KEGG   Ursus americanus (American black bear): 123780649
Entry
123780649         CDS       T07931                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
uar  Ursus americanus (American black bear)
Pathway
uar04010  MAPK signaling pathway
uar04022  cGMP-PKG signaling pathway
uar04137  Mitophagy - animal
uar04141  Protein processing in endoplasmic reticulum
uar04151  PI3K-Akt signaling pathway
uar04210  Apoptosis
uar04211  Longevity regulating pathway
uar04261  Adrenergic signaling in cardiomyocytes
uar04668  TNF signaling pathway
uar04720  Long-term potentiation
uar04722  Neurotrophin signaling pathway
uar04725  Cholinergic synapse
uar04728  Dopaminergic synapse
uar04911  Insulin secretion
uar04912  GnRH signaling pathway
uar04915  Estrogen signaling pathway
uar04918  Thyroid hormone synthesis
uar04922  Glucagon signaling pathway
uar04925  Aldosterone synthesis and secretion
uar04926  Relaxin signaling pathway
uar04927  Cortisol synthesis and secretion
uar04928  Parathyroid hormone synthesis, secretion and action
uar04932  Non-alcoholic fatty liver disease
uar04934  Cushing syndrome
uar04935  Growth hormone synthesis, secretion and action
uar05010  Alzheimer disease
uar05012  Parkinson disease
uar05014  Amyotrophic lateral sclerosis
uar05020  Prion disease
uar05022  Pathways of neurodegeneration - multiple diseases
uar05030  Cocaine addiction
uar05031  Amphetamine addiction
uar05034  Alcoholism
uar05161  Hepatitis B
uar05163  Human cytomegalovirus infection
uar05166  Human T-cell leukemia virus 1 infection
uar05203  Viral carcinogenesis
uar05207  Chemical carcinogenesis - receptor activation
uar05215  Prostate cancer
uar05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:uar00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    123780649 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    123780649 (ATF4)
   04022 cGMP-PKG signaling pathway
    123780649 (ATF4)
   04151 PI3K-Akt signaling pathway
    123780649 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    123780649 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    123780649 (ATF4)
   04922 Glucagon signaling pathway
    123780649 (ATF4)
   04915 Estrogen signaling pathway
    123780649 (ATF4)
   04926 Relaxin signaling pathway
    123780649 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    123780649 (ATF4)
   04918 Thyroid hormone synthesis
    123780649 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    123780649 (ATF4)
   04925 Aldosterone synthesis and secretion
    123780649 (ATF4)
   04927 Cortisol synthesis and secretion
    123780649 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    123780649 (ATF4)
   04728 Dopaminergic synapse
    123780649 (ATF4)
   04720 Long-term potentiation
    123780649 (ATF4)
   04722 Neurotrophin signaling pathway
    123780649 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    123780649 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    123780649 (ATF4)
   05203 Viral carcinogenesis
    123780649 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    123780649 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    123780649 (ATF4)
   05161 Hepatitis B
    123780649 (ATF4)
   05163 Human cytomegalovirus infection
    123780649 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    123780649 (ATF4)
   05012 Parkinson disease
    123780649 (ATF4)
   05014 Amyotrophic lateral sclerosis
    123780649 (ATF4)
   05020 Prion disease
    123780649 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    123780649 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    123780649 (ATF4)
   05031 Amphetamine addiction
    123780649 (ATF4)
   05034 Alcoholism
    123780649 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123780649 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    123780649 (ATF4)
   04934 Cushing syndrome
    123780649 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:uar03000]
    123780649 (ATF4)
Transcription factors [BR:uar03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    123780649 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 DUF4407 MCU KIF21A Asd-4 AAA_13 Nop53 bZIP_Maf OVT1 DUF3450 Laminin_II
Other DBs
NCBI-GeneID: 123780649
NCBI-ProteinID: XP_045635605
LinkDB
Position
Unknown
AA seq 351 aa
MAEMSFLNSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
WLAVDGLVSASDNGKEDAFSGTDWMVEKMDLKEFDFDSLFSIDDLETMPDELLATLDDTC
DLFDPLVQETNKEPPQSVNPIGHLPESLPKTDQIAPFTFLQPLPLSPGALSSTPDHSFSL
ELGSEVDISEGDRKSDSTAYITVIPQCIKEEDAPSDNDSGICMSPESYLGSPQHSPSTSR
GSPNRSLLSPGSHCGSARPKPYDPPGEKTAAKVKVEKLDKKLKKMEQNKTAATRYRQKKR
AEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKAREKKRVP
NT seq 1056 nt   +upstreamnt  +downstreamnt
atggccgagatgagtttcctgaacagcgaggtgttggtgggggacttgatgtcccccttc
gaccagtcgggtttgggggctgaggagagcctgggtctcttagacgactacctggaggtg
gccaagcacttcaaacctcatgggttctccagcgacaaggctaaggcgggctcctccgaa
tggctggctgtggatgggttggtcagtgcctcagacaacggcaaggaggatgccttttcc
gggacagattggatggtggagaaaatggatctgaaggagtttgattttgattctctgttc
agtatagatgacctggaaaccatgccagatgagcttttggccacgttggatgacacgtgt
gatctctttgaccccctagtccaggagacgaataaggagcccccccagagcgtgaaccca
attggccatctcccagaaagtttaccaaaaacagaccagattgccccctttaccttcctg
caaccacttccactttccccaggggccctgtcctccactccagatcattcttttagttta
gagctaggcagtgaagtggatatttctgaaggagatagaaagtcagactctactgcctac
attaccgtgatccctcagtgcataaaggaggaggatgccccctcagataatgacagtggc
atctgtatgagtcctgagtcctatctggggtccccccagcatagtccctctacctccagg
ggctctccaaataggagcctgctgtctccaggttcccattgtggttctgcccgccccaaa
ccctatgaccctcctggagagaagacggcagcaaaagtaaaggtcgagaaactagataag
aagctgaaaaagatggagcagaacaagactgcagccactaggtaccgccagaagaagagg
gcagagcaggaggccctcactggcgagtgtaaagagctggaaaagaagaatgaggctctg
aaagagagggcagattctttagccaaggagatccagtatctgaaagatttgatagaagag
gtccgaaaggcaagggagaagaaaagggtcccctag

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