Ursus americanus (American black bear): 123784330
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Entry
123784330 CDS
T07931
Symbol
PAK4
Name
(RefSeq) serine/threonine-protein kinase PAK 4
KO
K05734
p21-activated kinase 4 [EC:
2.7.11.1
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar04012
ErbB signaling pathway
uar04014
Ras signaling pathway
uar04360
Axon guidance
uar04510
Focal adhesion
uar04660
T cell receptor signaling pathway
uar04810
Regulation of actin cytoskeleton
uar05170
Human immunodeficiency virus 1 infection
uar05206
MicroRNAs in cancer
uar05211
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
123784330 (PAK4)
04014 Ras signaling pathway
123784330 (PAK4)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
123784330 (PAK4)
09142 Cell motility
04810 Regulation of actin cytoskeleton
123784330 (PAK4)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
123784330 (PAK4)
09158 Development and regeneration
04360 Axon guidance
123784330 (PAK4)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
123784330 (PAK4)
09162 Cancer: specific types
05211 Renal cell carcinoma
123784330 (PAK4)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
123784330 (PAK4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uar01001
]
123784330 (PAK4)
Enzymes [BR:
uar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
123784330 (PAK4)
Protein kinases [BR:
uar01001
]
Serine/threonine kinases: STE group
STE20 family
123784330 (PAK4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PBD
Kinase-like
ABC1
Pkinase_fungal
hnRNP_Q_AcD
RIO1
Kdo
KIND
Motif
Other DBs
NCBI-GeneID:
123784330
NCBI-ProteinID:
XP_045641619
LinkDB
All DBs
Position
Unknown
AA seq
596 aa
AA seq
DB search
MFGKKKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT
SIQPGAPKTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRRDSPPPPARARQENGMPAE
AASTARGAPEKAGSQGRGTGRSEAGGSSGDRRRVGPEKRPKSSREGSGGPQESSRDKRPL
SGPDVGSPQPAGLAGGAKAAAGRPFNTYPRADTDHPARGAQGEPHNLAPNGPSAGGLAVP
QSSSSRPPARARGPPSPGVLGPHASEPQLAPPARPVAAPAPAPAGPPAPGPPGPRSPQRE
PQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGRLVAVKKMDLR
KQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEE
QIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSL
VGTPYWMAPELISRLPYGPEVDIWSLGVMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRL
KNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR
NT seq
1791 nt
NT seq
+upstream
nt +downstream
nt
atgtttgggaagaagaagaaacgggtcgagatctctgcgccatccaacttcgagcaccgc
gtgcacacgggcttcgaccagcacgagcagaagttcacggggctgccccgccagtggcag
agcctgatcgaggagtcggctcgccggcccaagcccctggtggaccccgcctgcatcacc
tccatccagcccggggcccccaagaccatcgtgcggggcagcaaaggcgccaaggatggg
gccctcacgctgctgctcgacgagtttgagaacatgtcggtgacacgctccaactccctg
cggagagacagcccaccgccacctgcccgtgcccgccaggaaaatgggatgcccgcagag
gcggccagcacggccagaggggccccggagaaggcgggcagccaaggccggggcaccggc
cgcagcgaggcgggtggcagcagtggtgacaggcggcgggtggggccagagaagaggccc
aagtcttccagggagggctcagggggaccccaggagtcctcccgggacaaacgccccctc
tctgggcctgacgtcggcagcccacaacctgccggtctggctggtggagccaaagcggca
gctggtcggccctttaacacgtacccgagggccgatacggaccacccggcccggggtgcc
cagggggaacctcacaacctggcccccaacgggccatcagcagggggcctggcggtcccc
cagtcctcctcctcccggcctcccgcccgagcccgcggaccccccagcccaggagtgctg
ggcccccatgcctctgagccccagctggctcctccagcccgccctgtcgctgcccccgcc
cccgcccccgccgggcccccagcccccgggccccccgggccccgctcaccgcagcgggaa
ccccagcgagtgtcgcacgagcagttccgggcagccttgcagctggtggtggaccccggc
gaccctcgctcctacctggacaacttcatcaagatcggcgagggctcgacgggcatcgtg
tgcattgctaccgtgcgcagctctggcaggctggtggctgtcaagaagatggacctgcgc
aagcagcagaggcgcgagctgctcttcaacgaggtggtgatcatgcgggactaccagcac
gagaacgtggtggagatgtacaacagctacctggtcggggatgagctctgggtggtcatg
gagttcctggagggcggcgccctcaccgacatcgtcacgcacaccaggatgaatgaggag
cagattgccgccgtgtgcctggccgtgctgcaggccctgtctgtgctccacgcacaggga
gtcatccaccgcgacatcaagagcgactccatcctgctgacccacgacggcagggtgaag
ctgtcagacttcgggttctgcgcccaggtgagcaaggaggtaccacggaggaagtcactg
gttggcacgccctactggatggccccagagctcatctctcgccttccctatgggccagag
gtggacatctggtctctgggggtgatggtgatcgagatggtggacggggagcccccctac
ttcaatgagccgccgctcaaagccatgaagatgattcgggacaacctgccgccccgactg
aagaacttgcacaaggtgtcaccctccctgaagggcttcctggaccgcctgctggtgcgt
gacccggcccagcgggccacggcggctgagctgctcaagcacccattcctggccaaagcg
ggcccgcccgccagcatcgtgcccctcatgcgccagaaccgcaccagatga
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