| Entry |
|
|---|
| Symbol |
ABCC2
|
|---|
| Name |
(RefSeq) ATP-binding cassette sub-family C member 2
|
|---|
| KO |
| K05666 | ATP-binding cassette, subfamily C (CFTR/MRP), member 2 |
|
|---|
| Organism |
uar Ursus americanus (American black bear)
|
|---|
| Pathway |
| uar04981 | Folate transport and metabolism |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:uar00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
123783559 (ABCC2)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
123783559 (ABCC2)
04981 Folate transport and metabolism
123783559 (ABCC2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
123783559 (ABCC2)
01523 Antifolate resistance
123783559 (ABCC2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:uar02000]
123783559 (ABCC2)
Transporters [BR:uar02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
123783559 (ABCC2)
|
|---|
| SSDB |
|
|---|
| Motif |
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| Position |
Unknown
|
|---|
| AA seq |
1541 aa
MLEKFCNSTFWNSSLLDSPEADLPLCFEQTVLVWIPLGFLWLLAPWQLLHVYRSKIEKSP
ITKLYLAKQVLVGFLLILAAIELALVLTEDSGQVTVPAIRYTNPSLYLGTWLLVLLIQHS
RLWCMQKDSWFLSLFWILSILCGVFQFQTLIRILLKGNNSNLAYSCLFFVSYALQILILV
LSAFSEKDASSNNPSFTASFLSNITFSWYDSTVMKGYKQPLTLEDVWDVDEEIKTKALVS
TFEKHMVGELQKARKALQRRQRRKAQRNTGDGPHGLNKNQSQSQDILVLEEVKKKKKSGT
TKNFPKSWLVKTLFKTFYIVLLKSFFLKLVHDLLMFLNPQLLKLLISFANDRGTYIWTGY
LYSVLFFVVALIQSLCLQGYFQMCFKLGVTVRTTILASIYKKALTLSNQARKQYTIGETV
NLMSVDAQKLMDVTSYLHLLWSNVLQITLSIYFLWAELGPSVLAGVGVIVLLIPVNGILA
AKSRAVQVKNMKNKDKRLKIMNEILSGIKILKYFAWEPSFKNQVHELRKKELKNLLAFAR
MQSVMVFLLHLTPVLVSVITFSVYTLVDSNNILDAEKAFTSITLFNMLRFPLSMFPMVIS
TVLQASVSRDRLEQYLGGDDLDTSAIRHDCNSDKAVQFSEASFTWDQDSEATIRDVNLDI
TPGQLVAVVGAVGSGKSSLMSAMLGEMENVHGHVTIKGTVAYVPQQSWIQNGTIKNNILF
GSEFDEKRYQQILEACALLQDLEVLPGGDLAEIGEKGINLSGGQKQRISLARATYQNSDI
YVLDDPLSAVDAHVGKHIFNKVLGPNGLLKGKTRLLVTHSIHFLPQVDEIVVLGNGTILE
KGSYSTLLAKKGPFAKILKTFTKQTGPEEEATVNEDTEEEDDCGLMPSVEEIPEDVAALT
MKRENSLHRTLSRRSNSRHRKSLRNSLKTRNVNTLKEEEELVKGQKLIKKEFMETGKVKF
SIYLKYLRAIGWCSIFFIVFAYVINSVAYIGSNLWLSAWTNDSKTYNGTNYPASQRDLRI
GVYGALGLAQGAFVLMANLWSAHGSTYASGILHRQLLSNILQAPMSFFDTTPTGRIVNRF
AGDISTVDDTLPLSLRSWILCFLGIISTLVMICTATPVFVVVIIPLGIIYVSVQIFYVAT
ARQLKRLDSVTRSPIYSHFSETVSGLSVIRAFEHQERFLKHNEVGIDTNQKCVFSWIVSN
RWLAIRLELIGNLIVFFSSLMMVIYRDTLSGDTVGFVLSNALNITQTLNWLVRMTSEIET
NIVAVERINEYIKVENEAPWVTDERPPAGWPSKGEIHFNNYQVRYRPELDLVLRGITCDI
RSMEKIGVVGRTGAGKSSLTNALFRILEAAGGQIIIDGVDIASIGLHDLREKLTIIPQDP
ILFSGTLRMNLDPFNNHSDEEIWKALELAHLKSFVSGLQLGLSHEVTEAGDNLSIGQRQL
LCLARALLRKSKVLIMDEATAAVDLETDHLIQTTIQEEFSHCTTITIAHRLHTIMDSDKI
MVLDNGKIVEYGSPQELLRSSGPFYLMAKEAGIENVNSTSF |
|---|
| NT seq |
4626 nt +upstreamnt +downstreamnt
atgctggagaagttctgcaactctacgttttggaattcttcactcttggatagcccagaa
gcggacctgccactttgttttgagcaaactgttctggtgtggattcccttgggtttcctt
tggctcctggccccttggcagcttcttcatgtgtatagatccaaaatcgagaaatctcct
ataaccaaactctacctcgctaagcaggtgcttgttgggtttcttcttattctagcagcc
atagagctggcccttgtactcacagaagactctggacaagtcacggttcctgccattaga
tacaccaatccaagcctttacctgggaacatggctcctggttttgctgatccaacacagc
agactgtggtgcatgcagaaggattcttggttcctgtccctgttctggattctctcaata
ctctgtggcgttttccagtttcagactctgatccggatactcttgaagggcaacaattct
aacctggcctattcctgcctgttcttcgtcagctatgcactgcagatcctgatcctggtc
ctttcagcattttcagaaaaagatgcctcctcaaataatccatcattcacagcctcgttt
ctgagtaacattacgtttagctggtatgacagcactgttatgaaaggctacaagcaacct
ctgactcttgaagatgtctgggatgtcgatgaagagattaaaaccaaagcgctggtcagc
acgtttgaaaaacatatggtaggagagctgcagaaggccaggaaggcgctccagagacgg
cagcggaggaaggcccagcggaacactggagacgggccacatggcttgaacaagaatcag
agtcaaagccaagatatccttgtcctggaagaagttaaaaagaaaaaaaagtctgggacc
acaaaaaactttcccaaatcctggttggtcaagactctcttcaaaactttctacattgtt
ctcttgaaatcattcttcctgaagctggtgcatgacctcctcatgtttctgaatcctcag
ctgctgaaattgctgatctccttcgcaaatgaccgaggcacgtatatatggaccggatat
ctctactcagtcctcttctttgttgtggccctcatccagtccctctgccttcagggctac
tttcagatgtgcttcaagctgggcgtcactgtacggacaaccatcctggcgtccatatat
aagaaggcgctgaccctatccaaccaggccaggaagcagtacaccattggagaaacagtg
aacctgatgtctgtggatgcccagaagctcatggatgtgaccagctaccttcatctgctg
tggtcaaatgttctccagattactttgtctatctacttcctatgggcagagctgggaccc
tctgtcttagcaggtgttggggtgatagtactcctaattccagttaatgggatacttgct
gccaagagtagagctgttcaggtaaaaaatatgaagaataaagacaaacggttaaagatc
atgaatgaaattctcagtgggatcaagatcctgaaatattttgcctgggaaccttcattc
aaaaaccaagttcatgaacttcggaagaaagagctcaagaacctgctggcctttgcacgg
atgcagtctgtaatggtgtttctcttacacttaactcccgtcctggtgtctgtgatcaca
ttttcagtctacactctggtggacagcaataatattctggatgcagaaaaggccttcacg
tccatcaccctcttcaacatgctgcgctttcccctcagcatgtttcccatggtgatctcc
accgtcctccaggccagtgtttccagagaccggctagaacagtacttgggaggggatgac
ttggacacatccgccattcgacatgactgcaattctgacaaagctgtgcagttttcggag
gcctcctttacctgggaccaggactcggaagccacaatccgagatgtgaacctggacatt
acgccaggccagttggtggctgtggtgggtgctgtgggctctgggaagtcctccttgatg
tcagccatgctgggagaaatggaaaacgtccacgggcacgtaaccatcaagggcaccgta
gcctacgtcccacagcaatcctggatccagaacggcaccataaagaacaacatccttttt
ggatctgagtttgatgaaaagagataccagcagattctggaggcctgtgccctcctccaa
gacttggaagtgctgcctggaggagacctggccgagattggagagaagggtataaatctc
agcgggggtcagaagcagaggattagcctggccagagctacctatcagaactcggacatc
tatgtcctggatgaccccctgtcggctgtggatgctcatgtgggaaaacatattttcaat
aaggtcttggggcccaatggcctactgaaaggcaagactcgactcttggttacgcatagc
attcactttcttccccaagtggatgagatcgtggttctggggaatggcaccatcttggag
aagggatcttacagcactctgctggccaagaaaggaccatttgctaagattctgaagacg
ttcacaaaacagacgggtcctgaggaagaggccacagtcaatgaggacactgaagaagaa
gatgactgtgggctgatgcccagtgtggaggaaatccctgaggatgtggccgccttaacc
atgaaaagagagaacagccttcatcgaacacttagccgcaggtccaacagcaggcatcgg
aaatccctaagaaactctttgaaaactcggaatgtgaacaccctgaaggaggaggaggaa
ctagtgaaaggacaaaaactaattaagaaggaattcatggaaactggaaaggtgaaattc
tccatctacctgaagtacctacgagcaataggatggtgttcaatattctttatcgtcttt
gcctatgtgatcaattccgtggcttatattggatccaacctctggctcagtgcttggacc
aatgactctaaaacctataatggcactaactatccagcatctcagagggacctgagaatt
ggtgtctatggagctctgggattagcacaaggtgcgtttgtgctcatggcaaatctctgg
agtgcccatggttctacgtacgcatcaggcattcttcataggcaactgctaagcaatatc
cttcaagcacccatgagtttttttgacacaacacccacaggccggattgtgaacaggttt
gctggtgatatttccacagtggatgacacccttcccttatccttgcgcagctggatattg
tgttttctgggaataatcagcacccttgtcatgatttgcacggccactccagtcttcgtt
gtcgtcatcattcctcttggcatcatttatgtgtccgttcagatattttatgtggccact
gcccgccagctgaaacgtctggactctgtcaccaggtccccgatctactctcacttcagt
gagactgtgtcaggtttgtctgtcatccgtgcctttgagcaccaggagcgatttctgaaa
cacaacgaggtggggattgacaccaaccagaaatgtgtcttctcctggattgtctccaac
aggtggcttgcaattcgtctggagctgattgggaacctgattgtcttcttttcatccctg
atgatggttatttatagagataccctaagtggagacactgtgggctttgttctgtccaat
gcgcttaatatcacacagaccctgaactggctagtgaggatgacgtcagaaatagagacc
aacattgtggctgttgaaagaataaatgagtacataaaagtggaaaacgaggcaccctgg
gtaactgatgagagacctcccgcaggttggcccagcaaaggggagatccattttaacaac
taccaagtgcggtaccggccggagctggatcttgtcctgagagggatcacttgtgacatt
aggagcatggagaagattggtgtggttggcaggacaggagctgggaagtcctccttgaca
aatgccctcttcagaatcctggaggctgcaggtggccagatcatcatcgatggagtagat
attgcttccattgggctccatgacctccgggagaaactaacaatcatcccccaggatccc
atcctgttctctggaaccctgaggatgaacctagacccttttaacaaccactcagatgag
gagatttggaaggccctggagctggctcacctcaaatcctttgtgtctggcctgcaactt
gggttgtctcacgaagtgacagaggctggtgacaaccttagcatcgggcagaggcagttg
ctgtgcctggcccgggctctgcttcggaaatccaaggttctgatcatggacgaggccact
gccgccgtggatctggagaccgatcacctcatccagacgaccatccaggaggagttctcc
cactgcaccaccatcaccattgctcacagactgcacaccatcatggacagcgacaagata
atggtcctagacaatgggaagattgtagagtatggcagccctcaggaactgctgagaagt
tcgggccccttctatctgatggccaaagaagctggcattgaaaatgtgaacagcacatca
ttctga |
|---|
