Ursus americanus (American black bear): 123781644 Help Entry 123781644         CDS       T07931                                  Symbol A2M Name (RefSeq) alpha-2-macroglobulin   KO K03910   alpha-2-macroglobulin Organism uar  Ursus americanus (American black bear) Pathway uar04610   Complement and coagulation cascades Brite KEGG Orthology (KO) [BR:uar00001]  09150 Organismal Systems   09151 Immune system    04610 Complement and coagulation cascades     123781644 (A2M)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:uar01002]     123781644 (A2M)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:uar04131]     123781644 (A2M)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:uar04147]     123781644 (A2M) Peptidases and inhibitors [BR:uar01002]  Peptidase inhibitors   Family I39: alpha2M family    123781644 (A2M) Membrane trafficking [BR:uar04131]  Autophagy   Chaperone mediated autophagy (CMA)    Selective cargos     123781644 (A2M) Exosome [BR:uar04147]  Exosomal proteins   Exosomal proteins of colorectal cancer cells    123781644 (A2M) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TED_complement A2M_BRD A2M MG4 A2M_recep MG3 MG2 SVA Big_1 Motif Other DBs NCBI-GeneID:  123781644 NCBI-ProteinID:  XP_045637241 LinkDB All DBs Position Unknown AA seq 1500 aa AA seqDB search MFGTRPVAGSRVNTVWSPQRPSPCSMGKNKLFHPNLILLLLVFLPADASVSGKPQYMVLV PSLLHSETPEKGCLLLSYLNETVTVSASLESLRENRSLFTDLVVEKDLFHCVSFTVPRSP SNEEVMFLTIQVKGSTQEFKRRTTVVVKNQESLVFVQTDKPIYKPGQTVKFRIVSLDENF HPLNELIPLVYIQDPKGNRITQWQKLKLENGLKQLSFALSSEPFQGSYKVVVRKESGGIT EHAFTVEEFVLPKFEVQITMPRIITILEEDVNVSVCGLYTYGKPVPGHMTMRVCRKYSNP SNCYSGESQAVCEKFSHQLNSQGCFSQQVKTKIFQMKRQGYEMKLEAEAKIQEEGTEVEL TGKGSTEITRTITKLSFVKVDPYFRQGIPFFGQVQLLDGKGVPMPDELVFITANEANYNS NATTDEHGLVQFSINTTDITGTSLTVRVKHKDSSPCYGYQWLLAEHEEAHHTANLVFSLS KSFVRLEPLPRELPCGQTQTVQAHYILNARVLQELNELVFYYLIMAKGGVVLNGAHMLPV KQGDMKGHFSVSIPVESDIAPVARMLIYAILPDGEVIGDSAKYKVENCLANKVDLSFRPT QSLPASHAHLQVSASPQSLCALRAVDQSVLLMKPEAELSAASVYNLLPVKDLSGFPGSLN RQEEDDRDCINRHNVYINGVMYSPVSNTNEKDMYSFLQDMGLKVFTNTKIRKPKVCSQPE HEAVYSSRRLFTSPVVSELQRGHELTKMVHVSEPLTETVRKYFPETWIWDLVAVDSSGVA EVGVIVPDTITEWKAGALCLSNDTGLGLSLPASLRAFQPFFVELTMPYSVIRGEAFTLKA TVLNYLPKCIQVGVQLDPNPAFLVQEKEQESHCICGNGRHTVSWAVTPKALGNVNFTVSA EALESQEPCGTEVAVVPEFGKKDTIIKSLLVEPEGLEKEVTFNSLLCPSGVEVSEQLPLK LPENVVEESARASVSVLGDLLGSAMHNIQNLLRMPYGCGEQNMVLFAPNIYVLNYLNETH QLTPEVMSKAVGYLNTGYQRQLKYKHHDGSYSTFGENYGKSEGNTWLTAFVLKSFAQARA YIFIDEAHITQALTWLSQKQKDSGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPL PATHPVVRNALFCLESAWKSAKERPHGKHVYTKALLAYAFALAGNQDKRRETLDLLHGEA VKEDNSVHWERPQKPRAPVGHFYQPPAPSAEVEMTSYVLLAYLTAQPAPTSEELTSAARI VKWITKQQNSQGGFSSTQDTVVALQALSRYGTATFTRTGKPAQVTVQYSRTFVTKFQVDD DNRLLLQQTSLPKVPEEYTMTVTGEGCVYLQTSLKYNILPEKAEFPFALEVQTVPETCDG PKAHTSFQISLNVSYIGSRPVSNMVIIDAKMVSGFIPLKPTVKMLERSNHVSRTEVSNNH VLIYLDKVTNQTLSLSFRVLQDVPVRELKPAIVKVYDYYETDEFAIAEYSAPCSQDHGNA NT seq 4503 nt NT seq  +upstreamnt  +downstreamnt atgtttgggaccagaccagttgcaggaagcagggtcaatacagtctggtctcctcagaga ccttctccctgcagcatggggaagaacaaactctttcatccaaatcttattctcctcctt ctggtcttcctgcctgcagatgcctcagtctctggaaaaccgcagtacatggtcctggtc ccctccctgctccactctgaaacccctgagaaaggctgccttcttctgagctacctgaat gagacagtgactgtaagtgcttccctggagtctctcagggagaacaggagcctcttcact gacctggtggtggagaaggacttattccactgcgtctccttcactgtcccaagatctcca tccaatgaggaagtcatgttcctcactatccaagtgaaaggatcaacccaagaattcaag aggaggaccacagtggtggttaaaaaccaagagagtctggtctttgtccagacagacaaa cccatctacaaaccagggcagacagtgaagttccgtattgtctcattggatgaaaatttt caccccctgaatgagttgattccattagtatacattcaggacccgaaaggaaatcgcatc acccaatggcagaaactcaaattagagaacggtctcaagcaattgagctttgccctctca tccgagccctttcagggctcctataaggtggtggtgcggaaggaatcgggtggaataaca gagcacgccttcaccgtggaggaattcgtgcttcccaagtttgaagtgcaaataacaatg ccaaggataatcactatcttggaagaagacgtgaatgtgtcagtatgtggcctatacaca tatgggaagcctgtcccaggacatatgactatgagagtgtgcagaaagtacagtaaccct tctaactgctatagtggagagtcacaggccgtctgtgagaaattcagtcaccagctaaac agccagggctgcttctctcagcaagtaaaaaccaagatcttccagatgaagagacaaggg tatgaaatgaaacttgaagcggaggccaagatccaagaagaaggaacagaggtagaatta actggaaaaggatccactgaaataacaagaaccataaccaaactctcattcgtgaaagtg gacccatactttagacaagggatccctttctttgggcaggtgcaactattggatgggaaa ggtgtccccatgccagatgaacttgtcttcatcacagcaaatgaagctaactataattcc aatgctaccacagatgagcatggcctggttcagttctctatcaacaccaccgacattacg ggtacctctctcactgtcagggtcaaacacaaggattctagcccctgttacggctaccag tggctgttggcagagcacgaagaagctcatcacaccgctaatcttgtattctccctaagc aagagttttgtccgcctggagcccttgcctcgggaactgccctgcggacaaacccagacg gtccaagcacattatattctgaatgcacgggtcctgcaggagctgaacgagctcgtgttc tattacctgataatggcaaagggaggcgttgtcctaaatggggcacacatgctgcctgtg aaacagggagatatgaaaggccatttttccgtgtccatccctgtggagtcagacattgct ccagttgctcgaatgctcatctacgccattttacctgatggggaagtgattggggattct gcaaaatacaaggttgaaaactgtctagccaacaaggtggacttgagcttccgcccaaca caaagtctcccggcttcccacgcccacctgcaagtttcagcttctcctcagtccctgtgc gccctccgtgccgtggaccaaagtgtgctgctcatgaagcccgaagcagagctgtccgca gcctcggtttataacctgctaccagtgaaggacctcagtggtttccctgggagcttgaat cgtcaggaggaagatgatagagactgtatcaatcgccataatgtctatatcaatggggtc atgtattcccctgtatcaaatacaaatgaaaaagatatgtatagcttcctacaggatatg ggcttaaaggtattcaccaacacaaagattcgtaaacccaaagtatgttcacagcctgaa cacgaggcagtgtactcatctcgaagactattcacttctccagtcgtatctgaattgcaa agaggccatgaacttacaaagatggtccatgtttccgagcctctcaccgagactgtgcga aagtacttccctgagacatggatctgggacttggtggcagtagactcatcaggtgtggct gaagtgggagtaatagtccctgataccatcacagagtggaaggcaggggccctctgcctg tcgaatgacactggacttggtctctctcttcccgcctccctccgagccttccagcccttc tttgtggagctcacaatgccctactctgtgatccgcggagaggccttcacactcaaggcc accgtcctcaactaccttcccaaatgcatccaggttggtgtgcagctagatccgaatcct gcattcctggtccaggagaaggaacaagagtctcactgcatctgtgggaatggccggcac accgtgtcctgggcagtaacgccaaaggcattagggaatgtgaatttcactgtgagtgca gaggcactggagtctcaagagccctgtgggactgaggtggcggtggtccctgagtttgga aagaaagacaccatcattaagtccctgctggttgagcctgaaggactagagaaggaagta acgttcaattccctgctctgtccgtcaggtgttgaggtgtctgaacaattacctttgaag ttgccagagaatgtagtagaagaatcggcccgagcctctgtctcagtattgggagaccta ctgggctctgccatgcacaatatacaaaatctcctccgaatgccctatggctgtggagaa cagaatatggtcctctttgctcccaacatctatgttctgaactatctaaatgaaacacac cagctgactccagaagtcatgtccaaggctgttggctacctcaatactggttaccagaga cagctgaagtacaagcaccatgatggctcctatagcacctttggggagaactatggcaag agtgagggcaatacctggctcactgcctttgtactgaagagttttgcccaggctcgagcc tatatcttcatcgatgaagcacacatcacccaagccctcacctggctctcccaaaagcag aaggacagtggctgtttcaggagttccgggtctctgctcaacaatgccattaagggagga gtggaagacgaagtgaccctctccgcctacatcaccattgcccttctggagatccctctc cccgccactcaccccgttgtccgcaatgccctgttctgcctggagtcagcctggaagtca gcaaaggaaagaccccatggaaagcatgtctacaccaaggcactgctggcctatgctttt gccctggcaggtaaccaggacaagaggagagagacgctcgacttacttcatggggaagct gtgaaggaagataattccgtccactgggagcgacctcagaaacccagggcacccgtgggg catttttaccaacccccggctccctcagctgaggtggagatgacgtcctacgtgctgctg gcttacctcacggcccagcctgcccccacctcagaggagctgacttccgccgcacgcatc gtgaagtggatcacaaagcaacagaattcccaggggggcttctcctccacccaggacaca gtggtggctctccaggccttgtccagatatggaacagccaccttcaccaggactgggaag cccgcacaggtgaccgtccaatattctaggacatttgtcacaaaattccaagtggacgac gacaaccgcctgttactacagcagacctcattgccaaaggtgcctgaggaatacaccatg acggtgacaggagaaggctgtgtctacctccagacatccttgaaatacaacattctgcca gaaaaggcagagttcccatttgctttggaggtgcagacggtgcccgaaacttgtgacgga cccaaagcccacaccagcttccagatctcactgaatgtcagttacatcgggagtcgtccc gtctccaacatggtgattattgatgcgaagatggtgtccggcttcattcccctgaaacca acagtgaaaatgcttgaaagatctaaccacgtgagccgaacagaagtcagcaacaaccat gttttgatttatctggataaggtgacaaatcagacactcagcttgtccttcagggttctg caagatgtcccagtgagagagctgaagccagccatagtgaaagtctatgactactatgag acagatgaatttgcaattgctgagtacagtgctccgtgcagccaagatcatggaaatgct tga

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