Ursus americanus (American black bear): 123786391 Help Entry 123786391         CDS       T07931                                  Symbol PLD1 Name (RefSeq) phospholipase D1 isoform X1   KO K01115   phospholipase D1/2 [EC:3.1.4.4] Organism uar  Ursus americanus (American black bear) Pathway uar00564   Glycerophospholipid metabolism uar00565   Ether lipid metabolism uar01100   Metabolic pathways uar04014   Ras signaling pathway uar04024   cAMP signaling pathway uar04071   Sphingolipid signaling pathway uar04072   Phospholipase D signaling pathway uar04144   Endocytosis uar04666   Fc gamma R-mediated phagocytosis uar04724   Glutamatergic synapse uar04912   GnRH signaling pathway uar04928   Parathyroid hormone synthesis, secretion and action uar05200   Pathways in cancer uar05208   Chemical carcinogenesis - reactive oxygen species uar05212   Pancreatic cancer uar05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:uar00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     123786391 (PLD1)    00565 Ether lipid metabolism     123786391 (PLD1)  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     123786391 (PLD1)    04072 Phospholipase D signaling pathway     123786391 (PLD1)    04071 Sphingolipid signaling pathway     123786391 (PLD1)    04024 cAMP signaling pathway     123786391 (PLD1)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     123786391 (PLD1)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     123786391 (PLD1)   09152 Endocrine system    04928 Parathyroid hormone synthesis, secretion and action     123786391 (PLD1)   09156 Nervous system    04724 Glutamatergic synapse     123786391 (PLD1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     123786391 (PLD1)    05208 Chemical carcinogenesis - reactive oxygen species     123786391 (PLD1)    05231 Choline metabolism in cancer     123786391 (PLD1)   09162 Cancer: specific types    05212 Pancreatic cancer     123786391 (PLD1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:uar04131]     123786391 (PLD1) Enzymes [BR:uar01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.4  Phosphoric-diester hydrolases     3.1.4.4  phospholipase D      123786391 (PLD1) Membrane trafficking [BR:uar04131]  Exocytosis   Calcium ion-dependent exocytosis    Phospholipases     123786391 (PLD1)  Endosome - Golgi transport   Others    Others     123786391 (PLD1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PLDc PX PLDc_2 PH DUF3785 zf-C2H2_7th_ZNF462 Motif Other DBs NCBI-GeneID:  123786391 NCBI-ProteinID:  XP_045644603 LinkDB All DBs Position Unknown AA seq 1074 aa AA seqDB search MSLKNEPRVNTSALQKIAADMSNLIENLDTRELHFEGEEVDYDVSPSDPKTQEACIPFSA IYKTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVKEEPREMPSLPRSSENMIREEQFFGRR KQLEDYLTKLLKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGLRID NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTDFLKDHRFGSYAAVQENTLAKWYVNAKG YFEDVASAMEEAEEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFVMLY KEVELALGINSEYSKRTLMRLHPNIKVMRHPDHVSSSVYLWAHHEKLVVIDQSVAFVGGI DLAYGRWDDNEHRLTDVGSVKRVTVGSSLGSFTAETTGSMESLSLKDKNEPSKNPPTLKS VDDMDSKLKGIGKSRKFSTFSLYRQLHRQHVHKADSVSSLDSASSYCNHCRSRQNLIHGL KPHLKLFRSSSKSEQGLARPDVDTSSVRSLQTGMGELHGETRFWHGKDYCNFVFKDWVQL DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL PKSQTTAHELKYQVPGSVSASVQLLRSAADWSAGIKYHEESIHTAYVHVIENSKHYIYIE NQFFISCADDKVVFNKIGDAIAQRILKAHRESQRYRVYVVIPLLPGFEGDISTGGGNALQ AIMHFNYRTMCRGENSILGQLNAKLGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGEEYQAGRFAQGLRLQCF RVVLGYLSDPSENIQDPVSDKFFKEVWVATAARNATIYDKVFRCLPNDEVHNLIQLRDFI TKPILAREDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPTEVWT NT seq 3225 nt NT seq  +upstreamnt  +downstreamnt atgtccctgaaaaatgagccaagagtaaatacctctgcactgcagaaaatcgctgctgac atgagtaatttgatagaaaatctggacacgcgggagctgcactttgagggagaggaggtg gattacgatgtgtctcccagcgatcccaagacacaggaagcgtgtattccgttctctgct atttataagactcaaggatttaaggagcctaacatacagacgtatctctccggctgtcca ataaaagcccaagtcctggaagtggaacgctttacgtctacaacaagggtaccaagtatc aatctttacactattgaattaacacatggggagtttaagtggcaagttaagaggaaattc aagcactttcaagaatttcacagagagctgctcaagtacaaagcttttatccgaatcccc attcccactagaaggcacacatttagaagacagaatgtcaaagaagagcctcgagagatg ccaagtttgccccgttcatctgaaaacatgatcagagaagaacaattctttggcagaagg aaacaactggaagattatttgacaaagctactaaaaatgcccatgtatagaaactaccat gcgacaacagaattccttgacataagccagctgtctttcatccatgatttgggaccaaag ggcatagaaggtatgataatgaaaagatccgggggacacagaataccaggcttgaattgc tgtggtcagggaagagcctgctaccgctggtcaaaaaggtggttgatagtgaaagattca tttttattatatatgaagccagacagcggtgctattgcctttgtgctgctggtagataaa gaattcaaaattaaggtggggaagaaggagacagagacgaaatatgggctccgaatcgat aatctttcaaggacacttattttaaaatgcaacagctatagacatgctcggtggtgggga ggggctatagaagaattcatccagaaacacggcaccgactttctcaaagaccatcgattt gggtcgtatgctgctgtccaggagaatactttagctaaatggtacgttaatgccaaaggg tattttgaagatgtggcaagtgctatggaagaggcagaagaagagatttttatcacggat tggtggttgagtccagaaatcttcctgaaacgcccggtggttgaaggaaatcgttggagg ttggactgcattctcaagcgaaaagcacaacagggagtgagaatctttgtaatgctgtac aaagaggtagaacttgctctcggaatcaacagtgaatacagcaagaggactctcatgcgt ctacaccccaacataaaggtgatgaggcacccagatcatgtatcatccagtgtatatcta tgggctcatcatgagaaacttgttgtcatcgaccagtcagtggcctttgtgggtgggatt gacctggcctatggaaggtgggatgacaatgaacacagactcacagacgtgggcagtgtg aagcgtgtcaccgtaggatcgtctctgggttccttcactgctgaaacaacagggtccatg gaatccttgagcctcaaagacaaaaatgaacctagtaaaaatccgcctaccctgaagagt gttgatgatatggattcaaaactgaaaggaataggaaagtccagaaagttctctacattc agcctctacaggcagctgcacaggcagcacgtacacaaggcggacagcgtcagcagcctg gacagcgcctccagttattgtaatcactgtagaagtcgtcagaatttaatccatggttta aaaccccacctgaaactctttcgctcctccagtaagtctgagcagggcctcgctagacct gacgtggacaccagctccgtccgcagtttgcagacaggcatgggagagctccatggggag acgaggttctggcatgggaaggactactgcaattttgtcttcaaagactgggttcaactg gataagccttttgctgatttcattgacagatactccactccccggatgccgtggcatgac attgcctctgcggtccacgggaaggcggctcgtgacgtggcccgtcacttcatccagcgc tggaacttcacgaagattatgaagtccaaatatcggtccctctcttatcctttcctgctt cccaaatcgcaaacaacagcccatgagttgaaatatcaagtgcctgggtccgtcagtgcc agtgtacagctgcttcgctccgctgctgactggtcggctggtataaagtaccatgaagag tccatccacactgcttacgtccacgtgatagagaacagcaagcactacatctatatagaa aaccagtttttcataagttgcgctgatgacaaagttgtgttcaacaagataggtgatgcc attgctcagaggatactgaaagctcacagggaaagccagagataccgggtgtatgtggtg atcccactgctgccagggtttgaaggagacatctcaaccggtggaggaaacgctctgcag gcaataatgcacttcaactacaggaccatgtgcagaggagaaaattccatccttggacaa ttaaacgcaaagcttggcaatcagtggataaattacatatcattctgtggccttcgaaca catgcagagcttgaaggaaatctagtcactgagctcatctacgtccacagcaagttgcta attgctgatgacaacactgttattattggctctgccaacatcaacgaccgaagcatgctg ggaaagcgtgacagtgaaatggctgtcattgtgcaggacacggagacggtcccttcggtg atggacggagaagagtaccaggctggccgcttcgcccagggacttcggctgcagtgcttc agggttgtccttggctatctttctgacccaagtgaaaacattcaggatccagtgagtgac aaattcttcaaggaggtgtgggttgcaacggcagctcgaaatgctacaatttatgataag gtgttccggtgccttcccaatgatgaagtacacaatttaattcaactgagagactttata accaagcccatcttggcaagggaagatcccattagagctgaggaagaactgaagaagatc cgcgggttcttagtgcaattccccttttatttcctgtctgaagaaagcctactgccttcc gttggaaccaaagaagccatagtgcccacagaggtttggacttaa

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