Ursus americanus (American black bear): 123783548 Help Entry 123783548         CDS       T07931                                  Symbol ADCY9 Name (RefSeq) adenylate cyclase type 9   KO K08049   adenylate cyclase 9 [EC:4.6.1.1] Organism uar  Ursus americanus (American black bear) Pathway uar00230   Purine metabolism uar01100   Metabolic pathways uar01522   Endocrine resistance uar04015   Rap1 signaling pathway uar04020   Calcium signaling pathway uar04022   cGMP-PKG signaling pathway uar04024   cAMP signaling pathway uar04062   Chemokine signaling pathway uar04072   Phospholipase D signaling pathway uar04081   Hormone signaling uar04082   Neuroactive ligand signaling uar04114   Oocyte meiosis uar04211   Longevity regulating pathway uar04213   Longevity regulating pathway - multiple species uar04261   Adrenergic signaling in cardiomyocytes uar04270   Vascular smooth muscle contraction uar04371   Apelin signaling pathway uar04540   Gap junction uar04611   Platelet activation uar04713   Circadian entrainment uar04714   Thermogenesis uar04723   Retrograde endocannabinoid signaling uar04724   Glutamatergic synapse uar04725   Cholinergic synapse uar04727   GABAergic synapse uar04750   Inflammatory mediator regulation of TRP channels uar04911   Insulin secretion uar04912   GnRH signaling pathway uar04913   Ovarian steroidogenesis uar04914   Progesterone-mediated oocyte maturation uar04915   Estrogen signaling pathway uar04916   Melanogenesis uar04918   Thyroid hormone synthesis uar04921   Oxytocin signaling pathway uar04923   Regulation of lipolysis in adipocytes uar04925   Aldosterone synthesis and secretion uar04926   Relaxin signaling pathway uar04927   Cortisol synthesis and secretion uar04928   Parathyroid hormone synthesis, secretion and action uar04934   Cushing syndrome uar04935   Growth hormone synthesis, secretion and action uar04961   Endocrine and other factor-regulated calcium reabsorption uar04962   Vasopressin-regulated water reabsorption uar04970   Salivary secretion uar04971   Gastric acid secretion uar04972   Pancreatic secretion uar04976   Bile secretion uar05032   Morphine addiction uar05163   Human cytomegalovirus infection uar05166   Human T-cell leukemia virus 1 infection uar05200   Pathways in cancer uar05207   Chemical carcinogenesis - receptor activation uar05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:uar00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     123783548 (ADCY9)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     123783548 (ADCY9)    04371 Apelin signaling pathway     123783548 (ADCY9)    04020 Calcium signaling pathway     123783548 (ADCY9)    04072 Phospholipase D signaling pathway     123783548 (ADCY9)    04024 cAMP signaling pathway     123783548 (ADCY9)    04022 cGMP-PKG signaling pathway     123783548 (ADCY9)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     123783548 (ADCY9)    04081 Hormone signaling     123783548 (ADCY9)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     123783548 (ADCY9)   09144 Cellular community - eukaryotes    04540 Gap junction     123783548 (ADCY9)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     123783548 (ADCY9)    04062 Chemokine signaling pathway     123783548 (ADCY9)   09152 Endocrine system    04911 Insulin secretion     123783548 (ADCY9)    04923 Regulation of lipolysis in adipocytes     123783548 (ADCY9)    04912 GnRH signaling pathway     123783548 (ADCY9)    04913 Ovarian steroidogenesis     123783548 (ADCY9)    04915 Estrogen signaling pathway     123783548 (ADCY9)    04914 Progesterone-mediated oocyte maturation     123783548 (ADCY9)    04921 Oxytocin signaling pathway     123783548 (ADCY9)    04926 Relaxin signaling pathway     123783548 (ADCY9)    04935 Growth hormone synthesis, secretion and action     123783548 (ADCY9)    04918 Thyroid hormone synthesis     123783548 (ADCY9)    04928 Parathyroid hormone synthesis, secretion and action     123783548 (ADCY9)    04916 Melanogenesis     123783548 (ADCY9)    04925 Aldosterone synthesis and secretion     123783548 (ADCY9)    04927 Cortisol synthesis and secretion     123783548 (ADCY9)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     123783548 (ADCY9)    04270 Vascular smooth muscle contraction     123783548 (ADCY9)   09154 Digestive system    04970 Salivary secretion     123783548 (ADCY9)    04971 Gastric acid secretion     123783548 (ADCY9)    04972 Pancreatic secretion     123783548 (ADCY9)    04976 Bile secretion     123783548 (ADCY9)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     123783548 (ADCY9)    04961 Endocrine and other factor-regulated calcium reabsorption     123783548 (ADCY9)   09156 Nervous system    04724 Glutamatergic synapse     123783548 (ADCY9)    04727 GABAergic synapse     123783548 (ADCY9)    04725 Cholinergic synapse     123783548 (ADCY9)    04723 Retrograde endocannabinoid signaling     123783548 (ADCY9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     123783548 (ADCY9)   09149 Aging    04211 Longevity regulating pathway     123783548 (ADCY9)    04213 Longevity regulating pathway - multiple species     123783548 (ADCY9)   09159 Environmental adaptation    04713 Circadian entrainment     123783548 (ADCY9)    04714 Thermogenesis     123783548 (ADCY9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     123783548 (ADCY9)    05207 Chemical carcinogenesis - receptor activation     123783548 (ADCY9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     123783548 (ADCY9)    05163 Human cytomegalovirus infection     123783548 (ADCY9)   09165 Substance dependence    05032 Morphine addiction     123783548 (ADCY9)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     123783548 (ADCY9)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     123783548 (ADCY9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     123783548 (ADCY9) Enzymes [BR:uar01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      123783548 (ADCY9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N Motif Other DBs NCBI-GeneID:  123783548 NCBI-ProteinID:  XP_045640295 LinkDB All DBs Position Unknown AA seq 1352 aa AA seqDB search MASPPHQQLLQHHSTEVSCDSSGDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDS GGVPRRVGAGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACMERCFPQTQRRFRYAL FYIGFACLLWSIYFGVHVRSKLIVMVAPALCFLVVCVGFFLFTFTKLYARHYVWTSLVLT LLVFALTLAAQFQVLTPLSGRVDSSNHTLAAKPTDTCLSQVGSFSMCIEVLFLLYTVMHL PLYLSLFLGVVYSVLFETFGYHFRDKDCFPPPGAGAPHWELLSRALLHLCIHAIGIHLFI MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKR HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEQFCQEK KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD DRYEMEDGKVTERLGQSVVADQLKGLKTYLIAGQRAKESHCSCSEALLSGFEVIDGSRVS SGPRRQGTASPGSVSDLAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGAVQNGCQEEHKN STKAPGAPNSKTQNGLLSPPQEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNI REKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELERSYRTSYQEEVIKNSPVKTF ASATFSSLLDVFLSTTVFLILSITCFLKYGAATTAPPPAALAVFSAALLLEMLSLVVSIR MVFFLEDVMACTKRLLEWIAGWLPRHFIGAILVSLPALAVYSHVTSEFETNIHFTVFMGS AVLITVVHYCNFCQLSSWMRSSLATVVGAGPLLLLYVSLCPDSSIVISHLDAGQNFSSEG NPCNSSLPRDGGTASLIGQEVILVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKI QSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKEC YRVLNELIGDFDELLSRPGYSSIEKIKTIGATYMAASGLNGAQCQDGSHPQEHLQVLFEF AKEMMRVVDDFNSNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDSTG VECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCMDSGAVPQHQLSISPD IRVQVDGSIGRSPTDEIANLVPSVQNADKMSLGSENNVQAKDIHLSSKRPWKEPFKAEER CRFGKAIEKSDCEEAGMEEASELTRLNVSKSV NT seq 4059 nt NT seq  +upstreamnt  +downstreamnt atggcttccccaccccaccagcagctgctgcagcaccacagcaccgaggtgagttgtgac tccagcggagacagcaacagcgtgagggtcaaaattaaccccaagcagctgtcctccaac agccaccccaagcactgcaagtacagcatctcctccagctgtagcagctctggggactca gggggtgtcccccggagagtgggcgctggaggccgcctgcgcaggcagaagaagctgccc cagctgttcgagagggcctccagccgatggtgggaccccaagttcgactccgtgaacctg gaggaggcttgcatggagcgctgcttcccgcagacccagcgccgcttccgatatgcgctc ttctacatcggcttcgcctgccttctgtggagcatctattttggggtccacgtgaggtcc aaactgattgtcatggtagccccagctctgtgcttcctcgtagtgtgtgtgggctttttt ctgtttaccttcaccaagctgtatgcccggcattacgtgtggacctctctggttctcacc ctcctggtgttcgccctgaccctggctgcccagtttcaggttttgacgcctctctcagga cgtgttgacagctccaatcataccctcgcagccaagcccacagacacttgcttatctcaa gtggggagcttttccatgtgcatcgaagtgctctttttactctacacggtcatgcactta cctttgtacttgagcttgtttttgggagtggtctattctgttctctttgagacctttggc tatcatttccgagacaaagactgctttcccccacctggagcaggggcgccacactgggag ttgctgagccgagccctgctccacctctgcattcatgccattgggatccacctatttatc atgtcccaggtgagatctcggagcacctttctcaaggtgggacagtcaattatgcatgga aaggatctggaagtggaaaaagccctgaaagagaggatgattcattctgtgatgccaaga atcatagctgatgacctgatgaaacagggggatgaggagagcgagaattctgtcaaaagg cacgcgacctccagccccaagaacaggaagaaaaagtcttccatacagaaagcccctata gcattccgccctttcaaaatgcagcagatagaagaagtcagtattttatttgcagatatc gtgggcttcacaaagatgagtgccaataagtctgctcacgccctggtgggtctcctcaac gatttgtttggtcgctttgaccggttgtgtgaagagaccaagtgtgagaaaattagtacc ctgggagactgctactattgtgtggcggggtgtccggagccccgggccgaccatgcctac tgctgcattgagatgggcttgggcatgatcagagctatcgagcaattctgccaggagaag aaagagatggtgaacatgcgtgtcggggttcacacggggactgtcttgtgcggcattttg ggcatgaggaggttcaaattcgatgtgtggtccaatgatgtgaacttggccaatctcatg gagcagctgggagtggcgggcaaggttcacatttctgaggccacagcaaaatacctagat gatcggtacgaaatggaagatgggaaagttactgaacgccttggccagagcgttgttgct gaccagttgaaaggtttgaagacatacctgatagcgggtcagagagcgaaggagtctcat tgcagctgctcagaggccttgctttctggctttgaggtcattgacggctcacgggtgtcc tcaggtcctaggagacaggggacagcatcgccagggagtgtcagtgacttggcgcagact gtcaaaacctttgataaccttaagacctgtccttcatgcggaatcacgtttgcccccaaa tcggaagctggtgcagaaggaggagcggtccaaaatggctgtcaagaggagcataaaaac agcaccaaggctcctggagcaccgaattccaaaactcagaatggacttctgagccctccc caagaggaaaagctcaccaacagtcagacctccctgtgtgagatcttacaggaaaaggga aggtgggcaggagtgagcttggaccagtcagctctccttccgctgagattcaagaacatc cgggagaaaacagatgcccattttgtcgatgttatcaaagaagacagcctgatgaaagat tattttttcaagccacccatcaatcagttcagcttgaacttcctggatcaggagctagag cgatcctataggaccagctaccaagaagaggttataaagaattctcccgtgaagactttt gccagtgccaccttcagctccctcctggatgtgtttctttcgacgacagtgtttctaatt ctctctatcacctgcttcctgaagtacggggctgccaccacggctcccccgcctgccgcc ctggcagtcttcagcgccgccctgctgctggagatgctgagccttgtggtctccatcagg atggtgtttttcctggaggatgtgatggcctgtacgaagcgcctgctggagtggatagcc ggctggctcccgcgccatttcattggggccatcctggtgtcactccctgctcttgcagtc tattcacatgtcacctctgaatttgagacaaacatacacttcaccgtgtttatgggctca gccgtcctgatcaccgtcgtgcactactgtaacttctgccagctcagctcctggatgagg tcctccttagccacagtcgtcggggctgggcccctgctcctgctctatgtctccctgtgc cctgacagttccatagtaatttcacaccttgatgcaggacagaatttcagttccgagggg aatccgtgcaatagttccttgccacgtgatggcggaacggccagcctgattggccaggag gtgattcttgtcttctttctcctgctcctgttggtctggttcctgaatcgagaattcgag gtcagctaccgcctgcactaccatggggacgtggaggcggaccttcaccgcaccaagatc cagagcatgagggaccaagctgactggctgctgagaaacatcatcccctaccacgtggcc gagcagctgaaggtctcacagacctactccaagaaccacgacagcggaggtgtcatcttc gccagcatcgtcaacttcagtgagttctacgaggagaactacgaggggggcaaggagtgc taccgggtcctcaacgagctcatcggggacttcgacgagctcctgagcaggccgggctac agcagcatcgagaagatcaagaccattggggccacgtacatggctgcatcgggtctgaat ggcgcccagtgccaggacggcagccacccgcaggagcacctgcaggtcctgtttgagttc gccaaggagatgatgcgcgtggtggacgacttcaacagcaacatgctgtggttcaacttt aagctcagggtcggcttcaaccatgggccgctcacagcgggggtcatcggcaccaccaag ctgctgtatgacatctggggcgacactgtcaacatcgccagcaggatggacagcacaggg gtggagtgccgcatccaggtgagcgaggagagctaccgcgtcctgagcaagatgggctac gacttcgactaccgggggacagtgaacgtgaagggcaagggccagatgaagacctacctg tacccaaagtgcatggacagcggggccgtgccacagcaccagctgtccatctccccggac atccgagtccaggtggacggcagcattgggcggtctcccacggacgagatcgccaacctg gtgccttctgtacagaatgcagacaagatgtctctgggttccgaaaacaacgttcaggcc aaggacattcacctgtcctctaagaggccgtggaaagagcccttcaaagccgaagaaagg tgtcgatttggcaaagccatagagaaaagtgactgtgaagaagctggcatggaggaagcc agcgagctcaccaggctcaatgtttccaagagcgtgtga

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