Ursus americanus (American black bear): 123779772
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Entry
123779772 CDS
T07931
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar00260
Glycine, serine and threonine metabolism
uar00630
Glyoxylate and dicarboxylate metabolism
uar00670
One carbon pool by folate
uar01100
Metabolic pathways
uar01200
Carbon metabolism
uar01230
Biosynthesis of amino acids
uar01240
Biosynthesis of cofactors
uar01523
Antifolate resistance
uar04981
Folate transport and metabolism
Module
uar_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
123779772 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
123779772 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
123779772 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
123779772 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
123779772 (SHMT1)
Enzymes [BR:
uar01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
123779772 (SHMT1)
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Paralog
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Motif
Pfam:
SHMT
DegT_DnrJ_EryC1
Motif
Other DBs
NCBI-GeneID:
123779772
NCBI-ProteinID:
XP_045634237
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All DBs
Position
Unknown
AA seq
533 aa
AA seq
DB search
MMTQVNGAPKDADLWSSHEKMLAQPLKDSDTEVYNIIKKESHRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELELLCQKRALQVYGLDPECWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
INYGQLEENARLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYLLADMAHISGLVAAGV
VPSPFEHCHVVSTTTHKTLRGCRAGMIFYRKGVRSVDPKTGKETLYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTPEFRLYQRQVVANCRVLAETLMELGYKVVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKEFQK
VAHFIHRGRWEVNTGLPAREISSSEGGPHLPTGSPPAECYQLWHWGAVCWPSENLNWAVL
LFEMETYDTLNIATKKLKARWEMTGGQSRSISQFWCNSCNFSTAGNHRQVTDF
NT seq
1602 nt
NT seq
+upstream
nt +downstream
nt
atgatgactcaagtcaacggagctcccaaggatgccgacctgtggtcctcgcatgaaaaa
atgctggcgcagcccctgaaagacagtgacaccgaggtttacaacatcatcaagaaggag
agtcaccgccagagggtcgggctggagctgatcgcctccgagaatttcgccagccgagca
gttttggaggccctaggctcttgcttaaataacaagtactccgaggggtacccaggccag
aggtactatggcgggaccgagttcatcgacgagctggagctcctgtgtcagaagcgagcg
ctgcaggtctacggtctggaccccgagtgctggggggtcaatgtccagccctactcaggc
tcccctgccaacttcgcagtctataccgccctggtggagccccacgggcgcatcatgggc
ctcgacctgcccgatggcggccacctgacccacggcttcatgacggacaagaagaaaatc
tctgccacgtccatcttttttgaatctatgccctataaggtaaacccagacaccggctac
atcaactatggccaactggaggaaaacgcccgcctcttccacccgaagctgattatcgca
ggaaccagctgctactcccgaaacctggactacgctcgcctgaggaagatcgcggacgac
aacggggcgtatctcctggccgacatggcgcacatcagcgggctggtggcggctggtgtg
gtgccctccccctttgagcactgccacgtggtgtccaccaccacccacaaaactctgaga
ggttgccgggccggcatgatcttctacaggaaaggagtgcgcagcgtggatcccaagacc
ggcaaagagactctctacaacctggagtcacttatcaactcggccgtgttcccgggcctg
cagggcggtccccacaaccatgccattgctggggtcgctgtggccctgaagcaagctatg
actccggaattccgactctaccaacgccaggtggtggccaactgccgggttctggctgag
accctgatggagctgggctacaaagtggtgacaggtggttctgacaaccatttgatcctt
gtggatctccgttccaaaggcacagatggtggaagggctgagaaggttctagaagcctgt
tctattgcctgtaataagaacacctgtccaggtgacaaaagcgcattgcggcccagcgga
ctgcgtctggggacgccagcactgacatcccgaggacttttggaaaaagagttccagaaa
gtagcccactttattcacagagggagatgggaagttaacaccggactgccggcgcgggag
atcagttcctctgaaggcggtccacacttgccgacgggctccccaccagctgagtgttac
caactgtggcactggggtgcagtctgttggccttccgagaatttgaactgggctgtgttg
ttgtttgagatggaaacctacgataccttgaatatagcaacaaagaagttaaaagctaga
tgggaaatgacaggggggcaatcacggtccatttcccaattctggtgcaattcatgtaac
ttcagcactgcaggaaatcacagacaagtcactgatttttaa
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