Ursus americanus (American black bear): 123782085
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Entry
123782085 CDS
T07931
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.39
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar04022
cGMP-PKG signaling pathway
uar04024
cAMP signaling pathway
uar04062
Chemokine signaling pathway
uar04071
Sphingolipid signaling pathway
uar04270
Vascular smooth muscle contraction
uar04350
TGF-beta signaling pathway
uar04360
Axon guidance
uar04510
Focal adhesion
uar04520
Adherens junction
uar04530
Tight junction
uar04611
Platelet activation
uar04670
Leukocyte transendothelial migration
uar04810
Regulation of actin cytoskeleton
uar04921
Oxytocin signaling pathway
uar05135
Yersinia infection
uar05163
Human cytomegalovirus infection
uar05200
Pathways in cancer
uar05205
Proteoglycans in cancer
uar05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
123782085 (ROCK1)
04071 Sphingolipid signaling pathway
123782085 (ROCK1)
04024 cAMP signaling pathway
123782085 (ROCK1)
04022 cGMP-PKG signaling pathway
123782085 (ROCK1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
123782085 (ROCK1)
04520 Adherens junction
123782085 (ROCK1)
04530 Tight junction
123782085 (ROCK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
123782085 (ROCK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
123782085 (ROCK1)
04670 Leukocyte transendothelial migration
123782085 (ROCK1)
04062 Chemokine signaling pathway
123782085 (ROCK1)
09152 Endocrine system
04921 Oxytocin signaling pathway
123782085 (ROCK1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
123782085 (ROCK1)
09158 Development and regeneration
04360 Axon guidance
123782085 (ROCK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123782085 (ROCK1)
05206 MicroRNAs in cancer
123782085 (ROCK1)
05205 Proteoglycans in cancer
123782085 (ROCK1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
123782085 (ROCK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
123782085 (ROCK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uar01001
]
123782085 (ROCK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
uar03036
]
123782085 (ROCK1)
Enzymes [BR:
uar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
123782085 (ROCK1)
Protein kinases [BR:
uar01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
123782085 (ROCK1)
Chromosome and associated proteins [BR:
uar03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
123782085 (ROCK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
Pkinase_C
APH
Motif
Other DBs
NCBI-GeneID:
123782085
NCBI-ProteinID:
XP_045637905
LinkDB
All DBs
Position
Unknown
AA seq
1355 aa
AA seq
DB search
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRSSPNV
DKSLQENLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLEST
VSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLASEKL
AQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKTQTD
KDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLN
HSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL
KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLSLQLEQES
NKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNREYLKKIQELQSEKETLATQLDLAETKAE
SEQLARGLLEEQYFELSQESKKAASRNRQEITDKDHTVSRLEETNSMLTKDIELLRKENE
ELTDKMRRAEEEYKLKKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHKNELQMQL
ASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSIPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSAANQSFRKVVKNTSGKTSS
NT seq
4068 nt
NT seq
+upstream
nt +downstream
nt
atgtcgactggggacagttttgagactcggtttgaaaaaatcgacaacctgctgcgggat
cccaaatcggaagtgaattcagattgtttgctggatggattggatgctttggtatatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttttaagcagatataaa
gacacaataaataaaattagagatttacgaatgaaagcagaagattatgaagtagtgaag
gtgattggtagaggtgcatttggagaagttcaattggtaaggcataaatccaccaggaag
gtatatgctatgaagcttctcagtaaatttgaaatgattaagagatccgattctgctttt
ttttgggaagaaagggacatcatggcttttgctaacagcccttgggtcgtccagcttttt
tatgcattccaagatgatcgttatctctacatggtgatggagtacatgcctggcggagat
cttgtaaacttaatgagcaactatgatgtgcctgaaaaatgggcacgattctatactgca
gaagtagttcttgcattggatgcaatccattccatgggtttcattcatagagatgtgaaa
cctgataacatgctgctggataaatctggacatttgaagttagcagattttggtacttgt
atgaagatgaataaggaaggtatggtacgatgtgatacagcagttggaacacctgattac
atttctcctgaagtattaaaatctcaaggtggtgatggctattatggacgagaatgtgac
tggtggtcagttggggtatttttatatgaaatgcttgtaggtgatacacctttttatgca
gattctctggttggaacttacagtaagattatgaaccataaaaattcacttactttccct
gatgataatgatatatcaaaagaagcaaaaaatcttatttgtgccttccttactgacaga
gaggtgagattagggcgaaatggtgtagaagaaatcaaacgacatctcttcttcaaaaat
gatcaatgggcttgggaaacactcagagacactgtagcaccagttgtacctgatttaagt
agtgacattgatacaagtaattttgatgacttggaagaagataaaggagatgaagaaaca
ttccccatacctaaagcttttgttggcaatcaattaccttttgtaggatttacatattat
agcaatcgtagatacttatcttcagcaaatcctaatgataaccgaagtagccccaatgtg
gataaaagcttgcaggaaaatttgcaaaaaacaatttataagctggaagaacagctgcat
aatgaaatgcaattaaaagatgaaatggagcagaagtgcagaacttcaaacataaaacta
gacaagataatgaaagaattggatgaagaggggaatcaaagaagaaacctagaatctaca
gtgtctcagattgagaaggagaaaatgttgctacagcatagaattaatgagtaccagaga
aaagcagaacaggaaaatgagaagaggaggaatgtagaaaatgaagtttctacattaaag
gatcagttggaagacttgaagaaagtaagtcaaaattcacagcttgctagtgagaagctg
gcgcaattacaaaagcagctagaagaagccaatgacttacttaggacagaatcagacaca
gccgtaagattaaggaagagtcacacagagatgagtaagtcaattagtcagctagagtcc
ctaaacagagaattgcaggagagaaatagaattttagagaattccaagacacagacggac
aaggactattaccagctgcaagctgtattagaagctgaacgaagagacagaggtcatgat
tctgagatgattggagaccttcaagctcgaattacatctttacaagaggaggtgaagcat
ctcaaacataatcttgaaagagtggaaggagaaagaaaagaagctcaagacatgcttaat
cactcagaaaaggaaaaaaataatttagagatagatttgaactataagcttaaatcatta
caacaacgtttagaacaagaggtaaatgaacataaagtaaccaaagctcgtttaactgac
aaacatcaatctattgaagaggcaaagtctgttgcaatgtgtgaaatggaaaaaaagctg
aaggaagagagagaagctcgagagaaggctgaaaatagagttgttcagattgagaagcag
tgttcaatgctagatgttgatctgaaacagtctcagcagaagctcgagcatttgactgaa
aataaagaaaggatggaggatgaagttaagaatctatcccttcaactggagcaggaatca
aacaagcgactgttgttacagaatgaattgaagactcaggcatttgaagcagacaattta
aaaggtctagaaaagcagatgaaacaagaaataaatactttattggaagcaaagagatta
ttagaatttgaattagctcagcttacaaaacagtatagaggaaatgaaggacagatgcgg
gagctacaagatcagcttgaagctgagcagtatttctcgacactttataaaacccaggta
aaggaacttaaggaagaaattgaagaaaaaaacagagaatatttaaagaaaatacaagag
ttacaaagtgaaaaagaaactcttgctactcagttggatctagcagaaacaaaagctgag
tctgagcaattggctcgagggcttctggaagaacagtattttgaattaagccaagaaagc
aagaaagctgcttccagaaataggcaagagattacagataaagatcatactgttagtcgg
cttgaagaaacaaacagcatgttaaccaaagatattgaattattaagaaaagaaaatgaa
gagctaactgataaaatgaggagggcagaggaagaatataaattgaagaaggaggaggag
attagtaatcttaaggctgcctttgaaaagaatatcaatacagaaagaactcttaaaaca
caggctgttaacaagttggcagaaataatgaatcggaaagattttaaaattgatagaaag
aaagctaatacacaggatttgagaaagaaagaaaaggaaaatcgaaagctgcaactggaa
ctcaaccaagaaagagagaaattcaaccagatggtagtgaaacatcagaaggaactgaat
gacatgcaagcgcaattggtagaagaatgtacacataagaatgagcttcagatgcaattg
gctagcaaagagagtgatattgagcaattgcgtgctaaacttttggacctttcggattct
acaagtgttgctagttttcctagtgctgatgaaactgatggaaaccttccagagtcaaga
attgaaggttggctttcaataccaaatagaggaaatatcaaacgatatggctggaagaaa
cagtatgttgtggtaagcagcaaaaaaattttgttctataatgatgaacaagataaggaa
caatccaatccatccatggtattggacatagataaactgtttcacgttcgaccagtaact
caaggagatgtttacagagctgaaactgaagaaattcctaaaatattccagatactatat
gcaaatgaaggcgaatgtagaaaagatgtagagatggaaccagtacaacaagctgaaaag
actaattttcaaaaccacaaaggccatgagttcattcctacactctaccactttcctgcc
aactgtgaggcctgtgccaaacctctctggcatgtttttaagccacctcctgccctagaa
tgtcgaagatgccatgttaagtgccacagagatcacttagataagaaagaggacttaatt
tctccatgtaaagtaagttatgatgtaacatcagcaagagatatgctgctgttagcgtgt
tctcaggatgaacaaaaaaagtgggtaacacatttggtaaagaagatccctaagaatcca
ccttctggttttgttcgtgcatcccctcgaacgctttctacaagatctgctgcaaatcag
tctttccgaaaagtggtcaaaaatacatctggaaaaactagcagttaa
DBGET
integrated database retrieval system
