KEGG   Ursus americanus (American black bear): 123780311
Entry
123780311         CDS       T07931                                 
Symbol
PLAT
Name
(RefSeq) tissue-type plasminogen activator
  KO
K01343  tissue plasminogen activator [EC:3.4.21.68]
Organism
uar  Ursus americanus (American black bear)
Pathway
uar04371  Apelin signaling pathway
uar04610  Complement and coagulation cascades
uar05202  Transcriptional misregulation in cancer
uar05215  Prostate cancer
uar05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:uar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    123780311 (PLAT)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    123780311 (PLAT)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    123780311 (PLAT)
  09162 Cancer: specific types
   05215 Prostate cancer
    123780311 (PLAT)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    123780311 (PLAT)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:uar01002]
    123780311 (PLAT)
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:uar00536]
    123780311 (PLAT)
Enzymes [BR:uar01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.68  t-plasminogen activator
     123780311 (PLAT)
Peptidases and inhibitors [BR:uar01002]
 Serine peptidases
  Family S1: chymotrypsin family
   123780311 (PLAT)
Glycosaminoglycan binding proteins [BR:uar00536]
 Heparan sulfate / Heparin
  Coagulation and fibrinolysis
   123780311 (PLAT)
SSDB
Motif
Pfam: Trypsin Kringle fn1 EGF DUF1986 Trypsin_2 hEGF cEGF
Other DBs
NCBI-GeneID: 123780311
NCBI-ProteinID: XP_045635104
LinkDB
Position
Unknown
AA seq 563 aa
MNTTRRELVCVLLLCGAALTLSSQEIHPRFRRGARSYRGSCRDEKTQTLHAQNESWLRPG
LRGNRVEYCRCVGGRPHCHSVPVKSCSEPRCFNGGMCRQALYFSDFVCQCPEGFLGKRCE
IDASATCYKDQGITYRGTWSTAESGAECVNWNSSVLALKPYSGRRPDAVGLGLGNHNYCR
NPDRDSRPWCYVFKAGKYTSEFCSTPACPKEKNEDCYFGKGLAYRGTYSLTTSGASCLQW
SSIVLTGKIYTAWKTNSQALGLGNHNYCRNPDGDAKPWCHVLKDRKLTWEYCDVPQCSTC
GLRQYKQPQFRIKGGLYTDITSHPWQAAIFVKNRRSPGERFFCGGILISSCWVLSAAHCF
QERYDPHHLRVVLGRTYREVPGEEEQKFEVEKYIVHEAFDDDTYNNDIVLLKLQSDSLHC
AQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSERLKEAHVRLYPSSRCTSR
HLFNKTVTNNMLCAGDTRSGGNQANLHDACQGDSGGPLVCVQDNRMTLVGIISWGIGCGQ
KDVPGIYTKVINYLDWIQNNMRP
NT seq 1692 nt   +upstreamnt  +downstreamnt
atgaatacaacgaggagagagctggtgtgcgtcctgctgctttgcggagccgccctcacc
ttgtccagccaggaaatccacccccgattcagaagaggagccagatcttacagagggagc
tgcagagatgagaagacgcagacgctgcacgcgcagaacgagtcgtggctgcgcccgggg
ctgcgcggcaaccgcgtggagtactgccgctgcgtgggcggccgcccgcactgccactcg
gtgcccgtcaaaagttgcagcgagccgaggtgcttcaacggcgggatgtgtcggcaggct
ctctatttctccgattttgtctgccagtgccctgaagggtttctgggcaagcgctgcgaa
atagatgccagtgccacctgctataaggaccagggtatcacctacaggggcacgtggagc
acagcggagagcggggccgagtgtgtcaactggaacagcagcgtgctggccctgaagccc
tacagcgggcggaggcccgacgcggtcgggctgggcctcgggaatcacaattattgcaga
aacccagaccgagactcaaggccctggtgctatgtcttcaaggcggggaagtacactagt
gagttctgcagcacgccagcctgccccaaggaaaaaaatgaggactgctactttggaaaa
gggttggcataccgtggcacctacagcctcaccacatctggtgcctcctgcctccagtgg
agttccatagtcctaacaggcaagatctacacagcatggaagaccaattctcaggccctg
ggcctgggcaaccacaattactgccggaacccagatggggatgccaagccttggtgccac
gtgctgaaggaccgcaagttgacgtgggaatactgtgacgtgccccagtgctccacctgt
ggcctgagacagtacaagcagccgcagtttcgcattaaaggagggctctacacggacatc
acctctcacccgtggcaggctgccatctttgtcaagaacaggaggtcaccaggagagagg
tttttttgtggcggaatactgatcagttcctgctgggtcctgtctgctgcccactgcttc
caggagaggtatgatccccaccaccttagggtggtcttgggcagaacataccgagaggtc
cctggagaggaggagcagaaatttgaagtcgaaaaatacatcgtccatgaggcatttgat
gacgacacttacaacaatgatatcgtcctgctgaaactgcagtcggattcgctgcactgt
gcccaggagagcgacgctgtccgcaccgtgtgtctccccgaggccaacctgcagctgccc
gactggacagaatgcgagctgtctggctacggcaagcacgaggcgtcttctcctttctat
tctgagcggctgaaggaggctcatgtccggctgtacccatccagccgctgcacatcacgg
cacctgtttaacaaaaccgtcacgaacaacatgctgtgcgccggggacacgcgaagtggt
gggaaccaggcaaacctgcacgacgcctgccagggtgactcgggcggccccttggtgtgt
gtgcaggacaaccgcatgactttggttggcatcatcagttggggcatcggctgcgggcag
aaagatgttcctggtatatataccaaggttattaattacctagactggattcaaaacaac
atgcgcccgtga

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