagacgtttttgcctttgggagtgcggtggagaaccctgag
tacttggcaccccggggcagggctgcccctcagctccaccctcctccagccttcagccca
gcctttgacaacctctattactgggaccaggacccatcagagcggggctctccacccagt
acctttgaagggacccctacagcagagaaccctgagtacctgggcctggacgtgccagtg
tga
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integrated database retrieval system
