Ursus americanus (American black bear): 123781045
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Entry
123781045 CDS
T07931
Symbol
GNE
Name
(RefSeq) bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X1
KO
K12409
bifunctional UDP-N-acetylglucosamine 2-epimerase / N-acetylmannosamine kinase [EC:
3.2.1.183
2.7.1.60
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar00520
Amino sugar and nucleotide sugar metabolism
uar00541
Biosynthesis of various nucleotide sugars
uar01100
Metabolic pathways
uar01250
Biosynthesis of nucleotide sugars
Module
uar_M00955
CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
123781045 (GNE)
00541 Biosynthesis of various nucleotide sugars
123781045 (GNE)
Enzymes [BR:
uar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.60 N-acylmannosamine kinase
123781045 (GNE)
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.183 UDP-N-acetylglucosamine 2-epimerase (hydrolysing)
123781045 (GNE)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Epimerase_2
ROK
Hexokinase_1
FGGY_N
DRTGG
Glucokinase
Motif
Other DBs
NCBI-GeneID:
123781045
NCBI-ProteinID:
XP_045636286
UniProt:
A0A452SPS8
LinkDB
All DBs
Position
Unknown
AA seq
722 aa
AA seq
DB search
MEKNGNNRKLRVCVATCNRADYSKLAPIMFGIKMEPEFFELDVVVLGSHLIDDYGNTYRM
IEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALA
TSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILL
AGCPSYDKLLSAKNKDYMSVIRMWLGDDVKSKDYIVALQHPVTTDIKHSIKMFELTLDAL
ISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGN
SSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKI
YGDGNAVPRILKFLKSIDLQEPLQKKFCFPPVKENISQDIDHILETLSALAVDLGGTNLR
VAIVSMKGEIVKKYTQFNPKTYEERINLILQMCVEAAAEAVKLNCRILGVGISTGGRVNP
REGIVLHSTKLIQEWNSVDLRTPLSDTLHLPVWVDNDGNCAALAERKFGQGKGLENFVTL
ITGTGIGGGIIHQHELIHGSSFCAAELGHLVVSLDGPDCSCGSHGCIEAYASGMALQREA
KKLHDEDLLLVEGMSVPKDEAVGAVHLIQAAKLGNAKAQSILRTAGTALGLGVVNVLHTI
NPSLVILSGVLASHYVHTVKDVIRQQALSSVQDVDVVVSDLADPALLGAASMVLDYTTRR
IC
NT seq
2169 nt
NT seq
+upstream
nt +downstream
nt
atggagaagaatgggaataaccgaaagcttcgggtttgtgttgctacttgcaaccgtgct
gattattctaaacttgccccgatcatgtttggcattaaaatggaacctgagttctttgaa
cttgatgtggtggtacttggctctcacctgatagatgactatgggaacacgtaccgcatg
attgaacaagatgactttgacattaacacgaggctacacacgatcgttagaggggaagac
gaggcagccatggtggaatcagtaggcttggccctagtgaagctaccagatgtccttaat
cgcttgaaacctgatatcatgatagttcatggagacaggtttgatgccctggctctggcg
acatctgccgccttgatgaatatccgaatccttcacattgaaggtggggaagtcagtggg
accatcgacgattccatcagacatgccataacaaaactggcgcattaccacgtatgctgc
acccgaagtgcagagcaacacctgatatccatgtgtgaggaccatgaccgcatccttctg
gcgggctgcccttcctatgacaagctgctctctgccaagaacaaagactacatgagcgtc
attcggatgtggttaggtgatgatgtaaaatctaaagattacattgttgcgctgcagcac
cccgtgaccactgacattaagcattccattaaaatgtttgaattaacattggatgcgctt
atctcatttaacaagcggaccctagttctgtttccaaacattgatgcagggagcaaggag
atggttcgagtgatgcggaagaagggcatagagcaccatcccaatttccgtgcagttaaa
catgtcccatttgaccagtttatacagttggtcgcccatgctggttgtatgattgggaac
agcagctgtggagtacgcgaggttggagcttttggaacacctgtgatcaatctaggaaca
cgtcagattggaagagaaacaggggagaacgtccttcatgtccgggatgctgatacccaa
gacaaaatactgcaagcactgcaccttcagtttggtaaacagtacccttgttcaaagatc
tatggggatggaaatgctgttccgaggattctgaagtttctcaaatctattgatcttcaa
gagccactacaaaagaaattctgctttcctcccgtgaaggagaatatctctcaagacatt
gaccatattcttgaaactctaagtgccttggctgttgatctcggtgggacaaacctccga
gttgcaatagtcagcatgaagggtgaaattgttaagaagtatactcagttcaatcctaaa
acctatgaagagaggattaatttaatcctacagatgtgtgtggaagctgcagcggaagct
gtaaaactgaactgcagaattttgggagtaggtatttctacgggtggccgtgtaaatcct
cgggaaggaattgtgctgcattcaaccaaactgattcaagaatggaactccgtggacctc
aggacccccctctctgacaccttgcatctccccgtgtgggtggacaatgatggcaattgt
gctgccctggcggaaaggaaatttggccaaggaaagggcctggaaaactttgtgaccctt
atcacaggcacaggaattggcggggggatcatccatcagcacgagctgatccacggaagc
tccttctgtgccgcagaacttggccaccttgttgtgtctctggatgggcctgattgctcc
tgcggaagtcacgggtgtattgaagcctacgcctctggcatggccttgcagagggaagca
aagaagctacatgatgaggacctgctcttggtggaagggatgtccgtgccgaaagacgag
gccgtgggcgcggtccacctcatccaagctgcaaaacttggcaatgcgaaggcccagagc
atcctgagaacagctggaacggctttgggtcttggggtggtgaacgtcctccacaccata
aacccttcccttgtgatcctctccggggtcctagccagtcactacgtccacaccgtcaaa
gacgtcatccgccagcaagccctgtcctcggttcaggacgtggacgtggtggtttcggat
ctggcggaccctgccctgctcggtgccgccagcatggttctggactacacaactcgcagg
atctgctag
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